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The map label for this gene is nahA [H]

Identifier: 116622194

GI number: 116622194

Start: 3902943

End: 3904991

Strand: Direct

Name: nahA [H]

Synonym: Acid_3086

Alternate gene names: 116622194

Gene position: 3902943-3904991 (Clockwise)

Preceding gene: 116622192

Following gene: 116622195

Centisome position: 39.16

GC content: 65.5

Gene sequence:

>2049_bases
ATGTTTCGGTGGACCCTTCTCATCACGATCGCCTGCGCGCCCATGGCGGCGGCTACGCCAGACCTGATGCCCTATCCGGC
AAAGGTGGCGCCGGGAGCAGGCTTCATGGCCATCGACTCAGGCTTTCGCGTGGCCCTCGCGGGCTTCTCCGATGCGCGCC
TCTCGGCCGCGGTCCGGCGTACCACCGACCGCGTCTTCCGCCAGACGGGTATCGTGCCTGCATCCGCCACCCGGCCGGCT
TTGACCATCGATTGCCGTTCGGCAGGGAGCCCGTGGCCGGTGCTCGGCGAGGACGAGTCCTACCAGCTCGATATAAAGGA
TGACCGCGCGCTGCTCTCGGCCGCGACCGTGACCGGCGCGCTCCGTGGGATGGCGACGTTCGTCCAGCTGATCGCCCCCG
GTCCGGAGGGCTTCCGCGTCCCCGCGATCCACATCGAAGACCGCCCTCGCTTCCCCTGGCGCGGTTTGATGATGGACGTC
GCCCGTCACTGGATGCCGCTGGAAGTTGTCCTGCGCAACCTGGACGCTATGGCCGCGGTCAAACTGAACGTCTTTCACTG
GCACCTTTCCGACGACCAGGGATTTCGCGTGGAAAGCAAGCTCTTCCCGCAGCTCCACAAGGCCGGCTCGGACGGTCACT
TCTATACCCAGGCCCAGATCCGCGAAGTGGTCGAATACGCCCGCGATCGCGGCATTCGCGTGATCCCGGAGTTCGACGTT
CCCGGCCACACCACCAGCTGGCTCGTCGGCATGCCGGAGCTGGCGAGCGCACCCGGACCTTATCAGATTCAACGGCGATG
GGGTATCTTCGAACCCACGCTCGACCCCACGCGGGAAGAGACCTACCGCGTGCTCGATGGTTTCTTCGGCGAAATGGCCG
CCCTCTTCCCCGACCGCTACTTCCACATCGGCGGCGACGAGGTCGAGGATGCCCAGTGGAAACAATCCGCCGCCATTCAG
GAATTCTGCCGCCTGCACCACCTCGCCAACAGCCGCGAGCTGCACGCCTACTTCAATCAGCGCGTGCAGGCTCTCGTCAA
GAAGCACGGGAAGAGCATGATTGGATGGGATGAGGTGCTGGCGCCTGGACTCGCCGGCGACACCGTGATCCAGTCCTGGC
GCGGCCCCGAGTCCCTCGCCGATGCCTCGCGCAAGGGTTATCGCGGCATCCTCTCTTCGGGCTATTACCTCGATCACCTT
CAGTCGGCCGGTACCCACTACGCGGTCGATCCGCTGGCTGGGACGGCGGGCGCGCTCGACGCCAACGGCGCCGCGCGCAT
CCTCGGCGGCGAGGCCTGCATGTGGGCGGAGTACGTCAGCGCGGAGACATTGGATTCCCGCATCTGGCCGCGCATGGCCG
CGATCGCCGAGCGCTTCTGGTCTCCGCGCGAGATCAATGACACGGCGGATATGTATGCGCGCCTGGAACCCGTGAGCCGC
GGCCTGCAATGGACCGGCCTGCGCCATCGCACAAACTATCAGCCGATGCTCGACCGCCTCGCGGGGACCGGCCCGGCCGA
ACCACTCAGAATTCTGGCCGACGCCTGCGAGGCCCTCGGAATCACGGTCCGCCGCGATGCGCGGAAGTACACCAGCCTGG
TGGACCTCAATCGGTTTGCCGATGCCGTGCGGCCCGAGAGCGTCTCCGTACACAACCTGGAACAATCGGCGCGCCGGCTC
GCTCCGGCGGACCTCGCCGCGCTTCGCGGAACCCTGCAGTCGTGGGCGCAGAATGACGCGCTCCTCGCTCCCGACGGCAA
TGTGTTCCTTCGCGAATTAACCGGGCTCTCGCGCCAGCTCAGCCAAGTGGGCGCGATCGGGCTCGAATCGCTCGACTATC
TGGAAACCGGGAAAACCGCTCCAGACAGCTGGGTCGCTCAAAAGAAACAGGCCCTAGCCGCCATGGACCAGCCCAGTGCC
GAGGTCATGTTGGCCGCTGTCCGTCCGGTGCGGCTCCTTGTCGAAGCCGCTTCCAAACGCAATCAGGGTGTCTTGAATCA
CGGTGTCTTGAATCAGGGTGTCATCAATCAGGGAGTCTTCAGGAGGTGA

Upstream 100 bases:

>100_bases
TTACGAACAACCTGCAACACCCTCCGCAACGGTTCCGAACTGGACGCGGGAGTACCGGCGGACGCACCATTCGGCAGAAC
CAAGAACAACAGGAACCAGC

Downstream 100 bases:

>100_bases
GTATGCATACAACGAGAATTAAGTGGTTGGCATTGCTCATGGCGATGCTCATAGCGACTTCGGCCGCACTGCTTGCGCAG
GACGCCAGCGGCGGAATCAC

Product: beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 682; Mature: 682

Protein sequence:

>682_residues
MFRWTLLITIACAPMAAATPDLMPYPAKVAPGAGFMAIDSGFRVALAGFSDARLSAAVRRTTDRVFRQTGIVPASATRPA
LTIDCRSAGSPWPVLGEDESYQLDIKDDRALLSAATVTGALRGMATFVQLIAPGPEGFRVPAIHIEDRPRFPWRGLMMDV
ARHWMPLEVVLRNLDAMAAVKLNVFHWHLSDDQGFRVESKLFPQLHKAGSDGHFYTQAQIREVVEYARDRGIRVIPEFDV
PGHTTSWLVGMPELASAPGPYQIQRRWGIFEPTLDPTREETYRVLDGFFGEMAALFPDRYFHIGGDEVEDAQWKQSAAIQ
EFCRLHHLANSRELHAYFNQRVQALVKKHGKSMIGWDEVLAPGLAGDTVIQSWRGPESLADASRKGYRGILSSGYYLDHL
QSAGTHYAVDPLAGTAGALDANGAARILGGEACMWAEYVSAETLDSRIWPRMAAIAERFWSPREINDTADMYARLEPVSR
GLQWTGLRHRTNYQPMLDRLAGTGPAEPLRILADACEALGITVRRDARKYTSLVDLNRFADAVRPESVSVHNLEQSARRL
APADLAALRGTLQSWAQNDALLAPDGNVFLRELTGLSRQLSQVGAIGLESLDYLETGKTAPDSWVAQKKQALAAMDQPSA
EVMLAAVRPVRLLVEAASKRNQGVLNHGVLNQGVINQGVFRR

Sequences:

>Translated_682_residues
MFRWTLLITIACAPMAAATPDLMPYPAKVAPGAGFMAIDSGFRVALAGFSDARLSAAVRRTTDRVFRQTGIVPASATRPA
LTIDCRSAGSPWPVLGEDESYQLDIKDDRALLSAATVTGALRGMATFVQLIAPGPEGFRVPAIHIEDRPRFPWRGLMMDV
ARHWMPLEVVLRNLDAMAAVKLNVFHWHLSDDQGFRVESKLFPQLHKAGSDGHFYTQAQIREVVEYARDRGIRVIPEFDV
PGHTTSWLVGMPELASAPGPYQIQRRWGIFEPTLDPTREETYRVLDGFFGEMAALFPDRYFHIGGDEVEDAQWKQSAAIQ
EFCRLHHLANSRELHAYFNQRVQALVKKHGKSMIGWDEVLAPGLAGDTVIQSWRGPESLADASRKGYRGILSSGYYLDHL
QSAGTHYAVDPLAGTAGALDANGAARILGGEACMWAEYVSAETLDSRIWPRMAAIAERFWSPREINDTADMYARLEPVSR
GLQWTGLRHRTNYQPMLDRLAGTGPAEPLRILADACEALGITVRRDARKYTSLVDLNRFADAVRPESVSVHNLEQSARRL
APADLAALRGTLQSWAQNDALLAPDGNVFLRELTGLSRQLSQVGAIGLESLDYLETGKTAPDSWVAQKKQALAAMDQPSA
EVMLAAVRPVRLLVEAASKRNQGVLNHGVLNQGVINQGVFRR
>Mature_682_residues
MFRWTLLITIACAPMAAATPDLMPYPAKVAPGAGFMAIDSGFRVALAGFSDARLSAAVRRTTDRVFRQTGIVPASATRPA
LTIDCRSAGSPWPVLGEDESYQLDIKDDRALLSAATVTGALRGMATFVQLIAPGPEGFRVPAIHIEDRPRFPWRGLMMDV
ARHWMPLEVVLRNLDAMAAVKLNVFHWHLSDDQGFRVESKLFPQLHKAGSDGHFYTQAQIREVVEYARDRGIRVIPEFDV
PGHTTSWLVGMPELASAPGPYQIQRRWGIFEPTLDPTREETYRVLDGFFGEMAALFPDRYFHIGGDEVEDAQWKQSAAIQ
EFCRLHHLANSRELHAYFNQRVQALVKKHGKSMIGWDEVLAPGLAGDTVIQSWRGPESLADASRKGYRGILSSGYYLDHL
QSAGTHYAVDPLAGTAGALDANGAARILGGEACMWAEYVSAETLDSRIWPRMAAIAERFWSPREINDTADMYARLEPVSR
GLQWTGLRHRTNYQPMLDRLAGTGPAEPLRILADACEALGITVRRDARKYTSLVDLNRFADAVRPESVSVHNLEQSARRL
APADLAALRGTLQSWAQNDALLAPDGNVFLRELTGLSRQLSQVGAIGLESLDYLETGKTAPDSWVAQKKQALAAMDQPSA
EVMLAAVRPVRLLVEAASKRNQGVLNHGVLNQGVINQGVFRR

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI189181666, Length=412, Percent_Identity=41.504854368932, Blast_Score=303, Evalue=3e-82,
Organism=Homo sapiens, GI4504373, Length=411, Percent_Identity=39.9026763990268, Blast_Score=298, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17569815, Length=438, Percent_Identity=32.8767123287671, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI281365639, Length=431, Percent_Identity=32.0185614849188, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24657474, Length=431, Percent_Identity=32.0185614849188, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24657468, Length=431, Percent_Identity=32.0185614849188, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17647501, Length=431, Percent_Identity=32.0185614849188, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17933586, Length=477, Percent_Identity=31.2368972746331, Blast_Score=185, Evalue=8e-47,
Organism=Drosophila melanogaster, GI45551090, Length=444, Percent_Identity=30.8558558558559, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24653074, Length=422, Percent_Identity=31.5165876777251, Blast_Score=164, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 75249; Mature: 75249

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRWTLLITIACAPMAAATPDLMPYPAKVAPGAGFMAIDSGFRVALAGFSDARLSAAVRR
CEEEEEEEEEHHCCHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCHHHHHHHHHH
TTDRVFRQTGIVPASATRPALTIDCRSAGSPWPVLGEDESYQLDIKDDRALLSAATVTGA
HHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHH
LRGMATFVQLIAPGPEGFRVPAIHIEDRPRFPWRGLMMDVARHWMPLEVVLRNLDAMAAV
HHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHEE
KLNVFHWHLSDDQGFRVESKLFPQLHKAGSDGHFYTQAQIREVVEYARDRGIRVIPEFDV
EEEEEEEEECCCCCCEEHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCCCEEEECCCC
PGHTTSWLVGMPELASAPGPYQIQRRWGIFEPTLDPTREETYRVLDGFFGEMAALFPDRY
CCCCCHHEECCHHHHCCCCCCEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCE
FHIGGDEVEDAQWKQSAAIQEFCRLHHLANSRELHAYFNQRVQALVKKHGKSMIGWDEVL
EECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
APGLAGDTVIQSWRGPESLADASRKGYRGILSSGYYLDHLQSAGTHYAVDPLAGTAGALD
CCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEECCCCCCCCCCC
ANGAARILGGEACMWAEYVSAETLDSRIWPRMAAIAERFWSPREINDTADMYARLEPVSR
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
GLQWTGLRHRTNYQPMLDRLAGTGPAEPLRILADACEALGITVRRDARKYTSLVDLNRFA
CCEECCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
DAVRPESVSVHNLEQSARRLAPADLAALRGTLQSWAQNDALLAPDGNVFLRELTGLSRQL
HHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHH
SQVGAIGLESLDYLETGKTAPDSWVAQKKQALAAMDQPSAEVMLAAVRPVRLLVEAASKR
HHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
NQGVLNHGVLNQGVINQGVFRR
CCCCHHCCCCCCCHHCCCCCCC
>Mature Secondary Structure
MFRWTLLITIACAPMAAATPDLMPYPAKVAPGAGFMAIDSGFRVALAGFSDARLSAAVRR
CEEEEEEEEEHHCCHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCHHHHHHHHHH
TTDRVFRQTGIVPASATRPALTIDCRSAGSPWPVLGEDESYQLDIKDDRALLSAATVTGA
HHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHH
LRGMATFVQLIAPGPEGFRVPAIHIEDRPRFPWRGLMMDVARHWMPLEVVLRNLDAMAAV
HHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHEE
KLNVFHWHLSDDQGFRVESKLFPQLHKAGSDGHFYTQAQIREVVEYARDRGIRVIPEFDV
EEEEEEEEECCCCCCEEHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCCCEEEECCCC
PGHTTSWLVGMPELASAPGPYQIQRRWGIFEPTLDPTREETYRVLDGFFGEMAALFPDRY
CCCCCHHEECCHHHHCCCCCCEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCE
FHIGGDEVEDAQWKQSAAIQEFCRLHHLANSRELHAYFNQRVQALVKKHGKSMIGWDEVL
EECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
APGLAGDTVIQSWRGPESLADASRKGYRGILSSGYYLDHLQSAGTHYAVDPLAGTAGALD
CCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEECCCCCCCCCCC
ANGAARILGGEACMWAEYVSAETLDSRIWPRMAAIAERFWSPREINDTADMYARLEPVSR
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
GLQWTGLRHRTNYQPMLDRLAGTGPAEPLRILADACEALGITVRRDARKYTSLVDLNRFA
CCEECCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
DAVRPESVSVHNLEQSARRLAPADLAALRGTLQSWAQNDALLAPDGNVFLRELTGLSRQL
HHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHH
SQVGAIGLESLDYLETGKTAPDSWVAQKKQALAAMDQPSAEVMLAAVRPVRLLVEAASKR
HHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
NQGVLNHGVLNQGVINQGVFRR
CCCCHHCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]