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The map label for this gene is yycG [H]

Identifier: 116515922

GI number: 116515922

Start: 1113793

End: 1115142

Strand: Reverse

Name: yycG [H]

Synonym: SPD_1084

Alternate gene names: 116515922

Gene position: 1115142-1113793 (Counterclockwise)

Preceding gene: 116515650

Following gene: 116516804

Centisome position: 54.5

GC content: 39.85

Gene sequence:

>1350_bases
ATGCTTGATTTACTGAAACAAACCATTTTTACCAGAGATTTTATCTTTATCCTGATTTTGTTAGGTTTCATCCTTGTTGT
GACCCTCTTATTACTGGAAAATAGACGTGATAATATTCAGTTGAAGCAAATCAATCAAAAGGTTAAAGATTTGATTGCAG
GAGATTATTCCAAGGTTCTTGATATGCAAGGTGGGTCTGAAATCACCAATATTACCAATAATTTGAATGACTTGTCGGAG
GTTATTCGTCTCACTCAGGAAAATCTAGAACAAGAGAGTAAGAGGCTAAATAGTATTCTGTTTTATATGACAGATGGGGT
TCTTGCGACTAACCGTCGGGGTCAGATTATCATGATTAACGATACAGCCAAGAAGCAACTGGGGTTGGTTAAGGAAGATG
TTCTGAATAGAAGCATTTTGGAATTGCTCAAGATAGAAGAAAACTATGAATTGCGTGATTTGATTACCCAAAGTCCAGAA
TTGTTGCTAGATTCCCAAGATATCAATGGCGAATATTTGAACCTTCGAGTTCGCTTTGCCTTGATACGTCGAGAGTCTGG
CTTTATTTCAGGTTTGGTGGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAACGCGAACGAAGACTCTTTGTTT
CCAATGTTAGCCATGAGTTACGGACTCCTCTGACTAGCGTAAAATCCTATCTTGAAGCCTTGGATGAGGGGGCTTTGTGT
GAAACTGTAGCACCAGACTTTATCAAGGTTTCTCTTGATGAGACCAACCGTATGATGCGCATGGTGACGGATCTCCTCCA
TCTTTCACGTATTGATAATGCTACCAGTCACCTAGATGTGGAACTGATTAACTTCACTGCTTTTATTACCTTTATCCTCA
ATCGTTTTGACAAGATGAAAGGACAGGAAAAGGAGAAAAAATATGAGCTGGTGAGAGATTATCCCATCAATTCTATCTGG
ATGGAAATTGATACAGATAAGATGACGCAGGTTGTCGACAATATTTTAAATAATGCTATTAAGTATTCGCCAGATGGGGG
TAAAATCACTGTCAGAATGAAGACAACTGAAGACCAGATGATTTTATCCATTTCTGACCACGGTTTGGGGATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTCTATCGTGTGGATCGTGCTAGAAGTCGTGCACAAGGTGGTACAGGTCTAGGA
CTGTCTATCGCTAAAGAAATTATCAAACAACATAAGGGCTTTATTTGGGCCAAGAGTGAATACGGCAAGGGTTCAACCTT
TACCATTGTACTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Upstream 100 bases:

>100_bases
GATGTGACTGTACGACGTCTGCGTGAGAAGATTGAAGATACGCCCAGCCGACCAGAGTATATCTTGACGCGCCGTGGTGT
AGGGTATTACATGAGAAATA

Downstream 100 bases:

>100_bases
AATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAA
AGAAGCTTTTAGTAGATGCA

Product: sensory box sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQINQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Sequences:

>Translated_449_residues
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQINQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED
>Mature_449_residues
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQINQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=342, Percent_Identity=31.8713450292398, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1786783, Length=221, Percent_Identity=30.316742081448, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788393, Length=240, Percent_Identity=29.1666666666667, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI48994928, Length=376, Percent_Identity=26.8617021276596, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1788549, Length=403, Percent_Identity=25.0620347394541, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI145693157, Length=234, Percent_Identity=29.4871794871795, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=30.4166666666667, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788713, Length=225, Percent_Identity=26.6666666666667, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790346, Length=262, Percent_Identity=29.3893129770992, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790861, Length=204, Percent_Identity=30.8823529411765, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=30.7692307692308, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87081816, Length=238, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790551, Length=204, Percent_Identity=29.9019607843137, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082128, Length=245, Percent_Identity=26.1224489795918, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1790300, Length=246, Percent_Identity=28.0487804878049, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=28.7449392712551, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787894, Length=224, Percent_Identity=24.1071428571429, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1789808, Length=210, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787374, Length=242, Percent_Identity=28.099173553719, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789403, Length=210, Percent_Identity=31.4285714285714, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51713; Mature: 51713

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQINQKVKDLIAGDYSKVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHH
DMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMIN
HCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCEEEECCCCCEEEEE
DTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPELLLDSQDINGEYLNLRVRFA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHEEECCCCCCCEEEEEEEEE
LIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
EECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCH
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMK
HHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHCEEHHHHHHHHHHHHHHHHHHHC
GQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQM
CCHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHCCEEECCCCCEEEEEEEECCCCE
ILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLGLSIAKEIIKQHKGFIWAKSE
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEEEECC
YGKGSTFTIVLPYDKDAVKEEVWEDEVED
CCCCCEEEEEEECCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQINQKVKDLIAGDYSKVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHH
DMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMIN
HCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCEEEECCCCCEEEEE
DTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPELLLDSQDINGEYLNLRVRFA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHEEECCCCCCCEEEEEEEEE
LIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
EECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCH
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMK
HHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHCEEHHHHHHHHHHHHHHHHHHHC
GQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQM
CCHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHCCEEECCCCCEEEEEEEECCCCE
ILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLGLSIAKEIIKQHKGFIWAKSE
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEEEECC
YGKGSTFTIVLPYDKDAVKEEVWEDEVED
CCCCCEEEEEEECCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]