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The map label for this gene is catE [H]

Identifier: 116517115

GI number: 116517115

Start: 73076

End: 73930

Strand: Direct

Name: catE [H]

Synonym: SPD_0072

Alternate gene names: 116517115

Gene position: 73076-73930 (Clockwise)

Preceding gene: 116517175

Following gene: 116515835

Centisome position: 3.57

GC content: 44.33

Gene sequence:

>855_bases
ATGACCTATGAATATAAGAGTCACATTTATTTGGCAGAGACAGCTTTAAATGTAAAGGATTTGGCCAGTCAAACAGCCTT
TTATCAGCAAGTTATTGGTTTAGAAATCTTATCTCAAACTGAGACAGAGTCCATTCTAGGCCTTGGTGGAAAAGTCTTGG
TACAGCTGATTCAAGCACAAGAGAGCGGAGAAGTGAGGGAACATTATGGTCTTTACCATTTGGCCATTCTCTTGCCCACA
CGCAAGGCTTTGGCTGATGTCTTGAAACACCTGACAGATTTGCAAATTCCTCTTGTCGGCGGTGCAGACCATGGTTACAG
TGAAGCTATTTACTTGGAAGATTTGGAGGGAAATGGCATTGAACTCTATCGAGATAAGCCAGTTTCCACATGGGATATTC
GAGAAGATGGACGCATTATCGGAGTGACGGAGGCTCTTGCGGCGCAGGACATTTATGAGTTGGGGGAAAGAGTAGAGCCC
TTTATCCTGGCAGAAGGTACAAGAATGGGGCATATTCATCTTTCCGTCAAGGATAGTCGAAAGTCCAGCCAGTTTTATCA
AAAGGTGTTAGGGCTAGAGGATAAATTCAGTGTGCCTAGCGCTAGTTGGATTGCGGCTGGAGATTACCATCATCATTTAG
CAGTTAACGAATGGAGAGGAAAAGGTCTGGCTTCGCGTAAGCAAGGCTTACCAGGTTTAGCCTACTATGTCATCGAAGTC
GCACATAAAAAAGAACTGTTAACGATTGCCCAACGAGCACAAGAAGTTGACGCACCAATCAAATGGATGACATCGAGCAA
ATTGGAAATCACAGACTCAGATGGCATCGTGACCCGTATTCGTTTAGCAAGGTAA

Upstream 100 bases:

>100_bases
TGAAATGGTGTTATTTTTGAGTTATCTGGCTTGACTTTCTTGATGGAAATTATATAATAGTTGTAATAATAATAATTACA
ACGAGAAAAGAGGACCATTT

Downstream 100 bases:

>100_bases
AATTAGGAATTTTTAATAAGTTATAAGTATTGCTAGTTTGCTTTTTGAACGGTCTTTGGTAACAGAACTGCGTGAGCTGG
ATGGGTGAGAATTTTGACAA

Product: hypothetical protein

Products: NA

Alternate protein names: Catechol-induced ring cleavage extradiol dioxygenase [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETESILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPT
RKALADVLKHLTDLQIPLVGGADHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEWRGKGLASRKQGLPGLAYYVIEV
AHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGIVTRIRLAR

Sequences:

>Translated_284_residues
MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETESILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPT
RKALADVLKHLTDLQIPLVGGADHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEWRGKGLASRKQGLPGLAYYVIEV
AHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGIVTRIRLAR
>Mature_283_residues
TYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETESILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTR
KALADVLKHLTDLQIPLVGGADHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEPF
ILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEWRGKGLASRKQGLPGLAYYVIEVA
HKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGIVTRIRLAR

Specific function: Involved in the meta cleavage of catechol to 2- hydroxymuconic semialdehyde. Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol [H]

COG id: COG2514

COG function: function code R; Predicted ring-cleavage extradiol dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the extradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR000486 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: =1.13.11.2 [H]

Molecular weight: Translated: 31724; Mature: 31592

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00934 GLYOXALASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETESILGLGGKVLVQLIQAQ
CCEEECCEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHH
ESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGADHGYSEAIYLEDLEGNGI
CCCCHHHHHCEEEEEEEECCHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEECCCCCE
ELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEPFILAEGTRMGHIHLSVKDSR
EEEECCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEEEEECCC
KSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEWRGKGLASRKQGLPGLAYYVIEV
HHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCHHHCCCCHHHHHHHHH
AHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGIVTRIRLAR
HHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCCEEEEEEECC
>Mature Secondary Structure 
TYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETESILGLGGKVLVQLIQAQ
CEEECCEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHH
ESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGADHGYSEAIYLEDLEGNGI
CCCCHHHHHCEEEEEEEECCHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEECCCCCE
ELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEPFILAEGTRMGHIHLSVKDSR
EEEECCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEEEEECCC
KSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEWRGKGLASRKQGLPGLAYYVIEV
HHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCHHHCCCCHHHHHHHHH
AHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGIVTRIRLAR
HHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377 [H]