Click here to switch to the map view.

The map label for this gene is dcp [H]

Identifier: 117920034

GI number: 117920034

Start: 1862588

End: 1864735

Strand: Direct

Name: dcp [H]

Synonym: Shewana3_1586

Alternate gene names: 117920034

Gene position: 1862588-1864735 (Clockwise)

Preceding gene: 117920031

Following gene: 117920035

Centisome position: 37.46

GC content: 48.93

Gene sequence:

>2148_bases
ATGCGTAAGTCTGTTATTACTACTGCCGTGGCCGCGGCATTGTTATTGGGCGCTTGCTCAGAAAAACCGGCAGCCAATAC
CGAGGCCGCCAATGCGGTCGCGACGCAAGCTGCTGCATCGACTCAAGCTGATGCAACCAATGTGTTATTGAGTAAGAGTC
CACTGCAGGATCAAGCTCCACAGTTTAATCTGATCAAGAGTTCGGATTATGCCCCCGCGTTTGCGCAGGGCATAAAAGAA
CATGAAGCTGAAATTGCCGCCATTATTGCCAATAAACAGGCGCCCACCTTCGATAATACGATTTTAGCCATGGAAACCTC
GGGTGAGTTGTTAACTCGAGTGTCACGCACCTTCTTCAATCTGGCGGGGTTAATCTCCGACGATGATTTTCAAAAGACCG
AGGCGGATTTAGCGCCTAAGCTATCGGCTCACCGCGATAACATTTACTTAGATCCAAGTTTATTTGCCCGTGTTGAAACC
GTATATCAGCAACGTGCCGGGTTAAATGCCGAAGATAAACGCTTGGTCGAGTTTTATTACGAGCAGTTTGTACGTGCAGG
GGCCAAATTATCCGATGCCGATAAAGCCAAAATGCGAGACTTTAACGCTGAGTTAGCGACCCTTGCGACTGAGTTTTCCC
AAAACAGCTTAAAGTCATTTAAAGACGATGTGATTGTTGTGACCGACAAGGCACAACTGGACGGTCTATCTGACAGCGAA
ATCGCGACCTTAGCGGCCGCAGCGCAGGCAGCGGGTAAAACGGGTTACCTGATTACCTTAGTGAACACGACTCGTCAGCC
TATTTTAGCCAGTTTAAATAACCGCGAACTGCGCCAAAAAGTCTGGGAAACCTCGGCTCACCGCGCCGTTGCCAGTAATG
GCCCTTTAATCGTGAAGATGGCGCAGCTGCGCGCCAAGAAAGCCAATTTACTCGGCTTTGATACTTGGGCAGCCTACGCC
GTGGCCGACCAAATGGCTAAAACGCCAAGCGCCGTGTATGAAATTTTAGATGACTTGGCGCCTAAGGCGTTGGCTCACGC
TAAGGCCGATGCGGCGGATATCCAAGCTGAAATCAAAAAGGCTGGCGGTAATTTTGAATTACAACCTTGGGATTGGGCTT
ATTACGCCGAGAAAGTGCGTCAGCAAAAGTACGCCCTCGATGAGAGCAGCATCAAACCCTACTTTGAATTTAACTCTGTG
CTGAAGGATGGCTTGTTCTTCGCGATGCACAAACTCTACGGCATCAGCGTTAAACCGCGCACCGATTTACCAGTATGGAA
TAGCGATGTCCTCGCCTTTGAGGTTTTCGATAAAGACAACAGCTCTATTGGTCTGTTCTATCTTGACCCTTATGCCCGTG
AAGGTAAGGGCGGCGGCGCTTGGATGGATGAGTTTGTCACTCAAAGCGGCCTGCTAGGCACTAAGCCTGTGGTGTATAAC
GCACTGAATATCCCGAAACCTGCCGACGGTCCAACCTTGATGACCTTCGATGAAGTGACCACTATGTTCCATGAATTTGG
TCATGCGGTGCACGGTTTATTCTCCAAGGTGAAATACCCGAGTGTGGCAGGTACCTCTACCGCGCGCGATTTTGTGGAGT
TTCCGTCTCAAGTTAACGAAGATTGGAACATTGACCCTGCGGTCATTGCCAATTACGCCAAGCACTACCAAACTGGTGAG
CCTATTCCTAAAGCTTTACTCGATAAAATCTTAGCATCGAATAAATTTGGTCAAGGTTTTGATACTGTTGAGTATTTAGC
GGCCGCATTACTGGATATGGAATGGCACTCGATTGGTGCTGACACCCAAAATAAGGATGTGGAACAGTTTGAGCATCAAG
TGTTAGCCAAACACGGCCTCGATTTCGCGCCAATTCCACCGCGTTATAAGTCGAGCTATTTTAGCCATGCCTTCTCGGGT
GGCTATTCTGCCGGTTATTACGCTTACCTGTGGACGGAAGTGTTTGCCGCCGATGCCTTTGCCTATATGGGCCAACATGG
TGGCTTAAAAGCCGAAAACGGCGATAAGTTCCGTGATGCGGTATTGTCTAAAGGCAACAGCGAAGATCTGATGCAGGATT
ACATCCACTTTACCGGTCAAAAACCCACGACCGATGCCTTATTAAAGCGCCGTGGTTTAGTCGATTAA

Upstream 100 bases:

>100_bases
CCCAAAGCATGCGTCAGTTGGAAGAGAAGCCAAAATCCGTTACTCGCACCTTTCACTTAAAAAATATAAAGACAGGGCAG
TAACACTCTAGGGAGTTCCT

Downstream 100 bases:

>100_bases
ACGATTCATTGTAAAAAGGGCCAAAGGCTTGGTAGGGCAACCTATCAAGCCTTTTTTTACGCTATTGTTTTTCGATAATC
TTTACTCTAAAATCCCGCCA

Product: peptidyl-dipeptidase Dcp

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 715; Mature: 715

Protein sequence:

>715_residues
MRKSVITTAVAAALLLGACSEKPAANTEAANAVATQAAASTQADATNVLLSKSPLQDQAPQFNLIKSSDYAPAFAQGIKE
HEAEIAAIIANKQAPTFDNTILAMETSGELLTRVSRTFFNLAGLISDDDFQKTEADLAPKLSAHRDNIYLDPSLFARVET
VYQQRAGLNAEDKRLVEFYYEQFVRAGAKLSDADKAKMRDFNAELATLATEFSQNSLKSFKDDVIVVTDKAQLDGLSDSE
IATLAAAAQAAGKTGYLITLVNTTRQPILASLNNRELRQKVWETSAHRAVASNGPLIVKMAQLRAKKANLLGFDTWAAYA
VADQMAKTPSAVYEILDDLAPKALAHAKADAADIQAEIKKAGGNFELQPWDWAYYAEKVRQQKYALDESSIKPYFEFNSV
LKDGLFFAMHKLYGISVKPRTDLPVWNSDVLAFEVFDKDNSSIGLFYLDPYAREGKGGGAWMDEFVTQSGLLGTKPVVYN
ALNIPKPADGPTLMTFDEVTTMFHEFGHAVHGLFSKVKYPSVAGTSTARDFVEFPSQVNEDWNIDPAVIANYAKHYQTGE
PIPKALLDKILASNKFGQGFDTVEYLAAALLDMEWHSIGADTQNKDVEQFEHQVLAKHGLDFAPIPPRYKSSYFSHAFSG
GYSAGYYAYLWTEVFAADAFAYMGQHGGLKAENGDKFRDAVLSKGNSEDLMQDYIHFTGQKPTTDALLKRRGLVD

Sequences:

>Translated_715_residues
MRKSVITTAVAAALLLGACSEKPAANTEAANAVATQAAASTQADATNVLLSKSPLQDQAPQFNLIKSSDYAPAFAQGIKE
HEAEIAAIIANKQAPTFDNTILAMETSGELLTRVSRTFFNLAGLISDDDFQKTEADLAPKLSAHRDNIYLDPSLFARVET
VYQQRAGLNAEDKRLVEFYYEQFVRAGAKLSDADKAKMRDFNAELATLATEFSQNSLKSFKDDVIVVTDKAQLDGLSDSE
IATLAAAAQAAGKTGYLITLVNTTRQPILASLNNRELRQKVWETSAHRAVASNGPLIVKMAQLRAKKANLLGFDTWAAYA
VADQMAKTPSAVYEILDDLAPKALAHAKADAADIQAEIKKAGGNFELQPWDWAYYAEKVRQQKYALDESSIKPYFEFNSV
LKDGLFFAMHKLYGISVKPRTDLPVWNSDVLAFEVFDKDNSSIGLFYLDPYAREGKGGGAWMDEFVTQSGLLGTKPVVYN
ALNIPKPADGPTLMTFDEVTTMFHEFGHAVHGLFSKVKYPSVAGTSTARDFVEFPSQVNEDWNIDPAVIANYAKHYQTGE
PIPKALLDKILASNKFGQGFDTVEYLAAALLDMEWHSIGADTQNKDVEQFEHQVLAKHGLDFAPIPPRYKSSYFSHAFSG
GYSAGYYAYLWTEVFAADAFAYMGQHGGLKAENGDKFRDAVLSKGNSEDLMQDYIHFTGQKPTTDALLKRRGLVD
>Mature_715_residues
MRKSVITTAVAAALLLGACSEKPAANTEAANAVATQAAASTQADATNVLLSKSPLQDQAPQFNLIKSSDYAPAFAQGIKE
HEAEIAAIIANKQAPTFDNTILAMETSGELLTRVSRTFFNLAGLISDDDFQKTEADLAPKLSAHRDNIYLDPSLFARVET
VYQQRAGLNAEDKRLVEFYYEQFVRAGAKLSDADKAKMRDFNAELATLATEFSQNSLKSFKDDVIVVTDKAQLDGLSDSE
IATLAAAAQAAGKTGYLITLVNTTRQPILASLNNRELRQKVWETSAHRAVASNGPLIVKMAQLRAKKANLLGFDTWAAYA
VADQMAKTPSAVYEILDDLAPKALAHAKADAADIQAEIKKAGGNFELQPWDWAYYAEKVRQQKYALDESSIKPYFEFNSV
LKDGLFFAMHKLYGISVKPRTDLPVWNSDVLAFEVFDKDNSSIGLFYLDPYAREGKGGGAWMDEFVTQSGLLGTKPVVYN
ALNIPKPADGPTLMTFDEVTTMFHEFGHAVHGLFSKVKYPSVAGTSTARDFVEFPSQVNEDWNIDPAVIANYAKHYQTGE
PIPKALLDKILASNKFGQGFDTVEYLAAALLDMEWHSIGADTQNKDVEQFEHQVLAKHGLDFAPIPPRYKSSYFSHAFSG
GYSAGYYAYLWTEVFAADAFAYMGQHGGLKAENGDKFRDAVLSKGNSEDLMQDYIHFTGQKPTTDALLKRRGLVD

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=597, Percent_Identity=30.9882747068677, Blast_Score=251, Evalue=2e-66,
Organism=Homo sapiens, GI14149738, Length=639, Percent_Identity=29.8904538341158, Blast_Score=226, Evalue=6e-59,
Organism=Homo sapiens, GI156105687, Length=417, Percent_Identity=28.2973621103118, Blast_Score=163, Evalue=6e-40,
Organism=Escherichia coli, GI1787819, Length=675, Percent_Identity=46.5185185185185, Blast_Score=613, Evalue=1e-176,
Organism=Escherichia coli, GI1789913, Length=686, Percent_Identity=33.2361516034985, Blast_Score=360, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI32565901, Length=595, Percent_Identity=23.5294117647059, Blast_Score=109, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71999758, Length=575, Percent_Identity=19.8260869565217, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319793, Length=593, Percent_Identity=29.1736930860034, Blast_Score=218, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6322715, Length=639, Percent_Identity=23.0046948356808, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI20129717, Length=395, Percent_Identity=28.8607594936709, Blast_Score=162, Evalue=8e-40,
Organism=Drosophila melanogaster, GI21356111, Length=508, Percent_Identity=25.9842519685039, Blast_Score=151, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 78475; Mature: 78475

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSVITTAVAAALLLGACSEKPAANTEAANAVATQAAASTQADATNVLLSKSPLQDQAP
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHEECCCCCCCCCC
QFNLIKSSDYAPAFAQGIKEHEAEIAAIIANKQAPTFDNTILAMETSGELLTRVSRTFFN
CCEEEECCCCCHHHHHHHHHHHHHEEHEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHH
LAGLISDDDFQKTEADLAPKLSAHRDNIYLDPSLFARVETVYQQRAGLNAEDKRLVEFYY
HHHCCCCCHHHHHHHHHCCCHHCCCCCEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
EQFVRAGAKLSDADKAKMRDFNAELATLATEFSQNSLKSFKDDVIVVTDKAQLDGLSDSE
HHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHCCCCCHH
IATLAAAAQAAGKTGYLITLVNTTRQPILASLNNRELRQKVWETSAHRAVASNGPLIVKM
HHHHHHHHHHCCCCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEH
AQLRAKKANLLGFDTWAAYAVADQMAKTPSAVYEILDDLAPKALAHAKADAADIQAEIKK
HHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AGGNFELQPWDWAYYAEKVRQQKYALDESSIKPYFEFNSVLKDGLFFAMHKLYGISVKPR
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
TDLPVWNSDVLAFEVFDKDNSSIGLFYLDPYAREGKGGGAWMDEFVTQSGLLGTKPVVYN
CCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCHHEE
ALNIPKPADGPTLMTFDEVTTMFHEFGHAVHGLFSKVKYPSVAGTSTARDFVEFPSQVNE
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
DWNIDPAVIANYAKHYQTGEPIPKALLDKILASNKFGQGFDTVEYLAAALLDMEWHSIGA
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCC
DTQNKDVEQFEHQVLAKHGLDFAPIPPRYKSSYFSHAFSGGYSAGYYAYLWTEVFAADAF
CCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AYMGQHGGLKAENGDKFRDAVLSKGNSEDLMQDYIHFTGQKPTTDALLKRRGLVD
HHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MRKSVITTAVAAALLLGACSEKPAANTEAANAVATQAAASTQADATNVLLSKSPLQDQAP
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHEECCCCCCCCCC
QFNLIKSSDYAPAFAQGIKEHEAEIAAIIANKQAPTFDNTILAMETSGELLTRVSRTFFN
CCEEEECCCCCHHHHHHHHHHHHHEEHEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHH
LAGLISDDDFQKTEADLAPKLSAHRDNIYLDPSLFARVETVYQQRAGLNAEDKRLVEFYY
HHHCCCCCHHHHHHHHHCCCHHCCCCCEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
EQFVRAGAKLSDADKAKMRDFNAELATLATEFSQNSLKSFKDDVIVVTDKAQLDGLSDSE
HHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHCCCCCHH
IATLAAAAQAAGKTGYLITLVNTTRQPILASLNNRELRQKVWETSAHRAVASNGPLIVKM
HHHHHHHHHHCCCCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEH
AQLRAKKANLLGFDTWAAYAVADQMAKTPSAVYEILDDLAPKALAHAKADAADIQAEIKK
HHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AGGNFELQPWDWAYYAEKVRQQKYALDESSIKPYFEFNSVLKDGLFFAMHKLYGISVKPR
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
TDLPVWNSDVLAFEVFDKDNSSIGLFYLDPYAREGKGGGAWMDEFVTQSGLLGTKPVVYN
CCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCHHEE
ALNIPKPADGPTLMTFDEVTTMFHEFGHAVHGLFSKVKYPSVAGTSTARDFVEFPSQVNE
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
DWNIDPAVIANYAKHYQTGEPIPKALLDKILASNKFGQGFDTVEYLAAALLDMEWHSIGA
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCC
DTQNKDVEQFEHQVLAKHGLDFAPIPPRYKSSYFSHAFSGGYSAGYYAYLWTEVFAADAF
CCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AYMGQHGGLKAENGDKFRDAVLSKGNSEDLMQDYIHFTGQKPTTDALLKRRGLVD
HHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]