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The map label for this gene is eep [C]

Identifier: 116515700

GI number: 116515700

Start: 235503

End: 236762

Strand: Direct

Name: eep [C]

Synonym: SPD_0245

Alternate gene names: 116515700

Gene position: 235503-236762 (Clockwise)

Preceding gene: 116516628

Following gene: 116515963

Centisome position: 11.51

GC content: 42.54

Gene sequence:

>1260_bases
ATGCTCGGAATTTTAACCTTTATTCTGGTTTTCGGGATTATTGTAGTGGTGCACGAGTTCGGGCACTTCTACTTTGCCAA
GAAATCAGGGATTTTAGTACGTGAATTTGCCATCGGTATGGGACCTAAAATTTTTGCTCACATTGGCAAGGATGGAACGG
CCTATACCATTCGAATCTTGCCTCTGGGTGGCTATGTCCGCATGGCCGGTTGGGGTGATGATACAACTGAAATCAAGACA
GGAACGCCTGTTAGTTTGACACTTGCTGATGATGGTAAGGTTAAACGCATCAATCTCTCAGGTAAAAAATTGGATCAAAC
AGCCCTCCCTATGCAGGTGACTCAGTTTGATTTTGAAGACAAGCTCTTTATCAAAGGATTGGTTCTGGAAGAAGAAAAAA
CATTTGCAGTGGATCACGATGCAACGGTTGTGGAAGCAGATGGTACTGAGGTTCGGATTGCACCTTTAGATGTTCAATAT
CAAAATGCGACTATCTGGGGCAAACTGATTACCAATTTTGCAGGTCCTATGAACAATTTTATCTTAGGTGTCGTTGTTTT
TTGGGTTTTAATCTTTATGCAGGGTGGTGTCAGAGATGTTGATACCAATCAGTTCCATATCATGCCCCAAGGTGCCTTGG
CCAAGGTAGGAGTACCAGAAACGGCACAAATTACCAAGATTGGCTCACATGAGGTTAGCAACTGGGAAAGCTTGATCCAA
GCTGTGGAAACAGAAACCAAAGATAAGACGGCACCGACTTTGGATGTGACTATTTCTGAAAAGGGGAGTGACAAACAAGT
CACTGTTACACCCGAAGATAGTCAAGGTCGTTACCTTCTAGGTGTTCAACCGGGGGTTAAGTCAGATTTTCTATCCATGT
TTGTAGGTGGTTTTACAACTGCTGCTGACTCAGCTCTCCGAATTCTCTCAGCTCTGAAAAATCTGATTTTCCAACCGGAT
TTGAACAAGTTGGGTGGACCTGTTGCTATCTTTAAGGCAAGTAGTGATGCTGCTAAAAATGGAATTGAGAATATCTTGTA
CTTCTTGGCAATGATTTCCATCAATATTGGGATTTTTAATCTTATTCCGATTCCAGCCTTGGATGGTGGTAAGATTGTGC
TCAATATCCTAGAAGCCATCCGCCGCAAACCATTGAAACAAGAAATTGAAACCTATGTCACCTTGGCCGGAGTGGTCATC
ATGGTTGTCTTGATGATTGCTGTGACTTGGAATGACATTATGCGACTCTTTTTTAGATAA

Upstream 100 bases:

>100_bases
TGGACATGGTGGTGTTTTGGATCGTTTCGATAGTATGTTGCTTGTATTTCCAATCATGCACTTATTTGGACTCTTTTAAT
CAAAAGACGGAGGAAACGCT

Downstream 100 bases:

>100_bases
TCGAGGAATATTATGAAACAAAGTAAAATGCCTATCCCAACGCTTCGCGAAATGCCAAGCGATGCTCAAGTTATCAGCCA
TGCTCTTATGTTGCGTGCTG

Product: zinc metalloprotease Eep

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKIFAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKT
GTPVSLTLADDGKVKRINLSGKKLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGVPETAQITKIGSHEVSNWESLIQ
AVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQGRYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPD
LNKLGGPVAIFKASSDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETYVTLAGVVI
MVVLMIAVTWNDIMRLFFR

Sequences:

>Translated_419_residues
MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKIFAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKT
GTPVSLTLADDGKVKRINLSGKKLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGVPETAQITKIGSHEVSNWESLIQ
AVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQGRYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPD
LNKLGGPVAIFKASSDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETYVTLAGVVI
MVVLMIAVTWNDIMRLFFR
>Mature_419_residues
MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKIFAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKT
GTPVSLTLADDGKVKRINLSGKKLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGVPETAQITKIGSHEVSNWESLIQ
AVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQGRYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPD
LNKLGGPVAIFKASSDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETYVTLAGVVI
MVVLMIAVTWNDIMRLFFR

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M50B family

Homologues:

Organism=Escherichia coli, GI1786373, Length=228, Percent_Identity=28.5087719298246, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y242_STRR6 (Q8DRB1)

Other databases:

- EMBL:   AE007317
- PIR:   B97902
- RefSeq:   NP_357836.1
- ProteinModelPortal:   Q8DRB1
- SMR:   Q8DRB1
- STRING:   Q8DRB1
- MEROPS:   M50.004
- EnsemblBacteria:   EBSTRT00000016352
- GeneID:   933841
- GenomeReviews:   AE007317_GR
- KEGG:   spr:spr0242
- eggNOG:   COG0750
- GeneTree:   EBGT00050000028033
- HOGENOM:   HBG664087
- OMA:   HGTEFVV
- PhylomeDB:   Q8DRB1
- ProtClustDB:   CLSK873318
- BioCyc:   SPNE171101:SPR0242-MONOMER
- GO:   GO:0006508
- InterPro:   IPR004387
- InterPro:   IPR008915
- TIGRFAMs:   TIGR00054

Pfam domain/function: PF02163 Peptidase_M50

EC number: NA

Molecular weight: Translated: 45865; Mature: 45865

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 19-19

Signals:

None

Transmembrane regions:

HASH(0x15c8a4ec)-; HASH(0x17cfc8a0)-; HASH(0x1a3580ec)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKIFAHIGKDGTAYTIRIL
CHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEHHHCCCCCEEEEECCCCCEEEEEEE
PLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGKKLDQTALPMQVTQFDFED
ECCCEEEEECCCCCCCEEECCCCEEEEEECCCCEEEEECCCCCCCCCCCCEEEEECCCCC
KLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQYQNATIWGKLITNFAGPMNNF
CEEEEEEEEECCCEEEECCCCEEEECCCCEEEEEEEEEEECCCCHHHHHHHHHCCCHHHH
ILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGVPETAQITKIGSHEVSNWESLIQ
HHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEECCCCCCCEEEECCCCCHHHHHHHHH
AVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQGRYLLGVQPGVKSDFLSMFVGGFTT
HHHHCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCEEEEECCCCHHHHHHHHHHCHHH
AADSALRILSALKNLIFQPDLNKLGGPVAIFKASSDAAKNGIENILYFLAMISINIGIFN
HHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEE
LIPIPALDGGKIVLNILEAIRRKPLKQEIETYVTLAGVVIMVVLMIAVTWNDIMRLFFR
EEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKIFAHIGKDGTAYTIRIL
CHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEHHHCCCCCEEEEECCCCCEEEEEEE
PLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGKKLDQTALPMQVTQFDFED
ECCCEEEEECCCCCCCEEECCCCEEEEEECCCCEEEEECCCCCCCCCCCCEEEEECCCCC
KLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQYQNATIWGKLITNFAGPMNNF
CEEEEEEEEECCCEEEECCCCEEEECCCCEEEEEEEEEEECCCCHHHHHHHHHCCCHHHH
ILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGVPETAQITKIGSHEVSNWESLIQ
HHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEECCCCCCCEEEECCCCCHHHHHHHHH
AVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQGRYLLGVQPGVKSDFLSMFVGGFTT
HHHHCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCEEEEECCCCHHHHHHHHHHCHHH
AADSALRILSALKNLIFQPDLNKLGGPVAIFKASSDAAKNGIENILYFLAMISINIGIFN
HHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEE
LIPIPALDGGKIVLNILEAIRRKPLKQEIETYVTLAGVVIMVVLMIAVTWNDIMRLFFR
EEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11544234