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The map label for this gene is ntcA [H]

Identifier: 116622290

GI number: 116622290

Start: 4033481

End: 4034155

Strand: Reverse

Name: ntcA [H]

Synonym: Acid_3184

Alternate gene names: 116622290

Gene position: 4034155-4033481 (Counterclockwise)

Preceding gene: 116622292

Following gene: 116622282

Centisome position: 40.48

GC content: 57.63

Gene sequence:

>675_bases
ATGGCAACCACACCGGTGAGAGTAGAACCCCAAAAAGCTCTTGAAGATCCGTTGGCATACTTGCCGTGCTCCAACGTTCT
GGAATACGGGAAAGGCGAAGTCATCTACAGTCACGACCAGCCGCACAGTGACCTTTACCTGGTGCTGAGCGGAATGGTCA
AAGTGACGAGGGTGTCGAATCAAGGCAGCCAACTTCTGGTTGACCTTTACGGAACCGATGAGTTCTTCGGCGAAGCCGCC
TTCGTCGATCCCCTCCAGGCGTTTGAGCGCGCCACAGCGCACCAGCACACCACTTTGATGGCTTGGAAGGCCAGCGATGT
CGAAGACTTGATTCAGAAGCGTCCCAAGCTCGCGATTGCCCTTCTCCAAGCCTTTGGCCAGCGCTCCCTAAACTTGTTAC
AGCGGCTCGAAAGCCTCTCGGCTGACCGCATTGACAAGCGGCTGGCAATTTCCCTCATCCGTTTTGCCGAACGGCTGGGA
CGTCCGCAGGAAGACGGCAGCATCCACATGGACCCGCTAACCCACGAAGTGCTGGCGCAATATGTGGGGACCTCGCGCGA
ACTGATCACCTGCCACATGGCGAAGTTCCGCAAGGATGGATATCTGCAGTATTCGCGGCGCTCCATCGTCCTCTATCGCG
ATGCGCTCCGGGCCTGGGTCCGGGATAACGCGTGA

Upstream 100 bases:

>100_bases
GTACCAGTTTTGGCAGAGAACGTGCTACCACACACCGCGTTCAGAGGTAAACTATGCAACAGTTTCCTTTGATCAAAAAT
ATTCCCTAAAGGACGTAACA

Downstream 100 bases:

>100_bases
AAAAATGATGACCTCGATTGCGGTTCCTCCCTCCCTCGGCTAGTACCTGCTCAAGCTCACGGGAGGAACCGATGAATCGG
GAAATTCCCCTGCTCGTTCC

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MATTPVRVEPQKALEDPLAYLPCSNVLEYGKGEVIYSHDQPHSDLYLVLSGMVKVTRVSNQGSQLLVDLYGTDEFFGEAA
FVDPLQAFERATAHQHTTLMAWKASDVEDLIQKRPKLAIALLQAFGQRSLNLLQRLESLSADRIDKRLAISLIRFAERLG
RPQEDGSIHMDPLTHEVLAQYVGTSRELITCHMAKFRKDGYLQYSRRSIVLYRDALRAWVRDNA

Sequences:

>Translated_224_residues
MATTPVRVEPQKALEDPLAYLPCSNVLEYGKGEVIYSHDQPHSDLYLVLSGMVKVTRVSNQGSQLLVDLYGTDEFFGEAA
FVDPLQAFERATAHQHTTLMAWKASDVEDLIQKRPKLAIALLQAFGQRSLNLLQRLESLSADRIDKRLAISLIRFAERLG
RPQEDGSIHMDPLTHEVLAQYVGTSRELITCHMAKFRKDGYLQYSRRSIVLYRDALRAWVRDNA
>Mature_223_residues
ATTPVRVEPQKALEDPLAYLPCSNVLEYGKGEVIYSHDQPHSDLYLVLSGMVKVTRVSNQGSQLLVDLYGTDEFFGEAAF
VDPLQAFERATAHQHTTLMAWKASDVEDLIQKRPKLAIALLQAFGQRSLNLLQRLESLSADRIDKRLAISLIRFAERLGR
PQEDGSIHMDPLTHEVLAQYVGTSRELITCHMAKFRKDGYLQYSRRSIVLYRDALRAWVRDNA

Specific function: Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR022299
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25415; Mature: 25284

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTPVRVEPQKALEDPLAYLPCSNVLEYGKGEVIYSHDQPHSDLYLVLSGMVKVTRVSN
CCCCCCCCCHHHHHHCCHHHCCHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHEEECC
QGSQLLVDLYGTDEFFGEAAFVDPLQAFERATAHQHTTLMAWKASDVEDLIQKRPKLAIA
CCCEEEEEEECCHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCHHHHHH
LLQAFGQRSLNLLQRLESLSADRIDKRLAISLIRFAERLGRPQEDGSIHMDPLTHEVLAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHH
YVGTSRELITCHMAKFRKDGYLQYSRRSIVLYRDALRAWVRDNA
HHCCCHHHHHHHHHHHCCCCCEEECCCCCEEHHHHHHHHHHCCC
>Mature Secondary Structure 
ATTPVRVEPQKALEDPLAYLPCSNVLEYGKGEVIYSHDQPHSDLYLVLSGMVKVTRVSN
CCCCCCCCHHHHHHCCHHHCCHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHEEECC
QGSQLLVDLYGTDEFFGEAAFVDPLQAFERATAHQHTTLMAWKASDVEDLIQKRPKLAIA
CCCEEEEEEECCHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCHHHHHH
LLQAFGQRSLNLLQRLESLSADRIDKRLAISLIRFAERLGRPQEDGSIHMDPLTHEVLAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHH
YVGTSRELITCHMAKFRKDGYLQYSRRSIVLYRDALRAWVRDNA
HHCCCHHHHHHHHHHHCCCCCEEECCCCCEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1630321 [H]