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The map label for this gene is yegE [C]

Identifier: 116689400

GI number: 116689400

Start: 1516506

End: 1517699

Strand: Reverse

Name: yegE [C]

Synonym: Bcen2424_1378

Alternate gene names: 116689400

Gene position: 1517699-1516506 (Counterclockwise)

Preceding gene: 116689411

Following gene: 116689395

Centisome position: 43.56

GC content: 70.52

Gene sequence:

>1194_bases
ATGGCAAGAATTGCGCCGTTGCCGCCGGATGGCTGGAACGGCATACTGCCGGCGCGGTACGGCTGGCCGGGCACCGGCCA
CGTTCCGGTGCGAACCGCCCGGCACGCGCTGCCGCGAGCGGCGCGTATGCTACCGCAAGCGCGCGCCGCGCGATGCACTT
TTTCACGGAAAACTGACTTGAATCAAACCACCGACGCCGCCACGCCGTCCCCCGACACGTTGTTGCGCATCATCGCCGCG
CAAGCCGAAATCGCGAAACTCGGCCTCGACCTCGGCAGCGTGATGGCCTACGTGGCCGAACAGGTGCCCCAGCTCACCGG
CGCGAGCGCCGCCGCGGTCGAATTCGCCGAAGGCGACGACATGGTGTACCGCGCCGCGTCGGGCACGGCCGCCGGGATGC
TCGGCCTGCGGTTGCGGCGCTCGGGCAGCCTGTCGGGCCTGTGCGTGCAGCAGGGCGCGTTGCTGCACTGTATCGATTCG
GAAACCGACCCACGCGTCGATCGCGACGCATGCCGCCGGGTCGGCCTGCGCTCGATGCTCGTGATGCCGCTCACGCACGC
CGACACGACGGTCGGCGTGCTGAAGGTGATGTCGCCGGACGTCGACGGTTTCTCACCGGCCGACGCCGGCACGCTGCGGC
TGATGGCCGACCTGATCGCCGCCGCGATGTTCCACGCGGCGCGCAACGAAGCGAACGAGCTGTACCTGCGCGCGACGCAC
GACGCGCTCACGGGCCTGCCGAACCGCGCGCTGTTCTACGACCGCCTGCGCCAGTCGATGCACACGGCGCTGCGCGCGAG
CGGCCGGCTCGGCATTCTCAACATCGACATGGACGGCCTGAAGCCGATCAACGACGGGTTCGGCCACCGCGCGGGCGACG
CCGCGCTGCGCGAGGTCGCCACGCGGATGCAGGCCGCGGTGCGGCGCTCGGACACGGTCGCGCGCATCGGCGGCGACGAA
TTCGCGGTGATCCTGCCGAACCTCGGCACCCGCGACGACGCCCAGGTGCAAAGCACGCGGCTCGCGCGGCAGGTCGGCGA
GCCGTTCGAATTCGACGGGCATGCGCTGCGGCTCGGCGTCAGCGTCGGCATCGCGATGCTGCCGGACGACGGCACCGACA
TGAACGCGCTGATCGAGCATGCGGACCAGGCGATGTACGAAGCCAAGCGATCGCGGCGCACCGCGCACGCATGA

Upstream 100 bases:

>100_bases
TTGTCACACTATCTCAAAAATAGAACAAAACTCACCGTGATTCGCGACTGAGAAGCGAAAAAATCTCAATTCGGTCGGAA
ATGCCGCGCAGGAAGAGTGA

Downstream 100 bases:

>100_bases
CGGCTGGCGCGCGCCGGCCGGGCTGTTCCCGCCGATAGCCGGCTTGCGCCGGCGCTAGCCGATGGGCGACACCGCGACCG
CGATCCCGACGACGAGCCAC

Product: diguanylate cyclase with GAF sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MARIAPLPPDGWNGILPARYGWPGTGHVPVRTARHALPRAARMLPQARAARCTFSRKTDLNQTTDAATPSPDTLLRIIAA
QAEIAKLGLDLGSVMAYVAEQVPQLTGASAAAVEFAEGDDMVYRAASGTAAGMLGLRLRRSGSLSGLCVQQGALLHCIDS
ETDPRVDRDACRRVGLRSMLVMPLTHADTTVGVLKVMSPDVDGFSPADAGTLRLMADLIAAAMFHAARNEANELYLRATH
DALTGLPNRALFYDRLRQSMHTALRASGRLGILNIDMDGLKPINDGFGHRAGDAALREVATRMQAAVRRSDTVARIGGDE
FAVILPNLGTRDDAQVQSTRLARQVGEPFEFDGHALRLGVSVGIAMLPDDGTDMNALIEHADQAMYEAKRSRRTAHA

Sequences:

>Translated_397_residues
MARIAPLPPDGWNGILPARYGWPGTGHVPVRTARHALPRAARMLPQARAARCTFSRKTDLNQTTDAATPSPDTLLRIIAA
QAEIAKLGLDLGSVMAYVAEQVPQLTGASAAAVEFAEGDDMVYRAASGTAAGMLGLRLRRSGSLSGLCVQQGALLHCIDS
ETDPRVDRDACRRVGLRSMLVMPLTHADTTVGVLKVMSPDVDGFSPADAGTLRLMADLIAAAMFHAARNEANELYLRATH
DALTGLPNRALFYDRLRQSMHTALRASGRLGILNIDMDGLKPINDGFGHRAGDAALREVATRMQAAVRRSDTVARIGGDE
FAVILPNLGTRDDAQVQSTRLARQVGEPFEFDGHALRLGVSVGIAMLPDDGTDMNALIEHADQAMYEAKRSRRTAHA
>Mature_396_residues
ARIAPLPPDGWNGILPARYGWPGTGHVPVRTARHALPRAARMLPQARAARCTFSRKTDLNQTTDAATPSPDTLLRIIAAQ
AEIAKLGLDLGSVMAYVAEQVPQLTGASAAAVEFAEGDDMVYRAASGTAAGMLGLRLRRSGSLSGLCVQQGALLHCIDSE
TDPRVDRDACRRVGLRSMLVMPLTHADTTVGVLKVMSPDVDGFSPADAGTLRLMADLIAAAMFHAARNEANELYLRATHD
ALTGLPNRALFYDRLRQSMHTALRASGRLGILNIDMDGLKPINDGFGHRAGDAALREVATRMQAAVRRSDTVARIGGDEF
AVILPNLGTRDDAQVQSTRLARQVGEPFEFDGHALRLGVSVGIAMLPDDGTDMNALIEHADQAMYEAKRSRRTAHA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=174, Percent_Identity=37.9310344827586, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787541, Length=166, Percent_Identity=33.7349397590361, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87081977, Length=231, Percent_Identity=30.7359307359307, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788956, Length=181, Percent_Identity=33.1491712707182, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1787802, Length=176, Percent_Identity=31.25, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082007, Length=227, Percent_Identity=27.7533039647577, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693134, Length=162, Percent_Identity=35.8024691358025, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081974, Length=154, Percent_Identity=30.5194805194805, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786584, Length=162, Percent_Identity=31.4814814814815, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787262, Length=159, Percent_Identity=29.559748427673, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87081881, Length=189, Percent_Identity=30.1587301587302, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1787816, Length=171, Percent_Identity=32.1637426900585, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 42555; Mature: 42424

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIAPLPPDGWNGILPARYGWPGTGHVPVRTARHALPRAARMLPQARAARCTFSRKTDL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NQTTDAATPSPDTLLRIIAAQAEIAKLGLDLGSVMAYVAEQVPQLTGASAAAVEFAEGDD
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHEEEECCCCC
MVYRAASGTAAGMLGLRLRRSGSLSGLCVQQGALLHCIDSETDPRVDRDACRRVGLRSML
EEEEECCCCHHHHHHHHHHCCCCCCCEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
VMPLTHADTTVGVLKVMSPDVDGFSPADAGTLRLMADLIAAAMFHAARNEANELYLRATH
HHCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECH
DALTGLPNRALFYDRLRQSMHTALRASGRLGILNIDMDGLKPINDGFGHRAGDAALREVA
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
TRMQAAVRRSDTVARIGGDEFAVILPNLGTRDDAQVQSTRLARQVGEPFEFDGHALRLGV
HHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEE
SVGIAMLPDDGTDMNALIEHADQAMYEAKRSRRTAHA
EECEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARIAPLPPDGWNGILPARYGWPGTGHVPVRTARHALPRAARMLPQARAARCTFSRKTDL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NQTTDAATPSPDTLLRIIAAQAEIAKLGLDLGSVMAYVAEQVPQLTGASAAAVEFAEGDD
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHEEEECCCCC
MVYRAASGTAAGMLGLRLRRSGSLSGLCVQQGALLHCIDSETDPRVDRDACRRVGLRSML
EEEEECCCCHHHHHHHHHHCCCCCCCEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
VMPLTHADTTVGVLKVMSPDVDGFSPADAGTLRLMADLIAAAMFHAARNEANELYLRATH
HHCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECH
DALTGLPNRALFYDRLRQSMHTALRASGRLGILNIDMDGLKPINDGFGHRAGDAALREVA
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
TRMQAAVRRSDTVARIGGDEFAVILPNLGTRDDAQVQSTRLARQVGEPFEFDGHALRLGV
HHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEE
SVGIAMLPDDGTDMNALIEHADQAMYEAKRSRRTAHA
EECEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]