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The map label for this gene is ubiA [H]

Identifier: 117918925

GI number: 117918925

Start: 547026

End: 547886

Strand: Direct

Name: ubiA [H]

Synonym: Shewana3_0470

Alternate gene names: 117918925

Gene position: 547026-547886 (Clockwise)

Preceding gene: 117918924

Following gene: 117918929

Centisome position: 11.0

GC content: 49.71

Gene sequence:

>861_bases
ATGAATCTAAAGCAGAAGTGGGACGTGTATTCCCGCCTGACTCGACTCGACCGTCCTATCGGCACTTTGTTATTGCTCTG
GCCCTGTTTAATGGCGCTGGTATTAGCAGCGGGGGGAATGCCCGATATTAAAGTGTTGATTATCTTTATTATCGGTGTGG
TGATCATGCGTGCCTGTGGCTGCATTATTAACGACTATGCCGACCGCGACCTCGACTCCCACGTTGAACGCACTAAATCC
CGTCCCCTCGCCAGCGGTGAAATCAGCACCAAAGAAGCGCTATTGCTGTTTGTGATCTTAGGGTTGGCCGCGTTTGGTTT
AGTCTTACTGCTCAATGGTTTAGTGGTTAAGCTCTCTGTTGTCGGCATTATCCTCACCATTATCTACCCCTTTACAAAGC
GGGTAACGAACATGCCGCAGATGTTTTTAGGCGTGGTGTGGAGCTGGTCGATTCCCATGGCCTATGCGGCGCAAACCGGT
GAAGTGCCCATCGAAGCCTGGTGGTTATTTGCCGCCAATTGGTTCTGGACTGTGGCTTACGACACCATGTACGCCATGGT
CGATAGGGATGATGATTTAAAGGTCGGTATCAAATCGACCGCCATTCTTTTTGGCAAGTACGACCGCCAAATCATTGGAT
TATTCCAACTTGCTGCGCTGCTGTGTTTTATCGCCGCGGGTTGGAGCGCCGACCGTGGCCTGCTCTATGGTCTAGGACTG
CTTACCTTTGTTGGTTTTAGCACTTACCAACAGATGTTAATTTTTGGCCGCGAAAGAGCTCCTTGCTTTAAAGCCTTCCT
CAACAATAACTGGGCGGGATTAGCACTGTTTGTTGGTTTAGGCGCCGATTACCTGTTTTAA

Upstream 100 bases:

>100_bases
ACAGCTTCAGCCTGCGCAAATTCGCTTAAAAGGGGGCTAGGGTATATGATGCTTACCCTAGCAACCGAGATAAAAAATTA
GGTTTGGGAGTAGCTAGTTA

Downstream 100 bases:

>100_bases
GTTTCCCTCTCCGTTTGTATGAGTGCTATCAGGCGTGTCGCCTGATAGCCGCTCAAAACTCATAAAAAACCTGCTCAACA
TTCAACTCATTGACTCGATG

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MNLKQKWDVYSRLTRLDRPIGTLLLLWPCLMALVLAAGGMPDIKVLIIFIIGVVIMRACGCIINDYADRDLDSHVERTKS
RPLASGEISTKEALLLFVILGLAAFGLVLLLNGLVVKLSVVGIILTIIYPFTKRVTNMPQMFLGVVWSWSIPMAYAAQTG
EVPIEAWWLFAANWFWTVAYDTMYAMVDRDDDLKVGIKSTAILFGKYDRQIIGLFQLAALLCFIAAGWSADRGLLYGLGL
LTFVGFSTYQQMLIFGRERAPCFKAFLNNNWAGLALFVGLGADYLF

Sequences:

>Translated_286_residues
MNLKQKWDVYSRLTRLDRPIGTLLLLWPCLMALVLAAGGMPDIKVLIIFIIGVVIMRACGCIINDYADRDLDSHVERTKS
RPLASGEISTKEALLLFVILGLAAFGLVLLLNGLVVKLSVVGIILTIIYPFTKRVTNMPQMFLGVVWSWSIPMAYAAQTG
EVPIEAWWLFAANWFWTVAYDTMYAMVDRDDDLKVGIKSTAILFGKYDRQIIGLFQLAALLCFIAAGWSADRGLLYGLGL
LTFVGFSTYQQMLIFGRERAPCFKAFLNNNWAGLALFVGLGADYLF
>Mature_286_residues
MNLKQKWDVYSRLTRLDRPIGTLLLLWPCLMALVLAAGGMPDIKVLIIFIIGVVIMRACGCIINDYADRDLDSHVERTKS
RPLASGEISTKEALLLFVILGLAAFGLVLLLNGLVVKLSVVGIILTIIYPFTKRVTNMPQMFLGVVWSWSIPMAYAAQTG
EVPIEAWWLFAANWFWTVAYDTMYAMVDRDDDLKVGIKSTAILFGKYDRQIIGLFQLAALLCFIAAGWSADRGLLYGLGL
LTFVGFSTYQQMLIFGRERAPCFKAFLNNNWAGLALFVGLGADYLF

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=277, Percent_Identity=36.101083032491, Blast_Score=156, Evalue=2e-38,
Organism=Escherichia coli, GI1790473, Length=281, Percent_Identity=51.9572953736655, Blast_Score=281, Evalue=5e-77,
Organism=Escherichia coli, GI1786631, Length=162, Percent_Identity=30.8641975308642, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17553718, Length=280, Percent_Identity=35.3571428571429, Blast_Score=170, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI32565247, Length=286, Percent_Identity=34.6153846153846, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17553720, Length=347, Percent_Identity=28.5302593659942, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32565245, Length=137, Percent_Identity=43.0656934306569, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI32565243, Length=136, Percent_Identity=42.6470588235294, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324370, Length=297, Percent_Identity=31.3131313131313, Blast_Score=140, Evalue=3e-34,
Organism=Drosophila melanogaster, GI21355567, Length=277, Percent_Identity=39.7111913357401, Blast_Score=183, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 31899; Mature: 31899

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHCCHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA