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The map label for this gene is pepX

Identifier: 116516024

GI number: 116516024

Start: 800905

End: 803178

Strand: Reverse

Name: pepX

Synonym: SPD_0787

Alternate gene names: 116516024

Gene position: 803178-800905 (Counterclockwise)

Preceding gene: 116515522

Following gene: 116516573

Centisome position: 39.25

GC content: 41.25

Gene sequence:

>2274_bases
ATGCGTTTTAATCAATATAGTTATATCAATTTTCCAAAAGAAAATGTCTTATCTGAACTAAAAAAATGTGGCTTTGATTT
ACAAAATACAGCCAATCACAAAGACTCACTTGAAACCTTTTTACGTCGTTTCTTTTTCACTTATCAAGACACCAACTACC
CACTTTCTATCCTAGCAGCTGATAAAAAAACAGACCTGCTGACATTTTTTCAATCAGAAGATGAACTGACAGCAGATATT
TTTTATACTGTTGCTTTTCAACTTTTAGGCTTTTCTTATTTGGTTGACTTCGAAGATAGTGACGTTTTTCGTAAAGAAAC
TGGATTTCCCATTATATATGGTGACTTGATTGAAAATCTCTATCAGTTACTCAATACTCGCACCAAAAAAGGAAATACTC
TTATCGACCAACTTGTTAGTGATGGTCTTATTCCGGAGGATAATGACTACCACTACTTTAACGGCAAGAGTTTGGCTACT
TTTTCTAACCAGGATGTCATTCGTGAAGTCGTTTACGTTGAGTCTCGTGTCGATACTGACCAAAAAGGGCTATCAGACCT
AGTAAAGGTTAGCATTATTCGCCCTCGTTTTGATGGAAAAATCCCTGCCATCATGACAGCCAGCCCTTATCATCAGGGAA
CCAATGACAAGGCTAGTGACAAGGCTCTCTACAAGATGGAGGGCGAGCTTGAGGTTAAGCTTCCTCACAAGATTGAGCTA
GAGAAACCTCAACTAAATCTCGTCCAACCCCAAGGTAAAGCTGAGCTTATAGCAGAGGCTGAGGAAAAGCTAACTCACAT
CAACTCTAGCTATACACTAAACGACTACTTCCTTCCGAGAGGCTTTGCCAATCTCTATGTCTCAGGTGTTGGTACCAAAG
ACTCGACAGGTTTCATGACTAATGGAGACTACCAGCAAATCGAGGCTTATAAAAATGTCATCGATTGGCTTAACGGCCGT
TGCCGTGCCTTTACTGATCACACGCGCCAGCGTCAAGTCAAGGCTGATTGGTCAAACGGAAAAGTTGCTACAACAGGACT
TTCCTATCTAGGTACCATGTCCAATGGTCTTGCGACTACAGGAGTCGATGGTTTAGAAGTTATCATTGCCGAGGCAGGAA
TTTCATCATGGTACAACTACTACCGTGAAAACGGTCTGGTGACTAGCCCAGGTGGTTATCCAGGTGAGGACTTTGACTCC
CTTGCTGAGTTAACCTATTCTCGTAATCTCTTAGCTGGCGACTATATCCGTGGCAATGAAGCTCACCAAGCTGACTTAGA
AAAAGTGAAAGCTCAGCTAGACCGAAAAACTGGGGACTACAATCAGTTTTGGCATGACCGCAATTATCTGCTCAATGCCC
ATAAAGTAAAGGCAGAGGTTGTCTTTACTCATGGTTCTCAGGATTGGAATGTCAAACCACTTCATGTTTACCAGATGTTC
CATGCTCTTCCTACTCATATAAACAAGCATCTCTTTTTCCATAATGGTGCCCATGTTTACATGAACAATTGGCAATCAAT
TGACTTCCGTGAGTCCATAAATGCCTTATTGACCAAGAAATTACTAGGACAGGAAACAGACTTTCAACTTCCTACTGTTA
TCTGGCAGGACAATACAGCTCCACAGACTTGGTTATCACTTGATAACTTCGGTGGGCAAGAAAACTGTGAAACCTTCTCA
CTTGGTCAAGAAGAGCAAGCTATTCAAAACCAGTACCCAGATAAGGATTTTGAGCGCTATGGTAAGACATACCAAACCTT
CAATACAGAGCTCTATCAAGGGAAAGCCAATCAGATTACTATTAACCTTCCTGTGACTAAAGATCTCCACCTAAACGGTC
GCGCTCAGCTCAATCTTCGTATCAAATCCAGTACAAACAAGGGGCTCTTATCTGCCCAACTGCTAGAATTTGGGCAAAAG
AAATACCTACAACCTTATCCAGCTATTTTAAGTGCTAGAACCATTGACAACGGTCGCTATCACATGTTGGAAAATCTCTG
TGAATTGCCATTTAGACCAGAGGCACAACGAGTCGTGACAAAAGGTTACCTTAATTTACAAAATAGAAATGATTTACTGT
TAGTAGAGGATATTACTGCAGATGAATGGATGGATGTTCAATTTGAACTGCAGCCAACTATTTACAAGCTAAAAGAAGGA
GACACTCTCCGTTTAGTCCTCTATACTACTGACTTTGAAATCACCATCCGTGACAATACAGACTACCACTTGACTGTCGA
CCTCGCTCAGTCCATGCTTACCTTACCTTGCTAA

Upstream 100 bases:

>100_bases
TTATTCATTTTTATTGGATTATTTCCTTTTGAAGTTAACAATTCCCTTTCTGCTTTTTTTTGATATAATAACCTTAACTG
TCATTCTATATGGAGGTTCT

Downstream 100 bases:

>100_bases
AAGGAGTTACATTATTATGAATAAATCAGAACACCGCCACCAACTTATACGCGCTCTTATCACAAAAAACAAGATTCATA
CACAGGCTGAGTTGCAAGCC

Product: x-prolyl-dipeptidyl aminopeptidase

Products: NA

Alternate protein names: X-Pro dipeptidyl-peptidase; X-prolyl-dipeptidyl aminopeptidase; X-PDAP

Number of amino acids: Translated: 757; Mature: 757

Protein sequence:

>757_residues
MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRFFFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADI
FYTVAFQLLGFSYLVDFEDSDVFRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKASDKALYKMEGELEVKLPHKIEL
EKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDYFLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGR
CRAFTDHTRQRQVKADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGGYPGEDFDS
LAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYLLNAHKVKAEVVFTHGSQDWNVKPLHVYQMF
HALPTHINKHLFFHNGAHVYMNNWQSIDFRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFS
LGQEEQAIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSSTNKGLLSAQLLEFGQK
KYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKGYLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEG
DTLRLVLYTTDFEITIRDNTDYHLTVDLAQSMLTLPC

Sequences:

>Translated_757_residues
MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRFFFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADI
FYTVAFQLLGFSYLVDFEDSDVFRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKASDKALYKMEGELEVKLPHKIEL
EKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDYFLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGR
CRAFTDHTRQRQVKADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGGYPGEDFDS
LAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYLLNAHKVKAEVVFTHGSQDWNVKPLHVYQMF
HALPTHINKHLFFHNGAHVYMNNWQSIDFRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFS
LGQEEQAIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSSTNKGLLSAQLLEFGQK
KYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKGYLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEG
DTLRLVLYTTDFEITIRDNTDYHLTVDLAQSMLTLPC
>Mature_757_residues
MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRFFFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADI
FYTVAFQLLGFSYLVDFEDSDVFRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKASDKALYKMEGELEVKLPHKIEL
EKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDYFLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGR
CRAFTDHTRQRQVKADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGGYPGEDFDS
LAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYLLNAHKVKAEVVFTHGSQDWNVKPLHVYQMF
HALPTHINKHLFFHNGAHVYMNNWQSIDFRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFS
LGQEEQAIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSSTNKGLLSAQLLEFGQK
KYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKGYLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEG
DTLRLVLYTTDFEITIRDNTDYHLTVDLAQSMLTLPC

Specific function: Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S15 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PEPX_STRP2 (Q04L26)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816272.1
- ProteinModelPortal:   Q04L26
- SMR:   Q04L26
- STRING:   Q04L26
- EnsemblBacteria:   EBSTRT00000020576
- GeneID:   4441586
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_0787
- eggNOG:   NOG04844
- GeneTree:   EBGT00050000027432
- HOGENOM:   HBG515455
- OMA:   NDWNVKP
- ProtClustDB:   PRK05371
- GO:   GO:0005737
- GO:   GO:0006508
- HAMAP:   MF_00698
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR008252
- InterPro:   IPR000383
- InterPro:   IPR015251
- PRINTS:   PR00923
- SMART:   SM00939
- SMART:   SM00940

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C; PF09168 PepX_N; SSF49785 Gal_bind_like; SSF81761 PepX_N

EC number: =3.4.14.11

Molecular weight: Translated: 86862; Mature: 86862

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: ACT_SITE 348-348 ACT_SITE 468-468 ACT_SITE 498-498

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRFFFTYQDTNYPLSILAA
CCCCCCCEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCEEEEEE
DKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDVFRKETGFPIIYGDLIENL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCHHHCCCCCEEEHHHHHHH
YQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLATFSNQDVIREVVYVESRVDTD
HHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCEEEEECCHHHHHHHHHHHHCCCCC
QKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKASDKALYKMEGELEVKLPHKIEL
HHHHHHHHEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEECCEEEEECCCEEEE
EKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDYFLPRGFANLYVSGVGTKDSTGFMT
CCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEECCEECCCCCCEEEEEECCCCCCCCCEE
NGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVKADWSNGKVATTGLSYLGTMSNGLATT
CCCHHHHHHHHHHHHHHCCCEEEEHHHHHHCEEEECCCCCEEEECCHHHHHHHCCCCEEC
GVDGLEVIIAEAGISSWYNYYRENGLVTSPGGYPGEDFDSLAELTYSRNLLAGDYIRGNE
CCCCEEEEEEHHCHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHCCCCEECCCCCCCC
AHQADLEKVKAQLDRKTGDYNQFWHDRNYLLNAHKVKAEVVFTHGSQDWNVKPLHVYQMF
CHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEEEEEEEEEEECCCCCCCCHHHHHHHH
HALPTHINKHLFFHNGAHVYMNNWQSIDFRESINALLTKKLLGQETDFQLPTVIWQDNTA
HHHHHHHCCEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
PQTWLSLDNFGGQENCETFSLGQEEQAIQNQYPDKDFERYGKTYQTFNTELYQGKANQIT
CHHEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHCCHHHHCCCHHCCCCCCEEE
INLPVTKDLHLNGRAQLNLRIKSSTNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRY
EEECCEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHEEEECCCCHH
HMLENLCELPFRPEAQRVVTKGYLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEG
HHHHHHHCCCCCCCHHHHHHHHEEEECCCCCEEEEEECCCCCEEEEEEEECCEEEEECCC
DTLRLVLYTTDFEITIRDNTDYHLTVDLAQSMLTLPC
CEEEEEEEEECEEEEEECCCCEEEEHHHHHHHHCCCC
>Mature Secondary Structure
MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRFFFTYQDTNYPLSILAA
CCCCCCCEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCEEEEEE
DKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDVFRKETGFPIIYGDLIENL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCHHHCCCCCEEEHHHHHHH
YQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLATFSNQDVIREVVYVESRVDTD
HHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCEEEEECCHHHHHHHHHHHHCCCCC
QKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKASDKALYKMEGELEVKLPHKIEL
HHHHHHHHEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEECCEEEEECCCEEEE
EKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDYFLPRGFANLYVSGVGTKDSTGFMT
CCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEECCEECCCCCCEEEEEECCCCCCCCCEE
NGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVKADWSNGKVATTGLSYLGTMSNGLATT
CCCHHHHHHHHHHHHHHCCCEEEEHHHHHHCEEEECCCCCEEEECCHHHHHHHCCCCEEC
GVDGLEVIIAEAGISSWYNYYRENGLVTSPGGYPGEDFDSLAELTYSRNLLAGDYIRGNE
CCCCEEEEEEHHCHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHCCCCEECCCCCCCC
AHQADLEKVKAQLDRKTGDYNQFWHDRNYLLNAHKVKAEVVFTHGSQDWNVKPLHVYQMF
CHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEEEEEEEEEEECCCCCCCCHHHHHHHH
HALPTHINKHLFFHNGAHVYMNNWQSIDFRESINALLTKKLLGQETDFQLPTVIWQDNTA
HHHHHHHCCEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
PQTWLSLDNFGGQENCETFSLGQEEQAIQNQYPDKDFERYGKTYQTFNTELYQGKANQIT
CHHEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHCCHHHHCCCHHCCCCCCEEE
INLPVTKDLHLNGRAQLNLRIKSSTNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRY
EEECCEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHEEEECCCCHH
HMLENLCELPFRPEAQRVVTKGYLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEG
HHHHHHHCCCCCCCHHHHHHHHEEEECCCCCEEEEEECCCCCEEEEEEEECCEEEEECCC
DTLRLVLYTTDFEITIRDNTDYHLTVDLAQSMLTLPC
CEEEEEEEEECEEEEEECCCCEEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA