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The map label for this gene is emrK [H]

Identifier: 117918976

GI number: 117918976

Start: 612889

End: 613944

Strand: Direct

Name: emrK [H]

Synonym: Shewana3_0522

Alternate gene names: 117918976

Gene position: 612889-613944 (Clockwise)

Preceding gene: 117918973

Following gene: 117918977

Centisome position: 12.33

GC content: 53.03

Gene sequence:

>1056_bases
ATGTCCAAAAGTAAACTCATCATCGCCGTTCCACTATTGCTCGCCGCCGTTGCGGGTGGCGGTTATTACTGGTGGACGCA
AGTACGTTTTATCGAAACCACTGACAACGCCTATGTCGAGGCCGATATCTCCCATGTGAGCGTGAAAGTCCCAGGTTATG
TGGTGTTATCCGATGTGACCGATAACCAACATGTGCGCAAGGGCGAGTTATTAGCGCAACTTGAAGATAATCAGTTTAGC
GCTAAAGTCAGCCAAGCCGAGGCGTTACTCGCCAGTGCTAAGGCCGATATGCAAACCTTAGCCGCTAAGGTGGAATTGCA
GCACGCGTTGATCAGCCAAGCGAGTGCGGGCGTGGTGGCGGCGCAGGCCGACAAACTGCGTGCCGAGCAACAGTTAAGCC
GAGCTAAAAAGTTAAAAGTCAGCAACTACAGCTCACAGGACGATGTCGACCAATTACAAGCAGGTTTTGATTCCGCTGCC
GCTGGGCTAGATGAAGCCAAGGCACTGTTAGTGGCTAAAGAGCGTGAGCTCGCTGTATTTAATGCCCAGCTGAATCAGGC
TGGTTCTGTGGTTGAACAGTCGAATGCGGCATTGGAGCTGGCTAAAATTCAGCTTAATGATACCCGCGTGACCGCGCCTT
TCTCTGGGGTGATTGGTAAACGCGGCGCTATGGTGGGGCAGTATGTACAGCCCGGCCAGGCACTCTACAGTTTGGTTCCG
GATGGGGCTGTGTGGATCACGGCGAACTTTAAAGAAACCCAAATCCAACATATGCAACCTGGACAGTCGGTGCAGGTCAG
TCTCGATGCGTTTCCCGACAAAACCTTTACAGGTGTTATCGATAGTCTGTCGCCGGCGTCCGGAGCCAAATTTAGTCTGC
TGCCCGCCGAAAATGCCACGGGTAACTTCACTAAAATCGTGCAACGTATCCCTGTGCGGATCCGTTTAGATCTCTCAGCA
GAAGAGGCGCGTGTCGTCCCCGGTTTAAGTGCTGTGGTCAAGGTCGATACTGCGTCGCATCCGACGACAGCCATCGCTGC
TAACGTCGGTCGCTAA

Upstream 100 bases:

>100_bases
CATGATTGTTACACCTGTGAAACAGTGGGTTGATTTTTAGATATCTAATAAACGTGATGAGACAGTAGTACACTAGCACT
CACTAATCAAGGAGTCATTC

Downstream 100 bases:

>100_bases
GTAGGTCGTTAACATGAGCACAATTGCTGCGGCACCTGAGGCTATAGTCGCGGGGGCTATACCGAGCGAATATGAGCGCG
GTAGTCGCCGTTCGTGGATT

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSKSKLIIAVPLLLAAVAGGGYYWWTQVRFIETTDNAYVEADISHVSVKVPGYVVLSDVTDNQHVRKGELLAQLEDNQFS
AKVSQAEALLASAKADMQTLAAKVELQHALISQASAGVVAAQADKLRAEQQLSRAKKLKVSNYSSQDDVDQLQAGFDSAA
AGLDEAKALLVAKERELAVFNAQLNQAGSVVEQSNAALELAKIQLNDTRVTAPFSGVIGKRGAMVGQYVQPGQALYSLVP
DGAVWITANFKETQIQHMQPGQSVQVSLDAFPDKTFTGVIDSLSPASGAKFSLLPAENATGNFTKIVQRIPVRIRLDLSA
EEARVVPGLSAVVKVDTASHPTTAIAANVGR

Sequences:

>Translated_351_residues
MSKSKLIIAVPLLLAAVAGGGYYWWTQVRFIETTDNAYVEADISHVSVKVPGYVVLSDVTDNQHVRKGELLAQLEDNQFS
AKVSQAEALLASAKADMQTLAAKVELQHALISQASAGVVAAQADKLRAEQQLSRAKKLKVSNYSSQDDVDQLQAGFDSAA
AGLDEAKALLVAKERELAVFNAQLNQAGSVVEQSNAALELAKIQLNDTRVTAPFSGVIGKRGAMVGQYVQPGQALYSLVP
DGAVWITANFKETQIQHMQPGQSVQVSLDAFPDKTFTGVIDSLSPASGAKFSLLPAENATGNFTKIVQRIPVRIRLDLSA
EEARVVPGLSAVVKVDTASHPTTAIAANVGR
>Mature_350_residues
SKSKLIIAVPLLLAAVAGGGYYWWTQVRFIETTDNAYVEADISHVSVKVPGYVVLSDVTDNQHVRKGELLAQLEDNQFSA
KVSQAEALLASAKADMQTLAAKVELQHALISQASAGVVAAQADKLRAEQQLSRAKKLKVSNYSSQDDVDQLQAGFDSAAA
GLDEAKALLVAKERELAVFNAQLNQAGSVVEQSNAALELAKIQLNDTRVTAPFSGVIGKRGAMVGQYVQPGQALYSLVPD
GAVWITANFKETQIQHMQPGQSVQVSLDAFPDKTFTGVIDSLSPASGAKFSLLPAENATGNFTKIVQRIPVRIRLDLSAE
EARVVPGLSAVVKVDTASHPTTAIAANVGR

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=330, Percent_Identity=31.8181818181818, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1789041, Length=333, Percent_Identity=31.5315315315315, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1790519, Length=292, Percent_Identity=29.4520547945205, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87081951, Length=339, Percent_Identity=23.3038348082596, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790024, Length=240, Percent_Identity=26.25, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790012, Length=247, Percent_Identity=27.1255060728745, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787013, Length=299, Percent_Identity=26.7558528428094, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 37306; Mature: 37174

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSKLIIAVPLLLAAVAGGGYYWWTQVRFIETTDNAYVEADISHVSVKVPGYVVLSDVT
CCCCCEEEEHHHHHHHHCCCCEEEEEEEEEEEECCCEEEEEECEEEEEECCCEEEEEECC
DNQHVRKGELLAQLEDNQFSAKVSQAEALLASAKADMQTLAAKVELQHALISQASAGVVA
CCCCCCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
AQADKLRAEQQLSRAKKLKVSNYSSQDDVDQLQAGFDSAAAGLDEAKALLVAKERELAVF
EHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHCCCCHHHCCHHHHHEEEEECCCCEEEE
NAQLNQAGSVVEQSNAALELAKIQLNDTRVTAPFSGVIGKRGAMVGQYVQPGQALYSLVP
ECHHHHCCCHHHCCCCEEEEEEEEECCCEEECCHHHHHCCCCCHHCCCCCCCHHHHHHCC
DGAVWITANFKETQIQHMQPGQSVQVSLDAFPDKTFTGVIDSLSPASGAKFSLLPAENAT
CCEEEEEECCCHHHHHHCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCEEEEEECCCCC
GNFTKIVQRIPVRIRLDLSAEEARVVPGLSAVVKVDTASHPTTAIAANVGR
CHHHHHHHHCCEEEEEECCCCCCEECCCCEEEEEEECCCCCCEEEEECCCC
>Mature Secondary Structure 
SKSKLIIAVPLLLAAVAGGGYYWWTQVRFIETTDNAYVEADISHVSVKVPGYVVLSDVT
CCCCEEEEHHHHHHHHCCCCEEEEEEEEEEEECCCEEEEEECEEEEEECCCEEEEEECC
DNQHVRKGELLAQLEDNQFSAKVSQAEALLASAKADMQTLAAKVELQHALISQASAGVVA
CCCCCCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
AQADKLRAEQQLSRAKKLKVSNYSSQDDVDQLQAGFDSAAAGLDEAKALLVAKERELAVF
EHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHCCCCHHHCCHHHHHEEEEECCCCEEEE
NAQLNQAGSVVEQSNAALELAKIQLNDTRVTAPFSGVIGKRGAMVGQYVQPGQALYSLVP
ECHHHHCCCHHHCCCCEEEEEEEEECCCEEECCHHHHHCCCCCHHCCCCCCCHHHHHHCC
DGAVWITANFKETQIQHMQPGQSVQVSLDAFPDKTFTGVIDSLSPASGAKFSLLPAENAT
CCEEEEEECCCHHHHHHCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCEEEEEECCCCC
GNFTKIVQRIPVRIRLDLSAEEARVVPGLSAVVKVDTASHPTTAIAANVGR
CHHHHHHHHCCEEEEEECCCCCCEECCCCEEEEEEECCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]