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The map label for this gene is lrp [C]

Identifier: 116689745

GI number: 116689745

Start: 1917908

End: 1918372

Strand: Reverse

Name: lrp [C]

Synonym: Bcen2424_1724

Alternate gene names: 116689745

Gene position: 1918372-1917908 (Counterclockwise)

Preceding gene: 116689748

Following gene: 116689744

Centisome position: 55.06

GC content: 68.17

Gene sequence:

>465_bases
ATGCGCCCACCCCGCCTCGACCAACTCGACGATCTCGACCGGCAACTCGTCGCGCTGCTGCAAGCCGATGCGCGCGCCAG
CGTCGCGGATCTCGCGCGCCAGCTCGACGTCGCGCGCACGACGGTCGTCGCGCGCATCGCGCGGCTCGAACGCACGAACG
TGATCGCCGGGTACAGCGTGCGGCTCGGGCAGGACGTGCTGGACGCCAGCATCTACGCGTACGTCGGCATCATCCTCACG
CCGAAATTCGGCAAGGACGTCTTGCGCAAGCTCGACCGGATGCCGGAAGTCCAGTTGCTGTGCGCGGTGAGCGGCGAGTA
CGACTACGTCGCGTGGCTGCGCGCCGATTCGCCGGAACGGCTCAACGACCTGCTCGACCAGATCGGCACGCTCGAAGGCG
TCGAGCGCACGACGACGTCGATCATCCTGTCGCGCAAGATCGACCGCGGGACGATCGGCGGCTGA

Upstream 100 bases:

>100_bases
AAGCTGCGAATCCGGGCCGTGCCGGTTGGGCGCGCCGGCGATCGGCGCTATCATCGCGTCACTTTCCACTCCGCCGGCAC
ATGCGTACCGGCCCAGCGTC

Downstream 100 bases:

>100_bases
GCCGTTGCATGTGGCACCGCACATGACGGACGGCGCATGCGCGGCGCCGGTTTCGTTGCGTCACGGGTGTCTGGATTAAC
GGCGGGTAGATGCCCGGCCG

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MRPPRLDQLDDLDRQLVALLQADARASVADLARQLDVARTTVVARIARLERTNVIAGYSVRLGQDVLDASIYAYVGIILT
PKFGKDVLRKLDRMPEVQLLCAVSGEYDYVAWLRADSPERLNDLLDQIGTLEGVERTTTSIILSRKIDRGTIGG

Sequences:

>Translated_154_residues
MRPPRLDQLDDLDRQLVALLQADARASVADLARQLDVARTTVVARIARLERTNVIAGYSVRLGQDVLDASIYAYVGIILT
PKFGKDVLRKLDRMPEVQLLCAVSGEYDYVAWLRADSPERLNDLLDQIGTLEGVERTTTSIILSRKIDRGTIGG
>Mature_154_residues
MRPPRLDQLDDLDRQLVALLQADARASVADLARQLDVARTTVVARIARLERTNVIAGYSVRLGQDVLDASIYAYVGIILT
PKFGKDVLRKLDRMPEVQLLCAVSGEYDYVAWLRADSPERLNDLLDQIGTLEGVERTTTSIILSRKIDRGTIGG

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=141, Percent_Identity=31.2056737588652, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1790182, Length=145, Percent_Identity=28.9655172413793, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 17093; Mature: 17093

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPPRLDQLDDLDRQLVALLQADARASVADLARQLDVARTTVVARIARLERTNVIAGYSV
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCHH
RLGQDVLDASIYAYVGIILTPKFGKDVLRKLDRMPEVQLLCAVSGEYDYVAWLRADSPER
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCHHH
LNDLLDQIGTLEGVERTTTSIILSRKIDRGTIGG
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRPPRLDQLDDLDRQLVALLQADARASVADLARQLDVARTTVVARIARLERTNVIAGYSV
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCHH
RLGQDVLDASIYAYVGIILTPKFGKDVLRKLDRMPEVQLLCAVSGEYDYVAWLRADSPER
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCHHH
LNDLLDQIGTLEGVERTTTSIILSRKIDRGTIGG
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA