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The map label for this gene is yafC [C]

Identifier: 116689472

GI number: 116689472

Start: 1605265

End: 1606206

Strand: Direct

Name: yafC [C]

Synonym: Bcen2424_1450

Alternate gene names: 116689472

Gene position: 1605265-1606206 (Clockwise)

Preceding gene: 116689467

Following gene: 116689478

Centisome position: 46.08

GC content: 68.37

Gene sequence:

>942_bases
ATGGATACGCTACAAAACATGCGGGTATTCGTCCGCGTGGTGGACGCGGGAAGCTTTACCGCGGCCGCCCAGCAGATGAA
TTCGACCACCGCCTACGCGTCGCGCGCGGTCTCGGATCTCGAGGCCCACCTGCGCACGCGTCTCCTGAACCGCACGACGC
GCCGGATCGCGCTGACCGAAGCGGGCGAGCGCTATCTGCAGCGCTGCGAACAGATCCTCGCTTACGTCGACCAGGCCGAA
GCCGAGGCGGGCGACGCGCACGCGCGTCCGTCCGGCAAGCTGAAGGTCCATTGCTTCACGAGCCTCGGCCAGCACTATCT
GGTGCCGGCCATCGCGCGCTATCGCGAGCGCTATCCGGACGTGCACGTCGAGCTGACGCTCGCGCAGCGGATGCCCGACC
TGCTCGACGAGGGCTACGACGTCGCGATCGTCGTCGGCCGCGATCTGCCCGATTCGGGGCTCGTGTCGCAGCGGCTCGGC
GAGAGCTACAGCGTCGTGTGCGCATCGCCGGGTTATGTCGAGTCGCACGGCGTGCCGCAGCGGCCGGCCGATCTCGCGCA
GCACGTGTGCCTCGGGATGGTCGCGCCGGGCTTTCACTTCGACGAATGGGCGCTGGCGGGGCCGAACGGCGACGAGGTCG
TGCCGATCACGGCGCCGCCGTTCCGCGTGAACGTCGCGGAGGCGCTCGCGGTGGCCGTGCGGGAGGGGATGGGCGTCGGC
GGGCTGCCGCTCTATTCGGCGATCGGCTGGCTGCGCAGCGGGCACATCGTGCGCGTGATGCCCGAGTACCGGTCGCACGT
GATGAACATCTATGCGCTGTATCCGTCGCGCCAGTACCTCGACGCGAAAATCCGGACCTGGGTCGATTTCCTGCGCGAAG
AGCTGCCGCTCACGCTCGAAGCCGACGAAGCGGCGCTCGAACAGTACACGCGTGCGACATGA

Upstream 100 bases:

>100_bases
CTGAATAAACGGACAACGGTGCAAGTCATTTTTACGAATCCTGAGATAATATTTGTTGGACCCTGTGCAACAATCCCTCC
GGATTCAAACGGGTAATGGG

Downstream 100 bases:

>100_bases
CCGCGCGGTCGGCCGCCATCTGACGAGATTTGTCCTTCACGCAACATTTTTTTACGAACGTGTGTCAGACAGTTTGATAC
TGTTGGAATTAACGAGATAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MDTLQNMRVFVRVVDAGSFTAAAQQMNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTEAGERYLQRCEQILAYVDQAE
AEAGDAHARPSGKLKVHCFTSLGQHYLVPAIARYRERYPDVHVELTLAQRMPDLLDEGYDVAIVVGRDLPDSGLVSQRLG
ESYSVVCASPGYVESHGVPQRPADLAQHVCLGMVAPGFHFDEWALAGPNGDEVVPITAPPFRVNVAEALAVAVREGMGVG
GLPLYSAIGWLRSGHIVRVMPEYRSHVMNIYALYPSRQYLDAKIRTWVDFLREELPLTLEADEAALEQYTRAT

Sequences:

>Translated_313_residues
MDTLQNMRVFVRVVDAGSFTAAAQQMNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTEAGERYLQRCEQILAYVDQAE
AEAGDAHARPSGKLKVHCFTSLGQHYLVPAIARYRERYPDVHVELTLAQRMPDLLDEGYDVAIVVGRDLPDSGLVSQRLG
ESYSVVCASPGYVESHGVPQRPADLAQHVCLGMVAPGFHFDEWALAGPNGDEVVPITAPPFRVNVAEALAVAVREGMGVG
GLPLYSAIGWLRSGHIVRVMPEYRSHVMNIYALYPSRQYLDAKIRTWVDFLREELPLTLEADEAALEQYTRAT
>Mature_313_residues
MDTLQNMRVFVRVVDAGSFTAAAQQMNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTEAGERYLQRCEQILAYVDQAE
AEAGDAHARPSGKLKVHCFTSLGQHYLVPAIARYRERYPDVHVELTLAQRMPDLLDEGYDVAIVVGRDLPDSGLVSQRLG
ESYSVVCASPGYVESHGVPQRPADLAQHVCLGMVAPGFHFDEWALAGPNGDEVVPITAPPFRVNVAEALAVAVREGMGVG
GLPLYSAIGWLRSGHIVRVMPEYRSHVMNIYALYPSRQYLDAKIRTWVDFLREELPLTLEADEAALEQYTRAT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=35.6164383561644, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=35.7142857142857, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI87081978, Length=290, Percent_Identity=31.7241379310345, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=29.2682926829268, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=29.7945205479452, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=26.7123287671233, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=24.9146757679181, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789173, Length=189, Percent_Identity=31.2169312169312, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788481, Length=295, Percent_Identity=24.406779661017, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI145693105, Length=122, Percent_Identity=29.5081967213115, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787879, Length=154, Percent_Identity=31.8181818181818, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788748, Length=123, Percent_Identity=32.520325203252, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786448, Length=296, Percent_Identity=22.6351351351351, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788706, Length=184, Percent_Identity=25, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34681; Mature: 34681

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLQNMRVFVRVVDAGSFTAAAQQMNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTE
CCCHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGERYLQRCEQILAYVDQAEAEAGDAHARPSGKLKVHCFTSLGQHYLVPAIARYRERYPD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHCCC
VHVELTLAQRMPDLLDEGYDVAIVVGRDLPDSGLVSQRLGESYSVVCASPGYVESHGVPQ
EEEEEEHHHHCHHHHHCCCCEEEEEECCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCC
RPADLAQHVCLGMVAPGFHFDEWALAGPNGDEVVPITAPPFRVNVAEALAVAVREGMGVG
CHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEECCCCCEECHHHHHHHHHHHCCCCC
GLPLYSAIGWLRSGHIVRVMPEYRSHVMNIYALYPSRQYLDAKIRTWVDFLREELPLTLE
CHHHHHHHHHHHCCCEEEECHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEE
ADEAALEQYTRAT
CCHHHHHHHHCCC
>Mature Secondary Structure
MDTLQNMRVFVRVVDAGSFTAAAQQMNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTE
CCCHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGERYLQRCEQILAYVDQAEAEAGDAHARPSGKLKVHCFTSLGQHYLVPAIARYRERYPD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHCCC
VHVELTLAQRMPDLLDEGYDVAIVVGRDLPDSGLVSQRLGESYSVVCASPGYVESHGVPQ
EEEEEEHHHHCHHHHHCCCCEEEEEECCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCC
RPADLAQHVCLGMVAPGFHFDEWALAGPNGDEVVPITAPPFRVNVAEALAVAVREGMGVG
CHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEECCCCCEECHHHHHHHHHHHCCCCC
GLPLYSAIGWLRSGHIVRVMPEYRSHVMNIYALYPSRQYLDAKIRTWVDFLREELPLTLE
CHHHHHHHHHHHCCCEEEECHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEE
ADEAALEQYTRAT
CCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]