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The map label for this gene is selA [H]

Identifier: 117918564

GI number: 117918564

Start: 121113

End: 122543

Strand: Direct

Name: selA [H]

Synonym: Shewana3_0106

Alternate gene names: 117918564

Gene position: 121113-122543 (Clockwise)

Preceding gene: 117918563

Following gene: 117918565

Centisome position: 2.44

GC content: 55.9

Gene sequence:

>1431_bases
ATGATACAAATGATGACCCAAGTACCCGATACACCCCAAGCCCTGTACCGCGCGCTGCCGTCGATGGACAGTCTGCTCGC
CGATGCAATATTGGCGCCCCTGCTGCAAAGCTATGGTAAAGCGGCGGTAAAGGCGGCGCTGGATAGCCAGTTACGCACGG
CGCGTGAGCTGATAGCTCAGGAGCGACGTTTACCCGCTTGGTGTGCTAACCCGTCATTATTGAACGGATATTTGGTTGAT
CAATTGTCTAAGGACTATAGCCATAGTCTTAAGCCCGTGTGGAACCTCACGGGAACTATCCTGCATACCAATCTTGGTCG
CGCCCAGCAGTCTGAGGCGGCCATTCGGGCGGTGACCTCTGTGATGCGTTATCCCACGCCGCTGGAATTTGAGTTGGCAG
CGGGTGAACGCGGCCATCGGGATAATGCCATTAGTGGGTTAATCCAGCGCTTAACAGGAGCTGAGGCCTGCTGCGTGGTG
AATAACAACGCCGCTGCTGTGTTGCTGATGTTGTCGGCGGTGGCGGCGGGTAAAGAAGTGATTGTCTCCCGCGGCGAGCT
GGTGGAAATCGGCGGCGCCTTTCGTATTCCTGACATTATGCGCCAAGCGGGCTGTATCTTAGTGGAAGTTGGCAGCACTA
ATCGTACTCACCTTAAGGACTATGAGCAGGCGATCACCGAAAATACCGCCGCCATCATGAAGGTGCACACCAGCAACTAC
CATATCAGTGGCTTTACCGCTTCGGTGGATGAGGCCAGATTAGGCCAACTCTGCCGCGAGCGTGGGGTCGCGCTGATTTC
GGATCTTGGCAGTGGTTCACTCACCGACTTACGCCGTTTTGGCCTGAAACAAGAGCCGACTCCCCAAGCCATGCTGGCGG
ATGGGGTCGATCTGGTTAGCTTCTCCGGCGATAAACTCCTTGGCGGCCCGCAATCGGGTTTGATTGTCGGCAAACAGGCG
CTGATCAACAAACTTCAAAGTCATCCGCTCAAGCGTGCATTGCGCTGCGACAAGCTGATTCTCGCGGCGCTCGAGGCGAC
GCTGATCCACTATTTGAACCCCGAAACCTTGGATCGGGAACTGCCGATTATGGCTAAATTTGCCCGCAGCCAAGCTGAGT
TACGTCAAATCGGTGAGCGTCTGCAGCGCGCCTTAGAGCCGCTGTTTGCACCGAGTTATGGCATCGAGCTAGTGGAGTGC
CAAACCCAAGTCGGTAGCGGCTCGCAGCCCGATACCTTTTTGCCCTCAATCGCCCTGTGCTTTAACGCGCAAGAGGGCGG
CAGTTTAACGTTGCTCGAGCAGCATTTTAAGCAGGCGCAGCGCCCTGTGATTGGCCGTATGACCCAAGATCAACTTCGCC
TCGATCTGCGCGGTATCGATGATGAGGCCGAGTTGTTAGCCGAACTCAGCACCTTAGGTGTGCAGCTATGA

Upstream 100 bases:

>100_bases
TGGGGCGACCACTGTCAATCCATTGCTACTGGCCCACGAAACTGAGCAATAACCAAAGTCGGGAAGGGCTCACCGAGTCC
TTCCCCTTATATTTATCAAG

Downstream 100 bases:

>100_bases
TTATGGTCACCGCGGGCCATGTCGACCACGGCAAGAGCACGTTGATCCGTGCCTTAACGGGGATGAACACCGACAGGCTC
CCCGAAGAAAAACGCCGTGG

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MIQMMTQVPDTPQALYRALPSMDSLLADAILAPLLQSYGKAAVKAALDSQLRTARELIAQERRLPAWCANPSLLNGYLVD
QLSKDYSHSLKPVWNLTGTILHTNLGRAQQSEAAIRAVTSVMRYPTPLEFELAAGERGHRDNAISGLIQRLTGAEACCVV
NNNAAAVLLMLSAVAAGKEVIVSRGELVEIGGAFRIPDIMRQAGCILVEVGSTNRTHLKDYEQAITENTAAIMKVHTSNY
HISGFTASVDEARLGQLCRERGVALISDLGSGSLTDLRRFGLKQEPTPQAMLADGVDLVSFSGDKLLGGPQSGLIVGKQA
LINKLQSHPLKRALRCDKLILAALEATLIHYLNPETLDRELPIMAKFARSQAELRQIGERLQRALEPLFAPSYGIELVEC
QTQVGSGSQPDTFLPSIALCFNAQEGGSLTLLEQHFKQAQRPVIGRMTQDQLRLDLRGIDDEAELLAELSTLGVQL

Sequences:

>Translated_476_residues
MIQMMTQVPDTPQALYRALPSMDSLLADAILAPLLQSYGKAAVKAALDSQLRTARELIAQERRLPAWCANPSLLNGYLVD
QLSKDYSHSLKPVWNLTGTILHTNLGRAQQSEAAIRAVTSVMRYPTPLEFELAAGERGHRDNAISGLIQRLTGAEACCVV
NNNAAAVLLMLSAVAAGKEVIVSRGELVEIGGAFRIPDIMRQAGCILVEVGSTNRTHLKDYEQAITENTAAIMKVHTSNY
HISGFTASVDEARLGQLCRERGVALISDLGSGSLTDLRRFGLKQEPTPQAMLADGVDLVSFSGDKLLGGPQSGLIVGKQA
LINKLQSHPLKRALRCDKLILAALEATLIHYLNPETLDRELPIMAKFARSQAELRQIGERLQRALEPLFAPSYGIELVEC
QTQVGSGSQPDTFLPSIALCFNAQEGGSLTLLEQHFKQAQRPVIGRMTQDQLRLDLRGIDDEAELLAELSTLGVQL
>Mature_476_residues
MIQMMTQVPDTPQALYRALPSMDSLLADAILAPLLQSYGKAAVKAALDSQLRTARELIAQERRLPAWCANPSLLNGYLVD
QLSKDYSHSLKPVWNLTGTILHTNLGRAQQSEAAIRAVTSVMRYPTPLEFELAAGERGHRDNAISGLIQRLTGAEACCVV
NNNAAAVLLMLSAVAAGKEVIVSRGELVEIGGAFRIPDIMRQAGCILVEVGSTNRTHLKDYEQAITENTAAIMKVHTSNY
HISGFTASVDEARLGQLCRERGVALISDLGSGSLTDLRRFGLKQEPTPQAMLADGVDLVSFSGDKLLGGPQSGLIVGKQA
LINKLQSHPLKRALRCDKLILAALEATLIHYLNPETLDRELPIMAKFARSQAELRQIGERLQRALEPLFAPSYGIELVEC
QTQVGSGSQPDTFLPSIALCFNAQEGGSLTLLEQHFKQAQRPVIGRMTQDQLRLDLRGIDDEAELLAELSTLGVQL

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=461, Percent_Identity=55.0976138828633, Blast_Score=438, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 51715; Mature: 51715

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQMMTQVPDTPQALYRALPSMDSLLADAILAPLLQSYGKAAVKAALDSQLRTARELIAQ
CCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERRLPAWCANPSLLNGYLVDQLSKDYSHSLKPVWNLTGTILHTNLGRAQQSEAAIRAVTS
HHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCHHEEECCCCCCHHHHHHHHHHHH
VMRYPTPLEFELAAGERGHRDNAISGLIQRLTGAEACCVVNNNAAAVLLMLSAVAAGKEV
HHHCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCHHH
IVSRGELVEIGGAFRIPDIMRQAGCILVEVGSTNRTHLKDYEQAITENTAAIMKVHTSNY
HHCCCCEEEECCCCCCHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCE
HISGFTASVDEARLGQLCRERGVALISDLGSGSLTDLRRFGLKQEPTPQAMLADGVDLVS
EEECEECCHHHHHHHHHHHHCCCEEEHHCCCCCHHHHHHCCCCCCCCCHHHHHCCCCEEE
FSGDKLLGGPQSGLIVGKQALINKLQSHPLKRALRCDKLILAALEATLIHYLNPETLDRE
CCCCCCCCCCCCCCEECHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC
LPIMAKFARSQAELRQIGERLQRALEPLFAPSYGIELVECQTQVGSGSQPDTFLPSIALC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCHHHCHHHHE
FNAQEGGSLTLLEQHFKQAQRPVIGRMTQDQLRLDLRGIDDEAELLAELSTLGVQL
EECCCCCCCHHHHHHHHHHCCCHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIQMMTQVPDTPQALYRALPSMDSLLADAILAPLLQSYGKAAVKAALDSQLRTARELIAQ
CCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERRLPAWCANPSLLNGYLVDQLSKDYSHSLKPVWNLTGTILHTNLGRAQQSEAAIRAVTS
HHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCHHEEECCCCCCHHHHHHHHHHHH
VMRYPTPLEFELAAGERGHRDNAISGLIQRLTGAEACCVVNNNAAAVLLMLSAVAAGKEV
HHHCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCHHH
IVSRGELVEIGGAFRIPDIMRQAGCILVEVGSTNRTHLKDYEQAITENTAAIMKVHTSNY
HHCCCCEEEECCCCCCHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCE
HISGFTASVDEARLGQLCRERGVALISDLGSGSLTDLRRFGLKQEPTPQAMLADGVDLVS
EEECEECCHHHHHHHHHHHHCCCEEEHHCCCCCHHHHHHCCCCCCCCCHHHHHCCCCEEE
FSGDKLLGGPQSGLIVGKQALINKLQSHPLKRALRCDKLILAALEATLIHYLNPETLDRE
CCCCCCCCCCCCCCEECHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCC
LPIMAKFARSQAELRQIGERLQRALEPLFAPSYGIELVECQTQVGSGSQPDTFLPSIALC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCHHHCHHHHE
FNAQEGGSLTLLEQHFKQAQRPVIGRMTQDQLRLDLRGIDDEAELLAELSTLGVQL
EECCCCCCCHHHHHHHHHHCCCHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]