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The map label for this gene is rnr [H]

Identifier: 117919149

GI number: 117919149

Start: 812472

End: 814901

Strand: Direct

Name: rnr [H]

Synonym: Shewana3_0697

Alternate gene names: 117919149

Gene position: 812472-814901 (Clockwise)

Preceding gene: 117919148

Following gene: 117919150

Centisome position: 16.34

GC content: 50.41

Gene sequence:

>2430_bases
ATGATCAAAGACCCTCATTTCGAGCGTGAACAGGATAAGTACGAAAACCCTATCCCAAGTCGTGAGTATATTATCGAGTA
CTTACGTTCTCAAAAATCACCTATTACCCGTGACAGCATCGCTGTTGCACTGCAGATCCATGATGAAGAACAGTTAGAAG
CCCTGCGTCGCCGTTTACGGGCGATGGAGCGCGATGGTGAACTGGTATTTACCCGCGGTCAAAGCTACGGCTTACCTGAA
AAAATGGATCTGATTTCCGGCACTGTCCTTGGGCACAGAGAAGGCTACGGCTTCTTTAAACCTGACGAAGGTGGCGACGA
TTTATTTATCTCAAATCGCGACATGCTGATGTATTTCCATGGCGATAAAGTACTGGCACAAAAAGCTGGTATGGACCGTA
AAGGCCGCCGCGAGGCCCGTATCGTCCGTCTGATCCAACCGCGCAGTGCCGCCATTGTGGGGCGATTCCATGTCGATAGC
GGCATGGCATTTGTGATTGCCGATGATAAGCGCATTACCCAAGAAATCTTAATCGCTACCGAAGATCGCAATGGCGCCCG
TCAAGGCGATGTGGTCGTGGTTGAACTGACCCGTCGTCCGGGTCGATTCGTTAAAGCGGCTGGTAAAGTCACTGAGGTGC
TCGGCAAACAAATGGCGCCAGGAATGGAAATCGAAATTGCCCTGCGTAATTACGATTTACCCCACACTTGGTCGGCTGTG
ATTGAGAAAAAACTGCGCCGGATCCCTGATGAAGTGACTGAAGCCGATAAGGTTGGCCGCGTCGATCTGCGAGACCTGCC
CTTAGTGACTATCGATGGCGAAGATGCCCGCGACTTTGACGATGCAGTATACGCCGAAGTCAAACCCAGTGGTGGATGGC
GTCTATGGGTGGCGATTGCGGATGTGAGCTACTACGTGCGTACCGATTCGGCCTTAGATACCGAAGCCCGTGCCCGTGGT
AACTCGGTATACTTCCCATCGCAAGTGATCCCTATGCTGCCGGAGAAAATCTCTAACGGCCTGTGCTCGCTCAATCCCCA
TGTCGACCGCCTGTGTATGGTCGCTGAGATGACGATTTCGGCACGCGGTAAGCTGTCGGGTTATAAGTTTTATCCCGCAG
TGATGCATTCACATGCGCGTTTCACTTACACCCAAGTAGCTGCCATGCTCGAAGGCGGACCGATTGCGCCTGAGCATGAA
GCGCTATTCCCGCATCTGCAATGTTTGCAGTCGCTTTATTTGGCGCTCGATGAACAGCGCGCCGAGCGTGGGGCGATTGC
CTTTGAGACCCTAGAAACGCAGTTTATTTTTAACGACCAGCGCAAGATCGATAAGATTGTGCCAAGAGCGCGTAATCAAG
CTCATAAAATCATTGAAGAATGTATGATTTTGGCCAACGTATCGGCCGCTAAGTTTGTGAAAAAGCACAAGGGTGAAATC
CTCTATCGCGTGCATGAATCGCCCTCTGAGCAGAAGCTCGCAAACTTTAAAGAGTTTCTGGCCGAACGAGGTTTAAGCAT
GGGCGGCGGACTCGAGCCAACACCTGCGGATTACCAGAATGTGATGCTGCAAATCGCCGATAGGCCCGATGCCGAGCTTA
TCCAAGTGATGTTACTGCGCTCAATGCGCCAAGCTATCTACACACCTGATAACGAAGGCCACTTTGGTTTAGCACTCGAA
GAATATGCGCACTTCACTTCGCCAATTCGTCGTTATCCTGACTTAGTGCTTCACCGCGTGATCCGCTATTTATTGGCGAA
GGAAAAAGGTGAAGCCAATGAGAAGTGGACATCCGATGGTGGCTACCATTATCAACTCGATGAGTTAGACCTTTTAGGCG
AAGAATGTTCGAACACCGAGCGCCGTGCCGATGAAGCGACCCGTGATGTAAGCGACTGGTTGAAATGTGAATTTATGCAG
GACCATGTAGGTGACACCTTCGAGGCGGTTATTGCCTCTGTCACTAACTTTGGTTTATTCGTTCGCTTAAATGACTTATT
TATCGATGGCTTAGTACATATTTCTAGTTTGGGCAGCGATTATTATCAGTTCGACCCTATGCGTCAGCGTTTGATTGGCG
AGCATACAGGTCAAATCTATCAAGTGGGTGACCCCGTCACGGTAAAAGTGGCTGCGGTAAACTTGGATGATAGACAGATT
GACTTAGTCATGCTTGGCGATAGCGGAAAAGGCGGTCGCCGTAAGTCTGCGCCGAGTCGAGAAAAACCGATGACAGCGCG
TGAGCGGGTAAACCGTGAAGGCGCAAAAATGGCTAAGGCAGCTAAATCGACAGGTGCGAAATCGAAAGCCGGTTCAGATA
AAGCTGGGGCGAGTAAGTCCAAGTCTAAAGCAGGCGCTAAACCTAAGAAAAGCGTAAAAAATTCGGCGAAAAAGCCAAAG
GCCGCGAAGCGGAGCACGAGAAAGAAGTAA

Upstream 100 bases:

>100_bases
CGCTAAAATGCCCGCCAGTGCAGTGGCGCGGGCCCAGCAAGAGCACTTGCGAACCCGTTGAGTTGTCTCTACAGATTGAG
ACAGAAATATTGGATATTGA

Downstream 100 bases:

>100_bases
ATGAAAAAACAAGATATTATTTTTGGGATCCACGCGGTTGAAGCGCTGTTAAAACACAGCCCTGAGCGCATTATTGAACT
TTGGCTGCTGCAGGGCCGTG

Product: RNAse R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 809; Mature: 809

Protein sequence:

>809_residues
MIKDPHFEREQDKYENPIPSREYIIEYLRSQKSPITRDSIAVALQIHDEEQLEALRRRLRAMERDGELVFTRGQSYGLPE
KMDLISGTVLGHREGYGFFKPDEGGDDLFISNRDMLMYFHGDKVLAQKAGMDRKGRREARIVRLIQPRSAAIVGRFHVDS
GMAFVIADDKRITQEILIATEDRNGARQGDVVVVELTRRPGRFVKAAGKVTEVLGKQMAPGMEIEIALRNYDLPHTWSAV
IEKKLRRIPDEVTEADKVGRVDLRDLPLVTIDGEDARDFDDAVYAEVKPSGGWRLWVAIADVSYYVRTDSALDTEARARG
NSVYFPSQVIPMLPEKISNGLCSLNPHVDRLCMVAEMTISARGKLSGYKFYPAVMHSHARFTYTQVAAMLEGGPIAPEHE
ALFPHLQCLQSLYLALDEQRAERGAIAFETLETQFIFNDQRKIDKIVPRARNQAHKIIEECMILANVSAAKFVKKHKGEI
LYRVHESPSEQKLANFKEFLAERGLSMGGGLEPTPADYQNVMLQIADRPDAELIQVMLLRSMRQAIYTPDNEGHFGLALE
EYAHFTSPIRRYPDLVLHRVIRYLLAKEKGEANEKWTSDGGYHYQLDELDLLGEECSNTERRADEATRDVSDWLKCEFMQ
DHVGDTFEAVIASVTNFGLFVRLNDLFIDGLVHISSLGSDYYQFDPMRQRLIGEHTGQIYQVGDPVTVKVAAVNLDDRQI
DLVMLGDSGKGGRRKSAPSREKPMTARERVNREGAKMAKAAKSTGAKSKAGSDKAGASKSKSKAGAKPKKSVKNSAKKPK
AAKRSTRKK

Sequences:

>Translated_809_residues
MIKDPHFEREQDKYENPIPSREYIIEYLRSQKSPITRDSIAVALQIHDEEQLEALRRRLRAMERDGELVFTRGQSYGLPE
KMDLISGTVLGHREGYGFFKPDEGGDDLFISNRDMLMYFHGDKVLAQKAGMDRKGRREARIVRLIQPRSAAIVGRFHVDS
GMAFVIADDKRITQEILIATEDRNGARQGDVVVVELTRRPGRFVKAAGKVTEVLGKQMAPGMEIEIALRNYDLPHTWSAV
IEKKLRRIPDEVTEADKVGRVDLRDLPLVTIDGEDARDFDDAVYAEVKPSGGWRLWVAIADVSYYVRTDSALDTEARARG
NSVYFPSQVIPMLPEKISNGLCSLNPHVDRLCMVAEMTISARGKLSGYKFYPAVMHSHARFTYTQVAAMLEGGPIAPEHE
ALFPHLQCLQSLYLALDEQRAERGAIAFETLETQFIFNDQRKIDKIVPRARNQAHKIIEECMILANVSAAKFVKKHKGEI
LYRVHESPSEQKLANFKEFLAERGLSMGGGLEPTPADYQNVMLQIADRPDAELIQVMLLRSMRQAIYTPDNEGHFGLALE
EYAHFTSPIRRYPDLVLHRVIRYLLAKEKGEANEKWTSDGGYHYQLDELDLLGEECSNTERRADEATRDVSDWLKCEFMQ
DHVGDTFEAVIASVTNFGLFVRLNDLFIDGLVHISSLGSDYYQFDPMRQRLIGEHTGQIYQVGDPVTVKVAAVNLDDRQI
DLVMLGDSGKGGRRKSAPSREKPMTARERVNREGAKMAKAAKSTGAKSKAGSDKAGASKSKSKAGAKPKKSVKNSAKKPK
AAKRSTRKK
>Mature_809_residues
MIKDPHFEREQDKYENPIPSREYIIEYLRSQKSPITRDSIAVALQIHDEEQLEALRRRLRAMERDGELVFTRGQSYGLPE
KMDLISGTVLGHREGYGFFKPDEGGDDLFISNRDMLMYFHGDKVLAQKAGMDRKGRREARIVRLIQPRSAAIVGRFHVDS
GMAFVIADDKRITQEILIATEDRNGARQGDVVVVELTRRPGRFVKAAGKVTEVLGKQMAPGMEIEIALRNYDLPHTWSAV
IEKKLRRIPDEVTEADKVGRVDLRDLPLVTIDGEDARDFDDAVYAEVKPSGGWRLWVAIADVSYYVRTDSALDTEARARG
NSVYFPSQVIPMLPEKISNGLCSLNPHVDRLCMVAEMTISARGKLSGYKFYPAVMHSHARFTYTQVAAMLEGGPIAPEHE
ALFPHLQCLQSLYLALDEQRAERGAIAFETLETQFIFNDQRKIDKIVPRARNQAHKIIEECMILANVSAAKFVKKHKGEI
LYRVHESPSEQKLANFKEFLAERGLSMGGGLEPTPADYQNVMLQIADRPDAELIQVMLLRSMRQAIYTPDNEGHFGLALE
EYAHFTSPIRRYPDLVLHRVIRYLLAKEKGEANEKWTSDGGYHYQLDELDLLGEECSNTERRADEATRDVSDWLKCEFMQ
DHVGDTFEAVIASVTNFGLFVRLNDLFIDGLVHISSLGSDYYQFDPMRQRLIGEHTGQIYQVGDPVTVKVAAVNLDDRQI
DLVMLGDSGKGGRRKSAPSREKPMTARERVNREGAKMAKAAKSTGAKSKAGSDKAGASKSKSKAGAKPKKSVKNSAKKPK
AAKRSTRKK

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=433, Percent_Identity=31.1778290993072, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI190014625, Length=433, Percent_Identity=31.1778290993072, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI134288890, Length=408, Percent_Identity=30.1470588235294, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI19115966, Length=508, Percent_Identity=25.3937007874016, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI219521928, Length=508, Percent_Identity=25.3937007874016, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI156105695, Length=315, Percent_Identity=26.031746031746, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI156105693, Length=315, Percent_Identity=26.031746031746, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI87082383, Length=726, Percent_Identity=60.4683195592286, Blast_Score=927, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=645, Percent_Identity=28.062015503876, Blast_Score=188, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI212645896, Length=434, Percent_Identity=29.2626728110599, Blast_Score=162, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17553506, Length=416, Percent_Identity=29.8076923076923, Blast_Score=150, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6324552, Length=558, Percent_Identity=26.5232974910394, Blast_Score=161, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6320499, Length=398, Percent_Identity=22.3618090452261, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24649634, Length=436, Percent_Identity=28.2110091743119, Blast_Score=165, Evalue=1e-40,
Organism=Drosophila melanogaster, GI19922976, Length=360, Percent_Identity=27.2222222222222, Blast_Score=125, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24654597, Length=360, Percent_Identity=27.2222222222222, Blast_Score=125, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24654592, Length=360, Percent_Identity=27.2222222222222, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 91043; Mature: 91043

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKDPHFEREQDKYENPIPSREYIIEYLRSQKSPITRDSIAVALQIHDEEQLEALRRRLR
CCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHH
AMERDGELVFTRGQSYGLPEKMDLISGTVLGHREGYGFFKPDEGGDDLFISNRDMLMYFH
HHCCCCCEEEECCCCCCCCHHHHHHHCEEEECCCCCCCCCCCCCCCEEEEECCCEEEEEC
GDKVLAQKAGMDRKGRREARIVRLIQPRSAAIVGRFHVDSGMAFVIADDKRITQEILIAT
CCHHHHHHCCCCCCCCHHHHHHEEECCCCCEEEEEEEECCCCEEEEECCHHHCEEHEEEE
EDRNGARQGDVVVVELTRRPGRFVKAAGKVTEVLGKQMAPGMEIEIALRNYDLPHTWSAV
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHH
IEKKLRRIPDEVTEADKVGRVDLRDLPLVTIDGEDARDFDDAVYAEVKPSGGWRLWVAIA
HHHHHHHCCHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCEEEEEEE
DVSYYVRTDSALDTEARARGNSVYFPSQVIPMLPEKISNGLCSLNPHVDRLCMVAEMTIS
EEEEEEECCCCCCCHHHHCCCCEECCHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHH
ARGKLSGYKFYPAVMHSHARFTYTQVAAMLEGGPIAPEHEALFPHLQCLQSLYLALDEQR
CCCCCCCEEECHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AERGAIAFETLETQFIFNDQRKIDKIVPRARNQAHKIIEECMILANVSAAKFVKKHKGEI
HHCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCE
LYRVHESPSEQKLANFKEFLAERGLSMGGGLEPTPADYQNVMLQIADRPDAELIQVMLLR
EEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHEEECCCCCHHHHHHHHHH
SMRQAIYTPDNEGHFGLALEEYAHFTSPIRRYPDLVLHRVIRYLLAKEKGEANEKWTSDG
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GYHYQLDELDLLGEECSNTERRADEATRDVSDWLKCEFMQDHVGDTFEAVIASVTNFGLF
CEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEE
VRLNDLFIDGLVHISSLGSDYYQFDPMRQRLIGEHTGQIYQVGDPVTVKVAAVNLDDRQI
EEEHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHCCCCEEECCCCEEEEEEEEECCCCEE
DLVMLGDSGKGGRRKSAPSREKPMTARERVNREGAKMAKAAKSTGAKSKAGSDKAGASKS
EEEEECCCCCCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
KSKAGAKPKKSVKNSAKKPKAAKRSTRKK
HHHCCCCCHHHHHHHHCCCCHHHHHCCCC
>Mature Secondary Structure
MIKDPHFEREQDKYENPIPSREYIIEYLRSQKSPITRDSIAVALQIHDEEQLEALRRRLR
CCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHH
AMERDGELVFTRGQSYGLPEKMDLISGTVLGHREGYGFFKPDEGGDDLFISNRDMLMYFH
HHCCCCCEEEECCCCCCCCHHHHHHHCEEEECCCCCCCCCCCCCCCEEEEECCCEEEEEC
GDKVLAQKAGMDRKGRREARIVRLIQPRSAAIVGRFHVDSGMAFVIADDKRITQEILIAT
CCHHHHHHCCCCCCCCHHHHHHEEECCCCCEEEEEEEECCCCEEEEECCHHHCEEHEEEE
EDRNGARQGDVVVVELTRRPGRFVKAAGKVTEVLGKQMAPGMEIEIALRNYDLPHTWSAV
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHH
IEKKLRRIPDEVTEADKVGRVDLRDLPLVTIDGEDARDFDDAVYAEVKPSGGWRLWVAIA
HHHHHHHCCHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCEEEEEEE
DVSYYVRTDSALDTEARARGNSVYFPSQVIPMLPEKISNGLCSLNPHVDRLCMVAEMTIS
EEEEEEECCCCCCCHHHHCCCCEECCHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHH
ARGKLSGYKFYPAVMHSHARFTYTQVAAMLEGGPIAPEHEALFPHLQCLQSLYLALDEQR
CCCCCCCEEECHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AERGAIAFETLETQFIFNDQRKIDKIVPRARNQAHKIIEECMILANVSAAKFVKKHKGEI
HHCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCE
LYRVHESPSEQKLANFKEFLAERGLSMGGGLEPTPADYQNVMLQIADRPDAELIQVMLLR
EEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHEEECCCCCHHHHHHHHHH
SMRQAIYTPDNEGHFGLALEEYAHFTSPIRRYPDLVLHRVIRYLLAKEKGEANEKWTSDG
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GYHYQLDELDLLGEECSNTERRADEATRDVSDWLKCEFMQDHVGDTFEAVIASVTNFGLF
CEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEE
VRLNDLFIDGLVHISSLGSDYYQFDPMRQRLIGEHTGQIYQVGDPVTVKVAAVNLDDRQI
EEEHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHCCCCEEECCCCEEEEEEEEECCCCEE
DLVMLGDSGKGGRRKSAPSREKPMTARERVNREGAKMAKAAKSTGAKSKAGSDKAGASKS
EEEEECCCCCCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
KSKAGAKPKKSVKNSAKKPKAAKRSTRKK
HHHCCCCCHHHHHHHHCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]