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The map label for this gene is yhdH [H]

Identifier: 116515423

GI number: 116515423

Start: 662111

End: 663496

Strand: Reverse

Name: yhdH [H]

Synonym: SPD_0642

Alternate gene names: 116515423

Gene position: 663496-662111 (Counterclockwise)

Preceding gene: 116515491

Following gene: 116516778

Centisome position: 32.43

GC content: 42.78

Gene sequence:

>1386_bases
ATGGTTTTCTTGACAGACCTTAGAAAACATAATAGGATAGTCAAGTCTATCAATCAAACAGAAGGCTATTTGACAACTCA
AGTAGCTTTTTCTTATTTTGAAAAAGGAGATCAGAGTTTAACTATGTCAGAAAAATCACAATGGGGGTCGAAACTTGGCT
TTATTCTAGCATCTGCTGGCTCGGTCATCGGGCTTGGTTCCGTTTGGAAGTTTCCCTACATGACTGCTGCTAATGGCGGT
GGAGGCTTTTTACTAATCTTTCTCATTTCCACTATTTTAATCGGTTTCCCTCTCCTGCTGGCTGAGTTTGCCCTTGGCCG
TAGTGCTGGCGTTTCCGCTATCAAAACCTTTGGAAAACTGGGCAAGAATAACAAGTACAACTTTATCGGTTGGATTGGCG
CCTTTGCCCTCTTTATCCTCTTATCTTTTTACAGTGTTATCGGAGGATGGATTCTAGTCTATCTAGGTATTGAGTTTGGG
AAATTGTTCCAACTTGGTGGAACGGGTGATTATGCTCAGTTATTTACTTCAATCATTTCAAATCCAGCCATTGCTCTAGG
AGCTCAAGCGACCTTTATCCTATTGAATATCTTCATTGTATCACGTGGGGTTCAAAAAGGGATTGAAAGAGCTTCGAAAG
TCATGATGCCCCTGCTCTTTATCATCTTTGTCGTCATCATCGAACGCTCTCTCAGTTTGCCAAATGCCATGGAAGGGGTT
CTTTACTTCCTCAAACCAGATTTTTCAAAACTGACTAGCGCTGGTCTCCTCTATGCTCTGAGACAATCTTTCTTTGCCCT
CTCACTAGGGGTTACAGCCATGTTGACCTATGCTTCTTACTTGGACAAGAAAACCAATCTGGTCCAGTCAAGAATCTCCA
TCGTAGCCATGAATATCTCGGTATCCATCATGGCAGGTCTAGCCATTTTCCAAGCTCGGTCCCCCTTCAATATCCAGTCT
GAAGGGGGACCGAGCTTGGTCTTTATCGTCTTGCCTCAACTCTTTGACAAGATGCCTTTTGGAACCATTTTCTATGTCCT
CTTCCTCTTTGCGACTGTCACTTCTTCTGTCGTTATGCTGGAAATCAATGTAGACAATATCACCAATCAGGACAACAGCA
AGCGTGCTAAATGGAGTGTTATTTTAGGAATTTTGACCTTTGTCTTTGGCATTCCTTCAGCCCTATCTTACGGTGTCATG
GCGGATGTTCACATTTTTGGTAAAGCCTTCTTTGACGCTATGGACTTCTTGGTTTCCAATCTCCTCATGCCATTTGGAGC
TCTCTTCCTTTCACTTTTTACAGGCTATATCTTTAAAAAGGCTCTTGCAATGGAGGAACTCCATCTCGATGAAAGAGCAT
GGAAACAAGGACTGTTCCAAGTCTGA

Upstream 100 bases:

>100_bases
TTCTTTTATATGGTACATGATTTCCTCCTTACAATGATAGTATAACCCCTCCCCTTAGGTCAGAGTCAAGCGTTTTTGAG
AAAGGTGTGAAAACTTGAAA

Downstream 100 bases:

>100_bases
CTCTTCCTTCTTCGTTTCGTCATTCCAATCATCATCGTGGTCTTCATCGCCCAATTTATGTAATCAAAAGGACTTGAGTA
ATGAACTCAGGTCCTTTCTT

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSEKSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGG
GGFLLIFLISTILIGFPLLLAEFALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
KLFQLGGTGDYAQLFTSIISNPAIALGAQATFILLNIFIVSRGVQKGIERASKVMMPLLFIIFVVIIERSLSLPNAMEGV
LYFLKPDFSKLTSAGLLYALRQSFFALSLGVTAMLTYASYLDKKTNLVQSRISIVAMNISVSIMAGLAIFQARSPFNIQS
EGGPSLVFIVLPQLFDKMPFGTIFYVLFLFATVTSSVVMLEINVDNITNQDNSKRAKWSVILGILTFVFGIPSALSYGVM
ADVHIFGKAFFDAMDFLVSNLLMPFGALFLSLFTGYIFKKALAMEELHLDERAWKQGLFQV

Sequences:

>Translated_461_residues
MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSEKSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGG
GGFLLIFLISTILIGFPLLLAEFALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
KLFQLGGTGDYAQLFTSIISNPAIALGAQATFILLNIFIVSRGVQKGIERASKVMMPLLFIIFVVIIERSLSLPNAMEGV
LYFLKPDFSKLTSAGLLYALRQSFFALSLGVTAMLTYASYLDKKTNLVQSRISIVAMNISVSIMAGLAIFQARSPFNIQS
EGGPSLVFIVLPQLFDKMPFGTIFYVLFLFATVTSSVVMLEINVDNITNQDNSKRAKWSVILGILTFVFGIPSALSYGVM
ADVHIFGKAFFDAMDFLVSNLLMPFGALFLSLFTGYIFKKALAMEELHLDERAWKQGLFQV
>Mature_461_residues
MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSEKSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGG
GGFLLIFLISTILIGFPLLLAEFALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
KLFQLGGTGDYAQLFTSIISNPAIALGAQATFILLNIFIVSRGVQKGIERASKVMMPLLFIIFVVIIERSLSLPNAMEGV
LYFLKPDFSKLTSAGLLYALRQSFFALSLGVTAMLTYASYLDKKTNLVQSRISIVAMNISVSIMAGLAIFQARSPFNIQS
EGGPSLVFIVLPQLFDKMPFGTIFYVLFLFATVTSSVVMLEINVDNITNQDNSKRAKWSVILGILTFVFGIPSALSYGVM
ADVHIFGKAFFDAMDFLVSNLLMPFGALFLSLFTGYIFKKALAMEELHLDERAWKQGLFQV

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507043, Length=414, Percent_Identity=27.0531400966184, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI21361581, Length=488, Percent_Identity=25.6147540983607, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI7657587, Length=466, Percent_Identity=24.8927038626609, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI188528618, Length=353, Percent_Identity=25.2124645892351, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI171184408, Length=417, Percent_Identity=25.4196642685851, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI171184406, Length=417, Percent_Identity=25.4196642685851, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI171184404, Length=417, Percent_Identity=25.4196642685851, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI92859670, Length=454, Percent_Identity=24.0088105726872, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI134304856, Length=357, Percent_Identity=27.1708683473389, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4507041, Length=366, Percent_Identity=24.5901639344262, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI197276623, Length=352, Percent_Identity=25.2840909090909, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI54607094, Length=352, Percent_Identity=25.2840909090909, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI58219014, Length=306, Percent_Identity=27.1241830065359, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI33354281, Length=312, Percent_Identity=25, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI5032097, Length=365, Percent_Identity=25.7534246575342, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI194018524, Length=298, Percent_Identity=25.503355704698, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI289191351, Length=362, Percent_Identity=24.8618784530387, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4557046, Length=362, Percent_Identity=24.8618784530387, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI289191377, Length=360, Percent_Identity=25, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI218563756, Length=357, Percent_Identity=25.7703081232493, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI11181770, Length=312, Percent_Identity=25.6410256410256, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI51468073, Length=295, Percent_Identity=23.728813559322, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI21361693, Length=128, Percent_Identity=35.15625, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI67782313, Length=100, Percent_Identity=34, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI67782317, Length=75, Percent_Identity=41.3333333333333, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI67782315, Length=75, Percent_Identity=41.3333333333333, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI12408638, Length=292, Percent_Identity=24.6575342465753, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI197276625, Length=118, Percent_Identity=33.0508474576271, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI300360519, Length=271, Percent_Identity=24.7232472324723, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71995588, Length=415, Percent_Identity=25.5421686746988, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17554804, Length=368, Percent_Identity=26.0869565217391, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25146584, Length=389, Percent_Identity=24.4215938303342, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17555248, Length=115, Percent_Identity=37.3913043478261, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI133952791, Length=118, Percent_Identity=33.8983050847458, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17535731, Length=113, Percent_Identity=31.858407079646, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17542050, Length=120, Percent_Identity=28.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17136952, Length=430, Percent_Identity=23.4883720930233, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI281364394, Length=451, Percent_Identity=24.1685144124169, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28574704, Length=451, Percent_Identity=24.1685144124169, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17136950, Length=451, Percent_Identity=24.1685144124169, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28574702, Length=451, Percent_Identity=24.1685144124169, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24762620, Length=357, Percent_Identity=26.0504201680672, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45551088, Length=362, Percent_Identity=26.2430939226519, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24652942, Length=362, Percent_Identity=26.2430939226519, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI281363702, Length=385, Percent_Identity=28.051948051948, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI281364136, Length=377, Percent_Identity=25.1989389920424, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24661428, Length=392, Percent_Identity=25.5102040816327, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI281363700, Length=350, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI19921936, Length=398, Percent_Identity=25.6281407035176, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI19921352, Length=418, Percent_Identity=22.9665071770335, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24584353, Length=418, Percent_Identity=22.9665071770335, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24655079, Length=298, Percent_Identity=27.8523489932886, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281365034, Length=411, Percent_Identity=23.1143552311436, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI221329674, Length=460, Percent_Identity=23.695652173913, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24639514, Length=460, Percent_Identity=23.695652173913, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24639516, Length=296, Percent_Identity=25.3378378378378, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24582567, Length=348, Percent_Identity=24.7126436781609, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639853, Length=420, Percent_Identity=23.3333333333333, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI45551183, Length=161, Percent_Identity=27.3291925465839, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45550877, Length=161, Percent_Identity=27.3291925465839, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24654186, Length=119, Percent_Identity=32.7731092436975, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 50646; Mature: 50646

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSEKSQWGSKLGFILASAG
CEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCC
SVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAEFALGRSAGVSAIKTFGKL
CEEECCCHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
GKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFGKLFQLGGTGDYAQLFTSIIS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHC
NPAIALGAQATFILLNIFIVSRGVQKGIERASKVMMPLLFIIFVVIIERSLSLPNAMEGV
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LYFLKPDFSKLTSAGLLYALRQSFFALSLGVTAMLTYASYLDKKTNLVQSRISIVAMNIS
EEHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHH
VSIMAGLAIFQARSPFNIQSEGGPSLVFIVLPQLFDKMPFGTIFYVLFLFATVTSSVVML
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHCCEEEE
EINVDNITNQDNSKRAKWSVILGILTFVFGIPSALSYGVMADVHIFGKAFFDAMDFLVSN
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMPFGALFLSLFTGYIFKKALAMEELHLDERAWKQGLFQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSEKSQWGSKLGFILASAG
CEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCC
SVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAEFALGRSAGVSAIKTFGKL
CEEECCCHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
GKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFGKLFQLGGTGDYAQLFTSIIS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHC
NPAIALGAQATFILLNIFIVSRGVQKGIERASKVMMPLLFIIFVVIIERSLSLPNAMEGV
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LYFLKPDFSKLTSAGLLYALRQSFFALSLGVTAMLTYASYLDKKTNLVQSRISIVAMNIS
EEHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHH
VSIMAGLAIFQARSPFNIQSEGGPSLVFIVLPQLFDKMPFGTIFYVLFLFATVTSSVVML
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHCCEEEE
EINVDNITNQDNSKRAKWSVILGILTFVFGIPSALSYGVMADVHIFGKAFFDAMDFLVSN
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMPFGALFLSLFTGYIFKKALAMEELHLDERAWKQGLFQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]