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The map label for this gene is yycF [H]

Identifier: 116515650

GI number: 116515650

Start: 1115135

End: 1115839

Strand: Reverse

Name: yycF [H]

Synonym: SPD_1085

Alternate gene names: 116515650

Gene position: 1115839-1115135 (Counterclockwise)

Preceding gene: 116516670

Following gene: 116515922

Centisome position: 54.53

GC content: 41.84

Gene sequence:

>705_bases
ATGAAAAAAATACTAATTGTAGATGATGAGAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTATGA
AGTTGTAACTGCTTTTAATGGTCGTGAAGCGCTAGAGCAATTTGAAGCAGAGCAACCAGATATTATTATTCTGGATTTGA
TGCTTCCAGAAATTGATGGTTTAGAAGTTGCTAAGACCATTCGTAAGACAAGCAGTGTGCCCATTCTTATGCTTTCAGCC
AAAGATAGTGAATTTGATAAGGTTATCGGTTTGGAACTTGGGGCAGATGACTATGTAACGAAACCCTTCTCCAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTTCTGCGTCGTTCTCAACCTATGCCAGTAGATGGTCAGGAAGCAGATAGTAAACCTC
AACCTATCCAAATTGGGGATTTAGAAATTGTTCCAGACGCCTACGTGGCTAAAAAATATGGCGAAGAACTAGACTTAACC
CATCGTGAATTTGAGCTTTTGTATCATTTAGCATCGCATACAGGTCAAGTCATCACGCGCGAACACTTGCTTGAGACTGT
CTGGGGTTATGACTATTTTGGTGATGTCCGCACAGTTGATGTGACTGTACGACGTCTGCGTGAGAAGATTGAAGATACGC
CCAGCCGACCAGAGTATATCTTGACGCGCCGTGGTGTAGGGTATTACATGAGAAATAATGCTTGA

Upstream 100 bases:

>100_bases
CTGGCAGGCTTATGCACAAGCCAACTTAGACAGTAGCCAAGACTAGCTATTGTGTCTTCTGACTATTTTTTGGTATAATA
GTAGAGAAAAAGGTGAACAT

Downstream 100 bases:

>100_bases
TTTACTGAAACAAACCATTTTTACCAGAGATTTTATCTTTATCCTGATTTTGTTAGGTTTCATCCTTGTTGTGACCCTCT
TATTACTGGAAAATAGACGT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA

Sequences:

>Translated_234_residues
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA
>Mature_234_residues
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=38.2608695652174, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=40, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=36.6812227074236, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=34.9557522123894, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=37.7682403433476, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=37.117903930131, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=35.0877192982456, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=35.8407079646018, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1790860, Length=236, Percent_Identity=36.4406779661017, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=32.4894514767932, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=32.4786324786325, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=34.051724137931, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=34.061135371179, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=33.1896551724138, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=34.7457627118644, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=32.5, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788905, Length=119, Percent_Identity=32.7731092436975, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787487, Length=102, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=33.0578512396694, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790299, Length=101, Percent_Identity=29.7029702970297, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26816; Mature: 26816

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDG
CCEEEEEECCCCHHHHHHHCCCCCCEEEEEEECCHHHHHHHCCCCCCEEEEEEECCCCCC
LEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQ
HHHHHHHHHCCCCCEEEEECCCCCCHHEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCC
PMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLTHREFELLYHLASHTGQVITR
CCCCCCCCCCCCCCCEEECCEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHH
EHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCC
>Mature Secondary Structure
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDG
CCEEEEEECCCCHHHHHHHCCCCCCEEEEEEECCHHHHHHHCCCCCCEEEEEEECCCCCC
LEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQ
HHHHHHHHHCCCCCEEEEECCCCCCHHEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCC
PMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLTHREFELLYHLASHTGQVITR
CCCCCCCCCCCCCCCEEECCEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHH
EHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]