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The map label for this gene is arnB [H]

Identifier: 116689880

GI number: 116689880

Start: 2064407

End: 2065621

Strand: Direct

Name: arnB [H]

Synonym: Bcen2424_1859

Alternate gene names: 116689880

Gene position: 2064407-2065621 (Clockwise)

Preceding gene: 116689879

Following gene: 116689881

Centisome position: 59.26

GC content: 66.01

Gene sequence:

>1215_bases
ATGCCGGTTTCGGGCGGATCGCCCGACCCTTTTATTACACGCCATTACAGGCCCAACGCGTTCATGAGCCAGACTACCGC
TCCGTTTCTGCCGTTCACCCGCCCCGAGATCGATGAGGAAACCATCCAGGGCGTCGTCGACGTGTTGCGCTCGGGCTGGA
TCACCACCGGCCCGCAGTGCCAGAAATTCGAGGCCGCGCTGTCCGAGTACTGCGGCGGCCGTCCGGTTCGCGCCTTCAAT
TCGGGCACCTGTACGCTCGAGATCGGCCTGCGCATCGCCGGCGTCGGCCCCGGCGACGAGGTGATCACGACGCCGGCGTC
GTGGGTCTCGACCAGCAACGTGATCATCGAGACGGGCGCGACGCCCGTGTTCGCGGACATCGACCCCGTCACGCGCAACA
TCGACCTCGACAAGCTCGAGCAGGCGATCACGCCGCGCACCAAGGCGATCATCCCCGTGTTCCTGTCCGGCCTGCCGGTC
GACATGGACCGCCTGTACGCGATCGCCCGCGCGCACAAGCTGCGCGTGATCGAGGATGCCGCGCAGGCGTTCGGCTCGAC
GTGGAACGGCAAGCGCATCGGCGCGATCGGCGACATCGTGTCGTTCAGCTTCCACGCGAACAAGAACCTGACGACGATCG
AAGGCGGCGCGCTCGTGCTGAACAACGAGGACGAAGCGGCGCTCGCGCAGAAGTATCGGCTGCAGGGCATCACGCGCACC
GGCTTCGACGGGATGGACTGCGACGTGCTCGGCGGCAAGTACAACCTGACCGACGTCGCCGCGCGCGTCGGCCTCGGCCA
GTTGCCGCACATCGAGCGCTTCACCGCGCAGCGCCGCGCGCTCGCCCGTGCGTATTTCGCCGCGTTCGACGGCGGCGCGG
CCGTGAAGCTGGGCCTCGGCCTGCCGGTCGCCGAATTCGAGAACGGCAACTGGCACATGTTCCTGGTCACGCTGCCGCTC
GAGCGGCTGACGATCACGCGCGCCGAATTCATGGCGCAAATGAAGGAACGCGGCATCGGCACCGGCATCCACTACCCGGC
GATCCATCTTTTCACGCTGTATCGTGCGCGCGGCTTCAAGGAGGGCATGTTCCCCCACGCCGAACGGTACGGCGCGTCGA
CCGTCACGCTGCCGCTGTTTACGCAGATGACGGAAGGCGACGTGCGTCGCGTGGTCGACGCCGTCAATCAGATTTGCGAA
CAATACGGAAAATAA

Upstream 100 bases:

>100_bases
CTGATCGGTGTGCTCGTGCTGGCGCGCAGCTGAGCGCGGCCCGCGCCGTTAAGCGTCCGCCTACAAAAAATCACGGTACG
AATCCGCCAACCGGTGTTTA

Downstream 100 bases:

>100_bases
GCGTACATGAGTCACCTTGAAGCACGCGCCGGGCATCCGGGCGCCGCGCATCTGGACGCCGGCCGGCCGGAAGTGTCGGT
CATCATCCCCGTGTACAACG

Product: DegT/DnrJ/EryC1/StrS aminotransferase

Products: NA

Alternate protein names: UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase; UDP-Ara4O aminotransferase; UDP-4-amino-4-deoxy-L-arabinose aminotransferase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MPVSGGSPDPFITRHYRPNAFMSQTTAPFLPFTRPEIDEETIQGVVDVLRSGWITTGPQCQKFEAALSEYCGGRPVRAFN
SGTCTLEIGLRIAGVGPGDEVITTPASWVSTSNVIIETGATPVFADIDPVTRNIDLDKLEQAITPRTKAIIPVFLSGLPV
DMDRLYAIARAHKLRVIEDAAQAFGSTWNGKRIGAIGDIVSFSFHANKNLTTIEGGALVLNNEDEAALAQKYRLQGITRT
GFDGMDCDVLGGKYNLTDVAARVGLGQLPHIERFTAQRRALARAYFAAFDGGAAVKLGLGLPVAEFENGNWHMFLVTLPL
ERLTITRAEFMAQMKERGIGTGIHYPAIHLFTLYRARGFKEGMFPHAERYGASTVTLPLFTQMTEGDVRRVVDAVNQICE
QYGK

Sequences:

