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The map label for this gene is tas [H]

Identifier: 116689610

GI number: 116689610

Start: 1748162

End: 1749214

Strand: Direct

Name: tas [H]

Synonym: Bcen2424_1588

Alternate gene names: 116689610

Gene position: 1748162-1749214 (Clockwise)

Preceding gene: 116689609

Following gene: 116689613

Centisome position: 50.18

GC content: 66.76

Gene sequence:

>1053_bases
ATGGAATACCGCACACTCGGCGATTCGGGCATCGAGGTCAGCCTGATCGGTCTCGGCACGATGACGTGGGGCGAGCAGAA
TTCGGAGCGCGACGCGCACGAGCAGATCGACTACGCGCTCGGGCACGGCGTGACGCTGATCGATGCCGCGGAGATGTATC
CGGTGCCGCCGAAGCCCGACACGCAGGGCCGCACCGAGCAGTACATCGGCACCTGGATCGCGCAGCATCGCGCGCAGCGC
GACCGCATCGTGCTCGCGACGAAGATCGCGGGGCCGGCGCGGCAGCCGCACAATCCGCGTCATATTCGCGGCGAGGGCAA
CCAGTTCGACCGCAAGAACCTGACCGAAGCGCTCGACGGCAGCCTCAAGCGCCTGCAGACCGACTACGTCGATCTCTACC
AACTGCATTGGCCCGATCGCAGCACGACCACCTTCGGCCGTCCTGCGTATCCGTGGGTCGACGACGCGTACACGGTGCCG
ATCGAAGAAACGCTCGGTGTGCTCGCGGAATTCGTGAAGGCCGGCAAGGTGCGCGCGATCGGCGTGTCGAACGAAACGCC
ATGGGGTGTCGCGCAGTTCCTGCGCGCGGCCGAGCGGCTCAGGCTGCCGCGTATCGCGAGCATCCAGAATCCGTACAGTC
TGCTGAACCGCACGTTCGAGAACGGGCTGTCGGAGTTCACGCATCGCGACGGCGTCGGCCTGCTCGCGTATTCGCCGCTC
GCATTCGGCTGGCTGTCGGGCAAGTACGAGAACGGCGCGCGTCCGGCCGGCGCGCGGATCACGCTGTTCGAGCGCTTCCA
GCGTTACAGCAAGCCGCAGGCCGTCGAGGCGACGTCGCGTTACGTCGCGCTCGCGCAGCGTCACGGGCTGTCGCCCGCGC
AACTGGCGCTCGCGTTCGTCAACAGCCGCCCGTTCGTGCGCAGCAACCTGGTCGGCGCGACGTCGCTCGAGCAGTTGAAG
GAAAACATCGGCAGCGTCGACGTGACGCTGTCCGACGAGATCCTCGCCGAGATCGATGCATTGCACGAACGGCAGCCGAA
CCCGGCGCCGTAA

Upstream 100 bases:

>100_bases
GCAGCGCCGAAGGCCGCTTGTAAGCGTGCGCGGGGCCCATCTGAAGCAGTGGCTTCAATGTGATAGCGTTCCTGCTTTCC
ACTGACGCGACAGGAACAGC

Downstream 100 bases:

>100_bases
ACGGCGCGCGGCCCGCGCGGCAGCGATGCCGCGACGGGCCGAGTCGCACCGAGTCCGGCGGTTTCGGCGGCGCCTTGCTG
CGCCGCCGTTTCTCGCGTCA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MEYRTLGDSGIEVSLIGLGTMTWGEQNSERDAHEQIDYALGHGVTLIDAAEMYPVPPKPDTQGRTEQYIGTWIAQHRAQR
DRIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALDGSLKRLQTDYVDLYQLHWPDRSTTTFGRPAYPWVDDAYTVP
IEETLGVLAEFVKAGKVRAIGVSNETPWGVAQFLRAAERLRLPRIASIQNPYSLLNRTFENGLSEFTHRDGVGLLAYSPL
AFGWLSGKYENGARPAGARITLFERFQRYSKPQAVEATSRYVALAQRHGLSPAQLALAFVNSRPFVRSNLVGATSLEQLK
ENIGSVDVTLSDEILAEIDALHERQPNPAP

Sequences:

>Translated_350_residues
MEYRTLGDSGIEVSLIGLGTMTWGEQNSERDAHEQIDYALGHGVTLIDAAEMYPVPPKPDTQGRTEQYIGTWIAQHRAQR
DRIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALDGSLKRLQTDYVDLYQLHWPDRSTTTFGRPAYPWVDDAYTVP
IEETLGVLAEFVKAGKVRAIGVSNETPWGVAQFLRAAERLRLPRIASIQNPYSLLNRTFENGLSEFTHRDGVGLLAYSPL
AFGWLSGKYENGARPAGARITLFERFQRYSKPQAVEATSRYVALAQRHGLSPAQLALAFVNSRPFVRSNLVGATSLEQLK
ENIGSVDVTLSDEILAEIDALHERQPNPAP
>Mature_350_residues
MEYRTLGDSGIEVSLIGLGTMTWGEQNSERDAHEQIDYALGHGVTLIDAAEMYPVPPKPDTQGRTEQYIGTWIAQHRAQR
DRIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALDGSLKRLQTDYVDLYQLHWPDRSTTTFGRPAYPWVDDAYTVP
IEETLGVLAEFVKAGKVRAIGVSNETPWGVAQFLRAAERLRLPRIASIQNPYSLLNRTFENGLSEFTHRDGVGLLAYSPL
AFGWLSGKYENGARPAGARITLFERFQRYSKPQAVEATSRYVALAQRHGLSPAQLALAFVNSRPFVRSNLVGATSLEQLK
ENIGSVDVTLSDEILAEIDALHERQPNPAP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=358, Percent_Identity=31.0055865921788, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI27436964, Length=360, Percent_Identity=30.8333333333333, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI4504825, Length=356, Percent_Identity=30.8988764044944, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI27436962, Length=360, Percent_Identity=30.8333333333333, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI27436966, Length=360, Percent_Identity=30.5555555555556, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI27436971, Length=363, Percent_Identity=30.5785123966942, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI41152114, Length=240, Percent_Identity=30.4166666666667, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI41327764, Length=330, Percent_Identity=26.969696969697, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI223718702, Length=306, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1789199, Length=350, Percent_Identity=57.1428571428571, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI87081735, Length=356, Percent_Identity=29.2134831460674, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789375, Length=348, Percent_Identity=32.183908045977, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1788070, Length=343, Percent_Identity=30.6122448979592, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1788081, Length=356, Percent_Identity=26.9662921348315, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325169, Length=355, Percent_Identity=25.3521126760563, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323998, Length=347, Percent_Identity=26.8011527377522, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6319958, Length=325, Percent_Identity=27.0769230769231, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=338, Percent_Identity=26.3313609467456, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324694, Length=248, Percent_Identity=31.0483870967742, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322615, Length=270, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6320576, Length=311, Percent_Identity=26.6881028938907, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6320079, Length=235, Percent_Identity=29.7872340425532, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646159, Length=334, Percent_Identity=27.2455089820359, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24646155, Length=343, Percent_Identity=27.6967930029155, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38999; Mature: 38999

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRTLGDSGIEVSLIGLGTMTWGEQNSERDAHEQIDYALGHGVTLIDAAEMYPVPPKPD
CCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHCCCCCCCC
TQGRTEQYIGTWIAQHRAQRDRIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALDG
CCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEECCCCCCCCHHHHHHHHHH
SLKRLQTDYVDLYQLHWPDRSTTTFGRPAYPWVDDAYTVPIEETLGVLAEFVKAGKVRAI
HHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCEEEE
GVSNETPWGVAQFLRAAERLRLPRIASIQNPYSLLNRTFENGLSEFTHRDGVGLLAYSPL
ECCCCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCH
AFGWLSGKYENGARPAGARITLFERFQRYSKPQAVEATSRYVALAQRHGLSPAQLALAFV
HHHHHCCCCCCCCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
NSRPFVRSNLVGATSLEQLKENIGSVDVTLSDEILAEIDALHERQPNPAP
CCCCCHHHCCCCHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEYRTLGDSGIEVSLIGLGTMTWGEQNSERDAHEQIDYALGHGVTLIDAAEMYPVPPKPD
CCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHCCCCCCCC
TQGRTEQYIGTWIAQHRAQRDRIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALDG
CCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEECCCCCCCCHHHHHHHHHH
SLKRLQTDYVDLYQLHWPDRSTTTFGRPAYPWVDDAYTVPIEETLGVLAEFVKAGKVRAI
HHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCEEEE
GVSNETPWGVAQFLRAAERLRLPRIASIQNPYSLLNRTFENGLSEFTHRDGVGLLAYSPL
ECCCCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCH
AFGWLSGKYENGARPAGARITLFERFQRYSKPQAVEATSRYVALAQRHGLSPAQLALAFV
HHHHHCCCCCCCCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
NSRPFVRSNLVGATSLEQLKENIGSVDVTLSDEILAEIDALHERQPNPAP
CCCCCHHHCCCCHHHHHHHHHHHCCEEEEECHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]