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The map label for this gene is gatC [H]

Identifier: 116517184

GI number: 116517184

Start: 577874

End: 579349

Strand: Direct

Name: gatC [H]

Synonym: SPD_0561

Alternate gene names: 116517184

Gene position: 577874-579349 (Clockwise)

Preceding gene: 116516148

Following gene: 116515472

Centisome position: 28.24

GC content: 41.33

Gene sequence:

>1476_bases
ATGGATGCAATCTTTGACCTAATCGGAAAGGTTTTCAATCCCATCTTAGAAATGGGTGGACCTGTCATCATGTTGATCAT
TTTGACAGTATTGGCTTTACTTTTTGGAGTGAAATTCTCCAAAGCGCTTGAAGGTGGTATCAAACTTGCCATCGCTCTTA
CAGGTATCGGTGCTATCATCGGTATGCTAAATGGTGCTTTCTCAGCATCACTTGCAAAATTCGTTGAAAACACTGGTATC
CAATTGAGTATTACAGACGTTGGTTGGGCACCACTCGCAACAATCACTTGGGGTTCTGCTTGGACACTTTACTTCTTGCT
CATCATGTTGATTGTCAACGTAGTGATGCTTGCTATGAAGAAAACCGATACACTTGATGTCGATATCTTTGATATCTGGC
ACTTGTCTATCACAGGTCTCTTGATTAAATGGTATGCTGATAACAATGGTGTGAGTCAAGGGGTTTCACTCTTGATTGCT
ACAGCAGCTATCGTTCTTGTCGGTGTGTTGAAAATTATCAACTCTGACTTGATGAAACCTACATTTGATGACCTTCTTAA
CGCCCCAAGTTCATCACCAATGACATCAACTCACATGAACTACATGATGAACCCAGTTATCATGGTTTTGGATAAGATTT
TTGAAAAATTCTTCCCAGGCCTTGATAAATATGACTTTGATGCTGCTAAATTGAACAAGAAAATCGGTTTCTGGGGATCT
AAATTCTTCATCGGTTTCATCCTTGGTATCGTTATCGGTATTATGGGAACTCCACATCCAATTGCAGGTGTTGCAGATGC
AGATAAATGGCGTCTTGTTATCAAAGGATGGTTGTCTCTTGGTTTGACTGCCGGTGTATCTTTGGAACTCTTCTCACTTA
TCGGTTCATGGTTCATCGCAGCCGTAGAACCACTATCACAAGGTATTACAAACGTTGCTACTAAACGTCTTCAAGGACGT
AAATTCAATATCGGTCTTGACTGGCCATTCATCGCTGGTCGTGCTGAAATCTGGGCTTGTGCCAACGTACTTGCACCAAT
CATGTTGATTGAAGCAGTGCTTCTTTCAAAAGTTGGAAATGGTATCTTGCCACTTGCAGGTATCATCGCTATGGGTGTTA
CTCCAGCTCTCTTGGTTGTAACTCGTGGTAAATTGCTCCGTATGATTATCTTCGGAACACTCTTGTTGCCACTCTTCCTT
CTTTCAGGTACACTTATTGCACCATTTGCAACAGAACTTGCTAAAGGTGTAGGTGCCTTCCCAGAAGGTGTGAGCCAAAC
TCAATTGATTACTCACTCTACTCTTGAAGGACCAATCGAAAAACTTCTTGGTTGGACAATTGGTAACACTACAACTGGTG
ATATCAAAGCAATCCTTGGTGCAGTAGCCTTCCTTGTATTCTATATCGGTATCTTTGCTTGGTACAGAAAACAAATGATC
AAACGTAACGAAGAGTACGCAGCAAAAGCAAAATAA

Upstream 100 bases:

>100_bases
CTCCAGTATTTGACAATATTGAAGCAGCTATTAAAGAACATGGATTAAGCTAATTCTAATTTGTTAACATTCATATAACA
TAAAAAAGGGAGGAACTGTT

Downstream 100 bases:

>100_bases
TGCGCTCCTATAAAATATAAACTCAATGAAAATCAAAGAGCAAACTAGGAAGCTAGCCGCAGGTTGCTAAAAACACAGTT
TTGAGGTTGTAGATAAGACT

Product: PTS system, IIC component

Products: galactitol-1-phosphate [Cytoplasm]; pyruvate [C]

Alternate protein names: EIIC-Gat; PTS system galactitol-specific EIIC component [H]

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALEGGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGI
QLSITDVGWAPLATITWGSAWTLYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLLIA
TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFFPGLDKYDFDAAKLNKKIGFWGS
KFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKGWLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGR
KFNIGLDWPFIAGRAEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFGTLLLPLFL
LSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNTTTGDIKAILGAVAFLVFYIGIFAWYRKQMI
KRNEEYAAKAK

Sequences:

>Translated_491_residues
MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALEGGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGI
QLSITDVGWAPLATITWGSAWTLYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLLIA
TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFFPGLDKYDFDAAKLNKKIGFWGS
KFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKGWLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGR
KFNIGLDWPFIAGRAEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFGTLLLPLFL
LSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNTTTGDIKAILGAVAFLVFYIGIFAWYRKQMI
KRNEEYAAKAK
>Mature_491_residues
MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALEGGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGI
QLSITDVGWAPLATITWGSAWTLYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLLIA
TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFFPGLDKYDFDAAKLNKKIGFWGS
KFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKGWLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGR
KFNIGLDWPFIAGRAEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFGTLLLPLFL
LSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNTTTGDIKAILGAVAFLVFYIGIFAWYRKQMI
KRNEEYAAKAK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3775

COG function: function code G; Phosphotransferase system, galactitol-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788408, Length=426, Percent_Identity=27.2300469483568, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790758, Length=449, Percent_Identity=27.1714922048998, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013853
- InterPro:   IPR013014
- InterPro:   IPR004703 [H]

Pfam domain/function: PF03611 EIIC-GAT [H]

EC number: NA

Molecular weight: Translated: 52962; Mature: 52962

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALEGGIKLAIALTGIGAII
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEHHHHHHHHHH
GMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWTLYFLLIMLIVNVVMLAMK
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHEECCHHHHHHHHHHHHHHHHHHHHHH
KTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLLIATAAIVLVGVLKIINSDLMKP
CCCCCCEEHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFFPGLDKYDFDAAKLNKKIGFWGS
CHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHH
KFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKGWLSLGLTAGVSLELFSLIGSWFIA
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGRAEIWACANVLAPIMLIEAVLLSKVGN
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GILPLAGIIAMGVTPALLVVTRGKLLRMIIFGTLLLPLFLLSGTLIAPFATELAKGVGAF
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
PEGVSQTQLITHSTLEGPIEKLLGWTIGNTTTGDIKAILGAVAFLVFYIGIFAWYRKQMI
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRNEEYAAKAK
HCCHHHHCCCC
>Mature Secondary Structure
MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALEGGIKLAIALTGIGAII
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEHHHHHHHHHH
GMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWTLYFLLIMLIVNVVMLAMK
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHEECCHHHHHHHHHHHHHHHHHHHHHH
KTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLLIATAAIVLVGVLKIINSDLMKP
CCCCCCEEHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFFPGLDKYDFDAAKLNKKIGFWGS
CHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHH
KFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKGWLSLGLTAGVSLELFSLIGSWFIA
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGRAEIWACANVLAPIMLIEAVLLSKVGN
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GILPLAGIIAMGVTPALLVVTRGKLLRMIIFGTLLLPLFLLSGTLIAPFATELAKGVGAF
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
PEGVSQTQLITHSTLEGPIEKLLGWTIGNTTTGDIKAILGAVAFLVFYIGIFAWYRKQMI
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRNEEYAAKAK
HCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phosphoenolpyruvate; galactitol [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + galactitol [Periplasm] = galactitol-1-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]