>Translated_404_residues
MPVSGGSPDPFITRHYRPNAFMSQTTAPFLPFTRPEIDEETIQGVVDVLRSGWITTGPQCQKFEAALSEYCGGRPVRAFN
SGTCTLEIGLRIAGVGPGDEVITTPASWVSTSNVIIETGATPVFADIDPVTRNIDLDKLEQAITPRTKAIIPVFLSGLPV
DMDRLYAIARAHKLRVIEDAAQAFGSTWNGKRIGAIGDIVSFSFHANKNLTTIEGGALVLNNEDEAALAQKYRLQGITRT
GFDGMDCDVLGGKYNLTDVAARVGLGQLPHIERFTAQRRALARAYFAAFDGGAAVKLGLGLPVAEFENGNWHMFLVTLPL
ERLTITRAEFMAQMKERGIGTGIHYPAIHLFTLYRARGFKEGMFPHAERYGASTVTLPLFTQMTEGDVRRVVDAVNQICE
QYGK
>Mature_403_residues
PVSGGSPDPFITRHYRPNAFMSQTTAPFLPFTRPEIDEETIQGVVDVLRSGWITTGPQCQKFEAALSEYCGGRPVRAFNS
GTCTLEIGLRIAGVGPGDEVITTPASWVSTSNVIIETGATPVFADIDPVTRNIDLDKLEQAITPRTKAIIPVFLSGLPVD
MDRLYAIARAHKLRVIEDAAQAFGSTWNGKRIGAIGDIVSFSFHANKNLTTIEGGALVLNNEDEAALAQKYRLQGITRTG
FDGMDCDVLGGKYNLTDVAARVGLGQLPHIERFTAQRRALARAYFAAFDGGAAVKLGLGLPVAEFENGNWHMFLVTLPLE
RLTITRAEFMAQMKERGIGTGIHYPAIHLFTLYRARGFKEGMFPHAERYGASTVTLPLFTQMTEGDVRRVVDAVNQICEQ
YGK

Specific function: Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family. ArnB subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=384, Percent_Identity=40.8854166666667, Blast_Score=254, Evalue=7e-69,
Organism=Escherichia coli, GI2367285, Length=373, Percent_Identity=31.3672922252011, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022850
- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: =2.6.1.87 [H]

Molecular weight: Translated: 44128; Mature: 43997

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVSGGSPDPFITRHYRPNAFMSQTTAPFLPFTRPEIDEETIQGVVDVLRSGWITTGPQC
CCCCCCCCCCCEEECCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCH
QKFEAALSEYCGGRPVRAFNSGTCTLEIGLRIAGVGPGDEVITTPASWVSTSNVIIETGA
HHHHHHHHHHCCCCCEEEECCCEEEEEEEEEEEECCCCCCEEECCHHHHCCCCEEEECCC
TPVFADIDPVTRNIDLDKLEQAITPRTKAIIPVFLSGLPVDMDRLYAIARAHKLRVIEDA
CCEEECCCCHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
AQAFGSTWNGKRIGAIGDIVSFSFHANKNLTTIEGGALVLNNEDEAALAQKYRLQGITRT
HHHCCCCCCCCCCCCHHHHHEEEEECCCCCEEEECCEEEECCCCHHHHHHHHHHCCCCCC
GFDGMDCDVLGGKYNLTDVAARVGLGQLPHIERFTAQRRALARAYFAAFDGGAAVKLGLG
CCCCCCEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
LPVAEFENGNWHMFLVTLPLERLTITRAEFMAQMKERGIGTGIHYPAIHLFTLYRARGFK
CCHHEECCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCC
EGMFPHAERYGASTVTLPLFTQMTEGDVRRVVDAVNQICEQYGK
CCCCCCHHHCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PVSGGSPDPFITRHYRPNAFMSQTTAPFLPFTRPEIDEETIQGVVDVLRSGWITTGPQC
CCCCCCCCCCEEECCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCH
QKFEAALSEYCGGRPVRAFNSGTCTLEIGLRIAGVGPGDEVITTPASWVSTSNVIIETGA
HHHHHHHHHHCCCCCEEEECCCEEEEEEEEEEEECCCCCCEEECCHHHHCCCCEEEECCC
TPVFADIDPVTRNIDLDKLEQAITPRTKAIIPVFLSGLPVDMDRLYAIARAHKLRVIEDA
CCEEECCCCHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
AQAFGSTWNGKRIGAIGDIVSFSFHANKNLTTIEGGALVLNNEDEAALAQKYRLQGITRT
HHHCCCCCCCCCCCCHHHHHEEEEECCCCCEEEECCEEEECCCCHHHHHHHHHHCCCCCC
GFDGMDCDVLGGKYNLTDVAARVGLGQLPHIERFTAQRRALARAYFAAFDGGAAVKLGLG
CCCCCCEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
LPVAEFENGNWHMFLVTLPLERLTITRAEFMAQMKERGIGTGIHYPAIHLFTLYRARGFK
CCHHEECCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCC
EGMFPHAERYGASTVTLPLFTQMTEGDVRRVVDAVNQICEQYGK
CCCCCCHHHCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA