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The map label for this gene is gltC [H]

Identifier: 116689613

GI number: 116689613

Start: 1752199

End: 1753173

Strand: Direct

Name: gltC [H]

Synonym: Bcen2424_1591

Alternate gene names: 116689613

Gene position: 1752199-1753173 (Clockwise)

Preceding gene: 116689610

Following gene: 116689614

Centisome position: 50.29

GC content: 71.38

Gene sequence:

>975_bases
ATGCGGCGCGGAGACACGACGATGGCGGCTTTCCTGCATGGCCTGGCACTGCGGTACTTCGTCGAGGTGGCGCGTACCGG
CTCGATCAGCGACGCGTCGGCGCGGCTGCACGTGGCCGTGTCGGCGATCAGCCGCCAGATCGCGAAGCTGGAGAGCGAGC
TCGGCGCGCCGCTGTTCGAGCGGCGGCCGCGCGGGATGGCGTTGTCGGAGGCCGGCGAGCGATTGCTGGCGTTCGCGCAG
CGCAGCCTGCTGGAGGCCGAGCACGTGATGAAGGACATCGGCGGGCTCGACGCGCTGCACGGCAGCCTGCTGAAGATCGC
GTGCTCGGAAGGGTTCGCGATCGATTTCCTGCCCGGCGTGCTCGCGAGCTTCAAGGCGCGCCACCCGGGGGTCGATTTCA
TCGTGTGGGTCGTGTCGCCGGCGGACGCGACCCGGCGCGTGCGCGACGGCGATGCGGACATCGCGTTGACCTTCAGCCTC
GCGCCGGAGAAGGGCGTGCGTGTCGACCACACGGAGCGCGCGCCGGTCTTTGCGCTGGTCCGGCACGATCACCCGCTCGC
GGCGCGCGATGCGGTGTCGCTCGCCGATGTCGCGCGGCACGCGCATGTGCTGCCCGAGGCCGGCACGACGGTGCGCCAGC
TGATCGACATCGCGTGCGCGCTCGACGGGCTGCTGCTCGAGCCCGAGCTGACGAGCAACAACACCGCGGCGATGTACGGC
TACGCGCGGCGCACGGGCGCGGTGATGTTCACGGGGCTGCTGTCGGTGCGCGACCGTGCCGATGCGGACGGCTTCGTCGT
CGTGCCCTTGACGAACCCGCAACTGCGCGAACGCAGCATCCAGGTGCAGACGATGGCGGGGCGCGATCTGCCCGCGTCGG
TACGCGCATTTCGCGACCATCTGATCGACGCGATGCAGGCCGCCTCGCCGCCGCCGACCGCCGCGCGAGGCCCGGGACGC
CGGCCCGTGAGATAA

Upstream 100 bases:

>100_bases
GGCAACGTGAAGTGCGATCGATTCTAGAAAGCCGGTTTTTTTGTCACAATGATCGAATTTCGAACCTTTCTTTGCCGAAA
AGGCAAAGCAGCGCGGCCGG

Downstream 100 bases:

>100_bases
TCGTCAATCCGCCTTCCGTGCCCATGCGGCTCCTCGAGCCGCATCGCCCCTGTTCGACGCCAAATTGAAGAACCTGATTG
TCACCCTCGATCGCGCCGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MRRGDTTMAAFLHGLALRYFVEVARTGSISDASARLHVAVSAISRQIAKLESELGAPLFERRPRGMALSEAGERLLAFAQ
RSLLEAEHVMKDIGGLDALHGSLLKIACSEGFAIDFLPGVLASFKARHPGVDFIVWVVSPADATRRVRDGDADIALTFSL
APEKGVRVDHTERAPVFALVRHDHPLAARDAVSLADVARHAHVLPEAGTTVRQLIDIACALDGLLLEPELTSNNTAAMYG
YARRTGAVMFTGLLSVRDRADADGFVVVPLTNPQLRERSIQVQTMAGRDLPASVRAFRDHLIDAMQAASPPPTAARGPGR
RPVR

Sequences:

>Translated_324_residues
MRRGDTTMAAFLHGLALRYFVEVARTGSISDASARLHVAVSAISRQIAKLESELGAPLFERRPRGMALSEAGERLLAFAQ
RSLLEAEHVMKDIGGLDALHGSLLKIACSEGFAIDFLPGVLASFKARHPGVDFIVWVVSPADATRRVRDGDADIALTFSL
APEKGVRVDHTERAPVFALVRHDHPLAARDAVSLADVARHAHVLPEAGTTVRQLIDIACALDGLLLEPELTSNNTAAMYG
YARRTGAVMFTGLLSVRDRADADGFVVVPLTNPQLRERSIQVQTMAGRDLPASVRAFRDHLIDAMQAASPPPTAARGPGR
RPVR
>Mature_324_residues
MRRGDTTMAAFLHGLALRYFVEVARTGSISDASARLHVAVSAISRQIAKLESELGAPLFERRPRGMALSEAGERLLAFAQ
RSLLEAEHVMKDIGGLDALHGSLLKIACSEGFAIDFLPGVLASFKARHPGVDFIVWVVSPADATRRVRDGDADIALTFSL
APEKGVRVDHTERAPVFALVRHDHPLAARDAVSLADVARHAHVLPEAGTTVRQLIDIACALDGLLLEPELTSNNTAAMYG
YARRTGAVMFTGLLSVRDRADADGFVVVPLTNPQLRERSIQVQTMAGRDLPASVRAFRDHLIDAMQAASPPPTAARGPGR
RPVR

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=272, Percent_Identity=29.7794117647059, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI145693105, Length=201, Percent_Identity=23.3830845771144, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788748, Length=214, Percent_Identity=27.1028037383178, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790208, Length=140, Percent_Identity=37.1428571428571, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788296, Length=235, Percent_Identity=29.7872340425532, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787601, Length=205, Percent_Identity=28.780487804878, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787530, Length=256, Percent_Identity=28.125, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787879, Length=293, Percent_Identity=25.938566552901, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788887, Length=188, Percent_Identity=30.8510638297872, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788297, Length=217, Percent_Identity=26.7281105990783, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789204, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790262, Length=182, Percent_Identity=26.3736263736264, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789639, Length=112, Percent_Identity=32.1428571428571, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081904, Length=202, Percent_Identity=26.7326732673267, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789173, Length=159, Percent_Identity=33.9622641509434, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34925; Mature: 34925

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRGDTTMAAFLHGLALRYFVEVARTGSISDASARLHVAVSAISRQIAKLESELGAPLFE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RRPRGMALSEAGERLLAFAQRSLLEAEHVMKDIGGLDALHGSLLKIACSEGFAIDFLPGV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEHHCCCCEEHHHHHH
LASFKARHPGVDFIVWVVSPADATRRVRDGDADIALTFSLAPEKGVRVDHTERAPVFALV
HHHHHCCCCCCEEEEEEECCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEE
RHDHPLAARDAVSLADVARHAHVLPEAGTTVRQLIDIACALDGLLLEPELTSNNTAAMYG
ECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEECCCCCCCCCEEEEH
YARRTGAVMFTGLLSVRDRADADGFVVVPLTNPQLRERSIQVQTMAGRDLPASVRAFRDH
HHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHCEEEEEECCCCCCHHHHHHHHH
LIDAMQAASPPPTAARGPGRRPVR
HHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRGDTTMAAFLHGLALRYFVEVARTGSISDASARLHVAVSAISRQIAKLESELGAPLFE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RRPRGMALSEAGERLLAFAQRSLLEAEHVMKDIGGLDALHGSLLKIACSEGFAIDFLPGV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEHHCCCCEEHHHHHH
LASFKARHPGVDFIVWVVSPADATRRVRDGDADIALTFSLAPEKGVRVDHTERAPVFALV
HHHHHCCCCCCEEEEEEECCCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEE
RHDHPLAARDAVSLADVARHAHVLPEAGTTVRQLIDIACALDGLLLEPELTSNNTAAMYG
ECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEECCCCCCCCCEEEEH
YARRTGAVMFTGLLSVRDRADADGFVVVPLTNPQLRERSIQVQTMAGRDLPASVRAFRDH
HHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHCEEEEEECCCCCCHHHHHHHHH
LIDAMQAASPPPTAARGPGRRPVR
HHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]