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The map label for this gene is ppa [H]

Identifier: 116622117

GI number: 116622117

Start: 3803375

End: 3803953

Strand: Direct

Name: ppa [H]

Synonym: Acid_3005

Alternate gene names: 116622117

Gene position: 3803375-3803953 (Clockwise)

Preceding gene: 116622116

Following gene: 116622118

Centisome position: 38.16

GC content: 55.79

Gene sequence:

>579_bases
GTGAGGCTCCCTTTTTTTTATAAGGAGCAGATTGTGAAGGCTCTCAAGGCATTCGACCAGAAAAGCGGTCATTTCCACGT
CATCATCGATACACCGAAGGGACATCGGAACAAATACCATTACGAGGAAGATAAGGACCTGTTCCTGCTCAAATCCGTAT
TACCGGCCGGGATGGTGTTTCCGTTCGACTTCGGCTTTGTTCCCGGCACGCATGGGGACGACGGAGACCCGCTCGATATT
TTAGTGCTGACCGACGAGCCGGCGATTCAGGGAAGCCTGGTGATGACCCGCCTGCTGGCCGTTATCGAGGCCGAACAGAC
CGAGCAGGGTGAAACCAACCGCAACGACCGGCTGATCGGGATTGCCGCCGCGTCCCGTGAGTACCAATCGGTGGAATCGC
TGGATCAGCTGAATCCCAATCTTATAGAGGAGATCAAGCATTTCTTCGTCACTTACAACGAGTTGTCAGGGAAGGCGTTC
CGACCGCTCGGCGCAGCTGGGGCGGATCGTGCCCGCAAATTGATTGAAAGCGCCGCCAAACGTGCCCCGAGATCTGCAGG
CCGGGGCAAACGCAGATAA

Upstream 100 bases:

>100_bases
TCGGTTGGCTCGCTTAATGGACTTGCCGGACGCCAGTTCCAAGTGGGCGCCCGGGTCCTGTTCTAGGCAAAACCGACTCG
CCTAGTGTGAGGGAGCCTCT

Downstream 100 bases:

>100_bases
GCCTGCTGATAGATATGCACGGCTTCACAAGGGACTCCCATTTGCGGTGTGAAGCTCATCCAAGGAGAAACTTGCATGTC
AGATCGTGAACTCAAAGGAA

Product: inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MRLPFFYKEQIVKALKAFDQKSGHFHVIIDTPKGHRNKYHYEEDKDLFLLKSVLPAGMVFPFDFGFVPGTHGDDGDPLDI
LVLTDEPAIQGSLVMTRLLAVIEAEQTEQGETNRNDRLIGIAAASREYQSVESLDQLNPNLIEEIKHFFVTYNELSGKAF
RPLGAAGADRARKLIESAAKRAPRSAGRGKRR

Sequences:

>Translated_192_residues
MRLPFFYKEQIVKALKAFDQKSGHFHVIIDTPKGHRNKYHYEEDKDLFLLKSVLPAGMVFPFDFGFVPGTHGDDGDPLDI
LVLTDEPAIQGSLVMTRLLAVIEAEQTEQGETNRNDRLIGIAAASREYQSVESLDQLNPNLIEEIKHFFVTYNELSGKAF
RPLGAAGADRARKLIESAAKRAPRSAGRGKRR
>Mature_192_residues
MRLPFFYKEQIVKALKAFDQKSGHFHVIIDTPKGHRNKYHYEEDKDLFLLKSVLPAGMVFPFDFGFVPGTHGDDGDPLDI
LVLTDEPAIQGSLVMTRLLAVIEAEQTEQGETNRNDRLIGIAAASREYQSVESLDQLNPNLIEEIKHFFVTYNELSGKAF
RPLGAAGADRARKLIESAAKRAPRSAGRGKRR

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=163, Percent_Identity=27.6073619631902, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 21539; Mature: 21539

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLPFFYKEQIVKALKAFDQKSGHFHVIIDTPKGHRNKYHYEEDKDLFLLKSVLPAGMVF
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCEEC
PFDFGFVPGTHGDDGDPLDILVLTDEPAIQGSLVMTRLLAVIEAEQTEQGETNRNDRLIG
CCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
IAAASREYQSVESLDQLNPNLIEEIKHFFVTYNELSGKAFRPLGAAGADRARKLIESAAK
EEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
RAPRSAGRGKRR
HCCCCCCCCCCC
>Mature Secondary Structure
MRLPFFYKEQIVKALKAFDQKSGHFHVIIDTPKGHRNKYHYEEDKDLFLLKSVLPAGMVF
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCEEC
PFDFGFVPGTHGDDGDPLDILVLTDEPAIQGSLVMTRLLAVIEAEQTEQGETNRNDRLIG
CCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
IAAASREYQSVESLDQLNPNLIEEIKHFFVTYNELSGKAFRPLGAAGADRARKLIESAAK
EEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
RAPRSAGRGKRR
HCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]