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The map label for this gene is plsC [H]

Identifier: 117919021

GI number: 117919021

Start: 661022

End: 661804

Strand: Direct

Name: plsC [H]

Synonym: Shewana3_0568

Alternate gene names: 117919021

Gene position: 661022-661804 (Clockwise)

Preceding gene: 117919020

Following gene: 117919022

Centisome position: 13.29

GC content: 47.77

Gene sequence:

>783_bases
GTGGCTATACTGTCGCCACTTTCATCCTTGGAGTATGTCGTGCTGTTACTCGTCAGATCTGTGTTGTTGGCTGTGTCATT
GTTACTCGCGTTTATTTTTGGTGGGTTGGTCTGCTTGTTGCGGCCCCGTCACCGTGACAATGTACATATGTTCGCCAAGA
TCTTCTCATCCGTCGCCCCTATTCTAGGGCTTAAAGTCATAGTGCGTCGGCATAAAGAAATTCAGGATGGCCCTTATATC
TTTTTAGGGAACCATCAAAATAACTTCGATCTGTTCACTCATACTAAAGCCGTGCCGAAAAGCACCGTCAGCTTAGGCAA
AAAGAGCTTAGTGTGGATCCCGCTATTCGGGCAGATCTACTGGTTATCGGGCAATATTCTGATCGATAGAAAAAATCGCA
ACAGTGCCTTCGATACCATGGCTAAAACCGCCGAAAAGATTAAACAGAACCGTTTATCTGTGTGGATTTTCCCCGAGGGT
ACCCGCTCACGTGGCCGCGGTTTGCTCCCCTTTAAGGCTGGCGCCTTCCATACGGCGATTGCCGCAGGGGTGCCGATAGT
GCCAGTGCTTGCCTCTTGTCAGAGCCATATTAATTTAAACCGTTGGGATAACGGGGTGGTGATCATTGAGATGATGGCGC
CTATCCCGACCGAAGGGTTAGATAAAGCCGATGTGAAGGCCTTTTCTGCTCAAGTGTATGAGACTATGTCAGCCAAATTT
AACGAGATAAATCGTGAAGCGGCAACATTAATGGGTAAAACTCTCGAAGGCGATGACGTATAA

Upstream 100 bases:

>100_bases
CATCGTCGTGCATGATTGCGCGAGTACCGATGGGCTTTTGTTTGGATTGTTAGCAACTCAGCTTACAGATGTAAACATTA
TATTGAGTCCCTAGGGCTGG

Downstream 100 bases:

>100_bases
TAGCGCCAATTTGAGCCAGTTTTACCTTAACGGAGACAAATCCATGTCTATTGAAAGTCAATTAAAAGCCCAACTTGCCG
AGAATCGTGACATAGTGCAA

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MAILSPLSSLEYVVLLLVRSVLLAVSLLLAFIFGGLVCLLRPRHRDNVHMFAKIFSSVAPILGLKVIVRRHKEIQDGPYI
FLGNHQNNFDLFTHTKAVPKSTVSLGKKSLVWIPLFGQIYWLSGNILIDRKNRNSAFDTMAKTAEKIKQNRLSVWIFPEG
TRSRGRGLLPFKAGAFHTAIAAGVPIVPVLASCQSHINLNRWDNGVVIIEMMAPIPTEGLDKADVKAFSAQVYETMSAKF
NEINREAATLMGKTLEGDDV

Sequences:

>Translated_260_residues
MAILSPLSSLEYVVLLLVRSVLLAVSLLLAFIFGGLVCLLRPRHRDNVHMFAKIFSSVAPILGLKVIVRRHKEIQDGPYI
FLGNHQNNFDLFTHTKAVPKSTVSLGKKSLVWIPLFGQIYWLSGNILIDRKNRNSAFDTMAKTAEKIKQNRLSVWIFPEG
TRSRGRGLLPFKAGAFHTAIAAGVPIVPVLASCQSHINLNRWDNGVVIIEMMAPIPTEGLDKADVKAFSAQVYETMSAKF
NEINREAATLMGKTLEGDDV
>Mature_259_residues
AILSPLSSLEYVVLLLVRSVLLAVSLLLAFIFGGLVCLLRPRHRDNVHMFAKIFSSVAPILGLKVIVRRHKEIQDGPYIF
LGNHQNNFDLFTHTKAVPKSTVSLGKKSLVWIPLFGQIYWLSGNILIDRKNRNSAFDTMAKTAEKIKQNRLSVWIFPEGT
RSRGRGLLPFKAGAFHTAIAAGVPIVPVLASCQSHINLNRWDNGVVIIEMMAPIPTEGLDKADVKAFSAQVYETMSAKFN
EINREAATLMGKTLEGDDV

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=215, Percent_Identity=34.4186046511628, Blast_Score=141, Evalue=5e-34,
Organism=Homo sapiens, GI15100175, Length=215, Percent_Identity=34.4186046511628, Blast_Score=141, Evalue=5e-34,
Organism=Homo sapiens, GI6041665, Length=232, Percent_Identity=34.051724137931, Blast_Score=131, Evalue=6e-31,
Organism=Escherichia coli, GI1789395, Length=237, Percent_Identity=47.6793248945148, Blast_Score=238, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17564032, Length=204, Percent_Identity=34.8039215686275, Blast_Score=127, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17568319, Length=255, Percent_Identity=30.9803921568627, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320151, Length=243, Percent_Identity=34.5679012345679, Blast_Score=140, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281364648, Length=269, Percent_Identity=27.8810408921933, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24582856, Length=269, Percent_Identity=27.8810408921933, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24582854, Length=269, Percent_Identity=27.8810408921933, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24641614, Length=216, Percent_Identity=32.8703703703704, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24641612, Length=216, Percent_Identity=32.8703703703704, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28823; Mature: 28692

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILSPLSSLEYVVLLLVRSVLLAVSLLLAFIFGGLVCLLRPRHRDNVHMFAKIFSSVAP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
ILGLKVIVRRHKEIQDGPYIFLGNHQNNFDLFTHTKAVPKSTVSLGKKSLVWIPLFGQIY
HHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCCCHHHHHCCCCCEEEEEECCEEE
WLSGNILIDRKNRNSAFDTMAKTAEKIKQNRLSVWIFPEGTRSRGRGLLPFKAGAFHTAI
EEECCEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHH
AAGVPIVPVLASCQSHINLNRWDNGVVIIEMMAPIPTEGLDKADVKAFSAQVYETMSAKF
HCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
NEINREAATLMGKTLEGDDV
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AILSPLSSLEYVVLLLVRSVLLAVSLLLAFIFGGLVCLLRPRHRDNVHMFAKIFSSVAP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
ILGLKVIVRRHKEIQDGPYIFLGNHQNNFDLFTHTKAVPKSTVSLGKKSLVWIPLFGQIY
HHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCCCHHHHHCCCCCEEEEEECCEEE
WLSGNILIDRKNRNSAFDTMAKTAEKIKQNRLSVWIFPEGTRSRGRGLLPFKAGAFHTAI
EEECCEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHH
AAGVPIVPVLASCQSHINLNRWDNGVVIIEMMAPIPTEGLDKADVKAFSAQVYETMSAKF
HCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
NEINREAATLMGKTLEGDDV
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1557036; 9278503 [H]