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The map label for this gene is cobJ [H]

Identifier: 116689693

GI number: 116689693

Start: 1857489

End: 1859198

Strand: Reverse

Name: cobJ [H]

Synonym: Bcen2424_1671

Alternate gene names: 116689693

Gene position: 1859198-1857489 (Counterclockwise)

Preceding gene: 116689694

Following gene: 116689692

Centisome position: 53.37

GC content: 72.34

Gene sequence:

>1710_bases
ATGACGACCCCGCCCGCGATCGTGATTCTCGGCGCGGGCGCGCTCGATACCGCGCGACGCATCCAGGCGCGTTACCCGGG
CGCCCGGGTGCACGGTCTCGCATCGCGCGTCGACGCCGACGTGCCGTTCGACGAACTCGGCGCGCACCTGCGCGAACTCT
ATGCGCGCGGCCAGCCGATCGTCGCGCTGTGCGCGGCCGGCATCGTGATCCGCTGCCTCGCGCCCGCGCTCGCCGACAAG
GGCGTCGAGCCGCCGGTGCTCGCGGTCGCGGAGGACGGCTCGGCCGTCGTGCCGCTGCTCGGCGGACTGACCGGCGTCAA
CGTGATCGCGCGCGAAATCGCAGAATGCGTCGGCGTCGCGCCGGCGATCACGACGAGCGGCGAACTGCGCTTCGGCGCGT
GCGTGCTCAATCCACCGGAAGGCTATGCGCTCGCCGATCTCGCGCAGGGCAAGCGCTTCGTGTCCGACCTGCTCGCGGGT
GCGTCGACGCGCGTCGACGGCGCGGCGCCGTGGCTCGACGACGTCGCGCTGCCGCGCGATGCCGCGGCCGCGCACGCGAT
TCGCGTGACGCCCGATGCGTGGCGCGGCGCGCGCGACGAGCTCGTGATTCATCCGCGCAGCGTGGTGGTCGGTGTTGCCG
CGGATGCCGTGCATACAGGCGAAGCGCTTGCGGCGCGCATCGAAGCCATGCTCGACGCACAGGGCCTCGCACGGCTGGCG
CTCGCGGCCATCGTCGCGCCGGCGTCGGCGATCGGCGAACCCGCATTGGAAGAAGCGGCGAGCACGCTCGACGTGCCGCT
GCGTTTCGTCGATGGCGATCGCGACGAGCCTGCCGACGCCAGCACGCTGCTCGGCCGCGCATTGCGCGTCACCCACACGC
TGCGTGAAGAATCTAACGGTCTCGCGTGCGCGGTCGCGTCGCAGCCGGTCGACCCCGCCACGCTCGGCCGCGCGTGCGGC
CGCCTGACGGTGCTCGGTCTCGGCCCGGGCGGCGCCGCATGGCTCACGCCGGCCGCGCGCGCGGCGCTCGCGGACGCGAC
CGACATCCTCGGCTATACGACCTACGTGAACATGGCCGGCCCGTTTCGGGCAGACCAGCGCGTGCACGGCACCGACAATC
GCGAGGAAATGCAGCGCGCGCGCCATGCGTTCGAACTGGCGGCCGAGGGCCGGCGCGTCGCGGTCGTATCGTCGGGCGAC
CCAGGCGTCTTCGCGATGGCCGCGGCCGTGCTCGAAGCGCTCGACGAAGCGCGCGACCCGCAATGGGCCGCGGTCGACCT
GCGCGTGGAGCCCGGCATCTCGGCGTCGCTCGCCACGGCCGCGCAGGCCGGCGCACCGCTCGGTCACGATTTCTGCGCGA
TCTCGCTGTCGGATAACCTGAAGCCGTGGGGCGTGATCGAGACGCGCCTGCAACACGCGGCGCAAGCCGATCTCGTGATG
GCGTTCTACAACCCGATTTCGCGCGCGCGGCCGTGGCAGCTCGACCGTGCGCTCGACATCGTGCGCGCGCATCGCGCGGC
CGATACGGTGGTCGTGCTCGGCCGCGACATCGGCCGACCGGGCGCGACGCTTTCGACGACGACCCTCGGCGCGCTGCGCG
GCGAGCAGGTCGACATGCGCACGATGGTGATCGTCGGCTCGTCGACGACGCGACGTTTCGCGATCGGCAACGCACGCGAA
TGGGTCTATACGCCGCGCTGGTATTGCTGA

Upstream 100 bases:

>100_bases
CGACGATGGCGAACCAGCGCATCGTTCCGCTCGACGAGGTCGATCCGATGGCGTCGCCGTATTTCTCGCTGCTCGTCGTG
CCGGGGGAAAAATGGCAAGG

Downstream 100 bases:

>100_bases
ACGCCGCGGCGCGCGCATCGAATCCGGCGGTGCTCACGTGAACGCGCGATGCGCGCGAGCCGTCAATCGGCATGCCGGTG
TATCACCAGGCTCCCTGGAA

Product: precorrin-3B C17-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase; Precorrin-3 methyltransferase [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MTTPPAIVILGAGALDTARRIQARYPGARVHGLASRVDADVPFDELGAHLRELYARGQPIVALCAAGIVIRCLAPALADK
GVEPPVLAVAEDGSAVVPLLGGLTGVNVIAREIAECVGVAPAITTSGELRFGACVLNPPEGYALADLAQGKRFVSDLLAG
ASTRVDGAAPWLDDVALPRDAAAAHAIRVTPDAWRGARDELVIHPRSVVVGVAADAVHTGEALAARIEAMLDAQGLARLA
LAAIVAPASAIGEPALEEAASTLDVPLRFVDGDRDEPADASTLLGRALRVTHTLREESNGLACAVASQPVDPATLGRACG
RLTVLGLGPGGAAWLTPAARAALADATDILGYTTYVNMAGPFRADQRVHGTDNREEMQRARHAFELAAEGRRVAVVSSGD
PGVFAMAAAVLEALDEARDPQWAAVDLRVEPGISASLATAAQAGAPLGHDFCAISLSDNLKPWGVIETRLQHAAQADLVM
AFYNPISRARPWQLDRALDIVRAHRAADTVVVLGRDIGRPGATLSTTTLGALRGEQVDMRTMVIVGSSTTRRFAIGNARE
WVYTPRWYC

Sequences:

>Translated_569_residues
MTTPPAIVILGAGALDTARRIQARYPGARVHGLASRVDADVPFDELGAHLRELYARGQPIVALCAAGIVIRCLAPALADK
GVEPPVLAVAEDGSAVVPLLGGLTGVNVIAREIAECVGVAPAITTSGELRFGACVLNPPEGYALADLAQGKRFVSDLLAG
ASTRVDGAAPWLDDVALPRDAAAAHAIRVTPDAWRGARDELVIHPRSVVVGVAADAVHTGEALAARIEAMLDAQGLARLA
LAAIVAPASAIGEPALEEAASTLDVPLRFVDGDRDEPADASTLLGRALRVTHTLREESNGLACAVASQPVDPATLGRACG
RLTVLGLGPGGAAWLTPAARAALADATDILGYTTYVNMAGPFRADQRVHGTDNREEMQRARHAFELAAEGRRVAVVSSGD
PGVFAMAAAVLEALDEARDPQWAAVDLRVEPGISASLATAAQAGAPLGHDFCAISLSDNLKPWGVIETRLQHAAQADLVM
AFYNPISRARPWQLDRALDIVRAHRAADTVVVLGRDIGRPGATLSTTTLGALRGEQVDMRTMVIVGSSTTRRFAIGNARE
WVYTPRWYC
>Mature_568_residues
TTPPAIVILGAGALDTARRIQARYPGARVHGLASRVDADVPFDELGAHLRELYARGQPIVALCAAGIVIRCLAPALADKG
VEPPVLAVAEDGSAVVPLLGGLTGVNVIAREIAECVGVAPAITTSGELRFGACVLNPPEGYALADLAQGKRFVSDLLAGA
STRVDGAAPWLDDVALPRDAAAAHAIRVTPDAWRGARDELVIHPRSVVVGVAADAVHTGEALAARIEAMLDAQGLARLAL
AAIVAPASAIGEPALEEAASTLDVPLRFVDGDRDEPADASTLLGRALRVTHTLREESNGLACAVASQPVDPATLGRACGR
LTVLGLGPGGAAWLTPAARAALADATDILGYTTYVNMAGPFRADQRVHGTDNREEMQRARHAFELAAEGRRVAVVSSGDP
GVFAMAAAVLEALDEARDPQWAAVDLRVEPGISASLATAAQAGAPLGHDFCAISLSDNLKPWGVIETRLQHAAQADLVMA
FYNPISRARPWQLDRALDIVRAHRAADTVVVLGRDIGRPGATLSTTTLGALRGEQVDMRTMVIVGSSTTRRFAIGNAREW
VYTPRWYC

Specific function: Methyltransferase that catalyzes the methylation of C-17 in precorrin-3B to form precorrin-4 [H]

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006363 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.131 [H]

Molecular weight: Translated: 59415; Mature: 59284

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPPAIVILGAGALDTARRIQARYPGARVHGLASRVDADVPFDELGAHLRELYARGQPI
CCCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCH
VALCAAGIVIRCLAPALADKGVEPPVLAVAEDGSAVVPLLGGLTGVNVIAREIAECVGVA
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEHHHHCCHHHHHHHHHHHHHHHCCC
PAITTSGELRFGACVLNPPEGYALADLAQGKRFVSDLLAGASTRVDGAAPWLDDVALPRD
CCEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCC
AAAAHAIRVTPDAWRGARDELVIHPRSVVVGVAADAVHTGEALAARIEAMLDAQGLARLA
HHHCCEEEECCHHHCCCCCCEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAIVAPASAIGEPALEEAASTLDVPLRFVDGDRDEPADASTLLGRALRVTHTLREESNG
HHHHHHCHHHCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
LACAVASQPVDPATLGRACGRLTVLGLGPGGAAWLTPAARAALADATDILGYTTYVNMAG
EEEEEECCCCCHHHHHHHCCCEEEEEECCCCCHHHCHHHHHHHHHHHHHHHEEEEEECCC
PFRADQRVHGTDNREEMQRARHAFELAAEGRRVAVVSSGDPGVFAMAAAVLEALDEARDP
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCC
QWAAVDLRVEPGISASLATAAQAGAPLGHDFCAISLSDNLKPWGVIETRLQHAAQADLVM
CEEEEEEEECCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
AFYNPISRARPWQLDRALDIVRAHRAADTVVVLGRDIGRPGATLSTTTLGALRGEQVDMR
HHHCHHHCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEHHHHHHHCCCCCCEE
TMVIVGSSTTRRFAIGNAREWVYTPRWYC
EEEEECCCCCEEEEECCCCCEEECCCCCC
>Mature Secondary Structure 
TTPPAIVILGAGALDTARRIQARYPGARVHGLASRVDADVPFDELGAHLRELYARGQPI
CCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCH
VALCAAGIVIRCLAPALADKGVEPPVLAVAEDGSAVVPLLGGLTGVNVIAREIAECVGVA
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEHHHHCCHHHHHHHHHHHHHHHCCC
PAITTSGELRFGACVLNPPEGYALADLAQGKRFVSDLLAGASTRVDGAAPWLDDVALPRD
CCEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCC
AAAAHAIRVTPDAWRGARDELVIHPRSVVVGVAADAVHTGEALAARIEAMLDAQGLARLA
HHHCCEEEECCHHHCCCCCCEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAIVAPASAIGEPALEEAASTLDVPLRFVDGDRDEPADASTLLGRALRVTHTLREESNG
HHHHHHCHHHCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
LACAVASQPVDPATLGRACGRLTVLGLGPGGAAWLTPAARAALADATDILGYTTYVNMAG
EEEEEECCCCCHHHHHHHCCCEEEEEECCCCCHHHCHHHHHHHHHHHHHHHEEEEEECCC
PFRADQRVHGTDNREEMQRARHAFELAAEGRRVAVVSSGDPGVFAMAAAVLEALDEARDP
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCC
QWAAVDLRVEPGISASLATAAQAGAPLGHDFCAISLSDNLKPWGVIETRLQHAAQADLVM
CEEEEEEEECCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
AFYNPISRARPWQLDRALDIVRAHRAADTVVVLGRDIGRPGATLSTTTLGALRGEQVDMR
HHHCHHHCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEHHHHHHHCCCCCCEE
TMVIVGSSTTRRFAIGNAREWVYTPRWYC
EEEEECCCCCEEEEECCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 8226690 [H]