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The map label for this gene is ppa [H]

Identifier: 116622142

GI number: 116622142

Start: 3834299

End: 3834841

Strand: Reverse

Name: ppa [H]

Synonym: Acid_3034

Alternate gene names: 116622142

Gene position: 3834841-3834299 (Counterclockwise)

Preceding gene: 116622143

Following gene: 116622139

Centisome position: 38.48

GC content: 51.93

Gene sequence:

>543_bases
ATGGCCGATCTGACAACCCTTCCAAATCAACTTGATCCCAGTAATTCAACCTGCCGCGCGATCATTGAAACGCCGAAGGG
GTCCCGCAACAAGTTCGATTACGATCCGGACTCCAATCTCTTCATACTCGCCGGGCTGCTGCCGGAGGGAATGATGTTCC
CGTTCGATTTTGGGTTTATTCCTTCCACTCACGGAGAGGACGGCGATCCACTCGACATTATGGTGTTAATGGACGCTCCT
GCTCACGTCGGCTGTTTGATCGACGTGCGAATCATCGGAATCATCGAGGCCGACCAAACGCAAGACGGAAAAACCGAGAG
AAACAGCCGGATTCTAGGCGCAGCGATCCATTCCTACGAACACGAGAATCTCATGACTGTATCAGACGTGAGTAAGACCT
TGTTATCGCAGGTCGAAGAGTTCTTCGTGTCCTATAACAAACAGCGCGGCAAGAGATTCAGGATCACAGACACCGGCGGT
CCGAAAAAAGCTCTGCGCTATCTCAAGAAGGGGATCCGGGCTTATCAAGACGCGAAGAAGTGA

Upstream 100 bases:

>100_bases
GGGCGCAGAAGTGGGTGTTTCCGAACAGATCGACCCGAGAGAGTCCCCTGGTTTGTCCTGGGTGGAGGATCTTCTGCGGA
CTCTTAGGATAATGAGTAAC

Downstream 100 bases:

>100_bases
GGGGCGGAGCATTCAACGCTGTACTTTTCGATTAGCGGAGACGCCTTTCGAACGGCTTGCCAAATTGTAGTACACAATGG
AACACTGTTTCGCCATCCGA

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MADLTTLPNQLDPSNSTCRAIIETPKGSRNKFDYDPDSNLFILAGLLPEGMMFPFDFGFIPSTHGEDGDPLDIMVLMDAP
AHVGCLIDVRIIGIIEADQTQDGKTERNSRILGAAIHSYEHENLMTVSDVSKTLLSQVEEFFVSYNKQRGKRFRITDTGG
PKKALRYLKKGIRAYQDAKK

Sequences:

>Translated_180_residues
MADLTTLPNQLDPSNSTCRAIIETPKGSRNKFDYDPDSNLFILAGLLPEGMMFPFDFGFIPSTHGEDGDPLDIMVLMDAP
AHVGCLIDVRIIGIIEADQTQDGKTERNSRILGAAIHSYEHENLMTVSDVSKTLLSQVEEFFVSYNKQRGKRFRITDTGG
PKKALRYLKKGIRAYQDAKK
>Mature_179_residues
ADLTTLPNQLDPSNSTCRAIIETPKGSRNKFDYDPDSNLFILAGLLPEGMMFPFDFGFIPSTHGEDGDPLDIMVLMDAPA
HVGCLIDVRIIGIIEADQTQDGKTERNSRILGAAIHSYEHENLMTVSDVSKTLLSQVEEFFVSYNKQRGKRFRITDTGGP
KKALRYLKKGIRAYQDAKK

Specific function: Hydrolyzes PPi generated in anabolic reactions [H]

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

None

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 20082; Mature: 19951

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLTTLPNQLDPSNSTCRAIIETPKGSRNKFDYDPDSNLFILAGLLPEGMMFPFDFGFI
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCC
PSTHGEDGDPLDIMVLMDAPAHVGCLIDVRIIGIIEADQTQDGKTERNSRILGAAIHSYE
CCCCCCCCCCEEEEEEECCCCCCEEEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHC
HENLMTVSDVSKTLLSQVEEFFVSYNKQRGKRFRITDTGGPKKALRYLKKGIRAYQDAKK
CCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADLTTLPNQLDPSNSTCRAIIETPKGSRNKFDYDPDSNLFILAGLLPEGMMFPFDFGFI
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCC
PSTHGEDGDPLDIMVLMDAPAHVGCLIDVRIIGIIEADQTQDGKTERNSRILGAAIHSYE
CCCCCCCCCCEEEEEEECCCCCCEEEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHC
HENLMTVSDVSKTLLSQVEEFFVSYNKQRGKRFRITDTGGPKKALRYLKKGIRAYQDAKK
CCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]