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The map label for this gene is prmA

Identifier: 116516647

GI number: 116516647

Start: 1591511

End: 1592461

Strand: Reverse

Name: prmA

Synonym: SPD_1573

Alternate gene names: 116516647

Gene position: 1592461-1591511 (Counterclockwise)

Preceding gene: 116515601

Following gene: 116515693

Centisome position: 77.83

GC content: 48.37

Gene sequence:

>951_bases
ATGGAAACATGGCAAGAGTTAAAAGTTACAGTGAAGCGTGAGGGAGAGGAGTTGGTTTCCAATCTCTTGATTGAGCTGGG
AGCGCAAGGAGTCGCGATTGAAGACAGCATGGACTATATGGGAAATGTGGATCGTTTTGGCGAGATTTTCCCAGAGGTGG
AGCAGCAAGAAGAAATCGTAGTGACAGCCTACTACCCTGACACGGTGGATGTGACAGTGGTTGAGGCGGACTTGCAGGCT
CGCTTAGCAGAATTGACGGATTTTATGGATTTGGGTGAAGTCAAGATGGGGACGACTGCCTTGGCTGAGGAAGACTGGGC
AGACAACTGGAAGAAATACTATGAGCCAGCTCGTATCACTCATGATTTGACCATCGTTCCCTCTTGGACAGACTATGAGG
CGACTGCGGGAGAAAAAATTATCAAGCTAGATCCTGGGATGGCTTTTGGTACTGGGACCCATCCAACTACCAAGATGAGC
CTCTTTGCCTTGGAACAGGTTCTTCGTGGTGGCGAGACAGTGCTAGATGTGGGGACTGGTTCAGGGGTTCTCTCCATTGC
TAGCTCGCTACTTGGTGCCAAGGAAATCTTCGCCTATGACCTGGATGATGTGGCGGTTCGTGTTGCTCAGGAAAATATTG
AACTTAACCCTGGAATGGAAAATATCCACGTTGCTGCTGGAGACTTGCTTAAGGGTGTTGAGATTGAGGCAGATGTGATT
GTAGCTAATATCTTGGCGGATATTCTCATTCATCTGACAGACGATGCCTATCGTTTGGTCAAGGATGAAGGCTACCTGAT
CATGAGTGGCATTATCAAGGACAAGTGGGACATGGTGCGCGAGTCGGCTGAGTCAGCTGGATTTTTCCTTGAAACCCACA
TGGTTCAAGGGGAATGGAATGCCTGTGTCTTTAAGAAAACCAAGGATATTTCTGGTGTGATTGGAGGCTAG

Upstream 100 bases:

>100_bases
CCTAAACACTGTGCCAAAAAGATAAACTTCTCTTAGACACAAGCGTCTTCAGAGAATTTCCTATTTTGGTTTTGTGTTTT
ACGGGCTTGGTATCTTAATA

Downstream 100 bases:

>100_bases
CATGCAGCAGTATTTTGTAAAAGGCAGTGCTATCTCTCCTGTCACTATCGAGGACAAGGAAACCAGTAAGCATATGTTTC
AGGTTATGCGCTTGAAAGAA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVDRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQA
RLAELTDFMDLGEVKMGTTALAEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPGMENIHVAAGDLLKGVEIEADVI
VANILADILIHLTDDAYRLVKDEGYLIMSGIIKDKWDMVRESAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG

Sequences:

>Translated_316_residues
METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVDRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQA
RLAELTDFMDLGEVKMGTTALAEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPGMENIHVAAGDLLKGVEIEADVI
VANILADILIHLTDDAYRLVKDEGYLIMSGIIKDKWDMVRESAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG
>Mature_316_residues
METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVDRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQA
RLAELTDFMDLGEVKMGTTALAEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPGMENIHVAAGDLLKGVEIEADVI
VANILADILIHLTDDAYRLVKDEGYLIMSGIIKDKWDMVRESAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=261, Percent_Identity=29.8850574712644, Blast_Score=101, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_STRP2 (Q04J12)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_817026.1
- ProteinModelPortal:   Q04J12
- SMR:   Q04J12
- STRING:   Q04J12
- EnsemblBacteria:   EBSTRT00000019040
- GeneID:   4443051
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1573
- eggNOG:   COG2264
- GeneTree:   EBGT00050000028027
- HOGENOM:   HBG584653
- OMA:   IELNPGM
- ProtClustDB:   PRK00517
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34776; Mature: 34776

Theoretical pI: Translated: 4.00; Mature: 4.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVDRFGEIFPEVEQQEEIV
CCCHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCHHHHCCHHHHHHHCCCCCCCCCEE
VTAYYPDTVDVTVVEADLQARLAELTDFMDLGEVKMGTTALAEEDWADNWKKYYEPARIT
EEEECCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHCCCCCEE
HDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMSLFALEQVLRGGETVLDVGTG
EEEEEECCCCCCCCCCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCC
SGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPGMENIHVAAGDLLKGVEIEADVI
CCHHHHHHHHHCHHHHHEECHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHCCCEEEHHHH
VANILADILIHLTDDAYRLVKDEGYLIMSGIIKDKWDMVRESAESAGFFLETHMVQGEWN
HHHHHHHHHHHHCCCHHHHHHCCCEEEEECHHHHHHHHHHHHHHHCCEEEEEEEECCCCC
ACVFKKTKDISGVIGG
EEEEEECCCCCCCCCC
>Mature Secondary Structure
METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVDRFGEIFPEVEQQEEIV
CCCHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCHHHHCCHHHHHHHCCCCCCCCCEE
VTAYYPDTVDVTVVEADLQARLAELTDFMDLGEVKMGTTALAEEDWADNWKKYYEPARIT
EEEECCCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHCCCCCEE
HDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMSLFALEQVLRGGETVLDVGTG
EEEEEECCCCCCCCCCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCC
SGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPGMENIHVAAGDLLKGVEIEADVI
CCHHHHHHHHHCHHHHHEECHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHCCCEEEHHHH
VANILADILIHLTDDAYRLVKDEGYLIMSGIIKDKWDMVRESAESAGFFLETHMVQGEWN
HHHHHHHHHHHHCCCHHHHHHCCCEEEEECHHHHHHHHHHHHHHHCCEEEEEEEECCCCC
ACVFKKTKDISGVIGG
EEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA