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The map label for this gene is fimA [H]

Identifier: 116689648

GI number: 116689648

Start: 1793433

End: 1793945

Strand: Direct

Name: fimA [H]

Synonym: Bcen2424_1626

Alternate gene names: 116689648

Gene position: 1793433-1793945 (Clockwise)

Preceding gene: 116689647

Following gene: 116689649

Centisome position: 51.48

GC content: 65.89

Gene sequence:

>513_bases
ATGAAAAAATCCATCCTGTCCGCCGTCGCACTCGCGGCCCTGTCCACCTCGGCCTTCGCAGCGGGCACCGGCACGATCAA
CTTCACGGGCGAAATCGTCGCGGGCGCATGCGGCATCGACTCGAACTCGGTCAACCAGACCGTGCAGCTCGGCAAGGTGC
CGACCAACAAGTTCAAGCAAGCCGGCGACAAGTCGGACCCGGTGTCGTTCGACATCAAGCTGACCGACTGCGACACCAGC
ATCGCGCAGAACGCGTACTTCACGTTCACGGGCACGTCGAGCGCCGGCCAGCCGAAGCTGCTCGCCACGATCGGTTCGGC
CACCAACGTCGGCATCCGCCTGCAAGCCGCGTCGGGCGAATACCTCGACAACGGCGCCGAGCAGAAGGCCCCGACGCTGC
TGCAGAACGGCACGAACACCGCGCGCTTCGCCGCGATGTACGAAGCGACGGCAGCCGGCGTGACGCCGGGTACCGCCGAC
GGCGTCGCGAACTTCACGGTCCGCTACCAGTAA

Upstream 100 bases:

>100_bases
ATCTCGATAATGCCGCCTCGTGTCGGACGGGAGCCACCATGCGCTGCCGTTTGTGTCCGCCACGTCGTCCATTCCAATCG
CACTCCTTACGGGAAACGTC

Downstream 100 bases:

>100_bases
GCGTCCGTACCGGAGGAGGGATGCGTGCATCCCTTCCTCCTGCCTCTTTCCTCCCGTTTCCTTCTCCCTGGACTCCCGGT
AGCGCCGCGTGCGAATCAGA

Product: fimbrial protein

Products: NA

Alternate protein names: Type-1A pilin [H]

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MKKSILSAVALAALSTSAFAAGTGTINFTGEIVAGACGIDSNSVNQTVQLGKVPTNKFKQAGDKSDPVSFDIKLTDCDTS
IAQNAYFTFTGTSSAGQPKLLATIGSATNVGIRLQAASGEYLDNGAEQKAPTLLQNGTNTARFAAMYEATAAGVTPGTAD
GVANFTVRYQ

Sequences:

>Translated_170_residues
MKKSILSAVALAALSTSAFAAGTGTINFTGEIVAGACGIDSNSVNQTVQLGKVPTNKFKQAGDKSDPVSFDIKLTDCDTS
IAQNAYFTFTGTSSAGQPKLLATIGSATNVGIRLQAASGEYLDNGAEQKAPTLLQNGTNTARFAAMYEATAAGVTPGTAD
GVANFTVRYQ
>Mature_170_residues
MKKSILSAVALAALSTSAFAAGTGTINFTGEIVAGACGIDSNSVNQTVQLGKVPTNKFKQAGDKSDPVSFDIKLTDCDTS
IAQNAYFTFTGTSSAGQPKLLATIGSATNVGIRLQAASGEYLDNGAEQKAPTLLQNGTNTARFAAMYEATAAGVTPGTAD
GVANFTVRYQ

Specific function: Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs [H]

COG id: COG3539

COG function: function code NU; P pilus assembly protein, pilin FimA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family [H]

Homologues:

Organism=Escherichia coli, GI1790769, Length=154, Percent_Identity=44.8051948051948, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082421, Length=170, Percent_Identity=31.1764705882353, Blast_Score=82, Evalue=1e-17,
Organism=Escherichia coli, GI87081804, Length=185, Percent_Identity=31.8918918918919, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI87081753, Length=160, Percent_Identity=35.625, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1786746, Length=175, Percent_Identity=31.4285714285714, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789531, Length=194, Percent_Identity=31.4432989690722, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1789422, Length=185, Percent_Identity=32.972972972973, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966
- InterPro:   IPR000259
- InterPro:   IPR014779 [H]

Pfam domain/function: PF00419 Fimbrial [H]

EC number: NA

Molecular weight: Translated: 17340; Mature: 17340

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSILSAVALAALSTSAFAAGTGTINFTGEIVAGACGIDSNSVNQTVQLGKVPTNKFKQ
CCHHHHHHHHHHHHHCCCEECCCCEEEECCEEEEEECCCCCCCCCCEEEECCCCCHHHHH
AGDKSDPVSFDIKLTDCDTSIAQNAYFTFTGTSSAGQPKLLATIGSATNVGIRLQAASGE
CCCCCCCEEEEEEEECCCCHHHCCEEEEEECCCCCCCCEEEEEECCCCCCEEEEEECCCC
YLDNGAEQKAPTLLQNGTNTARFAAMYEATAAGVTPGTADGVANFTVRYQ
HHCCCCCCCCCHHHHCCCCCHHHEEEHHHHHCCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MKKSILSAVALAALSTSAFAAGTGTINFTGEIVAGACGIDSNSVNQTVQLGKVPTNKFKQ
CCHHHHHHHHHHHHHCCCEECCCCEEEECCEEEEEECCCCCCCCCCEEEECCCCCHHHHH
AGDKSDPVSFDIKLTDCDTSIAQNAYFTFTGTSSAGQPKLLATIGSATNVGIRLQAASGE
CCCCCCCEEEEEEEECCCCHHHCCEEEEEECCCCCCCCEEEEEECCCCCCEEEEEECCCC
YLDNGAEQKAPTLLQNGTNTARFAAMYEATAAGVTPGTADGVANFTVRYQ
HHCCCCCCCCCHHHHCCCCCHHHEEEHHHHHCCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8636962; 11251843; 12657207 [H]