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The map label for this gene is rtn [H]

Identifier: 117919229

GI number: 117919229

Start: 898940

End: 900499

Strand: Direct

Name: rtn [H]

Synonym: Shewana3_0777

Alternate gene names: 117919229

Gene position: 898940-900499 (Clockwise)

Preceding gene: 117919228

Following gene: 117919234

Centisome position: 18.08

GC content: 46.15

Gene sequence:

>1560_bases
ATGCCAAACCGTTCAAATCTTATCCAAACGTCGATGCGTAACTTTGCCTCTCTCTTCGAATTACTCCTAAAAAAGTGGTT
GTTCTTACTGCTGTTACCCGTCGTATTAGCTTTTGTTTTTAGCTATTTTATCGCAGTTTATCTGGCACATAACAAGGCGA
CTGAGATTGGCGAGTTCAACCTAGAGCGTTTAGAGGCCATCTTAAAACTGTCCGATCAGATAGGTGAATATGCCATGAAC
CTAACCGAAGAGGATTGTGGCAAGTTAACTGAATACATGCGTTTTCGGCCTTATTTTCGGGGCGTGTTACTTTTCAATGA
CAAGTCATTTTACTGCTCCTCGACAACCGGGGACCTCAATTTACCCCTAAATACTCTGCTGCCAGTTGATAGACTCAAAG
ATGGTTCGCAACATATAGTGCCGGAAACGCCAGCGCGGCCAGGCGTGCCAGCCATTATCACCACTTTTAAGAATGAACAA
ACGCAATACGGCGCGGTTGTGGTATTCGAAGGCCAATACCTGATTGATAGCTTTATTCAACCCGATGTATTTCCCCGCGC
GGTAAAAACCGTTGTCTTAGGTTTGCATGGTGCGACCTTGCCAGCGGCGCCACAGTTTAGCGGTAATGAAGTGATTACTG
TGTTTGCTGGGGATAAATTTGAGGTCCACCAAGATTTCGTTATCCTGCTGGAGATCTCTAAGGCGCTGTTTTGGCACTTT
TATTGGATTGCCTTTGGCCTGTTATTACCGTTGATTTTCACCTTGTTCGTTTTATCTAGCCTACTGTTCTGGAAGCGTAA
TGGGCGTCATTCGCTAGCCGATGACATAAAAAGTGGTATCGAGAACCAAGAGTTTTTCTTGGTCTACCAACCTGTTGTAA
GTAGTGAAGACGGTAAGGCCAAAGGTGTCGAGGCGTTAGTGCGTTGGCAGCATCCGCAAATGGGCTTAGTTCGTCCCGAT
TTGTTTATTCCCATCGCCGAAGAAAGCCAATTAATCGTGCCGTTGACCAATTATATTTTTGAACGCGCCTTGGCGGATTT
TAGGCAATTGCAGTTAACCTCGGATTTCAGGATTGGCTTTAACGTGGCGCCCGAGCATTTTATCCAAAGCGATATCGAGG
CTAAGTTTCGTTACCTTAGGGATGCGTTTGCCGAAATCGGCGTGCAGCCGCTAATCGAAATCACCGAGCGGCAACTATTA
ACGGTGGATATGTGTGAGCGAATTGCAGCGCTGCGTGAGCTGGGCATTCTCGTGGCGATTGATGATTTCGGCACAGGGCA
AACAACCTTGTCGCTGCTGCAAACCTTTACGCTGGATTACCTTAAAATCGATAAATGCTTTATCGATACCATAGGCCAAG
ATTCGGTGACCTCCCATGTGCTCGATACCATCATCGAACTCTGTCATAAGATGAATTATGTGGCCGTGGCCGAAGGCGTG
GAGACCCAAGAGCAGGCGGACTATTTAATCAGTCGTGATGTGCATTTTTTGCAGGGCTATTTATACGCTAAGCCGATGAA
ATTAAATGAACTGGAACTGTGGCTTAAGGAGCATAACTAG

Upstream 100 bases:

>100_bases
GCTCACAGAAATGTCCTATAGTTTATGCCTCACTCTCTTTATCTATGCTAAATATCCTTGATGCAAAAATTAACAATTTA
CTCGAAAGGGATTTGTTACT

Downstream 100 bases:

>100_bases
TTAATAACCGTCAGGGCAGATATGCCCCTGACGGTCAGTTTTGCGAGGCGAGTATTAGAGGCTGTAGCCTGTTTCTTCAT
GTTCGGAAAGATCGAGGCCA

Product: EAL domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 518

Protein sequence:

>519_residues
MPNRSNLIQTSMRNFASLFELLLKKWLFLLLLPVVLAFVFSYFIAVYLAHNKATEIGEFNLERLEAILKLSDQIGEYAMN
LTEEDCGKLTEYMRFRPYFRGVLLFNDKSFYCSSTTGDLNLPLNTLLPVDRLKDGSQHIVPETPARPGVPAIITTFKNEQ
TQYGAVVVFEGQYLIDSFIQPDVFPRAVKTVVLGLHGATLPAAPQFSGNEVITVFAGDKFEVHQDFVILLEISKALFWHF
YWIAFGLLLPLIFTLFVLSSLLFWKRNGRHSLADDIKSGIENQEFFLVYQPVVSSEDGKAKGVEALVRWQHPQMGLVRPD
LFIPIAEESQLIVPLTNYIFERALADFRQLQLTSDFRIGFNVAPEHFIQSDIEAKFRYLRDAFAEIGVQPLIEITERQLL
TVDMCERIAALRELGILVAIDDFGTGQTTLSLLQTFTLDYLKIDKCFIDTIGQDSVTSHVLDTIIELCHKMNYVAVAEGV
ETQEQADYLISRDVHFLQGYLYAKPMKLNELELWLKEHN

Sequences:

>Translated_519_residues
MPNRSNLIQTSMRNFASLFELLLKKWLFLLLLPVVLAFVFSYFIAVYLAHNKATEIGEFNLERLEAILKLSDQIGEYAMN
LTEEDCGKLTEYMRFRPYFRGVLLFNDKSFYCSSTTGDLNLPLNTLLPVDRLKDGSQHIVPETPARPGVPAIITTFKNEQ
TQYGAVVVFEGQYLIDSFIQPDVFPRAVKTVVLGLHGATLPAAPQFSGNEVITVFAGDKFEVHQDFVILLEISKALFWHF
YWIAFGLLLPLIFTLFVLSSLLFWKRNGRHSLADDIKSGIENQEFFLVYQPVVSSEDGKAKGVEALVRWQHPQMGLVRPD
LFIPIAEESQLIVPLTNYIFERALADFRQLQLTSDFRIGFNVAPEHFIQSDIEAKFRYLRDAFAEIGVQPLIEITERQLL
TVDMCERIAALRELGILVAIDDFGTGQTTLSLLQTFTLDYLKIDKCFIDTIGQDSVTSHVLDTIIELCHKMNYVAVAEGV
ETQEQADYLISRDVHFLQGYLYAKPMKLNELELWLKEHN
>Mature_518_residues
PNRSNLIQTSMRNFASLFELLLKKWLFLLLLPVVLAFVFSYFIAVYLAHNKATEIGEFNLERLEAILKLSDQIGEYAMNL
TEEDCGKLTEYMRFRPYFRGVLLFNDKSFYCSSTTGDLNLPLNTLLPVDRLKDGSQHIVPETPARPGVPAIITTFKNEQT
QYGAVVVFEGQYLIDSFIQPDVFPRAVKTVVLGLHGATLPAAPQFSGNEVITVFAGDKFEVHQDFVILLEISKALFWHFY
WIAFGLLLPLIFTLFVLSSLLFWKRNGRHSLADDIKSGIENQEFFLVYQPVVSSEDGKAKGVEALVRWQHPQMGLVRPDL
FIPIAEESQLIVPLTNYIFERALADFRQLQLTSDFRIGFNVAPEHFIQSDIEAKFRYLRDAFAEIGVQPLIEITERQLLT
VDMCERIAALRELGILVAIDDFGTGQTTLSLLQTFTLDYLKIDKCFIDTIGQDSVTSHVLDTIIELCHKMNYVAVAEGVE
TQEQADYLISRDVHFLQGYLYAKPMKLNELELWLKEHN

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=456, Percent_Identity=32.4561403508772, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI87081980, Length=249, Percent_Identity=45.3815261044177, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI87081845, Length=511, Percent_Identity=28.3757338551859, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1786507, Length=286, Percent_Identity=37.0629370629371, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI1790496, Length=524, Percent_Identity=28.0534351145038, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI87081743, Length=295, Percent_Identity=33.8983050847458, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI87081921, Length=252, Percent_Identity=33.3333333333333, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1787541, Length=255, Percent_Identity=32.156862745098, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1787055, Length=241, Percent_Identity=31.5352697095436, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788849, Length=251, Percent_Identity=29.8804780876494, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI226510982, Length=251, Percent_Identity=31.0756972111554, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI87082096, Length=245, Percent_Identity=26.530612244898, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787410, Length=123, Percent_Identity=34.1463414634146, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 59235; Mature: 59104

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNRSNLIQTSMRNFASLFELLLKKWLFLLLLPVVLAFVFSYFIAVYLAHNKATEIGEFN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LERLEAILKLSDQIGEYAMNLTEEDCGKLTEYMRFRPYFRGVLLFNDKSFYCSSTTGDLN
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEECCCEEEECCCCCCC
LPLNTLLPVDRLKDGSQHIVPETPARPGVPAIITTFKNEQTQYGAVVVFEGQYLIDSFIQ
CCHHHCCCHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEECHHHHHHHCC
PDVFPRAVKTVVLGLHGATLPAAPQFSGNEVITVFAGDKFEVHQDFVILLEISKALFWHF
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEECCCEEEEHHHHHHHHHHH
YWIAFGLLLPLIFTLFVLSSLLFWKRNGRHSLADDIKSGIENQEFFLVYQPVVSSEDGKA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCCH
KGVEALVRWQHPQMGLVRPDLFIPIAEESQLIVPLTNYIFERALADFRQLQLTSDFRIGF
HHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEECC
NVAPEHFIQSDIEAKFRYLRDAFAEIGVQPLIEITERQLLTVDMCERIAALRELGILVAI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
DDFGTGQTTLSLLQTFTLDYLKIDKCFIDTIGQDSVTSHVLDTIIELCHKMNYVAVAEGV
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEECCC
ETQEQADYLISRDVHFLQGYLYAKPMKLNELELWLKEHN
CHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHEECCC
>Mature Secondary Structure 
PNRSNLIQTSMRNFASLFELLLKKWLFLLLLPVVLAFVFSYFIAVYLAHNKATEIGEFN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LERLEAILKLSDQIGEYAMNLTEEDCGKLTEYMRFRPYFRGVLLFNDKSFYCSSTTGDLN
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEECCCEEEECCCCCCC
LPLNTLLPVDRLKDGSQHIVPETPARPGVPAIITTFKNEQTQYGAVVVFEGQYLIDSFIQ
CCHHHCCCHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEECHHHHHHHCC
PDVFPRAVKTVVLGLHGATLPAAPQFSGNEVITVFAGDKFEVHQDFVILLEISKALFWHF
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEECCCEEEEHHHHHHHHHHH
YWIAFGLLLPLIFTLFVLSSLLFWKRNGRHSLADDIKSGIENQEFFLVYQPVVSSEDGKA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCCH
KGVEALVRWQHPQMGLVRPDLFIPIAEESQLIVPLTNYIFERALADFRQLQLTSDFRIGF
HHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEECC
NVAPEHFIQSDIEAKFRYLRDAFAEIGVQPLIEITERQLLTVDMCERIAALRELGILVAI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
DDFGTGQTTLSLLQTFTLDYLKIDKCFIDTIGQDSVTSHVLDTIIELCHKMNYVAVAEGV
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEECCC
ETQEQADYLISRDVHFLQGYLYAKPMKLNELELWLKEHN
CHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]