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The map label for this gene is emrY [H]

Identifier: 116689852

GI number: 116689852

Start: 2033771

End: 2035327

Strand: Direct

Name: emrY [H]

Synonym: Bcen2424_1831

Alternate gene names: 116689852

Gene position: 2033771-2035327 (Clockwise)

Preceding gene: 116689851

Following gene: 116689853

Centisome position: 58.38

GC content: 67.12

Gene sequence:

>1557_bases
ATGAACGCGGTGCCGGGCCGGCCGCCGCTGTGGAGCCGCGCAAACCTGCGGGGGGACCTGTTCCCGTGGGCACTCGCGCT
CGTCACCGGCATCGACTACTTCGACAACGCCGTCTTCTCGTTCTTCGCGAGCTACATCGCGGGCGGCATCAACGCGTCGC
CCGACGAACTGGTGTGGTCGTCGAGCGCGTACGCGGTCACGGCCGTGCTCGGCATCCTGCAGCAGCAATGGTGGGTCGAC
CGGCTCGGCCATCGCCGCTACGTCGCGGGCTGCATGCTGATGTTCTCGTTCGGCGCGATCGCGGCGGCGCTGGCCGACAC
GTCGCTGGAGCTCGCGTTCGCGCGCGGCTTCCAGGGCTATTTCATCGGCCCGATGATGGGCGCGTGCCGGATCCTGATCC
AGATCAGCTTCAAGCCGCAGGAGCGGCCGCCCGCGACGCGCGCGTTCCTGATCATGATCCTGCTCGGCAGCGCGCTCGCG
CCGATCGTCGGCGGGCTGCTGGTCGCGCATTCGACGTGGCGCGCACTGTTCGCGTGCACGGCGCCGGCCGGCATCGCGTT
CGCGATCCTCGCGTTGCTCACGCTGCCCGATTCCGGCCGCACGCCGGACGACGAACGCGGTTCCGGACATTTCTGGCCGT
ACGTCGTGTTCGCGCTCGCGCAAGGGGCGCTGCAGATCGTGCTGCAACAGGTGCATTACCAGCTCTACAGCGGCTCGCCG
ATGCTGATCATGCTGACGTTCGCCGGGCTCGGCGCGCTCGCGTGGTTCGCGTATCACCAGTGGCACCATCCGACGCCGCT
CGTGCGGCTGCATGCGTTTCGCGAGCGGACGTTCCAGGTCGGGCTGCTGCTCTACATGTTCTATTACTACGAGACGACGG
GCTTCAGTTACCTGACGTCCCGGTTACTCGAGGGCGGGCTCGGCTATCCGGTCGAGAATGCCGGGCGCCTGGTCGGCACG
ATGTCGCTGATCTCGGCCACCGCGCTGTTCGCCTACCTGCGCTACGCGAAATTCGTCGCGCACAAGAAGTGGTTCGTCGT
GCCCGGGTTCGCGATCGCCGTCACGGCCGCGCTGTGGATGACCCGGATGACGCCGCAGATCGGCGAAGCCGCGCTGATCG
TCCCGTTGCTGCTGCGCGGGCTGCTGCTGCTCTTCATCGTGCTGCCGGTCGCGAATCTCACGTTCCGGATCTTCGCGATC
GACGAATACACGCACGGCTACCGGCTGAAGAACATCGTGCGGCAACTGACGATCTCGTTCGCGACGTCGTCGGTGATCAT
CGTCGAGCAGCACCGCGTGGCCGTGCACCAGACGCGGCTCGTCGAGCGCGCGAGCGTGTTCGACCCGCTGTTCCAGCAGA
CCGTCGATGCACTGACGCGCAGCTATGCGGCCGCCGGCCACGCGCTGAACGACGCGCACGGCCTCGCGATCGCGTCGATC
GCGCGGATGGTCGCGCAACAGGCGTCGTTCCTCGCGTCGCTCGACGGTTTTTACTTCCTCGCGGGCGTCGCGCTCGTCGG
CGGTCTCTTCGCGGCATGGCAAAAACAGATCGATTGA

Upstream 100 bases:

>100_bases
TCGACTACGTCGAGCGGCGCCTCGCCGGCGAAAACGCGGATGAACTGATCGCGCAGCGGCGGGCCGAAGCCGGCGCGCGG
CGCGCCCGCAAGGATCGCGA

Downstream 100 bases:

>100_bases
GTTAAAAGACAGGCTTTGGATTTTCGTCCGCCGCCTCCATGCTTTCGAAACTGACCCGCTGGTTCGACGATCGCCGCCGC
GACCGCGCGCTGCGCAGCCA

Product: major facilitator transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MNAVPGRPPLWSRANLRGDLFPWALALVTGIDYFDNAVFSFFASYIAGGINASPDELVWSSSAYAVTAVLGILQQQWWVD
RLGHRRYVAGCMLMFSFGAIAAALADTSLELAFARGFQGYFIGPMMGACRILIQISFKPQERPPATRAFLIMILLGSALA
PIVGGLLVAHSTWRALFACTAPAGIAFAILALLTLPDSGRTPDDERGSGHFWPYVVFALAQGALQIVLQQVHYQLYSGSP
MLIMLTFAGLGALAWFAYHQWHHPTPLVRLHAFRERTFQVGLLLYMFYYYETTGFSYLTSRLLEGGLGYPVENAGRLVGT
MSLISATALFAYLRYAKFVAHKKWFVVPGFAIAVTAALWMTRMTPQIGEAALIVPLLLRGLLLLFIVLPVANLTFRIFAI
DEYTHGYRLKNIVRQLTISFATSSVIIVEQHRVAVHQTRLVERASVFDPLFQQTVDALTRSYAAAGHALNDAHGLAIASI
ARMVAQQASFLASLDGFYFLAGVALVGGLFAAWQKQID

Sequences:

>Translated_518_residues
MNAVPGRPPLWSRANLRGDLFPWALALVTGIDYFDNAVFSFFASYIAGGINASPDELVWSSSAYAVTAVLGILQQQWWVD
RLGHRRYVAGCMLMFSFGAIAAALADTSLELAFARGFQGYFIGPMMGACRILIQISFKPQERPPATRAFLIMILLGSALA
PIVGGLLVAHSTWRALFACTAPAGIAFAILALLTLPDSGRTPDDERGSGHFWPYVVFALAQGALQIVLQQVHYQLYSGSP
MLIMLTFAGLGALAWFAYHQWHHPTPLVRLHAFRERTFQVGLLLYMFYYYETTGFSYLTSRLLEGGLGYPVENAGRLVGT
MSLISATALFAYLRYAKFVAHKKWFVVPGFAIAVTAALWMTRMTPQIGEAALIVPLLLRGLLLLFIVLPVANLTFRIFAI
DEYTHGYRLKNIVRQLTISFATSSVIIVEQHRVAVHQTRLVERASVFDPLFQQTVDALTRSYAAAGHALNDAHGLAIASI
ARMVAQQASFLASLDGFYFLAGVALVGGLFAAWQKQID
>Mature_518_residues
MNAVPGRPPLWSRANLRGDLFPWALALVTGIDYFDNAVFSFFASYIAGGINASPDELVWSSSAYAVTAVLGILQQQWWVD
RLGHRRYVAGCMLMFSFGAIAAALADTSLELAFARGFQGYFIGPMMGACRILIQISFKPQERPPATRAFLIMILLGSALA
PIVGGLLVAHSTWRALFACTAPAGIAFAILALLTLPDSGRTPDDERGSGHFWPYVVFALAQGALQIVLQQVHYQLYSGSP
MLIMLTFAGLGALAWFAYHQWHHPTPLVRLHAFRERTFQVGLLLYMFYYYETTGFSYLTSRLLEGGLGYPVENAGRLVGT
MSLISATALFAYLRYAKFVAHKKWFVVPGFAIAVTAALWMTRMTPQIGEAALIVPLLLRGLLLLFIVLPVANLTFRIFAI
DEYTHGYRLKNIVRQLTISFATSSVIIVEQHRVAVHQTRLVERASVFDPLFQQTVDALTRSYAAAGHALNDAHGLAIASI
ARMVAQQASFLASLDGFYFLAGVALVGGLFAAWQKQID

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1788710, Length=455, Percent_Identity=22.4175824175824, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1789042, Length=488, Percent_Identity=21.7213114754098, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1790195, Length=432, Percent_Identity=23.6111111111111, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87081983, Length=265, Percent_Identity=24.5283018867925, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 56947; Mature: 56947

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVPGRPPLWSRANLRGDLFPWALALVTGIDYFDNAVFSFFASYIAGGINASPDELVWS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEC
SSAYAVTAVLGILQQQWWVDRLGHRRYVAGCMLMFSFGAIAAALADTSLELAFARGFQGY
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
FIGPMMGACRILIQISFKPQERPPATRAFLIMILLGSALAPIVGGLLVAHSTWRALFACT
EHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APAGIAFAILALLTLPDSGRTPDDERGSGHFWPYVVFALAQGALQIVLQQVHYQLYSGSP
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MLIMLTFAGLGALAWFAYHQWHHPTPLVRLHAFRERTFQVGLLLYMFYYYETTGFSYLTS
CEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RLLEGGLGYPVENAGRLVGTMSLISATALFAYLRYAKFVAHKKWFVVPGFAIAVTAALWM
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHH
TRMTPQIGEAALIVPLLLRGLLLLFIVLPVANLTFRIFAIDEYTHGYRLKNIVRQLTISF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHH
ATSSVIIVEQHRVAVHQTRLVERASVFDPLFQQTVDALTRSYAAAGHALNDAHGLAIASI
HCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ARMVAQQASFLASLDGFYFLAGVALVGGLFAAWQKQID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAVPGRPPLWSRANLRGDLFPWALALVTGIDYFDNAVFSFFASYIAGGINASPDELVWS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEC
SSAYAVTAVLGILQQQWWVDRLGHRRYVAGCMLMFSFGAIAAALADTSLELAFARGFQGY
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
FIGPMMGACRILIQISFKPQERPPATRAFLIMILLGSALAPIVGGLLVAHSTWRALFACT
EHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APAGIAFAILALLTLPDSGRTPDDERGSGHFWPYVVFALAQGALQIVLQQVHYQLYSGSP
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MLIMLTFAGLGALAWFAYHQWHHPTPLVRLHAFRERTFQVGLLLYMFYYYETTGFSYLTS
CEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RLLEGGLGYPVENAGRLVGTMSLISATALFAYLRYAKFVAHKKWFVVPGFAIAVTAALWM
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHH
TRMTPQIGEAALIVPLLLRGLLLLFIVLPVANLTFRIFAIDEYTHGYRLKNIVRQLTISF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHH
ATSSVIIVEQHRVAVHQTRLVERASVFDPLFQQTVDALTRSYAAAGHALNDAHGLAIASI
HCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ARMVAQQASFLASLDGFYFLAGVALVGGLFAAWQKQID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]