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The map label for this gene is nahR [H]

Identifier: 116689976

GI number: 116689976

Start: 2173681

End: 2174610

Strand: Direct

Name: nahR [H]

Synonym: Bcen2424_1955

Alternate gene names: 116689976

Gene position: 2173681-2174610 (Clockwise)

Preceding gene: 116689975

Following gene: 116689978

Centisome position: 62.39

GC content: 65.38

Gene sequence:

>930_bases
ATGAGTCAGCAACGCGAGGCGATCGACACGTACCTCTTGCGCGTCTTGCACACCTTGTTGATGGAGCGCAGCGTCACGCG
CGCGGCCGTCAAACTGAACCAGTCGCAACCGGCGATCAGTGCCGCGCTGCGGCGCCTGCGCGACATCACCGGCGATCCGC
TGCTGGTGCGCGGCAAATCCGGCATGGTGCCGACCGAATACGGGCTGCGCCTGCTCGAGCCCGTGCAGAACGCGCTGCGC
GAAATCGAGCGCATCAAGTTCCAGCAGCACAACTTCGACCCGGCCACGTCGATCCGCTGCTACCGGATCGGCTGCCCCGA
CTACCTGAACGTGCTGTTCGTGCCGACCGTCGTCGAGCGCTTTCGCCTGGCCGCGCCGAACGCAACGCTAGAGTTTCATT
CGCTCGGCCCCGCGTTCGACTACGAGCTCGCGCTGGAAGACGGCAAGCTCGACATCGTCGTCGGCAACTGGCCCGAGCCG
CCGGAGCAACTGCATCTGTCGAACCTGTTCGTCGATGAAATCGTCTGCCTGATGAGCAACACGCACCCGTTCGCGAAACG
CGGCGGGCTCACGCTCGACCAGTACCTGAACGCGCCGCATCTCGCGCCGACGCCGTACTCGGTCGGCCAGCGCGGCGCGA
TCGACGTGCATCTCGCGCGCGAACGGCTCAAGCGCCACGTGGTCGTCACGCTGCCGTACTTCAACCTTGCGCCGTACGTG
CTCGTGAAGTCGGACCTGATCTTCACGACCACGCGGCTATTCGCCGATCACTACGCGAAGTTCCTGCCGCTGTCCGTCGT
GCCGGCGCCGCTCGACTTCCCGCCGATGCAGTACTACCAGCTGTGGCACGAACGCTGCCATTACTCCGACGAAGTGCGCT
GGCTGCGCAGCCTCGTCGCCGAAGCCACCCGTACGCTGATCGAGGCGTAG

Upstream 100 bases:

>100_bases
CCTGCGGGTATCCATCTCTTGACGCTGATTTTCGTTCATATTAAAAACGATATACCCACCCCACCCCTCGATCAGCCCAG
CCATATAAACCGGAGATAAC

Downstream 100 bases:

>100_bases
TCGCATACGGCGCACCACGCGTGCGCCGGTCGCGCCGTTACGCGCGACCACGGCGCGTTGCGCGACGGGTGGTGGCCACA
ATGGCCGCGCCCCGCTGCGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSQQREAIDTYLLRVLHTLLMERSVTRAAVKLNQSQPAISAALRRLRDITGDPLLVRGKSGMVPTEYGLRLLEPVQNALR
EIERIKFQQHNFDPATSIRCYRIGCPDYLNVLFVPTVVERFRLAAPNATLEFHSLGPAFDYELALEDGKLDIVVGNWPEP
PEQLHLSNLFVDEIVCLMSNTHPFAKRGGLTLDQYLNAPHLAPTPYSVGQRGAIDVHLARERLKRHVVVTLPYFNLAPYV
LVKSDLIFTTTRLFADHYAKFLPLSVVPAPLDFPPMQYYQLWHERCHYSDEVRWLRSLVAEATRTLIEA

Sequences:

>Translated_309_residues
MSQQREAIDTYLLRVLHTLLMERSVTRAAVKLNQSQPAISAALRRLRDITGDPLLVRGKSGMVPTEYGLRLLEPVQNALR
EIERIKFQQHNFDPATSIRCYRIGCPDYLNVLFVPTVVERFRLAAPNATLEFHSLGPAFDYELALEDGKLDIVVGNWPEP
PEQLHLSNLFVDEIVCLMSNTHPFAKRGGLTLDQYLNAPHLAPTPYSVGQRGAIDVHLARERLKRHVVVTLPYFNLAPYV
LVKSDLIFTTTRLFADHYAKFLPLSVVPAPLDFPPMQYYQLWHERCHYSDEVRWLRSLVAEATRTLIEA
>Mature_308_residues
SQQREAIDTYLLRVLHTLLMERSVTRAAVKLNQSQPAISAALRRLRDITGDPLLVRGKSGMVPTEYGLRLLEPVQNALRE
IERIKFQQHNFDPATSIRCYRIGCPDYLNVLFVPTVVERFRLAAPNATLEFHSLGPAFDYELALEDGKLDIVVGNWPEPP
EQLHLSNLFVDEIVCLMSNTHPFAKRGGLTLDQYLNAPHLAPTPYSVGQRGAIDVHLARERLKRHVVVTLPYFNLAPYVL
VKSDLIFTTTRLFADHYAKFLPLSVVPAPLDFPPMQYYQLWHERCHYSDEVRWLRSLVAEATRTLIEA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=301, Percent_Identity=26.578073089701, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790147, Length=298, Percent_Identity=23.489932885906, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788481, Length=290, Percent_Identity=28.2758620689655, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788887, Length=223, Percent_Identity=27.3542600896861, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35296; Mature: 35165

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQREAIDTYLLRVLHTLLMERSVTRAAVKLNQSQPAISAALRRLRDITGDPLLVRGKS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCC
GMVPTEYGLRLLEPVQNALREIERIKFQQHNFDPATSIRCYRIGCPDYLNVLFVPTVVER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
FRLAAPNATLEFHSLGPAFDYELALEDGKLDIVVGNWPEPPEQLHLSNLFVDEIVCLMSN
HHHCCCCCEEEECCCCCCCCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
THPFAKRGGLTLDQYLNAPHLAPTPYSVGQRGAIDVHLARERLKRHVVVTLPYFNLAPYV
CCCHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCE
LVKSDLIFTTTRLFADHYAKFLPLSVVPAPLDFPPMQYYQLWHERCHYSDEVRWLRSLVA
EEECCHHHHHHHHHHHHHHHHCCHHEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
EATRTLIEA
HHHHHHHCC
>Mature Secondary Structure 
SQQREAIDTYLLRVLHTLLMERSVTRAAVKLNQSQPAISAALRRLRDITGDPLLVRGKS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCC
GMVPTEYGLRLLEPVQNALREIERIKFQQHNFDPATSIRCYRIGCPDYLNVLFVPTVVER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
FRLAAPNATLEFHSLGPAFDYELALEDGKLDIVVGNWPEPPEQLHLSNLFVDEIVCLMSN
HHHCCCCCEEEECCCCCCCCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
THPFAKRGGLTLDQYLNAPHLAPTPYSVGQRGAIDVHLARERLKRHVVVTLPYFNLAPYV
CCCHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCE
LVKSDLIFTTTRLFADHYAKFLPLSVVPAPLDFPPMQYYQLWHERCHYSDEVRWLRSLVA
EEECCHHHHHHHHHHHHHHHHCCHHEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
EATRTLIEA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]