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The map label for this gene is engA [H]

Identifier: 116515879

GI number: 116515879

Start: 1541688

End: 1542998

Strand: Reverse

Name: engA [H]

Synonym: SPD_1519

Alternate gene names: 116515879

Gene position: 1542998-1541688 (Counterclockwise)

Preceding gene: 116517075

Following gene: 116516969

Centisome position: 75.41

GC content: 43.63

Gene sequence:

>1311_bases
ATGGCCCTACCAACTATTGCCATTGTAGGACGTCCCAATGTTGGGAAATCAACCCTATTTAATCGGATCGCTGGTGAGCG
AATCTCCATTGTAGAAGATGTCGAAGGAGTGACACGTGACCGTATTTATGCAACGGGTGAGTGGCTCAATCGTTCTTTTA
GCATGATTGATACAGGAGGAATTGATGATGTCGATGCTCCTTTCATGGAACAAATCAAGCACCAGGCAGAAATTGCCATG
GAAGAAGCAGATGTTATCGTCTTTGTCGTGTCCGGTAAGGAAGGAATTACCGATGCAGACGAATACGTAGCCCGTAAGCT
TTATAAGACCCACAAACCAGTTATCCTCGCAGTTAACAAGGTGGACAACCCTGAGATGCGAAATGATATCTATGATTTCT
ATGCCCTCGGTTTGGGTGAACCACTGCCTATCTCATCTGTCCATGGTATCGGTACAGGGGATGTACTAGATGCGATTGTG
GAAAACCTTCCAAATGAATATGAAGAAGAAAATCCAGATGTCATTAAGTTTAGCTTGATTGGTCGTCCTAACGTTGGAAA
ATCAAGCTTGATTAATGCTATCTTGGGAGAAGACCGTGTCATTGCCAGTCCTGTTGCTGGAACAACTCGTGACGCTATTG
ATACCCACTTTACAGATACAGATGGTCAAGAGTTTACCATGATTGATACGGCTGGTATGCGTAAGTCTGGTAAGGTTTAT
GAAAATACTGAGAAGTACTCTGTCATGCGTGCCATGCGTGCTATTGACCGTTCAGATGTGGTCTTAATGGTCATCAATGC
GGAAGAGGGGATTCGTGAATACGACAAGCGTATCGCTGGATTTGCTCATGAAGCTGGTAAAGGGATGATTATCGTGGTCA
ACAAGTGGGATACGCTTGAAAAAGATAACCACACTATGAAAAACTGGGAAGAAGATATCCGTGAGCAGTTCCAATACCTG
CCTTACGCACCGATTATCTTTGTATCAGCTTTAACCAAGCAACGTCTCCACAAACTTCCTGAGATGATTAAGCAAATCAG
CGAAAGTCAAAATACACGTATTCCATCAGCTGTCTTGAACGATGTCATCATGGATGCCATTGCCATCAACCCAACACCGA
CAGACAAAGGAAAACGTCTCAAGATTTTCTATGCGACCCAAGTGGCAACCAAACCACCAACCTTTGTCATCTTTGTCAAT
GAAGAAGAACTCATGCACTTTTCTTACCTGCGTTTCTTGGAAAATCAAATCCGCAAGGCCTTTGTTTTTGAGGGAACACC
GATTCATCTCATCGCAAGAAAACGCAAATAA

Upstream 100 bases:

>100_bases
AGCTGGAGTCAGCGTCTAGCAGAACAGTTTGGTCAAGCTGAACCAAGCTCAACTAGAAAAAATCTTGAACAGAAGAAATT
ATTGTAGAAAGTGAGAAATT

Downstream 100 bases:

>100_bases
AAAAGTAGAATCTGGAATGACAGTTCCGGATTTTTTTGATATAATAAAATAATAGAAAACGCTATCAAAAGAAGGGGGGA
TGTCGGTGATGGAACATTTG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAM
EEADVIVFVVSGKEGITDADEYVARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDGQEFTMIDTAGMRKSGKVY
ENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYL
PYAPIIFVSALTKQRLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFVN
EEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK

Sequences:

>Translated_436_residues
MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAM
EEADVIVFVVSGKEGITDADEYVARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDGQEFTMIDTAGMRKSGKVY
ENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYL
PYAPIIFVSALTKQRLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFVN
EEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK
>Mature_435_residues
ALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAME
EADVIVFVVSGKEGITDADEYVARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIVE
NLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDGQEFTMIDTAGMRKSGKVYE
NTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLP
YAPIIFVSALTKQRLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFVNE
EELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=457, Percent_Identity=37.199124726477, Blast_Score=302, Evalue=3e-83,
Organism=Escherichia coli, GI1788919, Length=165, Percent_Identity=34.5454545454545, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI2367268, Length=93, Percent_Identity=38.7096774193548, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=170, Percent_Identity=34.1176470588235, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI45550813, Length=190, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49083; Mature: 48952

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRSFSMIDTGG
CCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHCCHHHHHEEEEHHHHCCCCCEEECCC
IDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEYVARKLYKTHKPVILAVNK
CCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEC
VDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIVENLPNEYEEENPDVIKFSLI
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCCEEEEEEE
GRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDGQEFTMIDTAGMRKSGKVY
CCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCC
ENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTLE
CCHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
KDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQRLHKLPEMIKQISESQNTRIPSAVLN
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
DVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFVNEEELMHFSYLRFLENQIRKA
HHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHE
FVFEGTPIHLIARKRK
EEECCCCEEEEEECCC
>Mature Secondary Structure 
ALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRSFSMIDTGG
CCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHCCHHHHHEEEEHHHHCCCCCEEECCC
IDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEYVARKLYKTHKPVILAVNK
CCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEC
VDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIVENLPNEYEEENPDVIKFSLI
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCCEEEEEEE
GRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDGQEFTMIDTAGMRKSGKVY
CCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCC
ENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTLE
CCHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
KDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQRLHKLPEMIKQISESQNTRIPSAVLN
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
DVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFVNEEELMHFSYLRFLENQIRKA
HHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHE
FVFEGTPIHLIARKRK
EEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA