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The map label for this gene is moaC

Identifier: 117918732

GI number: 117918732

Start: 310891

End: 311370

Strand: Direct

Name: moaC

Synonym: Shewana3_0275

Alternate gene names: 117918732

Gene position: 310891-311370 (Clockwise)

Preceding gene: 117918731

Following gene: 117918733

Centisome position: 6.25

GC content: 53.75

Gene sequence:

>480_bases
ATGAGCAATGTATTTACCCATATTAACGCCGACGGCAATGCCCATATGGTCGATGTGACCGAGAAAGCCGTGACCGAGCG
CGAGGCCCGTGCCGAAGCCTTTATTGAGATGGCGAGCACGACACTCGAGATGATCATGAGCGGCAGCCACCATAAGGGCG
ATGTGTTTGCCACTGCGCGTATCGCGGGGATCCAAGCGGCGAAAAAGACTTCAGATTTAATTCCGTTATGCCATCCGTTA
ATGCTAACCAAGGTCGAAGTCGAGCTCGAGGCTCAGCCTGAACATAATCGCGTGCGCATCACTAGCCTGTGTAAATTGTC
CGGCAAAACCGGTGTCGAAATGGAGGCGCTCACGGCGGCCTCTGTCGCGGCGTTGACGATTTACGACATGTGTAAAGCCG
TGCAGAAAGACATGGTGATTTCACAGGTGCGCCTGCTCGAAAAACGCGGCGGCAAGTCGGGGCACTTTAAAGCTGAATAA

Upstream 100 bases:

>100_bases
TTTAGTCTGCTTATCGCGTTATCTTTCATTAAGTTAGATTTCGCGATGGCGCTTAACTTCCCTATGCTTGAATTTGGCAT
CAGTTTAAAGGATCGCTTCA

Downstream 100 bases:

>100_bases
CGTAAAGCGAGATAAGAATATGATTAACGTGTTGTTTTTTGCCCAAGTTCGTGAGCTTTTAGGAACTGCCCAACTGAGTG
TTGAAGCGAGCGAGCAGACA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSNVFTHINADGNAHMVDVTEKAVTEREARAEAFIEMASTTLEMIMSGSHHKGDVFATARIAGIQAAKKTSDLIPLCHPL
MLTKVEVELEAQPEHNRVRITSLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKAE

Sequences:

>Translated_159_residues
MSNVFTHINADGNAHMVDVTEKAVTEREARAEAFIEMASTTLEMIMSGSHHKGDVFATARIAGIQAAKKTSDLIPLCHPL
MLTKVEVELEAQPEHNRVRITSLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKAE
>Mature_158_residues
SNVFTHINADGNAHMVDVTEKAVTEREARAEAFIEMASTTLEMIMSGSHHKGDVFATARIAGIQAAKKTSDLIPLCHPLM
LTKVEVELEAQPEHNRVRITSLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKAE

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=155, Percent_Identity=80, Blast_Score=255, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI32566331, Length=155, Percent_Identity=40, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28574490, Length=155, Percent_Identity=49.0322580645161, Blast_Score=146, Evalue=7e-36,
Organism=Drosophila melanogaster, GI28574492, Length=144, Percent_Identity=50, Blast_Score=136, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_SHEON (Q8E942)

Other databases:

- EMBL:   AE014299
- RefSeq:   NP_719972.1
- ProteinModelPortal:   Q8E942
- SMR:   Q8E942
- GeneID:   1172048
- GenomeReviews:   AE014299_GR
- KEGG:   son:SO_4451
- TIGR:   SO_4451
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   PRK09364
- BioCyc:   SONE211586:SO_4451-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17294; Mature: 17163

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVFTHINADGNAHMVDVTEKAVTEREARAEAFIEMASTTLEMIMSGSHHKGDVFATAR
CCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHH
IAGIQAAKKTSDLIPLCHPLMLTKVEVELEAQPEHNRVRITSLCKLSGKTGVEMEALTAA
HHHHHHHHHCCCCCHHHHHHHHEEEEEEEECCCCCCEEEEEHEEEECCCCCCCHHHHHHH
SVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SNVFTHINADGNAHMVDVTEKAVTEREARAEAFIEMASTTLEMIMSGSHHKGDVFATAR
CCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHH
IAGIQAAKKTSDLIPLCHPLMLTKVEVELEAQPEHNRVRITSLCKLSGKTGVEMEALTAA
HHHHHHHHHCCCCCHHHHHHHHEEEEEEEECCCCCCEEEEEHEEEECCCCCCCHHHHHHH
SVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813