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The map label for this gene is moaA [H]

Identifier: 117918731

GI number: 117918731

Start: 309765

End: 310778

Strand: Direct

Name: moaA [H]

Synonym: Shewana3_0274

Alternate gene names: 117918731

Gene position: 309765-310778 (Clockwise)

Preceding gene: 117918728

Following gene: 117918732

Centisome position: 6.23

GC content: 49.9

Gene sequence:

>1014_bases
ATGCACTCGCCTCCCACACTTGGAAAGGTGATCATGTCTCAATTGCAAGACAATTTTGGTCGTAAATTTCATTACTTACG
AATGTCAGTCACTGACGTTTGTAACTTCAAATGCAGTTATTGCCTCCCCGATGGTTATCATCCGAATGGCAAACAACAGT
TTTTATCTCTCAGTGAGATAGAAAACCTTGTGTCCGCATTTAGCCAGGTTGGCACTCAAAAAATCCGTATCACTGGCGGC
GAACCCACGCTGCGCAAAGATTTTACCGATATCATTCGAGTGGTCGCCGACAATCCTCGTATTCATACCGTAGCAACTAC
CACTAATGGGTATAGGCTCGAGAAGCATGCCCAAGAGTGGTTCGACGCGGGGCTACGCCGTATCAATGTGTCGGTAGACA
GCTTAGATCCTAAGATGTTTTACCAGATCACCGGCGAGAATAAGTTCGACGAGGTGATGCGTGGTATCGATGCCGCCTTA
TCTGCGGGGTTTGAGCGCGTGAAGGTCAATGCGGTATTGCTCAAGGGTATGAACGATAAAGATTTACCGCGCTTTTTGAA
TTGGATTAAGCACACGCCCATCGATCTGCGTTTTATCGAGCTGATGGAAACAGGCCTTGGCCGCGAGTATTTCCAAGCTC
ACCATTTGGCGGGGGCCGATATTAAAGCGCAGCTGCAAGCTGAGGGTTGGCAATTAGATACGCCCCGTGCCGACGATGGC
CCAGCGCAAAACTTCAGCCACAGTGACTTTAAGGGCCGTATCGGCTTGATCATGCCCTACGCCACTAACTTCTGCGCGAG
CTGTAATCGCTTGCGGGTCTCGGCCAAGGGTAAGTTGCACTTATGCCTCTTTACCGAGTCTGGCATTGATTTGCGTGATC
TACTGCAACACCCGAGTCAGCAAGCGGAATTAATCGAGCGGTTACACGGTCAACTGGCGCAGAAGAAGGAAACCCATTAT
CTGCATCAGGGCATTACCGGTGTGACGCAACATCTGGCCTCGATTGGCGGTTAA

Upstream 100 bases:

>100_bases
GGCTTATAATCACGAATGACGGTTCTCCGAGCTTGCCTACCTAAGTCGACAGATATGGGGGTGTAGCCGTGGTAATAAGG
CCACTGGGGTGAGTAAAGAA

Downstream 100 bases:

>100_bases
TCTAACTTAGGTTTTAGTCTGCTTATCGCGTTATCTTTCATTAAGTTAGATTTCGCGATGGCGCTTAACTTCCCTATGCT
TGAATTTGGCATCAGTTTAA

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MHSPPTLGKVIMSQLQDNFGRKFHYLRMSVTDVCNFKCSYCLPDGYHPNGKQQFLSLSEIENLVSAFSQVGTQKIRITGG
EPTLRKDFTDIIRVVADNPRIHTVATTTNGYRLEKHAQEWFDAGLRRINVSVDSLDPKMFYQITGENKFDEVMRGIDAAL
SAGFERVKVNAVLLKGMNDKDLPRFLNWIKHTPIDLRFIELMETGLGREYFQAHHLAGADIKAQLQAEGWQLDTPRADDG
PAQNFSHSDFKGRIGLIMPYATNFCASCNRLRVSAKGKLHLCLFTESGIDLRDLLQHPSQQAELIERLHGQLAQKKETHY
LHQGITGVTQHLASIGG

Sequences:

>Translated_337_residues
MHSPPTLGKVIMSQLQDNFGRKFHYLRMSVTDVCNFKCSYCLPDGYHPNGKQQFLSLSEIENLVSAFSQVGTQKIRITGG
EPTLRKDFTDIIRVVADNPRIHTVATTTNGYRLEKHAQEWFDAGLRRINVSVDSLDPKMFYQITGENKFDEVMRGIDAAL
SAGFERVKVNAVLLKGMNDKDLPRFLNWIKHTPIDLRFIELMETGLGREYFQAHHLAGADIKAQLQAEGWQLDTPRADDG
PAQNFSHSDFKGRIGLIMPYATNFCASCNRLRVSAKGKLHLCLFTESGIDLRDLLQHPSQQAELIERLHGQLAQKKETHY
LHQGITGVTQHLASIGG
>Mature_337_residues
MHSPPTLGKVIMSQLQDNFGRKFHYLRMSVTDVCNFKCSYCLPDGYHPNGKQQFLSLSEIENLVSAFSQVGTQKIRITGG
EPTLRKDFTDIIRVVADNPRIHTVATTTNGYRLEKHAQEWFDAGLRRINVSVDSLDPKMFYQITGENKFDEVMRGIDAAL
SAGFERVKVNAVLLKGMNDKDLPRFLNWIKHTPIDLRFIELMETGLGREYFQAHHLAGADIKAQLQAEGWQLDTPRADDG
PAQNFSHSDFKGRIGLIMPYATNFCASCNRLRVSAKGKLHLCLFTESGIDLRDLLQHPSQQAELIERLHGQLAQKKETHY
LHQGITGVTQHLASIGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=307, Percent_Identity=35.1791530944625, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI22027536, Length=307, Percent_Identity=35.1791530944625, Blast_Score=199, Evalue=3e-51,
Organism=Escherichia coli, GI1786999, Length=329, Percent_Identity=57.7507598784195, Blast_Score=409, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI32566331, Length=307, Percent_Identity=36.8078175895765, Blast_Score=199, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI32566329, Length=307, Percent_Identity=36.8078175895765, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17561210, Length=307, Percent_Identity=36.4820846905537, Blast_Score=196, Evalue=1e-50,
Organism=Drosophila melanogaster, GI28574488, Length=322, Percent_Identity=34.1614906832298, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI28574490, Length=312, Percent_Identity=34.2948717948718, Blast_Score=191, Evalue=8e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 37977; Mature: 37977

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSPPTLGKVIMSQLQDNFGRKFHYLRMSVTDVCNFKCSYCLPDGYHPNGKQQFLSLSEI
CCCCCHHHHHHHHHHHHHHCCEEEEEEEEHHHHHCCCEEEECCCCCCCCHHHHHHHHHHH
ENLVSAFSQVGTQKIRITGGEPTLRKDFTDIIRVVADNPRIHTVATTTNGYRLEKHAQEW
HHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEHHHHHHHH
FDAGLRRINVSVDSLDPKMFYQITGENKFDEVMRGIDAALSAGFERVKVNAVLLKGMNDK
HHHHHHEEEEEHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCHHHEEEEEEEEECCCCC
DLPRFLNWIKHTPIDLRFIELMETGLGREYFQAHHLAGADIKAQLQAEGWQLDTPRADDG
CHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEECCEECCCCCCCCC
PAQNFSHSDFKGRIGLIMPYATNFCASCNRLRVSAKGKLHLCLFTESGIDLRDLLQHPSQ
CCCCCCCCCCCCCEEEEECHHHHHHHCCCCEEEECCCCEEEEEEECCCCCHHHHHHCCCH
QAELIERLHGQLAQKKETHYLHQGITGVTQHLASIGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHSPPTLGKVIMSQLQDNFGRKFHYLRMSVTDVCNFKCSYCLPDGYHPNGKQQFLSLSEI
CCCCCHHHHHHHHHHHHHHCCEEEEEEEEHHHHHCCCEEEECCCCCCCCHHHHHHHHHHH
ENLVSAFSQVGTQKIRITGGEPTLRKDFTDIIRVVADNPRIHTVATTTNGYRLEKHAQEW
HHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEHHHHHHHH
FDAGLRRINVSVDSLDPKMFYQITGENKFDEVMRGIDAALSAGFERVKVNAVLLKGMNDK
HHHHHHEEEEEHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCHHHEEEEEEEEECCCCC
DLPRFLNWIKHTPIDLRFIELMETGLGREYFQAHHLAGADIKAQLQAEGWQLDTPRADDG
CHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEECCEECCCCCCCCC
PAQNFSHSDFKGRIGLIMPYATNFCASCNRLRVSAKGKLHLCLFTESGIDLRDLLQHPSQ
CCCCCCCCCCCCCEEEEECHHHHHHHCCCCEEEECCCCEEEEEEECCCCCHHHHHHCCCH
QAELIERLHGQLAQKKETHYLHQGITGVTQHLASIGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA