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The map label for this gene is xylA

Identifier: 116622150

GI number: 116622150

Start: 3839679

End: 3840995

Strand: Reverse

Name: xylA

Synonym: Acid_3042

Alternate gene names: 116622150

Gene position: 3840995-3839679 (Counterclockwise)

Preceding gene: 116622151

Following gene: 116622143

Centisome position: 38.54

GC content: 58.85

Gene sequence:

>1317_bases
ATGACAGAGTCTTACTTCGCCAGTATCGCGCCGATCGAATTTGAGGGTGCCGCGTCAGAGAACCCGCTCGCTTATCGCTA
TTACGACAAGAACCGCGTCGTTCTCGGCAAGAGGATGGAGGACCATCTTCGGATGGCGGTCTGCTACTGGCACACGTTCT
GCAGCGAGGGCGCCGATATGTTCGGCCCCGGCACTTTCCACCGACCCTGGCACATTGGTCCGATGGACCAGGCGCATGCG
GAACATAAGCTAAACGAAGCTTTCGAGTTTTTCACCCGGCTGGGACTTCCGTTTTTCTGCTTTCACGATACGGATGTGAT
GGCCGAGGCGCACACGATCCGCGAGCACGTAGACAATCTGGCGCGCATCGGAGATCGAATTCAGGAAAAGATGGCGGCCA
CGGGAGTGAAGCTGCTTTGGGGCACGGCGAATCTATTCAGCCACCCGCGCTACATGGCGGGCGCGGCATCCAACCCGGAT
CCGGATGTCTTCCGATTTGCAGCAACACAGGTGCGGCACTGCATGGACCTGACGAAACGGCTTGGCGGCCAGAACTACGT
GCTGTGGGGCGGGCGCGAGGGGTACGATTCACTGCTGAATACCGATCTCAAGCAGGAGAAGGCGCAGCTTGGCCGCTTCT
TGAAGATGGTGATTGAGCACAAGCACAAGATTGGGTTTTCGGGAACGATTCTGATCGAGCCGAAGCCGCACGAACCCACA
AAGCATCAGTACGATTTTGATGTTGAGACTGTCTATAGCTTTCTGGTCGCCAACGGATTGGAAAAGGAAGTGAAGCTGAA
TATCGAGGCGAACCACGCGACCCTGGCGGGCCACAGCTTCGAGCATGAGATCGCGACCGCGGTGGCGCTTGGGGTGTTCG
GGTCGATCGATATGAATCGGGGCGATCCGCAGAATGGATGGGACACGGATCAGTTCCCGAACGACGTTCGCGAGATTACG
ACCGCGCTCTACTACATCCTGCTGGGAGGAGGCTTCACGACGGGCGGCAATAACTTCGACGCGAAGGTCAGGCGACAGAG
CTTCGAACCGGCCGATTTATTTTACGCACACGTCGGGGCGGTGGACACGGTGGCGCAGGGGTTGATCAACGCCGCCGCGA
TGATCGAGGGCGGACAACTCGCGGGAATCGTCAAGGAGCGATATGCTGGATGGCAGGGCGAACTCGGCCGCGCCATTCTG
GACGGCAAGATGTCGCTGGAGGCGTTATCGGATGGAGCGGTCGCGGAGGGCATCACGCCGCGGCCCCGGTCCGGCAGGCA
GGAGATGATCGAAAATCTGGTGGGCAGATATCTGTGA

Upstream 100 bases:

>100_bases
CACAGTGCGGGCGGGCCGGTAGCAGAGATCGCCTGCGGTAACGGAATTAGTTGCGGACTGCAACAAAATCTGGTACTTGT
CCTTTTGGGAGATTTATTGA

Downstream 100 bases:

>100_bases
GCCGGGATGGACCGGCCAAAGCGGCCGGTCCTACTCAGTTGCCGGCGTAGAAACTCGTACGACCTACGCAGGGTGGGGCT
CGCCTAGAATGCAGCGCACG

Product: xylose isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MTESYFASIAPIEFEGAASENPLAYRYYDKNRVVLGKRMEDHLRMAVCYWHTFCSEGADMFGPGTFHRPWHIGPMDQAHA
EHKLNEAFEFFTRLGLPFFCFHDTDVMAEAHTIREHVDNLARIGDRIQEKMAATGVKLLWGTANLFSHPRYMAGAASNPD
PDVFRFAATQVRHCMDLTKRLGGQNYVLWGGREGYDSLLNTDLKQEKAQLGRFLKMVIEHKHKIGFSGTILIEPKPHEPT
KHQYDFDVETVYSFLVANGLEKEVKLNIEANHATLAGHSFEHEIATAVALGVFGSIDMNRGDPQNGWDTDQFPNDVREIT
TALYYILLGGGFTTGGNNFDAKVRRQSFEPADLFYAHVGAVDTVAQGLINAAAMIEGGQLAGIVKERYAGWQGELGRAIL
DGKMSLEALSDGAVAEGITPRPRSGRQEMIENLVGRYL

Sequences:

>Translated_438_residues
MTESYFASIAPIEFEGAASENPLAYRYYDKNRVVLGKRMEDHLRMAVCYWHTFCSEGADMFGPGTFHRPWHIGPMDQAHA
EHKLNEAFEFFTRLGLPFFCFHDTDVMAEAHTIREHVDNLARIGDRIQEKMAATGVKLLWGTANLFSHPRYMAGAASNPD
PDVFRFAATQVRHCMDLTKRLGGQNYVLWGGREGYDSLLNTDLKQEKAQLGRFLKMVIEHKHKIGFSGTILIEPKPHEPT
KHQYDFDVETVYSFLVANGLEKEVKLNIEANHATLAGHSFEHEIATAVALGVFGSIDMNRGDPQNGWDTDQFPNDVREIT
TALYYILLGGGFTTGGNNFDAKVRRQSFEPADLFYAHVGAVDTVAQGLINAAAMIEGGQLAGIVKERYAGWQGELGRAIL
DGKMSLEALSDGAVAEGITPRPRSGRQEMIENLVGRYL
>Mature_437_residues
TESYFASIAPIEFEGAASENPLAYRYYDKNRVVLGKRMEDHLRMAVCYWHTFCSEGADMFGPGTFHRPWHIGPMDQAHAE
HKLNEAFEFFTRLGLPFFCFHDTDVMAEAHTIREHVDNLARIGDRIQEKMAATGVKLLWGTANLFSHPRYMAGAASNPDP
DVFRFAATQVRHCMDLTKRLGGQNYVLWGGREGYDSLLNTDLKQEKAQLGRFLKMVIEHKHKIGFSGTILIEPKPHEPTK
HQYDFDVETVYSFLVANGLEKEVKLNIEANHATLAGHSFEHEIATAVALGVFGSIDMNRGDPQNGWDTDQFPNDVREITT
ALYYILLGGGFTTGGNNFDAKVRRQSFEPADLFYAHVGAVDTVAQGLINAAAMIEGGQLAGIVKERYAGWQGELGRAILD
GKMSLEALSDGAVAEGITPRPRSGRQEMIENLVGRYL

Specific function: Unknown

COG id: COG2115

COG function: function code G; Xylose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xylose isomerase family

Homologues:

Organism=Escherichia coli, GI1789988, Length=436, Percent_Identity=61.4678899082569, Blast_Score=568, Evalue=1e-163,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XYLA_SOLUE (Q022S9)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_824306.1
- STRING:   Q022S9
- GeneID:   4428760
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_3042
- NMPDR:   fig|234267.9.peg.2886
- eggNOG:   COG2115
- HOGENOM:   HBG297199
- OMA:   LLGWDTD
- PhylomeDB:   Q022S9
- ProtClustDB:   PRK05474
- GO:   GO:0005737
- HAMAP:   MF_00455
- InterPro:   IPR013022
- InterPro:   IPR012307
- InterPro:   IPR013452
- InterPro:   IPR001998
- Gene3D:   G3DSA:3.20.20.150
- PRINTS:   PR00688
- TIGRFAMs:   TIGR02630

Pfam domain/function: PF01261 AP_endonuc_2; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =5.3.1.5

Molecular weight: Translated: 48879; Mature: 48748

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS51415 XYLOSE_ISOMERASE; PS00172 XYLOSE_ISOMERASE_1

Important sites: ACT_SITE 102-102 ACT_SITE 105-105

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESYFASIAPIEFEGAASENPLAYRYYDKNRVVLGKRMEDHLRMAVCYWHTFCSEGADM
CCCCHHEEECCEEECCCCCCCCEEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHCCCCC
FGPGTFHRPWHIGPMDQAHAEHKLNEAFEFFTRLGLPFFCFHDTDVMAEAHTIREHVDNL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHH
ARIGDRIQEKMAATGVKLLWGTANLFSHPRYMAGAASNPDPDVFRFAATQVRHCMDLTKR
HHHHHHHHHHHHHCCHHEEEECHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LGGQNYVLWGGREGYDSLLNTDLKQEKAQLGRFLKMVIEHKHKIGFSGTILIEPKPHEPT
HCCCEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
KHQYDFDVETVYSFLVANGLEKEVKLNIEANHATLAGHSFEHEIATAVALGVFGSIDMNR
CCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCEEECCCCHHHHHHHHHHHHHHCCCCCCC
GDPQNGWDTDQFPNDVREITTALYYILLGGGFTTGGNNFDAKVRRQSFEPADLFYAHVGA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHH
VDTVAQGLINAAAMIEGGQLAGIVKERYAGWQGELGRAILDGKMSLEALSDGAVAEGITP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHCCCCHHCCCCC
RPRSGRQEMIENLVGRYL
CCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TESYFASIAPIEFEGAASENPLAYRYYDKNRVVLGKRMEDHLRMAVCYWHTFCSEGADM
CCCHHEEECCEEECCCCCCCCEEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHCCCCC
FGPGTFHRPWHIGPMDQAHAEHKLNEAFEFFTRLGLPFFCFHDTDVMAEAHTIREHVDNL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHH
ARIGDRIQEKMAATGVKLLWGTANLFSHPRYMAGAASNPDPDVFRFAATQVRHCMDLTKR
HHHHHHHHHHHHHCCHHEEEECHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LGGQNYVLWGGREGYDSLLNTDLKQEKAQLGRFLKMVIEHKHKIGFSGTILIEPKPHEPT
HCCCEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
KHQYDFDVETVYSFLVANGLEKEVKLNIEANHATLAGHSFEHEIATAVALGVFGSIDMNR
CCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCEEECCCCHHHHHHHHHHHHHHCCCCCCC
GDPQNGWDTDQFPNDVREITTALYYILLGGGFTTGGNNFDAKVRRQSFEPADLFYAHVGA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHH
VDTVAQGLINAAAMIEGGQLAGIVKERYAGWQGELGRAILDGKMSLEALSDGAVAEGITP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHCCCCHHCCCCC
RPRSGRQEMIENLVGRYL
CCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA