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The map label for this gene is nagA [H]

Identifier: 116872356

GI number: 116872356

Start: 964176

End: 965309

Strand: Direct

Name: nagA [H]

Synonym: lwe0938

Alternate gene names: 116872356

Gene position: 964176-965309 (Clockwise)

Preceding gene: 116872355

Following gene: 116872357

Centisome position: 34.26

GC content: 36.33

Gene sequence:

>1134_bases
ATGGCTAATAAAGTAATTACTAACGCTACAATTTATACTGGTAAAGGTGTTCTAGAAAACGCTTTTGTGCGTTTTGATGC
ACAAATTTTAGAAGTGGGTTCAATGACTTATTTTCAAGCGAATAAAGCAGAAGCAGTAATCGATGCAAAAGGACAAAAAC
TTGTTCCTGGTTTCATTGATGTTCATTCACATGGTGGATATAGTTTTGATGCAATGGATGCAGATCCAGAAGCACTTAGA
AAACAAGTGAAAGGTATGTTGAATGAAGGGATTACTACTTATTTTCCAACAACAATGACTCAATCACATGAAAATATTGA
AAAAGCTTTAAAAGTTATTAATGAAGTTGCTCAAACAGAACCTATTATTGGCGGGATTCATCTGGAAGGTCCATTTGTTT
CTAAAGTATTTAAAGGAGCTCAGCCAGAAGAATATATTCAAGCGCCTGACTTGGAGCTTTTCAAAAAATGGTTTGATATT
TCTGGTGGTTTGATTAAATTAGTAACCTATGCACCAGAACATGATACTTCTGCTGATTTTGAAAATTTATGTTTTGAATT
AGGAGTTGTTCCAAGTATTGGTCACTCTAATGATGTGCGCGAACACTTGAAAACAAGTAAAGCGACACACGCAACACATT
TATATAATGCTTGTCACCGTATGACACACCGCGAACCTGGTGTTCCTGGGCATGTTTTATTAGAAAAAGGGATTAACGCA
GAATTAATTGTTGATGGTATCCACGTTCATCCAGATATGGTGAAATTAGCCTATCAAATGAAAGGACCTGAACATGTATG
TATTATTACTGATTCGATGCGAGCAAAAGGTATGCCAGAAGGGAAATCGGAACTTGGTGGCCAAACAGTTATCGTGAAAG
ATAAACAAGCTCGCTTAGAAGATGGAACACTTGCTGGAAGTGTATTAACTTATGATGACGGCTTCCGTAATATGATTAAA
TTTACTGGTTGCTCGGTAGAAGAAGCAGTGCTTATGTCTTCTGGAAACCAAGCACGCGAATTTAATTTAACACAAAAAGG
TGCCATTGAGGCAGGTAAAGACGCAGATTTCAACTTATTAGATGAAGATTTACACATTACAGCAACCTATTCATTTGGAA
AAAAACATTCTTGA

Upstream 100 bases:

>100_bases
TTTACTTTTTTTCGGGTAAATAGGAAAAGATAAGTTGCATTTTAATGGATTCATGCTATACTAATTGGTATAGACCGATT
TAACAAGGAGGCAATATGTA

Downstream 100 bases:

>100_bases
GAGGAAGATATTAATATGCAACTTATCACAACAGAAAATAAATTAGCAGGCTCCAAAAAAGCATTAGAAATTATTGAAAA
AGGTATTACGACTGGTGAAG

Product: N-acetylglucosamine-6P-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MANKVITNATIYTGKGVLENAFVRFDAQILEVGSMTYFQANKAEAVIDAKGQKLVPGFIDVHSHGGYSFDAMDADPEALR
KQVKGMLNEGITTYFPTTMTQSHENIEKALKVINEVAQTEPIIGGIHLEGPFVSKVFKGAQPEEYIQAPDLELFKKWFDI
SGGLIKLVTYAPEHDTSADFENLCFELGVVPSIGHSNDVREHLKTSKATHATHLYNACHRMTHREPGVPGHVLLEKGINA
ELIVDGIHVHPDMVKLAYQMKGPEHVCIITDSMRAKGMPEGKSELGGQTVIVKDKQARLEDGTLAGSVLTYDDGFRNMIK
FTGCSVEEAVLMSSGNQAREFNLTQKGAIEAGKDADFNLLDEDLHITATYSFGKKHS

Sequences:

>Translated_377_residues
MANKVITNATIYTGKGVLENAFVRFDAQILEVGSMTYFQANKAEAVIDAKGQKLVPGFIDVHSHGGYSFDAMDADPEALR
KQVKGMLNEGITTYFPTTMTQSHENIEKALKVINEVAQTEPIIGGIHLEGPFVSKVFKGAQPEEYIQAPDLELFKKWFDI
SGGLIKLVTYAPEHDTSADFENLCFELGVVPSIGHSNDVREHLKTSKATHATHLYNACHRMTHREPGVPGHVLLEKGINA
ELIVDGIHVHPDMVKLAYQMKGPEHVCIITDSMRAKGMPEGKSELGGQTVIVKDKQARLEDGTLAGSVLTYDDGFRNMIK
FTGCSVEEAVLMSSGNQAREFNLTQKGAIEAGKDADFNLLDEDLHITATYSFGKKHS
>Mature_376_residues
ANKVITNATIYTGKGVLENAFVRFDAQILEVGSMTYFQANKAEAVIDAKGQKLVPGFIDVHSHGGYSFDAMDADPEALRK
QVKGMLNEGITTYFPTTMTQSHENIEKALKVINEVAQTEPIIGGIHLEGPFVSKVFKGAQPEEYIQAPDLELFKKWFDIS
GGLIKLVTYAPEHDTSADFENLCFELGVVPSIGHSNDVREHLKTSKATHATHLYNACHRMTHREPGVPGHVLLEKGINAE
LIVDGIHVHPDMVKLAYQMKGPEHVCIITDSMRAKGMPEGKSELGGQTVIVKDKQARLEDGTLAGSVLTYDDGFRNMIKF
TGCSVEEAVLMSSGNQAREFNLTQKGAIEAGKDADFNLLDEDLHITATYSFGKKHS

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=418, Percent_Identity=30.1435406698565, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI224922791, Length=417, Percent_Identity=30.2158273381295, Blast_Score=155, Evalue=7e-38,
Organism=Escherichia coli, GI1786892, Length=383, Percent_Identity=32.1148825065274, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17553768, Length=379, Percent_Identity=31.6622691292876, Blast_Score=158, Evalue=5e-39,
Organism=Drosophila melanogaster, GI19920392, Length=386, Percent_Identity=31.0880829015544, Blast_Score=161, Evalue=9e-40,
Organism=Drosophila melanogaster, GI281361140, Length=397, Percent_Identity=29.9748110831234, Blast_Score=157, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41362; Mature: 41231

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKVITNATIYTGKGVLENAFVRFDAQILEVGSMTYFQANKAEAVIDAKGQKLVPGFID
CCCCEEECEEEEECCCHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCCEECCCEEE
VHSHGGYSFDAMDADPEALRKQVKGMLNEGITTYFPTTMTQSHENIEKALKVINEVAQTE
EECCCCEEECCCCCCHHHHHHHHHHHHHCCCEEECCCHHHCCHHHHHHHHHHHHHHHHCC
PIIGGIHLEGPFVSKVFKGAQPEEYIQAPDLELFKKWFDISGGLIKLVTYAPEHDTSADF
CCEEEEEECCHHHHHHHCCCCCHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCH
ENLCFELGVVPSIGHSNDVREHLKTSKATHATHLYNACHRMTHREPGVPGHVLLEKGINA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCE
ELIVDGIHVHPDMVKLAYQMKGPEHVCIITDSMRAKGMPEGKSELGGQTVIVKDKQARLE
EEEEECEECCHHHHHHHHHCCCCCEEEEEECCHHCCCCCCCHHHCCCCEEEEECCHHCCC
DGTLAGSVLTYDDGFRNMIKFTGCSVEEAVLMSSGNQAREFNLTQKGAIEAGKDADFNLL
CCCEECEEEEECCCHHHHHHHCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCEE
DEDLHITATYSFGKKHS
CCCEEEEEEECCCCCCC
>Mature Secondary Structure 
ANKVITNATIYTGKGVLENAFVRFDAQILEVGSMTYFQANKAEAVIDAKGQKLVPGFID
CCCEEECEEEEECCCHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCCEECCCEEE
VHSHGGYSFDAMDADPEALRKQVKGMLNEGITTYFPTTMTQSHENIEKALKVINEVAQTE
EECCCCEEECCCCCCHHHHHHHHHHHHHCCCEEECCCHHHCCHHHHHHHHHHHHHHHHCC
PIIGGIHLEGPFVSKVFKGAQPEEYIQAPDLELFKKWFDISGGLIKLVTYAPEHDTSADF
CCEEEEEECCHHHHHHHCCCCCHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCH
ENLCFELGVVPSIGHSNDVREHLKTSKATHATHLYNACHRMTHREPGVPGHVLLEKGINA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCE
ELIVDGIHVHPDMVKLAYQMKGPEHVCIITDSMRAKGMPEGKSELGGQTVIVKDKQARLE
EEEEECEECCHHHHHHHHHCCCCCEEEEEECCHHCCCCCCCHHHCCCCEEEEECCHHCCC
DGTLAGSVLTYDDGFRNMIKFTGCSVEEAVLMSSGNQAREFNLTQKGAIEAGKDADFNLL
CCCEECEEEEECCCHHHHHHHCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCEE
DEDLHITATYSFGKKHS
CCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA