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The map label for this gene is iga

Identifier: 116516343

GI number: 116516343

Start: 1037492

End: 1043383

Strand: Direct

Name: iga

Synonym: SPD_1018

Alternate gene names: 116516343

Gene position: 1037492-1043383 (Clockwise)

Preceding gene: 116517013

Following gene: 116515446

Centisome position: 50.71

GC content: 39.09

Gene sequence:

>5892_bases
ATGGAAAAGTATTTTGGTGAAAAACAAGAGCGTTTTTCATTTAGAAAATTATCAGTAGGACTTGTATCTGCAACGATTTC
AAGTTTATTTTTTATGTCTGTATTAGCTAGTTCATCTGTGGATGCTCAAGAAACTGCGGGAGTTCACTATAAATATGTGG
CAGATTCAGAGCTATCATCAGAAGAAAAGAAGCAGCTTGTCTATGATATTCCGACATACGTGGAGAATGATGATGAAACT
TATTATCTTGTTTATAAGTTAAATTCTCAAAATCAACTGGCGGAATTACCAAATACTGGAAGCAAGAATGAGAGGCAAGC
CCTAGTTGCTGGTGCTAGCTTAGCTGCTCTGGGAATTTTAATTTTTGCTGTTTCCAAGAAAAAGGTTAAGAATAAAACGG
TATTACATTTAGTATTGGTTGCGGGAATGGGAAATGGTGTCTTAGTTTCAGTCCATGCTTTAGAAAATCATCTTTTGCTA
AATTACAATACGGACTATGAATTGACCTCTGGAGAAAAATTACCTCTTCCTAAAGAGATTTCAGGTTACACTTATATTGG
ATATATCAAAGAGGGAAAAACGACTTCTGATTTTGAAGTAAGTAATCAAGAAAAATCAGCAGCCACTCCTACAAAACAAC
AAAAGGTGGATTATAATGTTACACCAAATTTTGTAGACCATCCATCAACAGTACAAGCTATTCAGGAACAAACACCTGTT
TCTTCAACTAAGCCGACAGAAGTTCAAGTAGTTGAAAAACCTTTCTCTACTGAATTAATCAATCCAAGAAAAGAAGAGAA
ACAATCTTCAGATTCTCAAGAACAATTAGCCGAACATAAGAATCTAGAAACGAAGAAAGAGGAGAAGATTTCTCCAAAAG
AAAAGACTGGGGTAAATACATTAAATCCACAGGATGAAGTTTTATCAGGTCAATTGAACAAACCTGAACTCTTATATCGT
GAGGAAACTATAGAGACAAAAATAGATTTTCAAGAAGAAATTCAAGAAAATCCTGATTTAGCTGAAGGAACTGTAAGAGT
AAAACAAGAAGGTAAATTAGGTAAGAAAGTTGAAATCGTCAGAATATTCTCTGTAAACAAGGAAGAAGTTTCGCGAGAAA
TTGTTTCAACTTCAACGACTGCGCCTAGTCCAAGAATAGTCGAAAAAGGTACTAAAAAAACTCAAGTTATAAAGGAACAA
CCTGAGACTGGTGTAGAACATAAGGACGTACAGTCTGGAGCTATTGTTGAACCCGCAATTCAGCCTGAGTTGCCCGAAGC
TGTAGTAAGTGATAAAGGCGAACCAGAAGTTCAACCGACATTACCCGAAGCAGTTGTGACCGACAAAGGTGAGACTGAGG
TTCAACCAGAGTCGCCAGATACTGTGGTAAGTGATAAAGGTGAACCAGAGCAGGTAGCCCCATTGCCAGAATATAAGGGT
AATATTGAGCAAGTAAAACCTGAAACTCCGGTTGAGAAGACCAAAGAACAAGGTCCAGAAAAAACTGAAGAAGTTCCAGT
AAAACCAACAGAAGAAACACCAGTAAATCCAAATGAAGGTACTACAGAAGGAACCTCAATTCAAGAAGCAGAAAATCCAG
TTCAACCTGCAGAAGAATCAACAACGAATTCAGAGAAAGTATCACCAGATACATCTAGCGAAAATACTGGGGAAGTGTCC
AGTAATCCTAGTGATTCGACAACCTCAGTTGGAGAATCAAATAAACCAGAACATAATGACTCTAAAAATGAAAATTCAGA
AAAAACTGTAGAAGAAGTTCCAGTAAATCCAAATGAAGGCACAGTAGAAGGTACCTCAAATCAAGAAACAGAAAAACCAG
TTCAACCTGCAGAAGAAACACAAACAAACTCTGGGAAAATAGCTAACGAAAATACTGGAGAAGTATCCAATAAACCTAGT
GATTCAAAACCACCAGTTGAAGAATCAAATCAACCAGAAAAAAACGGAACTGCAACAAAACCAGAAAATTCAGGTAATAC
AACATCAGAGAATGGACAAACAGAACCAGAGAAAAAACTCGAATTAAGAAATGTTTCTGATATTGAGTTGTATAGTCAGA
CGAATGGAACCTACAGACAACATGTTTCATTGGATGGAATTCCAGAGAATACGGATACTTACTTTGTCAAGGTAAAATCT
TCAGCATTTAAAGATGTCTATATACCAGTAGCTTCAATAACCGAAGAGAAAAGAAATGGGCAGTCAGTTTATAAAATCAC
AGCCAAAGCTGAGAAACTCCAGCAAGAACTAGAAAATAAATATGTCGACAATTTCACCTTCTACCTCGATAAGAAGGCTA
AAGAGGAAAATACAAACTTTACTTCCTTTAGCAACCTGGTCAAAGCTATAAACCAAAATCCCTCTGGAACCTATCATTTA
GCGGCCAGCCTGAATGCTAACGAAGTGGAGCTTGGTCCTGATGAAAGATCCTATATCAAGGACACCTTTACTGGTCGTTT
AATCGGTGAAAAAGATGGCAAGAATTATGCTATCTATAATTTGAAAAAACCTCTGTTTGAAAACTTGAGTGGTGCTACAG
TAGAAAAACTGAGTCTAAAAAATGTTGCTATTTCAGGGAAAAATGATATTGGTTCACTGGCAAATGAAGCTACGAATGGC
ACAAAGATTAAACAAGTTCATGTTGATGGTGTTCTGGCTGGAGAACGTGGTGTCGGTGGTTTGTTGGCTAAGGCAGACCA
ATCAAGCATCGCAGAGAGCAGTTTCAAGGGAAGAATTGTCAATACCTATGAAACGACTGATGCCTACAATATTGGCGGTC
TGGTCGGTCATTTAACAGGAAAAAATGCGTCTATTGCTAAATCCAAAGCGACAGTAACCATTTCGTCAAACACCAATAGG
TCAGATCAGACTGTCGGTGGTCTTGCAGGTCTAGTAGACCAAGATGCGCATATACAGAACAGTTATGCGGAAGGTGATAT
TAATAATGTCAAGCACTTTGGTAAAGTCGCTGGTGTGGCAGGATATTTGTGGGATCGAACTTCTGGTGAGGAAAAACACG
CTGGTGAATTGACCAATGTTCTTAGCGATGTCAATGTAACAAACGGAAATGCCATCACTGGATACCACTATACAGGAATG
AAGGTAGCTAATACATTTAGTAGTAAGGCTAATAGAGTTTTCAATGTCACTTTAGAGAAGGATGAGGTCGTCAGCAAGGA
ATCCTTTGAAGAAAGAGGAACAATGCTAGATGCTTCTCAAATTGTAAGCAAAAAAGCAGAAATAAATCCTCTCACTCTAC
CAACGGTGGAACCCCTCTCAACAAGTGGCAAGAAAGACAGTGATTTTTCTAAGATAGCCCATTATCAAGCTAACCGTGCT
TTGGTTTATAAGAACATTGAAAAATTGTTACCTTTTTATAATAAGTCAACCATCGTCAAATACGGAAACCTGGTTAAGGA
GAACAGTCTCTTATACCAAAAAGAACTCTTATCTGCAGTTATGATGAAGGATGACCAAGTAATCACAGATATTGTTTCCA
ACAAACAGACTGCAAACAAACTCTTACTTCACTATAATGACCATTCATCTGAGAAATTTGATCTCAAGTACCAGACTGAT
TTTGCCAATCTAGCAGAATATAATCTAGGTAATACGGGACTTCTCTACACTCCTAACCAATTCTTATATGATCGAGACTC
TATTGTTAAGGAAGTCTTGCCTGAGTTGCAGAAGCTTGATTACCAGTCAGATGCTATCAGAAAGACACTTGGTATTTCTC
CAGAAGTTAAGTTAACCGAGCTCTATTTAGAAGACCAGTTCTCCAAAACAAAACAAAATCTGGGAGACAGCTTGAAAAAA
CTTTTGTCAGCAGATGCCGGTCTAGCTAGCGATAACTCAGTCACCAGAGGCTATCTTGTAGATAAAATCAAGAATAATAA
GGAAGCCTTGCTACTCGGTTTAACTTATTTAGAACGTTGGTATAACTTTAACTATGGTCAAGTGAATGTCAAAGACCTAG
TTATGTATCATCCAGACTTCTTTGGTAAAGGAAATACTTCCCCACTAGATACTCTGATTGAGTTAGGTAAATCTGGCTTT
AACAATCTTCTAGCTAAGAATAATGTCGATACTTATGGTATCAGTCTTGCCAGTCAACATGGAGCGACAGATTTGTTTAG
CACGCTGGAACATTACCGAAAAGTCTTTTTACCAAATACAAGCAATAATGACTGGTTTAAATCAGAGACTAAGGCTTACA
TTGTCGAAGAAAAATCCACTATCGAAGAGGTGAAAACGAAGCAAGGGTTAGCTGGCACCAAGTATTCTATCGGTGTTTAT
GATCGTATCACGAGTGCCACATGGAAATACCGCAATATGGTCTTGCCTCTCCTGACCTTGCCAGAGAGATCCGTATTTGT
CATCTCGACCATGTCTAGTCTAGGATTTGGAGCTTATGATCGCTACCGCAGTAGTGACCATAAAGCGGGCAAGGCTCTCA
ATGATTTTGTTGAAGAAAATGCGCGTGAAACAGCCAAACGTCAGCGAGATCACTACGATTATTGGTATCGTATTTTAGAT
GAACAGTCACGCGAAAAACTCTATCGTACGATTCTCCTTTATGATGCCTATAAGTTTGGGGATGACACAACATCAGGAAA
AGCTACAGCGGAGGCTAAGTTTGATAGCTCCAATCCAGCTATGAAGAACTTCTTTGGACCAGTTGGCAATAAGGTAGTAC
ACAACCAGCATGGAGCCTACGCTACAGGGGACGGCGTCTACTATATGTCTTACCGCATGCTGGACAAGGATGGAGCCATT
ACTTATACCCATGAAATGACCCATGATTCGGATCAGGATATTTACCTTGGTGGCTATGGTCGAAGAAATGGCTTGGGACC
AGAGTTCTTCGCAAAAGGCTTATTGCAAGCCCCTGACCAACCAAGTGACGCAACCATTACCATTAATTCTATCTTGAAAC
ACTCAAAATCAGATAGTACAGAGGGATCCCGTCTTCAAGTCTTGGATCCGACAGAGAGATTCCAAAACGCAGCAGATCTT
CAGAACTATGTCCATAACATGTTTGACCTTATCTACATGATGGAATATCTCGAAGGGCAGTCAATCGTTAATAAACTAAG
TGTTTACCAGAAAATGGCGGCTCTCAGAAAAATTGAGAACAAGTATGTGAAAGATCCAGCAGATGGAAATGAGGTTTATG
CCACTAACGTAGTCAAAGAATTGACAGAAGCAGAGGCCCGAAACCTGAATAGTTTTGAAAGTTTGATTGACCACAACATC
TTATCAGCTCGTGAGTACCAGTCTGGCGACTATGAACGAAATGGCTACTATACCATCAAACTCTTTGCCCCAATCTATTC
AGCTCTCAGCAGTGAGAAAGGCACACCAGGGGACCTTATGGGACGTAGGATTGCGTACGAACTTTTGGCTGCCAAAGGCT
TTAAGGATGGAATGGTACCTTATATCTCAAACCAATACGAAGAAGATGCTAAACAACAAGGGCAAACTATCAATCTTTAT
GGTAAAGAACGGGGCTTGGTGACCGATGAGCTTGTTTTGAAAAAGGTATTTGACGGTAAGTATAAAACTTGGGCAGAATT
TAAGACAGCTATGTACCAAGAACGGGTGGATCAGTTTGGAAACTTGAAGCAGGTGACCTTTAAAGATCCGACAAAACCAT
GGCCAAGCTATGGCACAAAGACTATCAATAATGTGGATGAATTGCAAGCCCTCATGGACCAAGCTGTTCTCAAGGATGCT
GAAGGTCCACGTTGGAGTAATTATGATCCAGAAATCGACAGTGCCGTTCATAAGTTGAAGAGAGCAATCTTTAAAGCCTA
TCTTGACCAAACAAATGATTTTAGAAGTTCAATTTTTGAGAATAAAAAATAG

Upstream 100 bases:

>100_bases
GTATAATTAAGGTATACTGCCTTTTCTATAGATAATAGATAATACACTAATATAATAAAGGTCTTTGTAACATATATAAA
TTTTATTTCAAGGAGGAATA

Downstream 100 bases:

>100_bases
TGTTTACTATTAGGAAATAAAGTTTAAAAAGGTGATGAAGAACAAACCAAGATTCAAGCAGGAATTCCTACTGATAATGA
AGTAAGTTATGCTCTTATTT

Product: immunoglobulin A1 protease precursor

Products: NA

Alternate protein names: IgA1 protease; IgA-specific zinc metalloproteinase

Number of amino acids: Translated: 1963; Mature: 1963

Protein sequence:

>1963_residues
MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDET
YYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPV
SSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYR
EETIETKIDFQEEIQENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTKKTQVIKEQ
PETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKGETEVQPESPDTVVSDKGEPEQVAPLPEYKG
NIEQVKPETPVEKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVS
SNPSDSTTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNSGKIANENTGEVSNKPS
DSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLELRNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKS
SAFKDVYIPVASITEEKRNGQSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTYHL
AASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEKLSLKNVAISGKNDIGSLANEATNG
TKIKQVHVDGVLAGERGVGGLLAKADQSSIAESSFKGRIVNTYETTDAYNIGGLVGHLTGKNASIAKSKATVTISSNTNR
SDQTVGGLAGLVDQDAHIQNSYAEGDINNVKHFGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGNAITGYHYTGM
KVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEINPLTLPTVEPLSTSGKKDSDFSKIAHYQANRA
LVYKNIEKLLPFYNKSTIVKYGNLVKENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTD
FANLAEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELYLEDQFSKTKQNLGDSLKK
LLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERWYNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGF
NNLLAKNNVDTYGISLASQHGATDLFSTLEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYSIGVY
DRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALNDFVEENARETAKRQRDHYDYWYRILD
EQSREKLYRTILLYDAYKFGDDTTSGKATAEAKFDSSNPAMKNFFGPVGNKVVHNQHGAYATGDGVYYMSYRMLDKDGAI
TYTHEMTHDSDQDIYLGGYGRRNGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVLDPTERFQNAADL
QNYVHNMFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDPADGNEVYATNVVKELTEAEARNLNSFESLIDHNI
LSAREYQSGDYERNGYYTIKLFAPIYSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLY
GKERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTKTINNVDELQALMDQAVLKDA
EGPRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK

Sequences:

>Translated_1963_residues
MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDET
YYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPV
SSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYR
EETIETKIDFQEEIQENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTKKTQVIKEQ
PETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKGETEVQPESPDTVVSDKGEPEQVAPLPEYKG
NIEQVKPETPVEKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVS
SNPSDSTTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNSGKIANENTGEVSNKPS
DSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLELRNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKS
SAFKDVYIPVASITEEKRNGQSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTYHL
AASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEKLSLKNVAISGKNDIGSLANEATNG
TKIKQVHVDGVLAGERGVGGLLAKADQSSIAESSFKGRIVNTYETTDAYNIGGLVGHLTGKNASIAKSKATVTISSNTNR
SDQTVGGLAGLVDQDAHIQNSYAEGDINNVKHFGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGNAITGYHYTGM
KVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEINPLTLPTVEPLSTSGKKDSDFSKIAHYQANRA
LVYKNIEKLLPFYNKSTIVKYGNLVKENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTD
FANLAEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELYLEDQFSKTKQNLGDSLKK
LLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERWYNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGF
NNLLAKNNVDTYGISLASQHGATDLFSTLEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYSIGVY
DRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALNDFVEENARETAKRQRDHYDYWYRILD
EQSREKLYRTILLYDAYKFGDDTTSGKATAEAKFDSSNPAMKNFFGPVGNKVVHNQHGAYATGDGVYYMSYRMLDKDGAI
TYTHEMTHDSDQDIYLGGYGRRNGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVLDPTERFQNAADL
QNYVHNMFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDPADGNEVYATNVVKELTEAEARNLNSFESLIDHNI
LSAREYQSGDYERNGYYTIKLFAPIYSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLY
GKERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTKTINNVDELQALMDQAVLKDA
EGPRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK
>Mature_1963_residues
MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDET
YYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPV
SSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYR
EETIETKIDFQEEIQENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTKKTQVIKEQ
PETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKGETEVQPESPDTVVSDKGEPEQVAPLPEYKG
NIEQVKPETPVEKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVS
SNPSDSTTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNSGKIANENTGEVSNKPS
DSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLELRNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKS
SAFKDVYIPVASITEEKRNGQSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTYHL
AASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEKLSLKNVAISGKNDIGSLANEATNG
TKIKQVHVDGVLAGERGVGGLLAKADQSSIAESSFKGRIVNTYETTDAYNIGGLVGHLTGKNASIAKSKATVTISSNTNR
SDQTVGGLAGLVDQDAHIQNSYAEGDINNVKHFGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGNAITGYHYTGM
KVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEINPLTLPTVEPLSTSGKKDSDFSKIAHYQANRA
LVYKNIEKLLPFYNKSTIVKYGNLVKENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTD
FANLAEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELYLEDQFSKTKQNLGDSLKK
LLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERWYNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGF
NNLLAKNNVDTYGISLASQHGATDLFSTLEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYSIGVY
DRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALNDFVEENARETAKRQRDHYDYWYRILD
EQSREKLYRTILLYDAYKFGDDTTSGKATAEAKFDSSNPAMKNFFGPVGNKVVHNQHGAYATGDGVYYMSYRMLDKDGAI
TYTHEMTHDSDQDIYLGGYGRRNGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVLDPTERFQNAADL
QNYVHNMFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDPADGNEVYATNVVKELTEAEARNLNSFESLIDHNI
LSAREYQSGDYERNGYYTIKLFAPIYSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLY
GKERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTKTINNVDELQALMDQAVLKDA
EGPRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK

Specific function: Zinc metalloproteinase which cleaves human immunoglobulin A1 (IgA1) in the hinge region

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall. Membrane; Multi-pass membrane protein. Secreted, cell wall; Peptidoglycan-anchor

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G5 domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IGA1_STRR6 (Q59947)

Other databases:

- EMBL:   U47687
- EMBL:   AE007317
- PIR:   B98002
- RefSeq:   NP_358636.1
- STRING:   Q59947
- MEROPS:   M26.001
- EnsemblBacteria:   EBSTRT00000014457
- GeneID:   933909
- GenomeReviews:   AE007317_GR
- KEGG:   spr:spr1042
- eggNOG:   NOG150396
- GeneTree:   EBGT00050000026618
- HOGENOM:   HBG703220
- OMA:   PEYTGVQ
- ProtClustDB:   CLSK2752100
- BioCyc:   SPNE171101:SPR1042-MONOMER
- BRENDA:   3.4.24.13
- InterPro:   IPR011098
- InterPro:   IPR011493
- InterPro:   IPR005877
- InterPro:   IPR019948
- InterPro:   IPR019931
- InterPro:   IPR008006
- InterPro:   IPR011505
- InterPro:   IPR001899
- TIGRFAMs:   TIGR01167
- TIGRFAMs:   TIGR01168

Pfam domain/function: PF07501 G5; PF07581 Glug; PF00746 Gram_pos_anchor; PF07580 Peptidase_M26_C; PF05342 Peptidase_M26_N; PF04650 YSIRK_signal

EC number: =3.4.24.13

Molecular weight: Translated: 218573; Mature: 218573

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS51109 G5; PS50847 GRAM_POS_ANCHORING; PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 1605-1605

Signals:

None

Transmembrane regions:

HASH(0x1ab3fe20)-; HASH(0x1b46ce38)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEECCCCCCC
EEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAALGIL
HHHHHHEEECCCCCCCCCCEEEEEEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
IFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLLNYNTDYELTSGEKLPLPKEI
HHHHHHHHHCCHHHEEEEEECCCCCCEEEEEEECCCEEEEEECCCEEECCCCCCCCCCCC
SGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPV
CCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHCCC
SSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNT
CCCCCCEEEEECCCCCCHHCCCCHHHHHCCCHHHHHHHHCCCCCHHHHCCCCHHHCCCCC
LNPQDEVLSGQLNKPELLYREETIETKIDFQEEIQENPDLAEGTVRVKQEGKLGKKVEIV
CCCHHHHHCCCCCCCCEEEEHHHHHHHCCHHHHHHCCCCCCCCEEEEECCCCCCCEEEEE
RIFSVNKEEVSREIVSTSTTAPSPRIVEKGTKKTQVIKEQPETGVEHKDVQSGAIVEPAI
EEEECCHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEECCCC
QPELPEAVVSDKGEPEVQPTLPEAVVTDKGETEVQPESPDTVVSDKGEPEQVAPLPEYKG
CCCCCHHHHCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHCC
NIEQVKPETPVEKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQEAENPVQPAEES
CHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCC
TTNSEKVSPDTSSENTGEVSSNPSDSTTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCC
TVEGTSNQETEKPVQPAEETQTNSGKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATK
CEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PENSGNTTSENGQTEPEKKLELRNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKS
CCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCCCCEEEEEEEC
SAFKDVYIPVASITEEKRNGQSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNF
CCCCEEEEEHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCH
TSFSNLVKAINQNPSGTYHLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYN
HHHHHHHHHHCCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHCCEEEECCCCCEEEEEE
LKKPLFENLSGATVEKLSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGG
CCHHHHHCCCCCEEHHEEECEEEECCCCCHHHHHHHCCCCCEEEEEEECEEEECCCCCCC
LLAKADQSSIAESSFKGRIVNTYETTDAYNIGGLVGHLTGKNASIAKSKATVTISSNTNR
HHHHCCHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCCCCEECCCEEEEEECCCCC
SDQTVGGLAGLVDQDAHIQNSYAEGDINNVKHFGKVAGVAGYLWDRTSGEEKHAGELTNV
CCHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LSDVNVTNGNAITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQ
HHHCCCCCCCEEEEEEECCCHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHCCEECHHH
IVSKKAEINPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVK
HHHHHCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEE
YGNLVKENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTD
CCCHHHHCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECC
FANLAEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTE
HHHHHHCCCCCCCEEECCCHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEH
LYLEDQFSKTKQNLGDSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEHHHHHHHHH
YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLASQH
HCCCCCEEEHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
GATDLFSTLEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYSIGVY
CHHHHHHHHHHHHHEECCCCCCCCCCCCCCCEEEEECHHHHHHHHHHCCCCCCEEEECHH
DRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALNDFVEEN
HHHHHHHHHHHHEEEHEEECCCCCEEEEEEHHHCCCCHHHHHCCCCHHHHHHHHHHHHHH
ARETAKRQRDHYDYWYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEAKFDSSNPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCH
MKNFFGPVGNKVVHNQHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDSDQDIYLGGYG
HHHHHCCCCCCEEECCCCCEECCCCEEEEEEEEECCCCCEEEEEECCCCCCCCEEECCCC
RRNGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVLDPTERFQNAADL
CCCCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHCCCCCCCCCCEEEEECHHHHHCCHHHH
QNYVHNMFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDPADGNEVYATNVVKE
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LTEAEARNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAPIYSALSSEKGTPGDLM
HHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCHHHH
GRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGKERGLVTDELVLKKVFDGK
HHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCC
YKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTKTINNVDELQALMDQAVLKDA
CHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHCC
EGPRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCH
>Mature Secondary Structure
MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEECCCCCCC
EEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAALGIL
HHHHHHEEECCCCCCCCCCEEEEEEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
IFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLLNYNTDYELTSGEKLPLPKEI
HHHHHHHHHCCHHHEEEEEECCCCCCEEEEEEECCCEEEEEECCCEEECCCCCCCCCCCC
SGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPV
CCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHCCC
SSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNT
CCCCCCEEEEECCCCCCHHCCCCHHHHHCCCHHHHHHHHCCCCCHHHHCCCCHHHCCCCC
LNPQDEVLSGQLNKPELLYREETIETKIDFQEEIQENPDLAEGTVRVKQEGKLGKKVEIV
CCCHHHHHCCCCCCCCEEEEHHHHHHHCCHHHHHHCCCCCCCCEEEEECCCCCCCEEEEE
RIFSVNKEEVSREIVSTSTTAPSPRIVEKGTKKTQVIKEQPETGVEHKDVQSGAIVEPAI
EEEECCHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCEECCCC
QPELPEAVVSDKGEPEVQPTLPEAVVTDKGETEVQPESPDTVVSDKGEPEQVAPLPEYKG
CCCCCHHHHCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHCC
NIEQVKPETPVEKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQEAENPVQPAEES
CHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCC
TTNSEKVSPDTSSENTGEVSSNPSDSTTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCC
TVEGTSNQETEKPVQPAEETQTNSGKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATK
CEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PENSGNTTSENGQTEPEKKLELRNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKS
CCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCCCCEEEEEEEC
SAFKDVYIPVASITEEKRNGQSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNF
CCCCEEEEEHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCH
TSFSNLVKAINQNPSGTYHLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYN
HHHHHHHHHHCCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHCCEEEECCCCCEEEEEE
LKKPLFENLSGATVEKLSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGG
CCHHHHHCCCCCEEHHEEECEEEECCCCCHHHHHHHCCCCCEEEEEEECEEEECCCCCCC
LLAKADQSSIAESSFKGRIVNTYETTDAYNIGGLVGHLTGKNASIAKSKATVTISSNTNR
HHHHCCHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCCCCEECCCEEEEEECCCCC
SDQTVGGLAGLVDQDAHIQNSYAEGDINNVKHFGKVAGVAGYLWDRTSGEEKHAGELTNV
CCHHHHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LSDVNVTNGNAITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQ
HHHCCCCCCCEEEEEEECCCHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHCCEECHHH
IVSKKAEINPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVK
HHHHHCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEE
YGNLVKENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTD
CCCHHHHCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEECC
FANLAEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTE
HHHHHHCCCCCCCEEECCCHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEH
LYLEDQFSKTKQNLGDSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEHHHHHHHHH
YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLASQH
HCCCCCEEEHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
GATDLFSTLEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYSIGVY
CHHHHHHHHHHHHHEECCCCCCCCCCCCCCCEEEEECHHHHHHHHHHCCCCCCEEEECHH
DRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALNDFVEEN
HHHHHHHHHHHHEEEHEEECCCCCEEEEEEHHHCCCCHHHHHCCCCHHHHHHHHHHHHHH
ARETAKRQRDHYDYWYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEAKFDSSNPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCH
MKNFFGPVGNKVVHNQHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDSDQDIYLGGYG
HHHHHCCCCCCEEECCCCCEECCCCEEEEEEEEECCCCCEEEEEECCCCCCCCEEECCCC
RRNGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVLDPTERFQNAADL
CCCCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHCCCCCCCCCCEEEEECHHHHHCCHHHH
QNYVHNMFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDPADGNEVYATNVVKE
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LTEAEARNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAPIYSALSSEKGTPGDLM
HHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCHHHH
GRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGKERGLVTDELVLKKVFDGK
HHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCC
YKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTKTINNVDELQALMDQAVLKDA
CHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHCC
EGPRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8926056; 11544234