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The map label for this gene is yfhA [H]

Identifier: 116516717

GI number: 116516717

Start: 929792

End: 930799

Strand: Direct

Name: yfhA [H]

Synonym: SPD_0917

Alternate gene names: 116516717

Gene position: 929792-930799 (Clockwise)

Preceding gene: 116516465

Following gene: 116515486

Centisome position: 45.44

GC content: 30.36

Gene sequence:

>1008_bases
ATGCAAAATTTAATTATAGGTATTCAAAAAAGAAAAAATAGAATAACACTATTTTCCTCACTATTTTTATTAATAATAAT
CAGTCTATCATTTTTCATTTTACTTATCGGAGATGAAAGTTATTCTTTTTCAACTTTGATTAAAGTCTTAAATAGTGAAA
CTGTTCCTGGAGCTAGTTTTTCGATTATGGAAATTAGATTACCAAAATTATTAGCAGGAATTATAGCTGGCTGGTCTTTT
GGATTGGCAGGATTTATCTTTCAAACTATGTTAAGAAATCCTCTTGCAAGTCCTGATATAATCGGTGTCACAAGTTCTTC
ATCTATTGCAGCGGTCTTTTGCATATTGGTATTAAAAACAAATAGTTTAACTACTGGAATTATTTCAATAACTTGTGGAC
TAACATCATCTTTAATATTATTTTTACTAGCTAAAAAAGATGGTTTTTCAGCAGCAAGACTGATAATATTAGGTATTGGT
TTTCAAGCTGTCACAAGAGCAGGCACCTCATTTTTATTGTTGAAAGTAGCAAGATATGAATTACAAGAAGTTATGAGATG
GCTCAGTGGCTCTTTATCTTTTACAAAGTTAGATGACATACCTCTTGTTCTAATAGTAAGTATTATTGCTACTATATTAG
TTTTATTTTTTAATAAAAGACTAGAAATTATTGAACTTGGTGAAGAAATAGCAATCGGACTTGGAGCAAATCCCGAGCTT
TCAAGGCTTGTTTTAATTTTTTGCGCTGTATCTTTAACTGCTTTTTCTACTTCAATTACAGGACCAATAGCTTGTATATC
TTTTTTAGCTGGTCCCATAGCCTTAAATATTGGCAAGAAAAGAAGCCCAATATTAGCTGGATTGGTTGGAATTTTACTAG
TTTTGTTATCAGACATATTCTCTCAAAATATTTTACCAGCTAGATATCCAGTAGGTGTTGTAACTGGCTTGTTAGGTTCA
CCATACTTAATATACTTACTAATAAAAATGAACAGGAGAAATATATAA

Upstream 100 bases:

>100_bases
TAGGTAAACCAGGTGAAATTGAAGTGGGGATAATTACTGCAATAATCGGGGGTCCAGTACTTATTTATGTAACTATGAAA
AATAGAGGGGTTAATAACTA

Downstream 100 bases:

>100_bases
TGAAAGGTCTGTGGTCAAATAATCTTACCTGCGGTTATGATGAAAAAATAATCTTGGAAAATATAAATATAAAAATACCT
GAAGAAAAAATATCAGTTAT

Product: iron-compound ABC transporter permease

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFSTLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSF
GLAGFIFQTMLRNPLASPDIIGVTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFNKRLEIIELGEEIAIGLGANPEL
SRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGS
PYLIYLLIKMNRRNI

Sequences:

>Translated_335_residues
MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFSTLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSF
GLAGFIFQTMLRNPLASPDIIGVTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFNKRLEIIELGEEIAIGLGANPEL
SRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGS
PYLIYLLIKMNRRNI
>Mature_335_residues
MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFSTLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSF
GLAGFIFQTMLRNPLASPDIIGVTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFNKRLEIIELGEEIAIGLGANPEL
SRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGS
PYLIYLLIKMNRRNI

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=281, Percent_Identity=35.5871886120996, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790740, Length=283, Percent_Identity=30.7420494699647, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1786347, Length=319, Percent_Identity=26.9592476489028, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786805, Length=306, Percent_Identity=30.0653594771242, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788004, Length=286, Percent_Identity=26.2237762237762, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1790741, Length=293, Percent_Identity=27.6450511945392, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36155; Mature: 36155

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFSTLIKVLNSETVPGASF
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHCCCCCCCCCE
SIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIGVTSSSSIAAVFCILVLKT
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCC
NSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIGFQAVTRAGTSFLLLKVARYE
CCCCEEHEEEEHHHHHHHHHHHHHCCCCCCHHHHHHEECCHHHHHHCCHHHHHHHHHHHH
LQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFNKRLEIIELGEEIAIGLGANPEL
HHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCHHEEECCCHHEEECCCCCHH
SRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHH
SQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRNI
HCCCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCC
>Mature Secondary Structure
MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFSTLIKVLNSETVPGASF
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHCCCCCCCCCE
SIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIGVTSSSSIAAVFCILVLKT
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCC
NSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIGFQAVTRAGTSFLLLKVARYE
CCCCEEHEEEEHHHHHHHHHHHHHCCCCCCHHHHHHEECCHHHHHHCCHHHHHHHHHHHH
LQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFNKRLEIIELGEEIAIGLGANPEL
HHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCHHEEECCCHHEEECCCCCHH
SRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHH
SQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRNI
HCCCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]