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The map label for this gene is yycG [H]

Identifier: 116621520

GI number: 116621520

Start: 3061338

End: 3062228

Strand: Direct

Name: yycG [H]

Synonym: Acid_2402

Alternate gene names: 116621520

Gene position: 3061338-3062228 (Clockwise)

Preceding gene: 116621519

Following gene: 116621521

Centisome position: 30.72

GC content: 63.3

Gene sequence:

>891_bases
ATGGACCTGAGCGGGCGGCGCAAATCGGTAGCGGGATCGATTGCGCTGGCCGTGGGGCTGATCTCGGTCCTGATTGTTCT
CTACATCGGGTACGTGCTTTTGAACTGGCGGACGGGCATTCTGCTGATGATGGGCGTTCTGCTGGTGCTGATGATCATCT
GCGGCATCCTGCTGAACACGGTATTCCTGGTGACTGAAATCCGCCGCAACGAACAGCACGACGCCTTCATCAACGCGGTC
ACGCACGAGCTGAAGACGCCCGTGGCATCGATCCGGCTTTATCTGGAGACGCTGCAGACGCGGCCGGTGGACGAGGCGAA
GCGCAAAGAGTTTTACAAGATCATGCTGGACGATAGCGACCGGCTGCTCAGCACCATCGAACAGGTGCTGCGGACGGGTC
GCGTGGGCAGCACGTCGCACCACCTGAACCGCACGCGCATCGATCTGGATGAAGTGGTGCGGACGTCGGTGGAGCGGGTG
CGGCTGCTGCACAAAGTTTCGGCCGATGCGCTCTGCTACCAACCGTGCGGTCCGGCGGCGGTGATGGGCGACCTGGACGA
AGTGCGCGCGGCGGTTACCAACCTGGTGGACAATGCGGTGAAGTACTCGGGGCCGGAGGTCCACGTGGTGGTGGAGACGG
AGCGGGTGGACCGCTTCGTGATCGTGCGGGTGAAGGATACGGGTCCGGGAATTCCGAAAACGGAATTGAAGCGCGTTTTC
CGAAGATTTTACCGGGTGCCCGGGCCGCTGGCCTCGCGCGTGAAGGGGACCGGGTTGGGTCTGTACATTGTGCGCTCGGT
GGCCAAGCGACACGGTGGGCGGGCGTGGGCGGAGAGCGAGGGGCCGGGCCTGGGCAGCACGTTCGCGCTGCAACTTCCGA
TTGCGCCATGA

Upstream 100 bases:

>100_bases
TTCGTGACAAATGCCAGTAGCACAGGGCGGCGAGCTGGGGTCCTGGCTCTGATGAGGGGCGAGCACAGTGATACAAATGC
AGGGCTGCTAATCTGAAGGT

Downstream 100 bases:

>100_bases
GCCGGATTCTGGTGGTCGAAGACGAACTGCACCTGGCCGAGGGACTGCGGTTCAACCTGGAGGCGGAGGGATACCAGGTC
GAGGTGGTGGAGACCGGTGA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDLSGRRKSVAGSIALAVGLISVLIVLYIGYVLLNWRTGILLMMGVLLVLMIICGILLNTVFLVTEIRRNEQHDAFINAV
THELKTPVASIRLYLETLQTRPVDEAKRKEFYKIMLDDSDRLLSTIEQVLRTGRVGSTSHHLNRTRIDLDEVVRTSVERV
RLLHKVSADALCYQPCGPAAVMGDLDEVRAAVTNLVDNAVKYSGPEVHVVVETERVDRFVIVRVKDTGPGIPKTELKRVF
RRFYRVPGPLASRVKGTGLGLYIVRSVAKRHGGRAWAESEGPGLGSTFALQLPIAP

Sequences:

>Translated_296_residues
MDLSGRRKSVAGSIALAVGLISVLIVLYIGYVLLNWRTGILLMMGVLLVLMIICGILLNTVFLVTEIRRNEQHDAFINAV
THELKTPVASIRLYLETLQTRPVDEAKRKEFYKIMLDDSDRLLSTIEQVLRTGRVGSTSHHLNRTRIDLDEVVRTSVERV
RLLHKVSADALCYQPCGPAAVMGDLDEVRAAVTNLVDNAVKYSGPEVHVVVETERVDRFVIVRVKDTGPGIPKTELKRVF
RRFYRVPGPLASRVKGTGLGLYIVRSVAKRHGGRAWAESEGPGLGSTFALQLPIAP
>Mature_296_residues
MDLSGRRKSVAGSIALAVGLISVLIVLYIGYVLLNWRTGILLMMGVLLVLMIICGILLNTVFLVTEIRRNEQHDAFINAV
THELKTPVASIRLYLETLQTRPVDEAKRKEFYKIMLDDSDRLLSTIEQVLRTGRVGSTSHHLNRTRIDLDEVVRTSVERV
RLLHKVSADALCYQPCGPAAVMGDLDEVRAAVTNLVDNAVKYSGPEVHVVVETERVDRFVIVRVKDTGPGIPKTELKRVF
RRFYRVPGPLASRVKGTGLGLYIVRSVAKRHGGRAWAESEGPGLGSTFALQLPIAP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=30.5309734513274, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI145693157, Length=228, Percent_Identity=28.5087719298246, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87081816, Length=238, Percent_Identity=28.9915966386555, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790861, Length=210, Percent_Identity=32.8571428571429, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789403, Length=198, Percent_Identity=31.3131313131313, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788713, Length=225, Percent_Identity=23.5555555555556, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790551, Length=214, Percent_Identity=28.0373831775701, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790346, Length=211, Percent_Identity=26.5402843601896, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790436, Length=273, Percent_Identity=24.9084249084249, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=29.1304347826087, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788393, Length=238, Percent_Identity=24.3697478991597, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=29.1845493562232, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=223, Percent_Identity=27.8026905829596, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788549, Length=220, Percent_Identity=24.5454545454545, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786783, Length=220, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788279, Length=208, Percent_Identity=25.4807692307692, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790300, Length=238, Percent_Identity=26.0504201680672, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787894, Length=222, Percent_Identity=25.6756756756757, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 32815; Mature: 32815

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSGRRKSVAGSIALAVGLISVLIVLYIGYVLLNWRTGILLMMGVLLVLMIICGILLNT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFLVTEIRRNEQHDAFINAVTHELKTPVASIRLYLETLQTRPVDEAKRKEFYKIMLDDSD
HHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCH
RLLSTIEQVLRTGRVGSTSHHLNRTRIDLDEVVRTSVERVRLLHKVSADALCYQPCGPAA
HHHHHHHHHHHCCCCCCCHHHCCHHCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHH
VMGDLDEVRAAVTNLVDNAVKYSGPEVHVVVETERVDRFVIVRVKDTGPGIPKTELKRVF
HHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHH
RRFYRVPGPLASRVKGTGLGLYIVRSVAKRHGGRAWAESEGPGLGSTFALQLPIAP
HHHHCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MDLSGRRKSVAGSIALAVGLISVLIVLYIGYVLLNWRTGILLMMGVLLVLMIICGILLNT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFLVTEIRRNEQHDAFINAVTHELKTPVASIRLYLETLQTRPVDEAKRKEFYKIMLDDSD
HHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCH
RLLSTIEQVLRTGRVGSTSHHLNRTRIDLDEVVRTSVERVRLLHKVSADALCYQPCGPAA
HHHHHHHHHHHCCCCCCCHHHCCHHCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHH
VMGDLDEVRAAVTNLVDNAVKYSGPEVHVVVETERVDRFVIVRVKDTGPGIPKTELKRVF
HHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHH
RRFYRVPGPLASRVKGTGLGLYIVRSVAKRHGGRAWAESEGPGLGSTFALQLPIAP
HHHHCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]