Click here to switch to the map view.

The map label for this gene is cdd-1 [H]

Identifier: 116516117

GI number: 116516117

Start: 749946

End: 750335

Strand: Direct

Name: cdd-1 [H]

Synonym: SPD_0738

Alternate gene names: 116516117

Gene position: 749946-750335 (Clockwise)

Preceding gene: 116517157

Following gene: 116516951

Centisome position: 36.65

GC content: 41.54

Gene sequence:

>390_bases
ATGGCGACTACTGAGTTGATTGAACTGGCAATTGAAACCAGCAAACATGCCTATGTCCCCTATTCTCACTTTCCTATCGG
AGCAGTTTTAGTAGCCAAAGACGGAAGTGTTTACACGGGAGTGAATATCGAAAATGCTAGCTATCCTTTGACCAATTGCG
GTGAGAGAACAGCTATTTTTAAGGCTATATCTGAAGGCCAAAGAGAATTTTCAGAATTGATTGTCTATGGTCAAACTGAA
AAACCGATCTCGCCATGTGGTGCTTGTCGCCAAGTGATGGCTGAATTTTTTGAACAAGATCTAAAAGTGACCTTAGTCGC
AAAAGATAAATCGACGGTCGAGATGACGGTCGGGGAATTACTTCCATACTCTTTTACAGACTTAAACTAG

Upstream 100 bases:

>100_bases
GGAGCTCGTTCTTATGCAGATGCTCTTGCCTTTGTCGAAGCAGGTGCGACCCGTATCGGAACGTCAGCTGGGGTAGCTAT
TTTAAAAGGAGAATTGGCAG

Downstream 100 bases:

>100_bases
TCTGAGTCGCTCTCTGAGTGGCACGGTCCTTGTGGCCAACCAATCCATACTTGCAACATCGTTGCACATCTTATTTAGGA
GGTTCAGTAATGAACAAGAA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 129; Mature: 128

Protein sequence:

>129_residues
MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIENASYPLTNCGERTAIFKAISEGQREFSELIVYGQTE
KPISPCGACRQVMAEFFEQDLKVTLVAKDKSTVEMTVGELLPYSFTDLN

Sequences:

>Translated_129_residues
MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIENASYPLTNCGERTAIFKAISEGQREFSELIVYGQTE
KPISPCGACRQVMAEFFEQDLKVTLVAKDKSTVEMTVGELLPYSFTDLN
>Mature_128_residues
ATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIENASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEK
PISPCGACRQVMAEFFEQDLKVTLVAKDKSTVEMTVGELLPYSFTDLN

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=122, Percent_Identity=49.1803278688525, Blast_Score=120, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17551074, Length=123, Percent_Identity=46.3414634146341, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17540514, Length=126, Percent_Identity=40.4761904761905, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323274, Length=123, Percent_Identity=35.7723577235772, Blast_Score=93, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24582741, Length=131, Percent_Identity=41.2213740458015, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24582744, Length=139, Percent_Identity=35.2517985611511, Blast_Score=90, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19920920, Length=137, Percent_Identity=37.956204379562, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14175; Mature: 14044

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIENASYPLTNCGERTAIF
CCHHHHHHHHHHCCCCEECCCCCCCCEEEEEECCCCEEECEEECCCCCCCCCCCCHHHHH
KAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLKVTLVAKDKSTVEMTVGEL
HHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEHHHH
LPYSFTDLN
CCCCCCCCC
>Mature Secondary Structure 
ATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIENASYPLTNCGERTAIF
CHHHHHHHHHHCCCCEECCCCCCCCEEEEEECCCCEEECEEECCCCCCCCCCCCHHHHH
KAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLKVTLVAKDKSTVEMTVGEL
HHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEHHHH
LPYSFTDLN
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]