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The map label for this gene is yybE [H]

Identifier: 116689388

GI number: 116689388

Start: 1504128

End: 1505024

Strand: Reverse

Name: yybE [H]

Synonym: Bcen2424_1366

Alternate gene names: 116689388

Gene position: 1505024-1504128 (Counterclockwise)

Preceding gene: 116689394

Following gene: 116689385

Centisome position: 43.2

GC content: 71.35

Gene sequence:

>897_bases
ATGGATCTGAATCTTCGCGACATTCGCGCGTTCGTCACCGTCGCGCACGCCGGCAACTTCACGCGTGCGGCCGCGCGGCT
GCATCTGTCGCAGCCGGCGCTGACCGTGCAGATTCGCCGGCTCGAGGACATCGTCGGCGCGCGCCTGTTCGACCGCAACA
GCCGCAGCGTCGCGCTCACGCAGACCGGCCGCGAGTTGCTGCCGCTGTTGCAGCGCTCGCTCGACGACATGGAACGCGTG
CTGCGCGATGCGCGCGCGCTCGGCGAAGGCGCGAGCGGCACGGTGCGGCTCGCGTGCCTGCCGACCTTCGCGTCGAGCGT
GCTGCCGGAGCTGATCCAGTCGTTCCGGCGCGACGTGCCGCGCGCGGGCTTCGAGATCCGCGACGGCGTCGCGAGCCTCG
TCACCACGCTCGTGCGCAACGAGGATGCCGATCTCGGGCTGACCGGCGGCGATACGTTCGATGCGTCGCTGGAAGTGCTG
TATGCGGGCGCCGACCAGCTCGTCGCCGTGTGCCCGAAGGATCATCCGCTCGCGCGCAAGCGCCGTGTCGGCACCGCCGA
CGTCGCCGGCGTGCCGCTCGTGCTCACCGCGCAAGGCACGAGTGTGCGCAGCGTCGTCGATGCCGCGCTGGAAGCGGCCG
GCTGCACGCCCGACATCGCGTGCGAACCGACCTACATGATGACGGCGGTCGCGATGGTGCGCGGCGGCCTCGGCGTGACG
ATCCTGCCCGCGACCGCGCGCGAGGTGCGCGCCGAGCCCGATCTCGTCGTGAAGCCGATCGACGATCCCGCGTTCGTGCG
GCCGATCGCGCTCGTCGCGAAGCGCGGGCGCACGCTGCCGCGCGTCGCGCAGGCGTTCGCCGACCTCATGCTGGCGGAAT
TGAAAAAGCGCGCATGA

Upstream 100 bases:

>100_bases
CATCCGTGTCTCCTACCTTGTCTTTTGTTGGAGACGAGCGTAAGGTCAGCGCAGCGATAGCACAATTGAAATGATTTGAT
CGCAGCAATCATGAATCGTT

Downstream 100 bases:

>100_bases
CGCGCGCTCTGGTGAGGAATGGCCGACCGTCCGACGCTTACTGCGCGTCCGGATCGACGTCGACATGGAGCGATTCGCCG
ATCGCATAGAAATTGCCGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MDLNLRDIRAFVTVAHAGNFTRAAARLHLSQPALTVQIRRLEDIVGARLFDRNSRSVALTQTGRELLPLLQRSLDDMERV
LRDARALGEGASGTVRLACLPTFASSVLPELIQSFRRDVPRAGFEIRDGVASLVTTLVRNEDADLGLTGGDTFDASLEVL
YAGADQLVAVCPKDHPLARKRRVGTADVAGVPLVLTAQGTSVRSVVDAALEAAGCTPDIACEPTYMMTAVAMVRGGLGVT
ILPATAREVRAEPDLVVKPIDDPAFVRPIALVAKRGRTLPRVAQAFADLMLAELKKRA

Sequences:

>Translated_298_residues
MDLNLRDIRAFVTVAHAGNFTRAAARLHLSQPALTVQIRRLEDIVGARLFDRNSRSVALTQTGRELLPLLQRSLDDMERV
LRDARALGEGASGTVRLACLPTFASSVLPELIQSFRRDVPRAGFEIRDGVASLVTTLVRNEDADLGLTGGDTFDASLEVL
YAGADQLVAVCPKDHPLARKRRVGTADVAGVPLVLTAQGTSVRSVVDAALEAAGCTPDIACEPTYMMTAVAMVRGGLGVT
ILPATAREVRAEPDLVVKPIDDPAFVRPIALVAKRGRTLPRVAQAFADLMLAELKKRA
>Mature_298_residues
MDLNLRDIRAFVTVAHAGNFTRAAARLHLSQPALTVQIRRLEDIVGARLFDRNSRSVALTQTGRELLPLLQRSLDDMERV
LRDARALGEGASGTVRLACLPTFASSVLPELIQSFRRDVPRAGFEIRDGVASLVTTLVRNEDADLGLTGGDTFDASLEVL
YAGADQLVAVCPKDHPLARKRRVGTADVAGVPLVLTAQGTSVRSVVDAALEAAGCTPDIACEPTYMMTAVAMVRGGLGVT
ILPATAREVRAEPDLVVKPIDDPAFVRPIALVAKRGRTLPRVAQAFADLMLAELKKRA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788748, Length=292, Percent_Identity=33.2191780821918, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI145693105, Length=292, Percent_Identity=26.7123287671233, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1787879, Length=303, Percent_Identity=32.013201320132, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1788887, Length=284, Percent_Identity=30.9859154929577, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI157672245, Length=239, Percent_Identity=29.7071129707113, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789204, Length=295, Percent_Identity=30.5084745762712, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1790399, Length=286, Percent_Identity=31.4685314685315, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787530, Length=265, Percent_Identity=28.3018867924528, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788296, Length=226, Percent_Identity=30.9734513274336, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87081904, Length=225, Percent_Identity=30.6666666666667, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI2367136, Length=260, Percent_Identity=25.3846153846154, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788481, Length=246, Percent_Identity=27.6422764227642, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790208, Length=253, Percent_Identity=28.4584980237154, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1788297, Length=245, Percent_Identity=26.1224489795918, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787589, Length=204, Percent_Identity=31.3725490196078, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790262, Length=255, Percent_Identity=25.0980392156863, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787601, Length=178, Percent_Identity=26.4044943820225, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786448, Length=169, Percent_Identity=30.1775147928994, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI87082132, Length=148, Percent_Identity=30.4054054054054, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787806, Length=293, Percent_Identity=23.2081911262799, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786508, Length=177, Percent_Identity=25.9887005649718, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789639, Length=126, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789173, Length=172, Percent_Identity=29.6511627906977, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31949; Mature: 31949

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNLRDIRAFVTVAHAGNFTRAAARLHLSQPALTVQIRRLEDIVGARLFDRNSRSVALT
CCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
QTGRELLPLLQRSLDDMERVLRDARALGEGASGTVRLACLPTFASSVLPELIQSFRRDVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCC
RAGFEIRDGVASLVTTLVRNEDADLGLTGGDTFDASLEVLYAGADQLVAVCPKDHPLARK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCHHHH
RRVGTADVAGVPLVLTAQGTSVRSVVDAALEAAGCTPDIACEPTYMMTAVAMVRGGLGVT
HCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEE
ILPATAREVRAEPDLVVKPIDDPAFVRPIALVAKRGRTLPRVAQAFADLMLAELKKRA
EECCCHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLNLRDIRAFVTVAHAGNFTRAAARLHLSQPALTVQIRRLEDIVGARLFDRNSRSVALT
CCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
QTGRELLPLLQRSLDDMERVLRDARALGEGASGTVRLACLPTFASSVLPELIQSFRRDVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCC
RAGFEIRDGVASLVTTLVRNEDADLGLTGGDTFDASLEVLYAGADQLVAVCPKDHPLARK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCHHHH
RRVGTADVAGVPLVLTAQGTSVRSVVDAALEAAGCTPDIACEPTYMMTAVAMVRGGLGVT
HCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEE
ILPATAREVRAEPDLVVKPIDDPAFVRPIALVAKRGRTLPRVAQAFADLMLAELKKRA
EECCCHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]