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The map label for this gene is mraY

Identifier: 116515948

GI number: 116515948

Start: 304564

End: 305544

Strand: Direct

Name: mraY

Synonym: SPD_0307

Alternate gene names: 116515948

Gene position: 304564-305544 (Clockwise)

Preceding gene: 116517037

Following gene: 116515968

Centisome position: 14.88

GC content: 41.28

Gene sequence:

>981_bases
ATGTTTATTTCCATCAGTGCTGGAATTGTGACATTTTTACTAACTTTAGTAGGAATTCCGGCCTTTATCCAATTTTATAG
AAAGGCGCAAATTACAGGCCAGCAGATGCATGAGGATGTCAAACAGCATCAGGCAAAAGCTGGGACTCCTACAATGGGAG
GTTTGGTTTTCTTGATTACTTCTGTTTTGGTTGCTTTCTTTTTCGCCCTATTTAGTAGCCAATTCAGCAATAATGTGGGA
ATGATTTTGTTCATCTTGGTCTTGTATGGCTTGGTCGGATTTTTAGATGACTTTCTCAAGGTCTTTCGTAAAATCAATGA
GGGGCTTAATCCTAAGCAAAAATTAGCTCTTCAGCTTCTAGGTGGAGTTATCTTCTATCTTTTCTATGAGCGCGGTGGCG
ATATCCTGTCTGTCTTTGGTTATCCAGTTCATTTGGGATTTTTCTATATTTTCTTCGCTCTTTTCTGGCTAGTCGGTTTT
TCAAACGCAGTAAACTTGACAGACGGTGTTGACGGTTTAGCTAGTATTTCCGTTGTGATTAGTTTGTTTGCCTATGGAGT
TATTGCCTATGTGCAAGGTCAGATGGATATTCTTCTAGTGATTCTTGCCATGATTGGTGGTTTGCTCGGTTTCTTCATCT
TTAACCATAAGCCTGCCAAGGTCTTTATGGGTGATGTGGGAAGTTTGGCCCTAGGTGGGATGCTGGCAGCTATCTCTATG
GCTCTCCACCAGGAATGGACTCTCTTGATTATCGGAATTGTGTATGTTTTTGAAACAACTTCTGTTATGATGCAAGTCAG
TTATTTCAAACTGACAGGTGGTAAACGTATTTTCCGTATGACGCCTGTACATCACCATTTTGAGCTTGGGGGATTGTCTG
GTAAAGGAAATCCTTGGAGCGAGTGGAAGGTTGACTTCTTCTTTTGGGGAGTTGGGCTTCTAGCAAGTCTCCTGACCCTC
GCAATTTTGTATTTGATGTAA

Upstream 100 bases:

>100_bases
GAATTTCAAGGCTCGGGCTCTACTGTGCAGAAGCAAGATGTTCGTGCTAACACAGCTATCAAGGACATTAAAAAAATTAC
ATTAACTTTAGGAGACTAAT

Downstream 100 bases:

>100_bases
GAATGGCACCCTGATGTTTCAGGGTGTTTTTGTGTTTAAATACACAATGAAAATCAAAGAACAAACTAGAAAGCTAACTT
TAGGCTGCTCAAAATATAAT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQAKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVG
MILFILVLYGLVGFLDDFLKVFRKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
SNAVNLTDGVDGLASISVVISLFAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKPAKVFMGDVGSLALGGMLAAISM
ALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKRIFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTL
AILYLM

Sequences:

>Translated_326_residues
MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQAKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVG
MILFILVLYGLVGFLDDFLKVFRKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
SNAVNLTDGVDGLASISVVISLFAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKPAKVFMGDVGSLALGGMLAAISM
ALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKRIFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTL
AILYLM
>Mature_326_residues
MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQAKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVG
MILFILVLYGLVGFLDDFLKVFRKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
SNAVNLTDGVDGLASISVVISLFAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKPAKVFMGDVGSLALGGMLAAISM
ALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKRIFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTL
AILYLM

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=319, Percent_Identity=40.7523510971787, Blast_Score=178, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_STRP2 (Q04MC4)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_815824.1
- STRING:   Q04MC4
- EnsemblBacteria:   EBSTRT00000019456
- GeneID:   4441350
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_0307
- eggNOG:   COG0472
- GeneTree:   EBGT00050000027583
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 36064; Mature: 36064

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x198fa060)-; HASH(0x40f8da6c)-; HASH(0x176bc658)-; HASH(0xc11d608)-; HASH(0x40f9133c)-; HASH(0x187e4b78)-; HASH(0x17c9a66c)-; HASH(0x19b3ba60)-; HASH(0xae846f8)-; HASH(0x40f8d52c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQAKAGTPTMGGLVFLIT
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVFRKINEGLNPKQKLALQLL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGFSNAVNLTDGVDGLASISVVI
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
SLFAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKPAKVFMGDVGSLALGGMLAAISM
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHH
ALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKRIFRMTPVHHHFELGGLSGKGNPWS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCHHHHEECCCCCCCCCCC
EWKVDFFFWGVGLLASLLTLAILYLM
HHHHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQAKAGTPTMGGLVFLIT
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVFRKINEGLNPKQKLALQLL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGFSNAVNLTDGVDGLASISVVI
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
SLFAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKPAKVFMGDVGSLALGGMLAAISM
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHH
ALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKRIFRMTPVHHHFELGGLSGKGNPWS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCHHHHEECCCCCCCCCCC
EWKVDFFFWGVGLLASLLTLAILYLM
HHHHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA