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The map label for this gene is moaE [H]

Identifier: 117918734

GI number: 117918734

Start: 311643

End: 312110

Strand: Direct

Name: moaE [H]

Synonym: Shewana3_0277

Alternate gene names: 117918734

Gene position: 311643-312110 (Clockwise)

Preceding gene: 117918733

Following gene: 117918735

Centisome position: 6.27

GC content: 52.35

Gene sequence:

>468_bases
ATGCGTTTACTGCCAAATGTGCGGGTGCAAACCGTCGATTTTAATGTGGCCGATGAATACCACCAATTAGCCCAAGACAA
TAGCGATGGCGCCGTTGTCACCTTTGTGGGCAAGGTGCGCGACTTTAACGACGGCTCAGTGGTGACCGACCTGACCTTAG
AACACTATCCCTGTATGACTGAGCGTGTGCTCGAGCAAATTGTGGCCGAAGCGCGTGAGCGTTGGCCGCTCAATAAAGTT
ACGGTTATCCACCGCGTCGGTACTATGGCGCTGGGTGAGCAAATTGTGTTTATTGGTGTCACCAGTGCCCATCGCAAGGC
GGCGTTTGCGGCCTGCGAATTCTTAATCGACTTTTTGAAAACCAAAGCCCCTTTCTGGAAATTAGAAGCCGGGGATAAGG
GCAAGAATTGGGTCGAAGCCAAGGACGCCGATGAGCAAGCGGCGCAACTGTGGCAACACAAAGACTAA

Upstream 100 bases:

>100_bases
AAATTGCTGGTGGCGGTGAATCAAACCATCAGCCAGTGGGATACCCGTGTGAGCGATGGTGATGAAGTCGCCTTCTTCCC
GCCTGTGACAGGAGGTTGAT

Downstream 100 bases:

>100_bases
CGTAAGACTGAGCTAGCAGTAGGCGAGAGAGGTGAGTTTATGCATGGTGTGACAGGGTTAGGCAAAATCTGGAGTCTAGT
ATTTGCTCTGGCATTGTCGT

Product: molybdopterin synthase subunit MoaE

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MRLLPNVRVQTVDFNVADEYHQLAQDNSDGAVVTFVGKVRDFNDGSVVTDLTLEHYPCMTERVLEQIVAEARERWPLNKV
TVIHRVGTMALGEQIVFIGVTSAHRKAAFAACEFLIDFLKTKAPFWKLEAGDKGKNWVEAKDADEQAAQLWQHKD

Sequences:

>Translated_155_residues
MRLLPNVRVQTVDFNVADEYHQLAQDNSDGAVVTFVGKVRDFNDGSVVTDLTLEHYPCMTERVLEQIVAEARERWPLNKV
TVIHRVGTMALGEQIVFIGVTSAHRKAAFAACEFLIDFLKTKAPFWKLEAGDKGKNWVEAKDADEQAAQLWQHKD
>Mature_155_residues
MRLLPNVRVQTVDFNVADEYHQLAQDNSDGAVVTFVGKVRDFNDGSVVTDLTLEHYPCMTERVLEQIVAEARERWPLNKV
TVIHRVGTMALGEQIVFIGVTSAHRKAAFAACEFLIDFLKTKAPFWKLEAGDKGKNWVEAKDADEQAAQLWQHKD

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=120, Percent_Identity=36.6666666666667, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1787003, Length=138, Percent_Identity=60.1449275362319, Blast_Score=181, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17509279, Length=127, Percent_Identity=37.007874015748, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356259, Length=126, Percent_Identity=37.3015873015873, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17527; Mature: 17527

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLPNVRVQTVDFNVADEYHQLAQDNSDGAVVTFVGKVRDFNDGSVVTDLTLEHYPCMT
CCCCCCCEEEEEECCHHHHHHHHHCCCCCCEEEEEEECCEECCCCCEEEEEECCCCCCHH
ERVLEQIVAEARERWPLNKVTVIHRVGTMALGEQIVFIGVTSAHRKAAFAACEFLIDFLK
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHH
TKAPFWKLEAGDKGKNWVEAKDADEQAAQLWQHKD
CCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MRLLPNVRVQTVDFNVADEYHQLAQDNSDGAVVTFVGKVRDFNDGSVVTDLTLEHYPCMT
CCCCCCCEEEEEECCHHHHHHHHHCCCCCCEEEEEEECCEECCCCCEEEEEECCCCCCHH
ERVLEQIVAEARERWPLNKVTVIHRVGTMALGEQIVFIGVTSAHRKAAFAACEFLIDFLK
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHH
TKAPFWKLEAGDKGKNWVEAKDADEQAAQLWQHKD
CCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]