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The map label for this gene is xerS

Identifier: 116516164

GI number: 116516164

Start: 1047609

End: 1048679

Strand: Direct

Name: xerS

Synonym: SPD_1023

Alternate gene names: 116516164

Gene position: 1047609-1048679 (Clockwise)

Preceding gene: 116517148

Following gene: 116516941

Centisome position: 51.2

GC content: 38.0

Gene sequence:

>1071_bases
ATGAAACGTGAGATTTTACTGGAACGAATCGACAAACTAAAACAACTCATGCCCTGGTATGTTCTGGAATACTACCAATC
TAAACTGGCTGTGCCCTACAGTTTTACAACCCTGTACGAATACCTTAAGGAATATGACCGATTTTTCAGCTGGGTTTTGG
AGTCTGGTATTTCAAACGCTGATAAAATATCCGATATTCCTTTATCAGTTTTGGAAAATATGTCTAAGAAAGACATGGAA
TCCTTTATCCTTTATCTACGTGAACGTCCCTTGCTGAATGCTAATACAACAAAACAAGGTGTTTCACAGACAACTATCAA
TCGAACCTTATCAGCACTTTCTAGTCTTTACAAGTATCTAACCGAGGAGGTTGAAAACGATCAGGGGGAACCTTATTTCT
ATCGTAATGTAATGAAAAAAGTTTCAACCAAGAAAAAGAAAGAAACCCTTGCTGCCAGAGCTGAAAATATCAAGCAAAAA
CTCTTTCTAGGTGATGAAACAGAAGGTTTTCTAACTTATATCGATCAAGAGCACCCACAACAGCTTTCAAATCGAGCTCT
CTCATCATTCAACAAAAATAAAGAACGAGATTTAGCCATTATTGCCCTTCTCTTGGCATCTGGTGTTCGCTTATCTGAAG
CTGTTAATCTAGATCTAAGAGATCTCAATCTAAAAATGATGGTTATTGATGTTACTCGAAAAGGTGGCAAACGTGACTCA
GTCAATGTCGCTGCTTTTGCTAAACCTTATTTAGAGAATTATCTGGCCATTCGGAATCAACGCTATAAAACGGAAAAAAC
AGATACAGCCCTTTTTTTAACTCTCTACAGAGGTGTTCCTAATCGTATCGATGCTTCTAGCGTTGAGAAAATGGTTGCTA
AATACTCAGAGGATTTTAAAGTACGTGTAACACCCCATAAACTGCGCCATACACTAGCAACTAGGCTCTATGATGCTACT
AAATCACAAGTTTTAGTCAGTCACCAACTAGGACATGCCAGCACACAAGTCACTGACCTCTATACCCATATTGTTAATGA
TGAACAAAAGAATGCTCTGGATAGTTTATGA

Upstream 100 bases:

>100_bases
TGAAAAACTCCTATAACATCTTTCCGAAAAACTATAATTTTCTTGAAAAATATACAAGTCTATGCTATACTACTAGTATA
CTTAATTATGGAGAAAATAC

Downstream 100 bases:

>100_bases
TTTTGCGTATTTTAAATTATGTAAATAAATATCAAAAAAAGAAGTTGGTTAGTTGGCCAACTTCTTTTTGATTTATCCAA
CTACCGCTTCAGCGATTTCT

Product: site-specific tyrosine recombinase XerS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKEYDRFFSWVLESGISNADKISDIPLSVLENMSKKDME
SFILYLRERPLLNANTTKQGVSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLDLRDLNLKMMVIDVTRKGGKRDS
VNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLYRGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDAT
KSQVLVSHQLGHASTQVTDLYTHIVNDEQKNALDSL

Sequences:

>Translated_356_residues
MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKEYDRFFSWVLESGISNADKISDIPLSVLENMSKKDME
SFILYLRERPLLNANTTKQGVSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLDLRDLNLKMMVIDVTRKGGKRDS
VNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLYRGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDAT
KSQVLVSHQLGHASTQVTDLYTHIVNDEQKNALDSL
>Mature_356_residues
MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKEYDRFFSWVLESGISNADKISDIPLSVLENMSKKDME
SFILYLRERPLLNANTTKQGVSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLDLRDLNLKMMVIDVTRKGGKRDS
VNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLYRGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDAT
KSQVLVSHQLGHASTQVTDLYTHIVNDEQKNALDSL

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerS subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=251, Percent_Identity=28.6852589641434, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789261, Length=288, Percent_Identity=25.3472222222222, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERS_STRP2 (Q04KF1)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816497.1
- ProteinModelPortal:   Q04KF1
- STRING:   Q04KF1
- EnsemblBacteria:   EBSTRT00000019358
- GeneID:   4442838
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1023
- eggNOG:   COG0582
- GeneTree:   EBGT00050000027386
- HOGENOM:   HBG515070
- OMA:   YDDMRRE
- ProtClustDB:   PRK05084
- GO:   GO:0005737
- HAMAP:   MF_01816
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109
- InterPro:   IPR004107
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz

EC number: NA

Molecular weight: Translated: 41172; Mature: 41172

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: ACT_SITE 210-210 ACT_SITE 234-234 ACT_SITE 306-306 ACT_SITE 309-309 ACT_SITE 332-332 ACT_SITE 341-341

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKEYDRFFSWVLESGISNA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
DKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVSQTTINRTLSALSSLYKYL
HHHHCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQKLFLGDETEGFLTYIDQEHPQ
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHH
QLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLDLRDLNLKMMVIDVTRKGGKRDS
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCEEECCEEEEEEEEECCCCCCCC
VNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLYRGVPNRIDASSVEKMVAKYSEDFK
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCE
VRVTPHKLRHTLATRLYDATKSQVLVSHQLGHASTQVTDLYTHIVNDEQKNALDSL
EEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCC
>Mature Secondary Structure
MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKEYDRFFSWVLESGISNA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
DKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVSQTTINRTLSALSSLYKYL
HHHHCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQKLFLGDETEGFLTYIDQEHPQ
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHH
QLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLDLRDLNLKMMVIDVTRKGGKRDS
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCEEECCEEEEEEEEECCCCCCCC
VNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLYRGVPNRIDASSVEKMVAKYSEDFK
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCE
VRVTPHKLRHTLATRLYDATKSQVLVSHQLGHASTQVTDLYTHIVNDEQKNALDSL
EEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA