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The map label for this gene is gntK [H]

Identifier: 118475928

GI number: 118475928

Start: 167536

End: 169167

Strand: Direct

Name: gntK [H]

Synonym: BALH_0159

Alternate gene names: 118475928

Gene position: 167536-169167 (Clockwise)

Preceding gene: 118475927

Following gene: 118475929

Centisome position: 3.19

GC content: 38.91

Gene sequence:

>1632_bases
TTGAGGCCTTACATCAAAACTTTGATGATGTTCAAGGGAAAGTCGAAGACCTCTGGATGTCGCAACAAATGTTATCTAAA
GGAGTTGAGCAAGGACATGAGTAGCTATATGTTAGGTATAGATATCGGTACAACAAGTACGAAAGCAGTTTTATTTACTG
AAAAAGGCGAAGTCATCCAAACCGAGAATATTGGTTATCCACTTCGCACACCGGATATATCCACAGCGGAACAAGATCCA
GAAGAGATTTTCCAAGCTGTTTTACAAGCGATATCAAATATAACGAAACAGCATTCAGATAAAAAAACATCGTTTATTTC
ATTTAGCAGTGCTATGCATAGTGTCATTGCTATGGATGAAAATGATCAGCCGCTGACACCTTGTATCACTTGGGCAGATA
ATCGTAGTGAGGCATGGGCGCATAAAATCAAAGATGAACTGAATGGCCATGCAGTTTATAGACGAACTGGAACACCTATT
CACCCAATGTCACCATTAAGTAAAATTACATGGATTGTGAATGCCCATCCGGAAATTGCTATTAGAACGAAAAAATATAT
TGGAATCAAAGAATATATCTTCAAAAAATTCTTTGATCAATATGTTGTTGATCATTCCATCGCCTCGTGCATGGGTATGA
TGAACTTAAAAACGCTAGATTGGGATGAGGAAGCTTTAAAAATTGCTGGTATAACATCAGCTCAATTATCTAAACTCGTA
CCAACCACCAAAATATTCAGCAACTGCAATCCAGATTTAGCCCAAAAGATTGGTATCGATTCCAAAACACCGTTTGTCAT
TGGTGCTAGTGATGGGGTGCTTTCTAATCTAGGTGTGAATGCAATTCGGAAAGGGGAGATTGCTGTCACAATTGGAACCA
GTGGTGCTATTCGGACCATCATTGATAAACCACAAACAGATAAAAAAGGAAGAATATTTTGTTATGCCTTAACCGAAAAA
CATTGGGTAATTGGTGGACCGGTAAACAATGGAGGGATGGTCCTTCGCTGGATTCGTGATGAACTTGCTTCATCAGAAGT
AGAAACTGCGAAAAGACTAGGAATTGATCCATACGATGTATTAACTAAAATAGCAGAACGCGTGAGACCTGGTGCAGACG
GATTATTATTCCATCCATACCTCGCAGGGGAACGTGCACCATTATGGAATCCAGATGTACGTGGCTCCTTCTTCGGTTTA
ACGATGTCACATAAGAAGGAACATATGATTCGTGCAGCTTTAGAGGGTGTTATATATAATTTATACACTGTATTTTTAGC
ATTAACAGAATGTATGGATGGTCCTGTAACTCGTATTCAAGCAACAGGCGGCTTCGCAAGGTCTGACGTTTGGCGACAGA
TGATGTCCGATATTTTCGCATCTGAAGTCGTTGTTCCAAAGAGCTACGAAAGCTCTTGTCTAGGTGCATGTATATTAGGC
CTCTATGCCACAGGAAAAATTGATTCTTTTGAAATCGTTTCCGAAATGGTTGGTAGTACCTACAAACATACACCGAAAGA
AGAAGCAACAAAAGAATACAGACAATTACTGCCTATATTTATTAACCTATCAAGGGCGTTAGAAGATGATTATACACGCA
TTGCAAATTATCAAAGAAATTTAATAAAGTAA

Upstream 100 bases:

>100_bases
CGTACTCGTTTCAAGGAAAAGTATGAAGACTTTGAACGGATTATTAAAAATCATGAGCTTTATATAAAAGCAATCGAATC
AAAAGATCGAGCCCTCATGA

Downstream 100 bases:

>100_bases
AACTTTCATCAGTAATCTCCCACGCCTCGCTTCTATATAAATCTCGAGGTGGGGGCCTTACTGCCCACGAATAGAGGGAT
AAATACAAATACAGCTAAGA

Product: gluconate kinase

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MRPYIKTLMMFKGKSKTSGCRNKCYLKELSKDMSSYMLGIDIGTTSTKAVLFTEKGEVIQTENIGYPLRTPDISTAEQDP
EEIFQAVLQAISNITKQHSDKKTSFISFSSAMHSVIAMDENDQPLTPCITWADNRSEAWAHKIKDELNGHAVYRRTGTPI
HPMSPLSKITWIVNAHPEIAIRTKKYIGIKEYIFKKFFDQYVVDHSIASCMGMMNLKTLDWDEEALKIAGITSAQLSKLV
PTTKIFSNCNPDLAQKIGIDSKTPFVIGASDGVLSNLGVNAIRKGEIAVTIGTSGAIRTIIDKPQTDKKGRIFCYALTEK
HWVIGGPVNNGGMVLRWIRDELASSEVETAKRLGIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPDVRGSFFGL
TMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVTRIQATGGFARSDVWRQMMSDIFASEVVVPKSYESSCLGACILG
LYATGKIDSFEIVSEMVGSTYKHTPKEEATKEYRQLLPIFINLSRALEDDYTRIANYQRNLIK

Sequences:

>Translated_543_residues
MRPYIKTLMMFKGKSKTSGCRNKCYLKELSKDMSSYMLGIDIGTTSTKAVLFTEKGEVIQTENIGYPLRTPDISTAEQDP
EEIFQAVLQAISNITKQHSDKKTSFISFSSAMHSVIAMDENDQPLTPCITWADNRSEAWAHKIKDELNGHAVYRRTGTPI
HPMSPLSKITWIVNAHPEIAIRTKKYIGIKEYIFKKFFDQYVVDHSIASCMGMMNLKTLDWDEEALKIAGITSAQLSKLV
PTTKIFSNCNPDLAQKIGIDSKTPFVIGASDGVLSNLGVNAIRKGEIAVTIGTSGAIRTIIDKPQTDKKGRIFCYALTEK
HWVIGGPVNNGGMVLRWIRDELASSEVETAKRLGIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPDVRGSFFGL
TMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVTRIQATGGFARSDVWRQMMSDIFASEVVVPKSYESSCLGACILG
LYATGKIDSFEIVSEMVGSTYKHTPKEEATKEYRQLLPIFINLSRALEDDYTRIANYQRNLIK
>Mature_543_residues
MRPYIKTLMMFKGKSKTSGCRNKCYLKELSKDMSSYMLGIDIGTTSTKAVLFTEKGEVIQTENIGYPLRTPDISTAEQDP
EEIFQAVLQAISNITKQHSDKKTSFISFSSAMHSVIAMDENDQPLTPCITWADNRSEAWAHKIKDELNGHAVYRRTGTPI
HPMSPLSKITWIVNAHPEIAIRTKKYIGIKEYIFKKFFDQYVVDHSIASCMGMMNLKTLDWDEEALKIAGITSAQLSKLV
PTTKIFSNCNPDLAQKIGIDSKTPFVIGASDGVLSNLGVNAIRKGEIAVTIGTSGAIRTIIDKPQTDKKGRIFCYALTEK
HWVIGGPVNNGGMVLRWIRDELASSEVETAKRLGIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPDVRGSFFGL
TMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVTRIQATGGFARSDVWRQMMSDIFASEVVVPKSYESSCLGACILG
LYATGKIDSFEIVSEMVGSTYKHTPKEEATKEYRQLLPIFINLSRALEDDYTRIANYQRNLIK

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=473, Percent_Identity=22.4101479915433, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI189409120, Length=473, Percent_Identity=22.4101479915433, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4504007, Length=473, Percent_Identity=22.4101479915433, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI41393575, Length=448, Percent_Identity=22.0982142857143, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI18860918, Length=421, Percent_Identity=22.3277909738717, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI88196792, Length=326, Percent_Identity=25.7668711656442, Blast_Score=76, Evalue=1e-13,
Organism=Escherichia coli, GI1789987, Length=499, Percent_Identity=26.6533066132265, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1787789, Length=508, Percent_Identity=24.2125984251968, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1790361, Length=494, Percent_Identity=25.3036437246964, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1790005, Length=521, Percent_Identity=23.8003838771593, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1789168, Length=481, Percent_Identity=20.7900207900208, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789138, Length=510, Percent_Identity=23.1372549019608, Blast_Score=96, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17535599, Length=463, Percent_Identity=23.110151187905, Blast_Score=104, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321755, Length=418, Percent_Identity=25.3588516746411, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17864214, Length=475, Percent_Identity=24.4210526315789, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24654573, Length=399, Percent_Identity=24.812030075188, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24655555, Length=472, Percent_Identity=23.5169491525424, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24655560, Length=472, Percent_Identity=23.5169491525424, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24655570, Length=472, Percent_Identity=23.5169491525424, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24655574, Length=472, Percent_Identity=23.5169491525424, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24655565, Length=472, Percent_Identity=23.5169491525424, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24656367, Length=499, Percent_Identity=21.0420841683367, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357867, Length=511, Percent_Identity=22.1135029354207, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24656372, Length=302, Percent_Identity=24.1721854304636, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 60631; Mature: 60631

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPYIKTLMMFKGKSKTSGCRNKCYLKELSKDMSSYMLGIDIGTTSTKAVLFTEKGEVIQ
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEECCCCEEE
TENIGYPLRTPDISTAEQDPEEIFQAVLQAISNITKQHSDKKTSFISFSSAMHSVIAMDE
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEECC
NDQPLTPCITWADNRSEAWAHKIKDELNGHAVYRRTGTPIHPMSPLSKITWIVNAHPEIA
CCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHEEEEEECCCCEE
IRTKKYIGIKEYIFKKFFDQYVVDHSIASCMGMMNLKTLDWDEEALKIAGITSAQLSKLV
EEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEECCCHHHHHHHC
PTTKIFSNCNPDLAQKIGIDSKTPFVIGASDGVLSNLGVNAIRKGEIAVTIGTSGAIRTI
CHHHHHHCCCHHHHHHCCCCCCCCEEEECCCCHHHHCCCCCEECCCEEEEECCCCCHHHH
IDKPQTDKKGRIFCYALTEKHWVIGGPVNNGGMVLRWIRDELASSEVETAKRLGIDPYDV
HCCCCCCCCCCEEEEEECCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHH
LTKIAERVRPGADGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYN
HHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
LYTVFLALTECMDGPVTRIQATGGFARSDVWRQMMSDIFASEVVVPKSYESSCLGACILG
HHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCEECCCCCCHHHHHHHHHH
LYATGKIDSFEIVSEMVGSTYKHTPKEEATKEYRQLLPIFINLSRALEDDYTRIANYQRN
HHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIK
HCC
>Mature Secondary Structure
MRPYIKTLMMFKGKSKTSGCRNKCYLKELSKDMSSYMLGIDIGTTSTKAVLFTEKGEVIQ
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEECCCCEEE
TENIGYPLRTPDISTAEQDPEEIFQAVLQAISNITKQHSDKKTSFISFSSAMHSVIAMDE
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEECC
NDQPLTPCITWADNRSEAWAHKIKDELNGHAVYRRTGTPIHPMSPLSKITWIVNAHPEIA
CCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHEEEEEECCCCEE
IRTKKYIGIKEYIFKKFFDQYVVDHSIASCMGMMNLKTLDWDEEALKIAGITSAQLSKLV
EEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEECCCHHHHHHHC
PTTKIFSNCNPDLAQKIGIDSKTPFVIGASDGVLSNLGVNAIRKGEIAVTIGTSGAIRTI
CHHHHHHCCCHHHHHHCCCCCCCCEEEECCCCHHHHCCCCCEECCCEEEEECCCCCHHHH
IDKPQTDKKGRIFCYALTEKHWVIGGPVNNGGMVLRWIRDELASSEVETAKRLGIDPYDV
HCCCCCCCCCCEEEEEECCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHH
LTKIAERVRPGADGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYN
HHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
LYTVFLALTECMDGPVTRIQATGGFARSDVWRQMMSDIFASEVVVPKSYESSCLGACILG
HHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCEECCCCCCHHHHHHHHHH
LYATGKIDSFEIVSEMVGSTYKHTPKEEATKEYRQLLPIFINLSRALEDDYTRIANYQRN
HHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIK
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8535972 [H]