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The map label for this gene is 116872324

Identifier: 116872324

GI number: 116872324

Start: 937526

End: 938149

Strand: Direct

Name: 116872324

Synonym: lwe0906

Alternate gene names: NA

Gene position: 937526-938149 (Clockwise)

Preceding gene: 116872322

Following gene: 116872325

Centisome position: 33.31

GC content: 35.9

Gene sequence:

>624_bases
ATGAATTCAATTATTAAGGAACATTATTTCGAGCATAAATCCACGATAGAATTAGCGAGAGATATATTAGGTATGCGCTT
AGTCCATCAAACGCAACATGTGAAACTTTCAGGATATATTGTAGAAACAGAAGCTTATCTTGGCGCGACTGATATTGCAG
CTCATAGTTACCGCAATTTAAAAACGAAACGAACAGATATCATGTATCAACCAGCTGGTGCCATCTATATGTATCAAATG
CACCGCCAAGTGTTACTCAATTTTATTACGATGAAAGAGGGAGTTCCAGAGGCTGTTTTAATACGTGCGATTGAACCAGA
TGAAGCTTCGATCCCTTACATGGAAATAAAACGTAATGGAAAAACAGGAAGTGAGCTTACCAATGGACCTGGTAAATTGA
CACAAGCTTTAGGATTAACCATTAAAGATTATGGGAAAACTCTTTTTAATAGTAATATCTGGTTAGAGGAAGCAAAAATC
CCACATATAATAGAAGCAACTAATCGAATTGGTGTACCTAATAAGGGTATTGCAACTCATTATCCTCTAAGGTTCACAGT
AAAAGGAAGTCGTTATATTTCTGGACAACGAAAAGGTCAGATTTTAACAGAAATATGGCAATAA

Upstream 100 bases:

>100_bases
CAAGTATGAATTAACATAATATAGGCTAATATAACTAGCCAAAAAAGAACCATTCAAACGAAAAATCTGCTAGAATAAAA
AGAAAACACTGAGGTATGAA

Downstream 100 bases:

>100_bases
ATTTACATTTTTGTCACAGTTAAAGAAAAATCTTCGCTAGTAGTACTGATATTCTTTGCTTCAGATTAACTGCTACTATA
TAATGAAATAGTTACAAGGA

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MNSIIKEHYFEHKSTIELARDILGMRLVHQTQHVKLSGYIVETEAYLGATDIAAHSYRNLKTKRTDIMYQPAGAIYMYQM
HRQVLLNFITMKEGVPEAVLIRAIEPDEASIPYMEIKRNGKTGSELTNGPGKLTQALGLTIKDYGKTLFNSNIWLEEAKI
PHIIEATNRIGVPNKGIATHYPLRFTVKGSRYISGQRKGQILTEIWQ

Sequences:

>Translated_207_residues
MNSIIKEHYFEHKSTIELARDILGMRLVHQTQHVKLSGYIVETEAYLGATDIAAHSYRNLKTKRTDIMYQPAGAIYMYQM
HRQVLLNFITMKEGVPEAVLIRAIEPDEASIPYMEIKRNGKTGSELTNGPGKLTQALGLTIKDYGKTLFNSNIWLEEAKI
PHIIEATNRIGVPNKGIATHYPLRFTVKGSRYISGQRKGQILTEIWQ
>Mature_207_residues
MNSIIKEHYFEHKSTIELARDILGMRLVHQTQHVKLSGYIVETEAYLGATDIAAHSYRNLKTKRTDIMYQPAGAIYMYQM
HRQVLLNFITMKEGVPEAVLIRAIEPDEASIPYMEIKRNGKTGSELTNGPGKLTQALGLTIKDYGKTLFNSNIWLEEAKI
PHIIEATNRIGVPNKGIATHYPLRFTVKGSRYISGQRKGQILTEIWQ

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632769, Length=200, Percent_Identity=32.5, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI62632771, Length=200, Percent_Identity=32.5, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI62632765, Length=200, Percent_Identity=32.5, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_LISW6 (A0AH42)

Other databases:

- EMBL:   AM263198
- RefSeq:   YP_849105.1
- ProteinModelPortal:   A0AH42
- SMR:   A0AH42
- STRING:   A0AH42
- GeneID:   4463774
- GenomeReviews:   AM263198_GR
- KEGG:   lwe:lwe0906
- NMPDR:   fig|386043.6.peg.879
- eggNOG:   COG2094
- HOGENOM:   HBG664239
- OMA:   AGEEYAN
- ProtClustDB:   PRK00802
- BioCyc:   LWEL386043:LWE0906-MONOMER
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.-

Molecular weight: Translated: 23529; Mature: 23529

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSIIKEHYFEHKSTIELARDILGMRLVHQTQHVKLSGYIVETEAYLGATDIAAHSYRNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEECCCCCHHHHHHHHHHCC
KTKRTDIMYQPAGAIYMYQMHRQVLLNFITMKEGVPEAVLIRAIEPDEASIPYMEIKRNG
CCCCCEEEECCCCEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEECCC
KTGSELTNGPGKLTQALGLTIKDYGKTLFNSNIWLEEAKIPHIIEATNRIGVPNKGIATH
CCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCHHHHHHCCCCCCCCCCCEE
YPLRFTVKGSRYISGQRKGQILTEIWQ
CCEEEEECCCEEECCCCCCCHHHHHCC
>Mature Secondary Structure
MNSIIKEHYFEHKSTIELARDILGMRLVHQTQHVKLSGYIVETEAYLGATDIAAHSYRNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEECCCCCHHHHHHHHHHCC
KTKRTDIMYQPAGAIYMYQMHRQVLLNFITMKEGVPEAVLIRAIEPDEASIPYMEIKRNG
CCCCCEEEECCCCEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEECCC
KTGSELTNGPGKLTQALGLTIKDYGKTLFNSNIWLEEAKIPHIIEATNRIGVPNKGIATH
CCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCHHHHHHCCCCCCCCCCCEE
YPLRFTVKGSRYISGQRKGQILTEIWQ
CCEEEEECCCEEECCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA