| Definition | Streptococcus pneumoniae D39, complete genome. |
|---|---|
| Accession | NC_008533 |
| Length | 2,046,115 |
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The map label for this gene is hsdR [H]
Identifier: 116515646
GI number: 116515646
Start: 463909
End: 466242
Strand: Reverse
Name: hsdR [H]
Synonym: SPD_0455
Alternate gene names: 116515646
Gene position: 466242-463909 (Counterclockwise)
Preceding gene: 116516237
Following gene: 116516554
Centisome position: 22.79
GC content: 36.89
Gene sequence:
>2334_bases ATGGTTGAGTTTATAAAGTCTAAGAAAGAAATGAGTGAGGAGGATATTAAAGCAAATTTCATCACTCCTGCTATTGTATC CAAAGGATGGAAAAATGGTGAGCATATCGCTTACGAAGAATACTTCACTGATGGTCGAATTGAGGTTAGAGGAGATAAGG CTCGTCGTAAAGAAGGAAAAAAATCAGACTATTCACTGTATTACCAATTTGGAACTCGAATTGCAATTGTTGAGGCAAAG GATAATAAACACAGCGTTCGAGCAGGATTACAACAAGCTATTGAATATGGAGAGATTTTAGATGTTCCATTTGTTTATTC TTCGAATGGTGATGGCTTTATTGAACACGACCGTATCACGAGAGAAGAACGTGAGCTGGAGTTAGACGAATTCCCTACTC GTGAAGAATTATTTTCTCGTATGACGAAGGAAAAAGGATTGACGTACGAAATTACAGAAGCTATCTCAACTCCATACTAT ACAGACGCCTTCTCAATGAAAACGCCACGCTATTATCAGCAAATAGCTATCAACCGTACTATTGAAACAGTTGCCAGAGG ACAAAAACGAGTAATGTTTGTGATGGCAACAGGAACGGGGAAAACGTTCATGGCTTTTCAAATTATTCATCGCCTTCGAA AAGCTGGTTTGGCTAAACGAGTTTTATTCTTAGCGGATAGAAACATCTTAGTAGACCAAACGATGGCTGAAGACTTTAGG CCATTCGAAAAGGTAATGACGAAAATTACACCAAAACTTTTGACTGCTCCTGAAAAATTAAATTCTTTTGAAATTTATCT AGGGCTTTATCAGCAACTAACTGGTGAAGATGGAACTGAAACACATTATCAAAAATTTGACAAAGACTTCTTTGATTTAA TCGTAATTGATGAAGCGCACCGTGGTTCAGCTAAGGAAAACAGTAACTGGCGTAAGATAATTGATTATTTCAGTTCTGCG ACACAGATTGGGATGACCGCTACTCCTAAAGAAACCAAGAATGCTTCCAATACGGAATACTTTGGTGAGCCAATCTATAC TTATAGTTTAAAACAGGGAATCGAGGATGGTTTTTTGGCTCCATATCGTGTTATGAGAGTTAATTTAGATGTAGATGTGG ATGGTTATCGTCCAGAAACTGGAAAAGTTGATGCTAACGGACAATTAATAGAAGATAGGTACTACGGCAGGAAAGATTTT GATAAAACCATTGTCATTGATGATAGAACGCAAAGAGTTGCCAAGTTTGTTTCTGATTATATGAAGCAAAACAATGCACG ATTTGATAAAACAATTGTTTTTTGTGTTGATATTGACCATGCCGAGCGAATGCGTGCTGCACTTGTAAAAGAGAATCTAG ACTTAGTCCAAGAAGACTATCGTTATGTCATGCAAGTAACTGGTGACAACGCTGAAGGAAAAGCTCAACTGGATAACTTT ATGGATGTCAATTCTAATTTTCCCGCTATTGTAACAACGTCTAAATTATTAACGACAGGAGTTAATGCTAAAACATGTCG TTTGATTGTTTTAGACTCTAATATCCAATCCATGACTGAATTTAAACAAATTATTGGTCGTGGCACACGTCTTTATCCTC AAAAGGGGAAAGAATTTTTTACGATTATTGATTTTCGAAATGTTACCAATTTGTTTGCTGACCCTGATTTTGATGGTGAT CCAGTGAAGGTGCTGGAAACAGGTGCGAAAACAGTCAGTGGTTCTACGCCCGGTTTCGTAAGTGAGGAAGGTGACCCAGT AGAAAAATATATCGTTACAGACAAGCAGGTTACCATTCTTAATTCTACTGTTCAAGTATTGGATGAAAACGGGAAACTGA TTACCGAAAGCCTGACCGACTACACTCGGAAGAATATCTTAGGTAGCTACGCCACTTTGAACGATTTTATCACAGTTTGG CATACGGCGGATAAAAAGAAGCTTATCTTAGACGAACTTTATAAAAAAGGAGTTTATCTAGATGCTATTCGAGAGTCGGA GGGAATATCAGAACAAGAAATCGATGATTTTGATTTACTCCTAAAACTTGCCTATGGTCAAAAAGAATTAACCAAAACGG AACGTATCAATAAGCTCAAACAAAGCGGATATTTATATAAATATAGTGAGGAAGCGCGTGCTGTTTTGGAAATTTTACTG AACAAATACATGGATAAAGGTATTGGAGAACTCGAAAGCATTGAAACATTAAAACTTCCAGAATTTCAGATATATGGTGG AACCTTCAAAATCATCAATACTTATTTTGGAGATAAAAAACGATATTTACAAGCAATTAAAGAATTGGAGCAAGAGCTAT TTACAGTAGCTTAA
Upstream 100 bases:
>100_bases TTAGCAGAGTATTTTTATAAGTGTGATATAATAGAAGTATAATTTGTTCTGATAGTTTATTTTATGGAGAAGTAGATTTT TAGAATGCGGAGGGTTCAAT
Downstream 100 bases:
>100_bases TGAAAGGAAAGTATGTCAATTACATCATTTGTAAAAAGAATTCAAGATATCACTCGAAACGATGCTGGTGTTAATGGTGA TGCTCAACGTATTGAGCAAA
Product: type I restriction-modification system, R subunit
Products: NA
Alternate protein names: R.EcoAI [H]
Number of amino acids: Translated: 777; Mature: 777
Protein sequence:
>777_residues MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTDGRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAK DNKHSVRAGLQQAIEYGEILDVPFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLAKRVLFLADRNILVDQTMAEDFR PFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSA TQIGMTATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIEDRYYGRKDF DKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNF MDVNSNFPAIVTTSKLLTTGVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGD PVKVLETGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRKNILGSYATLNDFITVW HTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILL NKYMDKGIGELESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA
Sequences:
>Translated_777_residues MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTDGRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAK DNKHSVRAGLQQAIEYGEILDVPFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLAKRVLFLADRNILVDQTMAEDFR PFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSA TQIGMTATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIEDRYYGRKDF DKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNF MDVNSNFPAIVTTSKLLTTGVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGD PVKVLETGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRKNILGSYATLNDFITVW HTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILL NKYMDKGIGELESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA >Mature_777_residues MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTDGRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAK DNKHSVRAGLQQAIEYGEILDVPFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLAKRVLFLADRNILVDQTMAEDFR PFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSA TQIGMTATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIEDRYYGRKDF DKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNF MDVNSNFPAIVTTSKLLTTGVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGD PVKVLETGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRKNILGSYATLNDFITVW HTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILL NKYMDKGIGELESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA
Specific function: The EcoAI enzyme recognizes 5'-GAGN(7)GTCA-3'. Subunit R is required for both nuclease and ATPase activities, but not for modification [H]
COG id: COG4096
COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 helicase C-terminal domain [H]
Homologues:
Organism=Escherichia coli, GI226510991, Length=575, Percent_Identity=28.1739130434783, Blast_Score=154, Evalue=3e-38, Organism=Escherichia coli, GI1788511, Length=407, Percent_Identity=24.3243243243243, Blast_Score=80, Evalue=5e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014001 - InterPro: IPR001650 - InterPro: IPR014021 - InterPro: IPR006935 - InterPro: IPR013670 - InterPro: IPR007409 [H]
Pfam domain/function: PF08463 EcoEI_R_C; PF04313 HSDR_N; PF04851 ResIII [H]
EC number: =3.1.21.3 [H]
Molecular weight: Translated: 89292; Mature: 89292
Theoretical pI: Translated: 5.22; Mature: 5.22
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTDGRIEVRGDKARRKEGK CCHHHHHHHHCCHHHHHHHCCCHHHHHCCCCCCCEEEEHHHCCCCEEEECCCHHHHCCCC KSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDVPFVYSSNGDGFIEHDRIT CCCCEEEEEECCEEEEEEECCCCHHHHHHHHHHHHHCCEECCCEEEECCCCCCEECCHHC REERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYYTDAFSMKTPRYYQQIAINRT CHHHHCCHHCCCCHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCCCCCCCHHHHHHHHHHH IETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLAKRVLFLADRNILVDQTMAEDFR HHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEHHHHHHCC PFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAH HHHHHHHHHCHHHHCCHHHCCCEEEHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEECCC RGSAKENSNWRKIIDYFSSATQIGMTATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLA CCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCEEEEHHHHCCCCCCCC PYRVMRVNLDVDVDGYRPETGKVDANGQLIEDRYYGRKDFDKTIVIDDRTQRVAKFVSDY CEEEEEEEEEEECCCCCCCCCEECCCCCEECCCCCCCCCCCCEEEECCHHHHHHHHHHHH MKQNNARFDKTIVFCVDIDHAERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNF HHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHH MDVNSNFPAIVTTSKLLTTGVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFF HCCCCCCCEEEEEHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCEECCCCCCEEE TIIDFRNVTNLFADPDFDGDPVKVLETGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTIL EEEEEHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHEEECCCEEEEE NSTVQVLDENGKLITESLTDYTRKNILGSYATLNDFITVWHTADKKKLILDELYKKGVYL HHHHHHHCCCCCEEHHHHHHHHHHHHHCCHHHHHHHEEEEECCCCHHHHHHHHHHCCCEE DAIRESEGISEQEIDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILL EEHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHH NKYMDKGIGELESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA HHHHHCCCCCHHCCCEECCCCEEEECCEEEEEHHHHCCHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTDGRIEVRGDKARRKEGK CCHHHHHHHHCCHHHHHHHCCCHHHHHCCCCCCCEEEEHHHCCCCEEEECCCHHHHCCCC KSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDVPFVYSSNGDGFIEHDRIT CCCCEEEEEECCEEEEEEECCCCHHHHHHHHHHHHHCCEECCCEEEECCCCCCEECCHHC REERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYYTDAFSMKTPRYYQQIAINRT CHHHHCCHHCCCCHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCCCCCCCHHHHHHHHHHH IETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLAKRVLFLADRNILVDQTMAEDFR HHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEHHHHHHCC PFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAH HHHHHHHHHCHHHHCCHHHCCCEEEHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEECCC RGSAKENSNWRKIIDYFSSATQIGMTATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLA CCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCEEEEHHHHCCCCCCCC PYRVMRVNLDVDVDGYRPETGKVDANGQLIEDRYYGRKDFDKTIVIDDRTQRVAKFVSDY CEEEEEEEEEEECCCCCCCCCEECCCCCEECCCCCCCCCCCCEEEECCHHHHHHHHHHHH MKQNNARFDKTIVFCVDIDHAERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNF HHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHH MDVNSNFPAIVTTSKLLTTGVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFF HCCCCCCCEEEEEHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCEECCCCCCEEE TIIDFRNVTNLFADPDFDGDPVKVLETGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTIL EEEEEHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHEEECCCEEEEE NSTVQVLDENGKLITESLTDYTRKNILGSYATLNDFITVWHTADKKKLILDELYKKGVYL HHHHHHHCCCCCEEHHHHHHHHHHHHHCCHHHHHHHEEEEECCCCHHHHHHHHHHCCCEE DAIRESEGISEQEIDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILL EEHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHH NKYMDKGIGELESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA HHHHHCCCCCHHCCCEECCCCEEEECCEEEEEHHHHCCHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8412658 [H]