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The map label for this gene is 117918991

Identifier: 117918991

GI number: 117918991

Start: 631159

End: 632601

Strand: Direct

Name: 117918991

Synonym: Shewana3_0537

Alternate gene names: NA

Gene position: 631159-632601 (Clockwise)

Preceding gene: 117918990

Following gene: 117918992

Centisome position: 12.69

GC content: 50.66

Gene sequence:

>1443_bases
ATGCAGATGACATTGCAGTTTTTGGGCGCGACCGAGGAAGTGACTGGCTCGTGCCACTTACTCACAGTGGCAGGTAAGCA
AATGCTGCTCGATTGCGGCCTCATTCAAGGCGGCAAGGCCGATGAGTTACGTAATCACGAACCTTTTAGCTTCGATCCCC
TTGCTATTTCAGCCGTTGTCTTGAGTCACGCCCATATTGATCATTCGGGCCGTTTACCTCTGTTGGTTAAGGCGGGTTAT
ACCGGGCCGATTTTTACCCATAAAGCGACGGCTGAACTGTGTGCCATCATGCTGAAAGATGCCGCCATGTTGCAGGTGCG
CGATACCGAAAGAACCAATAAGAAGCGTGCGAAGCATGAGTTGGACCCCCTAGAACCGCTATTTACCGTGGAAGATGCGG
AGCAGGCCATTACTCAGTTTGTGTCGCTGGAATATGGCCAAGTCACCCGGGTTATTCCCCATGTGGATATTTGCTTATCG
GATGCGGGGCATATTTTAGGCTCGGCACTGGTGGAGCTTTGGTTAGGTGAGGGGAAAGCGCAGAAAAAACTGGTATTTAG
TGGCGATCTTGGCCGTGCTGGCATGCCGATATTACGTAATCCCACCTTAGTCGACACCGCCGATTTAGTGTTAATGGAAA
GCACCTACGGTAATCGCTTTCACCGCAGCTGGACCGATACGCTTGCCGAGTTAAAGGCGATTTTCGCCAAGGCGGTGACC
GAGAGCCACGGCAATATTCTGTTGCCAGCGTTCTCTGTTGGGCGTGCGCAGGAGCTCTTATATCTATTTCATTTATATGC
CAAAGAGTGGGATCTCTCCCGCTGGAAAGTCTGCCTCGATAGTCCTATGGCGATTGAGGCGACGCGGGTGTATGTCAATA
ACTACCCCTTAATGGATGATGATTTTAAGCGCTTTACGCGCCAGCATCCGGGGCAACATCCGTTATTGTCTAATGTAGAA
TTTATCCAAACGACTGAGGAGTCTATCGCCCTTAACGATGTGCACAAAGGATTGATCATTATTGCGGGCAGCGGCATGTG
TAACGGTGGCCGCATCCGCAGTCATTTAGAGCACAATCTATGGCGTCCAGAATGTGATGTGATTATCTGCGGCTATCAAG
CACTTGGTACGCCGGGACGTGCCTTAGTCGATGGCGTCGAGGAGCTGACTATCCATGGTAATAGCATTAAAGTTGCCGCT
AAATTGCATACTGTCGGTGGCTTATCGGCCCATGCGGATCAGGCGGAGTTATTACGTTGGTATCGACATTTTGAATCGCA
GCCGCCCCTGGTGCTTGTTCACGGCGAACCCGAAGCGCAGCAGGGATTAGTCGCTGTGATGAATCAAGACTCGAAAACCA
AACCTAAAGCGCTGGCTATTGCCACCCGTGGCGATATGTTGGATTTAAATGCCTTACCCAAATTAGTTTGGGTGACTAAC
TAG

Upstream 100 bases:

>100_bases
GAAAGTTGGCTTTGATCATGCTTTACCAATTATTCCTTTTTCTTTTAGGAATAAGGGCATAGTCTATCTTTAAAAGAGAT
AAACATGCTGGAGGCAAGCT

Downstream 100 bases:

>100_bases
CTAAGATAACTTAATTAGCTAATTTTGCTGCATTATTGACATTGAATTATGCTTGGATTACACCTTTAAACACTTTTACT
CATGGCTATCGTATCTCGCT

Product: aspartate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MQMTLQFLGATEEVTGSCHLLTVAGKQMLLDCGLIQGGKADELRNHEPFSFDPLAISAVVLSHAHIDHSGRLPLLVKAGY
TGPIFTHKATAELCAIMLKDAAMLQVRDTERTNKKRAKHELDPLEPLFTVEDAEQAITQFVSLEYGQVTRVIPHVDICLS
DAGHILGSALVELWLGEGKAQKKLVFSGDLGRAGMPILRNPTLVDTADLVLMESTYGNRFHRSWTDTLAELKAIFAKAVT
ESHGNILLPAFSVGRAQELLYLFHLYAKEWDLSRWKVCLDSPMAIEATRVYVNNYPLMDDDFKRFTRQHPGQHPLLSNVE
FIQTTEESIALNDVHKGLIIIAGSGMCNGGRIRSHLEHNLWRPECDVIICGYQALGTPGRALVDGVEELTIHGNSIKVAA
KLHTVGGLSAHADQAELLRWYRHFESQPPLVLVHGEPEAQQGLVAVMNQDSKTKPKALAIATRGDMLDLNALPKLVWVTN

Sequences:

>Translated_480_residues
MQMTLQFLGATEEVTGSCHLLTVAGKQMLLDCGLIQGGKADELRNHEPFSFDPLAISAVVLSHAHIDHSGRLPLLVKAGY
TGPIFTHKATAELCAIMLKDAAMLQVRDTERTNKKRAKHELDPLEPLFTVEDAEQAITQFVSLEYGQVTRVIPHVDICLS
DAGHILGSALVELWLGEGKAQKKLVFSGDLGRAGMPILRNPTLVDTADLVLMESTYGNRFHRSWTDTLAELKAIFAKAVT
ESHGNILLPAFSVGRAQELLYLFHLYAKEWDLSRWKVCLDSPMAIEATRVYVNNYPLMDDDFKRFTRQHPGQHPLLSNVE
FIQTTEESIALNDVHKGLIIIAGSGMCNGGRIRSHLEHNLWRPECDVIICGYQALGTPGRALVDGVEELTIHGNSIKVAA
KLHTVGGLSAHADQAELLRWYRHFESQPPLVLVHGEPEAQQGLVAVMNQDSKTKPKALAIATRGDMLDLNALPKLVWVTN
>Mature_480_residues
MQMTLQFLGATEEVTGSCHLLTVAGKQMLLDCGLIQGGKADELRNHEPFSFDPLAISAVVLSHAHIDHSGRLPLLVKAGY
TGPIFTHKATAELCAIMLKDAAMLQVRDTERTNKKRAKHELDPLEPLFTVEDAEQAITQFVSLEYGQVTRVIPHVDICLS
DAGHILGSALVELWLGEGKAQKKLVFSGDLGRAGMPILRNPTLVDTADLVLMESTYGNRFHRSWTDTLAELKAIFAKAVT
ESHGNILLPAFSVGRAQELLYLFHLYAKEWDLSRWKVCLDSPMAIEATRVYVNNYPLMDDDFKRFTRQHPGQHPLLSNVE
FIQTTEESIALNDVHKGLIIIAGSGMCNGGRIRSHLEHNLWRPECDVIICGYQALGTPGRALVDGVEELTIHGNSIKVAA
KLHTVGGLSAHADQAELLRWYRHFESQPPLVLVHGEPEAQQGLVAVMNQDSKTKPKALAIATRGDMLDLNALPKLVWVTN

Specific function: Has endoribonuclease activity towards 23S and 16S rRNA (in vitro) [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family [H]

Homologues:

Organism=Homo sapiens, GI33300633, Length=461, Percent_Identity=25.3796095444685, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI7706427, Length=464, Percent_Identity=26.2931034482759, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32564696, Length=497, Percent_Identity=25.9557344064386, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI32566029, Length=452, Percent_Identity=26.9911504424779, Blast_Score=105, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6323307, Length=453, Percent_Identity=26.0485651214128, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24648013, Length=445, Percent_Identity=28.314606741573, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI21358523, Length=451, Percent_Identity=27.2727272727273, Blast_Score=122, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 52982; Mature: 52982

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMTLQFLGATEEVTGSCHLLTVAGKQMLLDCGLIQGGKADELRNHEPFSFDPLAISAVV
CCEEEEECCCCHHCCCCEEEEEECCCHHHHHCCCCCCCCCHHCCCCCCCCCCHHHHHHHH
LSHAHIDHSGRLPLLVKAGYTGPIFTHKATAELCAIMLKDAAMLQVRDTERTNKKRAKHE
HHHHCCCCCCCCCEEEECCCCCCCEECHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHC
LDPLEPLFTVEDAEQAITQFVSLEYGQVTRVIPHVDICLSDAGHILGSALVELWLGEGKA
CCCCCCEEEHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
QKKLVFSGDLGRAGMPILRNPTLVDTADLVLMESTYGNRFHRSWTDTLAELKAIFAKAVT
CCEEEEECCCCCCCCCCCCCCCEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
ESHGNILLPAFSVGRAQELLYLFHLYAKEWDLSRWKVCLDSPMAIEATRVYVNNYPLMDD
CCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEEEEEEECCCCCCH
DFKRFTRQHPGQHPLLSNVEFIQTTEESIALNDVHKGLIIIAGSGMCNGGRIRSHLEHNL
HHHHHHHHCCCCCCCCCCCHHEEECCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCC
WRPECDVIICGYQALGTPGRALVDGVEELTIHGNSIKVAAKLHTVGGLSAHADQAELLRW
CCCCCCEEEECCHHCCCCCHHHHCCCHHEEEECCEEEEEEEEEECCCCCCCCCHHHHHHH
YRHFESQPPLVLVHGEPEAQQGLVAVMNQDSKTKPKALAIATRGDMLDLNALPKLVWVTN
HHHHCCCCCEEEEECCCCHHCCEEEEECCCCCCCCCEEEEEECCCEEECCCCCCEEEECC
>Mature Secondary Structure
MQMTLQFLGATEEVTGSCHLLTVAGKQMLLDCGLIQGGKADELRNHEPFSFDPLAISAVV
CCEEEEECCCCHHCCCCEEEEEECCCHHHHHCCCCCCCCCHHCCCCCCCCCCHHHHHHHH
LSHAHIDHSGRLPLLVKAGYTGPIFTHKATAELCAIMLKDAAMLQVRDTERTNKKRAKHE
HHHHCCCCCCCCCEEEECCCCCCCEECHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHC
LDPLEPLFTVEDAEQAITQFVSLEYGQVTRVIPHVDICLSDAGHILGSALVELWLGEGKA
CCCCCCEEEHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
QKKLVFSGDLGRAGMPILRNPTLVDTADLVLMESTYGNRFHRSWTDTLAELKAIFAKAVT
CCEEEEECCCCCCCCCCCCCCCEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
ESHGNILLPAFSVGRAQELLYLFHLYAKEWDLSRWKVCLDSPMAIEATRVYVNNYPLMDD
CCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEEEEEEECCCCCCH
DFKRFTRQHPGQHPLLSNVEFIQTTEESIALNDVHKGLIIIAGSGMCNGGRIRSHLEHNL
HHHHHHHHCCCCCCCCCCCHHEEECCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCC
WRPECDVIICGYQALGTPGRALVDGVEELTIHGNSIKVAAKLHTVGGLSAHADQAELLRW
CCCCCCEEEECCHHCCCCCHHHHCCCHHEEEECCEEEEEEEEEECCCCCCCCCHHHHHHH
YRHFESQPPLVLVHGEPEAQQGLVAVMNQDSKTKPKALAIATRGDMLDLNALPKLVWVTN
HHHHCCCCCEEEEECCCCHHCCEEEEECCCCCCCCCEEEEEECCCEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA