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The map label for this gene is ubiE [C]

Identifier: 116622279

GI number: 116622279

Start: 4018836

End: 4019483

Strand: Reverse

Name: ubiE [C]

Synonym: Acid_3173

Alternate gene names: 116622279

Gene position: 4019483-4018836 (Counterclockwise)

Preceding gene: 116622281

Following gene: 116622278

Centisome position: 40.33

GC content: 57.1

Gene sequence:

>648_bases
ATGGCCGGCAGAAACTCACGGGTCAATCAATGCCAGAACCCGACCGGATGGCTGGGACGTTGGGTTCTGCGCAATATGAA
CTCGCGCCACTCCAAAGTTACCGATTGGGGCTTGTCGCACGCGTCGATAGGGAAACAGGACATCATCCTGGATGTAGGCT
GCGGCGGCGGCAGAACCGTGAGCAAGTTGGCTGCAATCGCCACCCAGGGCAAGGTCTGTGGCATCGATCATTCAACGGAG
AGCGTGGCCATGGCCGTGCGAACGAACAAGCAATGGATCGATCTTGCGCGCGTTGAGATTCGGGAGGCGTCCGTCTCCCG
GTTGCCATTTCCAGACGGCGTTTTTGATGTCGCCACGGCCGTCGAAACGCACTTCTGGTGGCCTGCTTTGGCGACGGATA
TGCGCGAAGTGTTGAGAGTCCTGAAACCGGGTGGCAGGCTGATCATCATCGCGGAAGTCTACAAAGGAGCAGAGTCCTTC
ACTTCAAAAGCTGCGGAGAAATACTCCCAAAAAACCGGTATGGCGCTGCTCAGCATCGAGGAGCATCGCGAACTATTCAC
GGATGCCGGCTACTCGGACGTTCAGGTCATTACGGATTCGCGCAAAGGGTGGATTTGCTGCATCGGGACCAAGATCTCAG
CCTCGTAG

Upstream 100 bases:

>100_bases
CCTCGGAGTTGGACGGGTCAAGGTACAGCAAAGACTTCGTTTGGCGGGCCAGGTGCCACAATAGCGCCTGGGTGTCCACT
CTTTGGCTGGGTGAACCGAT

Downstream 100 bases:

>100_bases
CGGCTGGCGGATTTCCGATCCGCCAGTTACACTGCCGTCATGAATCACCGGCGTGCTTTCTTACAGACCGTCGCGGGTCT
CGGCGTTGCCGCGCAAGCCG

Product: type 11 methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Methyltransferase; SAM-Dependent Methyltransferase; Methyltransferase UbiE/COQ5 Family; Methyl Transferase; SAM-Dependent Methyltransferase UbiE Family; UbiE/COQ5 Family Methlytransferase; Methyltransferase Domain-Containing Protein; Methylase Involved In Ubiquinone/Menaquinone Biosynthesis; UbiE/COQ5 Methyltransferase; Methyltransferase Domain Protein; Sam-Dependent Methyltransferase; C5-O-Methyltransferase; Multidrug Resistance Protein; Methyltransferase Domain Family; SAM Dependent Methyltransferase YrrH; UbiE/COQ5 Family Methyltransferase

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MAGRNSRVNQCQNPTGWLGRWVLRNMNSRHSKVTDWGLSHASIGKQDIILDVGCGGGRTVSKLAAIATQGKVCGIDHSTE
SVAMAVRTNKQWIDLARVEIREASVSRLPFPDGVFDVATAVETHFWWPALATDMREVLRVLKPGGRLIIIAEVYKGAESF
TSKAAEKYSQKTGMALLSIEEHRELFTDAGYSDVQVITDSRKGWICCIGTKISAS

Sequences:

>Translated_215_residues
MAGRNSRVNQCQNPTGWLGRWVLRNMNSRHSKVTDWGLSHASIGKQDIILDVGCGGGRTVSKLAAIATQGKVCGIDHSTE
SVAMAVRTNKQWIDLARVEIREASVSRLPFPDGVFDVATAVETHFWWPALATDMREVLRVLKPGGRLIIIAEVYKGAESF
TSKAAEKYSQKTGMALLSIEEHRELFTDAGYSDVQVITDSRKGWICCIGTKISAS
>Mature_214_residues
AGRNSRVNQCQNPTGWLGRWVLRNMNSRHSKVTDWGLSHASIGKQDIILDVGCGGGRTVSKLAAIATQGKVCGIDHSTES
VAMAVRTNKQWIDLARVEIREASVSRLPFPDGVFDVATAVETHFWWPALATDMREVLRVLKPGGRLIIIAEVYKGAESFT
SKAAEKYSQKTGMALLSIEEHRELFTDAGYSDVQVITDSRKGWICCIGTKISAS

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 23593; Mature: 23462

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRNSRVNQCQNPTGWLGRWVLRNMNSRHSKVTDWGLSHASIGKQDIILDVGCGGGRTV
CCCCCCCHHHCCCCHHHHHHHHHHCCCCCCCCCHHCCCCHHCCCCCEEEEEECCCCCHHH
SKLAAIATQGKVCGIDHSTESVAMAVRTNKQWIDLARVEIREASVSRLPFPDGVFDVATA
HHHHHHHHCCCEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VETHFWWPALATDMREVLRVLKPGGRLIIIAEVYKGAESFTSKAAEKYSQKTGMALLSIE
HHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHCCEEEEEHH
EHRELFTDAGYSDVQVITDSRKGWICCIGTKISAS
HHHHHHHCCCCCCEEEEECCCCCEEEEECCEECCC
>Mature Secondary Structure 
AGRNSRVNQCQNPTGWLGRWVLRNMNSRHSKVTDWGLSHASIGKQDIILDVGCGGGRTV
CCCCCCHHHCCCCHHHHHHHHHHCCCCCCCCCHHCCCCHHCCCCCEEEEEECCCCCHHH
SKLAAIATQGKVCGIDHSTESVAMAVRTNKQWIDLARVEIREASVSRLPFPDGVFDVATA
HHHHHHHHCCCEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VETHFWWPALATDMREVLRVLKPGGRLIIIAEVYKGAESFTSKAAEKYSQKTGMALLSIE
HHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHCCEEEEEHH
EHRELFTDAGYSDVQVITDSRKGWICCIGTKISAS
HHHHHHHCCCCCCEEEEECCCCCEEEEECCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA