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The map label for this gene is yajL [H]

Identifier: 116516953

GI number: 116516953

Start: 722132

End: 722686

Strand: Direct

Name: yajL [H]

Synonym: SPD_0707

Alternate gene names: 116516953

Gene position: 722132-722686 (Clockwise)

Preceding gene: 116515576

Following gene: 116515873

Centisome position: 35.29

GC content: 43.6

Gene sequence:

>555_bases
ATGGTAAAAGTAGCAGTTATGTTAGCTCAGGGCTTTGAAGAAATTGAAGCCTTGACAGTTGTAGATGTCTTGCGTCGAGC
CAATATCACATGTGATATGGTTGGTTTTGAAGAGCAAGTAACGGGTTCGCATGCAATCCAAGTAAGAGCAGATCATGTCT
TTGATGGAGATTTATCAGACTATGATATGATTGTTCTTCCTGGAGGTATGCCTGGTTCTGCACATTTACGTGATAATCAG
ACCTTGATTCAAGAATTGCAAAGCTTCGAGCAAGAAGGGAAGAAACTAGCAGCCATTTGTGCGGCACCAATTGCCCTCAA
TCAAGCAGAGATATTGAAAAATAAGCGATACACTTGTTATGACGGCGTTCAAGAGCAAATCCTTGATGGTCACTACGTCA
AGGAAACAGTAGTGGTAGATGGTCAGTTGACAACCAGTCGGGGTCCTTCAACAGCCCTTGCCTTTGCCTACGAGTTGGTG
GAGCAACTAGGAGGGGACGCAGAGAGTTTACGAACAGGAATGCTCTATCGAGATGTCTTTGGTAAAAATCAGTAA

Upstream 100 bases:

>100_bases
TCGATGAGTTACCAGACTAATCTAGCTGAAGAAAAGAGCGGAAAAGTCCCATTCAAACGGAAAAAGGTTGTATTAAAACA
AATTAAATAAGGAGAAAATC

Downstream 100 bases:

>100_bases
AACGGGAGTTATTCTCTCGTTTTTTATGTGGAAAACTCAGGGAAATCATCGCTTTTTTCATAAAAAAATGCTATAATGAA
GGGTATGAAATATCACGATT

Product: 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSHAIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQ
TLIQELQSFEQEGKKLAAICAAPIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
EQLGGDAESLRTGMLYRDVFGKNQ

Sequences:

>Translated_184_residues
MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSHAIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQ
TLIQELQSFEQEGKKLAAICAAPIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
EQLGGDAESLRTGMLYRDVFGKNQ
>Mature_184_residues
MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSHAIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQ
TLIQELQSFEQEGKKLAAICAAPIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
EQLGGDAESLRTGMLYRDVFGKNQ

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=188, Percent_Identity=35.6382978723404, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI31543380, Length=188, Percent_Identity=35.6382978723404, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI87081736, Length=171, Percent_Identity=33.9181286549708, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17531319, Length=179, Percent_Identity=35.7541899441341, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17558714, Length=161, Percent_Identity=31.055900621118, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571932, Length=165, Percent_Identity=40, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24653499, Length=179, Percent_Identity=36.3128491620112, Blast_Score=98, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 20182; Mature: 20182

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSHAIQVRADHVFDGDLSD
CEEEEEHHHHCHHHHHHHHHHHHHHHCCCEEEEECCHHHCCCCEEEEEEECEEECCCCCC
YDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAAPIALNQAEILKNKRYTCY
CCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHCCCCCHH
DGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELVEQLGGDAESLRTGMLYRDVF
HHHHHHHHCCCEEEEEEEECCEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GKNQ
CCCC
>Mature Secondary Structure
MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSHAIQVRADHVFDGDLSD
CEEEEEHHHHCHHHHHHHHHHHHHHHCCCEEEEECCHHHCCCCEEEEEEECEEECCCCCC
YDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAAPIALNQAEILKNKRYTCY
CCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHCCCCCHH
DGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELVEQLGGDAESLRTGMLYRDVF
HHHHHHHHCCCEEEEEEEECCEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GKNQ
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]