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The map label for this gene is yycF [H]

Identifier: 116621521

GI number: 116621521

Start: 3062225

End: 3062962

Strand: Direct

Name: yycF [H]

Synonym: Acid_2403

Alternate gene names: 116621521

Gene position: 3062225-3062962 (Clockwise)

Preceding gene: 116621520

Following gene: 116621522

Centisome position: 30.73

GC content: 63.96

Gene sequence:

>738_bases
ATGAGCCGGATTCTGGTGGTCGAAGACGAACTGCACCTGGCCGAGGGACTGCGGTTCAACCTGGAGGCGGAGGGATACCA
GGTCGAGGTGGTGGAGACCGGTGAAGCGGCGCTGGAGCGGCTGGTGCCGGGGGAGCCGCGGTTCGACGTGGTGGTGCTGG
ACGTGATGCTGCCCGGCAAGGACGGCTTCACGGTGATGAGCGAGATGCGCCATGCCGGCCAGTTCATTCCCACGCTGATG
CTCACGGCGCGCGGCCACGCGGAGGATATTCTGCACGGCTTTGCGGCGGGGGCTGACGATTACCTGACCAAGCCTTTCGA
ACTCGCCATCCTGATCGCACGAATTCGCGGGCTGCTGCGACGGCGCGAATGGTTGAATGCGTCGGTGGCTCCGGTTCCGG
CGCCGGCGGAGCCGAGTCCCGATACCTTTTCCTTCGGCGATAAGTCGGTGCACTTCGACCTGCTGGAACTGCACGTGCGC
GAGCAGGTGTTTCCGTTGACGCTGATGGAAGCCAACCTGCTGCGCTACCTGATTCAACACGAAGGCAAACCGGTATCGCG
GAAAGCCATGCTGGAAGAAGTCTGGGGACTGCACGAGGACACCGACACGCGCGCGATCGATAACTTCATCGTGCGCCTGC
GGCGCTACGTGGAGGAGGAGCCGACCAAGCCGCGGCACCTGCTGACGGTGCGCGGAGTGGGTTACCGCTTCGTGGCGTCG
CCGGTGAAGAAATCGTGA

Upstream 100 bases:

>100_bases
TTGTGCGCTCGGTGGCCAAGCGACACGGTGGGCGGGCGTGGGCGGAGAGCGAGGGGCCGGGCCTGGGCAGCACGTTCGCG
CTGCAACTTCCGATTGCGCC

Downstream 100 bases:

>100_bases
TGCGGCGCGCGGTGGGGACGCTGTTGTCAGCGGCGCTGCTGGTGGCGCTCGTCTTCGCCGCGCCGGCTGAGTTTCACTTT
GTGCTGCTGGGAGACCGCAC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MSRILVVEDELHLAEGLRFNLEAEGYQVEVVETGEAALERLVPGEPRFDVVVLDVMLPGKDGFTVMSEMRHAGQFIPTLM
LTARGHAEDILHGFAAGADDYLTKPFELAILIARIRGLLRRREWLNASVAPVPAPAEPSPDTFSFGDKSVHFDLLELHVR
EQVFPLTLMEANLLRYLIQHEGKPVSRKAMLEEVWGLHEDTDTRAIDNFIVRLRRYVEEEPTKPRHLLTVRGVGYRFVAS
PVKKS

Sequences:

>Translated_245_residues
MSRILVVEDELHLAEGLRFNLEAEGYQVEVVETGEAALERLVPGEPRFDVVVLDVMLPGKDGFTVMSEMRHAGQFIPTLM
LTARGHAEDILHGFAAGADDYLTKPFELAILIARIRGLLRRREWLNASVAPVPAPAEPSPDTFSFGDKSVHFDLLELHVR
EQVFPLTLMEANLLRYLIQHEGKPVSRKAMLEEVWGLHEDTDTRAIDNFIVRLRRYVEEEPTKPRHLLTVRGVGYRFVAS
PVKKS
>Mature_244_residues
SRILVVEDELHLAEGLRFNLEAEGYQVEVVETGEAALERLVPGEPRFDVVVLDVMLPGKDGFTVMSEMRHAGQFIPTLML
TARGHAEDILHGFAAGADDYLTKPFELAILIARIRGLLRRREWLNASVAPVPAPAEPSPDTFSFGDKSVHFDLLELHVRE
QVFPLTLMEANLLRYLIQHEGKPVSRKAMLEEVWGLHEDTDTRAIDNFIVRLRRYVEEEPTKPRHLLTVRGVGYRFVASP
VKKS

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=36.4406779661017, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1786911, Length=238, Percent_Identity=33.6134453781513, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082012, Length=242, Percent_Identity=32.6446280991736, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1786784, Length=235, Percent_Identity=34.468085106383, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1786599, Length=237, Percent_Identity=35.4430379746835, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787375, Length=236, Percent_Identity=31.7796610169492, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI2367329, Length=245, Percent_Identity=36.734693877551, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1790552, Length=238, Percent_Identity=34.453781512605, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790860, Length=236, Percent_Identity=34.7457627118644, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788394, Length=245, Percent_Identity=32.2448979591837, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790863, Length=242, Percent_Identity=30.5785123966942, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789402, Length=235, Percent_Identity=31.063829787234, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI145693140, Length=244, Percent_Identity=30.327868852459, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787229, Length=240, Percent_Identity=27.9166666666667, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=31.4814814814815, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790437, Length=131, Percent_Identity=32.0610687022901, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27716; Mature: 27585

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRILVVEDELHLAEGLRFNLEAEGYQVEVVETGEAALERLVPGEPRFDVVVLDVMLPGK
CCCEEEEECCHHHHCCCEEEEECCCEEEEEEECCHHHHHHHCCCCCCEEEEEEEEEECCC
DGFTVMSEMRHAGQFIPTLMLTARGHAEDILHGFAAGADDYLTKPFELAILIARIRGLLR
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHH
RREWLNASVAPVPAPAEPSPDTFSFGDKSVHFDLLELHVREQVFPLTLMEANLLRYLIQH
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGKPVSRKAMLEEVWGLHEDTDTRAIDNFIVRLRRYVEEEPTKPRHLLTVRGVGYRFVAS
CCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECC
PVKKS
CCCCC
>Mature Secondary Structure 
SRILVVEDELHLAEGLRFNLEAEGYQVEVVETGEAALERLVPGEPRFDVVVLDVMLPGK
CCEEEEECCHHHHCCCEEEEECCCEEEEEEECCHHHHHHHCCCCCCEEEEEEEEEECCC
DGFTVMSEMRHAGQFIPTLMLTARGHAEDILHGFAAGADDYLTKPFELAILIARIRGLLR
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHH
RREWLNASVAPVPAPAEPSPDTFSFGDKSVHFDLLELHVREQVFPLTLMEANLLRYLIQH
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGKPVSRKAMLEEVWGLHEDTDTRAIDNFIVRLRRYVEEEPTKPRHLLTVRGVGYRFVAS
CCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECC
PVKKS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]