Click here to switch to the map view.

The map label for this gene is recG [H]

Identifier: 116516080

GI number: 116516080

Start: 1528243

End: 1530258

Strand: Reverse

Name: recG [H]

Synonym: SPD_1507

Alternate gene names: 116516080

Gene position: 1530258-1528243 (Counterclockwise)

Preceding gene: 116515765

Following gene: 116516924

Centisome position: 74.79

GC content: 46.73

Gene sequence:

>2016_bases
ATGAATCTACATCAACCCTTGCATGTCTTGCCTGGTGTGGGACCAAAGTCAGCAGAAAAATACGCCAAACTAGGAATTGA
AAACTTGCAAGATCTCTTGCTCTACTTTCCTTTCCGTTATGAAGACTTCAAAACCAAGCAGGTGCTGGAGCTGGAAGACG
GTGAGAAGGCAGTTCTTTCTGGTCAGGTAGTGACTCCTGCTAGTGTCCAGTATTATGGTTTCAAGCGCAATCGCCTGCGT
TTTAGTCTCAAGCAGGGAGAGGTCGTTTTTGCGGTGAATTTCTTTAACCAGCCCTATCTGGCTGATAAAATAGAGTTGGG
AGCAACCCTTGCTGTCTTTGGAAAATGGGACCGCGCTAAGGCTAGTCTGACTGGGATGAAGGTTCTGGCTCAGGTAGAAG
ATGACCTCCAGCCTGTCTATCGTCTGGCTCAGGGAATCAGTCAGGCCAGTCTGGTTAAGGTCATCAAGACGGCTTTTGAT
CAGGGACTGGACCTCTTGATAGAAGAAAATCTGCCCCAGTCTTTACTAGACAAATACAAACTCATGTCCCGTTGTCAGGC
AGTCCGAGCTATGCATTTTCCAAAGGATTTGGCAGAATACAAGCAGGCTCTTCGCCGTATCAAGTTTGAGGAACTCTTTT
ATTTCCAAATGCAGTTGCAGACGCTCAAGTCTGAAAATAGAGTTCAGGGAAGTGGTCTGGTTCTGAATTGGTCTCAGGAA
AAAGTGACAGCAGTTAAAGCAAGTCTTCCTTTTGCCCTGACCCAAGCTCAGGAAAAGAGTTTGCAGGAAATTTTAACTGA
TATGAAGTCCGACCACCACATGAATCGTCTCCTACAAGGGGATGTGGGGAGTGGAAAAACGGTAGTCGCTGGCTTGGCCA
TGTTTGCGGCAGTGACAGCAGGTTATCAGGCTGCCCTAATGGTACCAACAGAAATCCTCGCAGAGCAACACTTTGAGAGT
TTACAGAACCTTTTTCCCAATTTGAAACTGGCTCTCTTGACAGGTTCCTTGAAAGCTGCAGAAAAGAGAGAAGTCTTGGA
GACCATTGCCAAGGGTGAGGCTGATTTGATTATAGGAACTCACGCTCTGATACAAGATGGGGTGGAGTATGCTCGTCTTG
GTTTGATTATTATCGATGAGCAGCACCGTTTTGGTGTAGGGCAAAGGCGTATTTTACGGGAAAAAGGTGACAATCCAGAT
GTCCTCATGATGACGGCGACTCCCATTCCACGGACGCTTGCCATCACAGCCTTTGGAGATATGGATGTTTCCATTATCGA
CCAGATGCCAGCAGGTCGGAAGCCTATTGTGACGCGCTGGATCAAACATGAGCAACTACCTCAGGTCTTGACTTGGTTAG
AGGGGGAAATTCAAAAAGGTTCCCAAGCCTATGTCATCTCTCCTTTGATTGAAGAATCAGAAGCTCTAGATTTGAAAAAT
GCCATTGCCTTATCAGAGGAGTTGACGACTCATTTTGCAGGCAAGGCAGAGGTGGCTCTTCTACATGGTAGGATGAAGAG
TGACGAAAAAGACCAGATCATGCAGGATTTCAAGGAGAGAAAGACGGATATTCTGGTTTCGACGACGGTTATTGAGGTTG
GGGTCAACGTTCCCAATGCGACTGTCATGATTATCATGGATGCCGATCGCTTCGGTCTCAGTCAACTTCACCAGCTTAGA
GGTCGTGTCGGTCGGGGGGACAAGCAGTCCTACGCTGTTCTCGTTGCCAATCCCAAGACGGATTCTGGGAAAGACCGCAT
GCGCATCATGACAGAAACGACCAATGGATTTGTCCTTGCGGAGGAAGATTTGAAAATGCGTGGTTCTGGTGAGATTTTTG
GAACCAGACAGTCAGGACTTCCAGAGTTCCAAGTGGCTGATATTATCGAAGATTTTCCGATTTTAGAAGAAGCAAGAAAG
GTTGCTAGCTACATTAGTTCTATAGAAGCTTGGCAAGAAGATCCAGAGTGGCGCATGATTGCCCTTCATCTGGAAAAGAA
AGAACATCTGGATTAA

Upstream 100 bases:

>100_bases
TCAGGTAGCGACCTACCGCGTAACCATTAACTATGAGGTGGTTTGCCTCCTCAGCGACCGTATTCCGAGAGAATATTATT
AGAAAAGAAAGGAGTGGAGC

Downstream 100 bases:

>100_bases
GCTTTCTCTAAGGAAAACTTAAGCTAGTTTTTAGGTTTGGCTCTTATACTAAAGTCATCAAAAAGAAACGAGGACTCTCA
TATGACAGTAACGATTAAAG

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 671

Protein sequence:

>671_residues
MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFKTKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLR
FSLKQGEVVFAVNFFNQPYLADKIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQLQTLKSENRVQGSGLVLNWSQE
KVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNRLLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFES
LQNLFPNLKLALLTGSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRILREKGDNPD
VLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVLTWLEGEIQKGSQAYVISPLIEESEALDLKN
AIALSEELTTHFAGKAEVALLHGRMKSDEKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLR
GRVGRGDKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQVADIIEDFPILEEARK
VASYISSIEAWQEDPEWRMIALHLEKKEHLD

Sequences:

>Translated_671_residues
MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFKTKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLR
FSLKQGEVVFAVNFFNQPYLADKIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQLQTLKSENRVQGSGLVLNWSQE
KVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNRLLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFES
LQNLFPNLKLALLTGSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRILREKGDNPD
VLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVLTWLEGEIQKGSQAYVISPLIEESEALDLKN
AIALSEELTTHFAGKAEVALLHGRMKSDEKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLR
GRVGRGDKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQVADIIEDFPILEEARK
VASYISSIEAWQEDPEWRMIALHLEKKEHLD
>Mature_671_residues
MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFKTKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLR
FSLKQGEVVFAVNFFNQPYLADKIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQLQTLKSENRVQGSGLVLNWSQE
KVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNRLLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFES
LQNLFPNLKLALLTGSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRILREKGDNPD
VLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVLTWLEGEIQKGSQAYVISPLIEESEALDLKN
AIALSEELTTHFAGKAEVALLHGRMKSDEKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLR
GRVGRGDKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQVADIIEDFPILEEARK
VASYISSIEAWQEDPEWRMIALHLEKKEHLD

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=691, Percent_Identity=39.2185238784371, Blast_Score=414, Evalue=1e-116,
Organism=Escherichia coli, GI1787357, Length=401, Percent_Identity=37.6558603491272, Blast_Score=263, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 75248; Mature: 75248

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFKTKQVLELEDGEKAVLS
CCCCCCHHHCCCCCCCHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEE
GQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLADKIELGATLAVFGKWDRAK
CCEECCCCEEEECEECCCEEEEEECCCEEEEEEECCCCCCCCHHHCCCEEEEEECCCHHH
ASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFDQGLDLLIEENLPQSLLDKYK
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHH
LMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQLQTLKSENRVQGSGLVLNWSQE
HHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCH
KVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNRLLQGDVGSGKTVVAGLAMFAAVTA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
GYQAALMVPTEILAEQHFESLQNLFPNLKLALLTGSLKAAEKREVLETIAKGEADLIIGT
CCCEEEECHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEH
HALIQDGVEYARLGLIIIDEQHRFGVGQRRILREKGDNPDVLMMTATPIPRTLAITAFGD
HHHHHCCHHHHHEEEEEEECCHHCCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEECC
MDVSIIDQMPAGRKPIVTRWIKHEQLPQVLTWLEGEIQKGSQAYVISPLIEESEALDLKN
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHCCHHHHHHHH
AIALSEELTTHFAGKAEVALLHGRMKSDEKDQIMQDFKERKTDILVSTTVIEVGVNVPNA
HHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEEEEEECCCCCC
TVMIIMDADRFGLSQLHQLRGRVGRGDKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLA
EEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCEEEE
EEDLKMRGSGEIFGTRQSGLPEFQVADIIEDFPILEEARKVASYISSIEAWQEDPEWRMI
CCCCCCCCCCCEEECCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEEE
ALHLEKKEHLD
EEEECHHHCCC
>Mature Secondary Structure
MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFKTKQVLELEDGEKAVLS
CCCCCCHHHCCCCCCCHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEE
GQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLADKIELGATLAVFGKWDRAK
CCEECCCCEEEECEECCCEEEEEECCCEEEEEEECCCCCCCCHHHCCCEEEEEECCCHHH
ASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFDQGLDLLIEENLPQSLLDKYK
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHH
LMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQLQTLKSENRVQGSGLVLNWSQE
HHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCH
KVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNRLLQGDVGSGKTVVAGLAMFAAVTA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
GYQAALMVPTEILAEQHFESLQNLFPNLKLALLTGSLKAAEKREVLETIAKGEADLIIGT
CCCEEEECHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEH
HALIQDGVEYARLGLIIIDEQHRFGVGQRRILREKGDNPDVLMMTATPIPRTLAITAFGD
HHHHHCCHHHHHEEEEEEECCHHCCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEECC
MDVSIIDQMPAGRKPIVTRWIKHEQLPQVLTWLEGEIQKGSQAYVISPLIEESEALDLKN
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHCCHHHHHHHH
AIALSEELTTHFAGKAEVALLHGRMKSDEKDQIMQDFKERKTDILVSTTVIEVGVNVPNA
HHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEEEEEECCCCCC
TVMIIMDADRFGLSQLHQLRGRVGRGDKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLA
EEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCEEEE
EEDLKMRGSGEIFGTRQSGLPEFQVADIIEDFPILEEARKVASYISSIEAWQEDPEWRMI
CCCCCCCCCCCEEECCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEEE
ALHLEKKEHLD
EEEECHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8830261; 11463916 [H]